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Evaluation of additives on reversed-phase chromatography of monoclonal antibodies using a 1000Å stationary phase (2019)
Journal Article
McCalley, D. V., & Guillarme, D. (in press). Evaluation of additives on reversed-phase chromatography of monoclonal antibodies using a 1000Å stationary phase. Journal of Chromatography A, 460562. https://doi.org/10.1016/j.chroma.2019.460562

A wide pore (1000 Å) diphenyl stationary phase was evaluated for the analysis of monoclonal antibodies (mAbs), comparing a conventional mobile phase of acetonitrile-water containing overall 0.1 % trifluoracetic acid (TFA) with a similar mobile phase... Read More

An investigation into the regulation of transcription of the splice factor kinase gene SRPK1 in prostate and leukaemia cancer cell lines (2019)
Thesis
Belali, T. An investigation into the regulation of transcription of the splice factor kinase gene SRPK1 in prostate and leukaemia cancer cell lines. (Thesis). University of the West of England. Retrieved from https://uwe-repository....ribe.com/output/1490649

The SRPK1 gene encodes a protein kinase that phosphorylates a class of splice factors called serine/arginine-rich proteins (SR proteins) modifying their ability to regulate alternative pre-mRNA splicing. Studies have linked high SRPK1 levels to tumou... Read More

Network theory and the resilience of redox signaling (2019)
Journal Article
Hancock, J. T., Veal, D., & Hancock, A. L. (2019). Network theory and the resilience of redox signaling. Reactive Oxygen Species, 8(23), 245-257

The redox status inside and around cells is critically important to control, being used to maintain reduced compounds in the correct state and for cell signaling mechanisms. A myriad of compounds and proteins are involved in a vast network system to... Read More

Abscisic acid induced a negative geotropic response in dark-incubated Chlamydomonas reinhardtii (2019)
Journal Article
Wilson, I., Ladomery, M., Macdonald, H., Al-Hijab, L., Gregg, A., & Davies, R. (2019). Abscisic acid induced a negative geotropic response in dark-incubated Chlamydomonas reinhardtii. Scientific Reports, 9, https://doi.org/10.1038/s41598-019-48632-0

The phytohormone abscisic acid (ABA) plays a role in stresses that alter plant water status and may also regulate root gravitropism and hydrotropism. ABA also exists in the aquatic algal progenitors of land plants, but other than its involvement in s... Read More

Pseudomonas daroniae sp. nov. and Pseudomonas dryadis sp. nov., isolated from pedunculate oak affected by acute oak decline in the UK (2019)
Journal Article
Bueno-Gonzalez, V., Brady, C., Denman, S., Plummer, S., Allainguillaume, J., & Arnold, D. (in press). Pseudomonas daroniae sp. nov. and Pseudomonas dryadis sp. nov., isolated from pedunculate oak affected by acute oak decline in the UK. International Journal of Systematic and Evolutionary Microbiology, https://doi.org/10.1099/ijsem.0.003615

An Electrocatalytic Screen-Printed Amperometric Sensor for the Selective Measurement of Thiamine (Vitamin B1) in Food Supplements (2019)
Journal Article
Smart, A., Westmacott, K. L., Crew, A., Doran, O., & Hart, J. P. (2019). An Electrocatalytic Screen-Printed Amperometric Sensor for the Selective Measurement of Thiamine (Vitamin B1) in Food Supplements. Biosensors, 9(3), 98. https://doi.org/10.3390/bios9030098

An electrocatalytic screen-printed sensor has been investigated for the measurement of the biologically important biomolecule vitamin B1 (thiamine) for the first time in food supplements. Under basic conditions, the vitamin was converted to its elect... Read More

Lemurs in cacao: presence and abundance within the shade plantations of northern Madagascar (2019)
Journal Article
Webber, A. D., Solofondranohatra, J. S., Razafindramoana, S., Fernandez, D., Parker, C. A., Steer, M., …Allainguillaume, J. (in press). Lemurs in cacao: presence and abundance within the shade plantations of northern Madagascar. Folia Primatologica, https://doi.org/10.1159/issn.0015-5713

The recognition that much biodiversity exists outside protected areas is driving research to understand how animals survive in anthropogenic landscapes. In Madagascar, cacao (Theobroma cacao) is grown under a mix of native and introduced exotic shad... Read More

Herbal teas and their health benefits: A scoping review (2019)
Journal Article
Poswal, F. S., Russell, G., Mackonochie, M., MacLennan, E., Adukwu, E. C., & Rolfe, V. (2019). Herbal teas and their health benefits: A scoping review. Plant Foods for Human Nutrition, 74(266-276), https://doi.org/10.1007/s11130-019-00750-w

Herbal teas are used as therapeutic vehicles in many forms of traditional medicine and are a popular global beverage. The purpose of this scoping review was to examine the evidence relating to the clinical efficacy and safety of herbal teas, and to i... Read More

Cumulative weather effects can impact across the whole life cycle (2019)
Journal Article
Hindle, B. J., Pilkington, J. G., Pemberton, J. M., & Childs, D. Z. (2019). Cumulative weather effects can impact across the whole life cycle. Global Change Biology, 25(10), 3282-3293. https://doi.org/10.1111/gcb.14742

Predicting how species will be affected by future climatic change requires the underlying environmental drivers to be identified. As vital rates vary over the lifecycle, structured population models derived from statistical environment-demography rel... Read More

Anodic stripping voltammetric determination of zinc at a 3-D printed carbon electrode (2019)
Presentation / Conference
Honeychurch, K. C., Rymansaib, Z., & Iravani, P. (2019, June). Anodic stripping voltammetric determination of zinc at a 3-D printed carbon electrode. Poster presented at 6th International Conference on Bio-Sensing Technology

• The possibility of a fully 3-D printing printed carbon nanofiber–graphite–polystyrene electrodes has been shown. • DPASV of Zn2+ showed stripping peaks, unaffected by other common heavy metals. • Conditions were optimised of the determination of... Read More

The role of ABA in regulating the movemement of chlamydomonas reinhardtii in response to stress (2019)
Thesis
Alhijab, L. The role of ABA in regulating the movemement of chlamydomonas reinhardtii in response to stress. (Thesis). The West England University. Retrieved from https://uwe-repository....ribe.com/output/1492927

Plant hormones such as auxin, gibberellin, cytokinin, ethylene, and abscisic acid play key roles in growth and developmental processes in higher plants such as Arabidopsis thaliana. However, the effect of these hormones on algal physiology is still u... Read More

The 2013–2016 Ebola epidemic: evaluating communication strategies between two affected countries in West Africa (2019)
Journal Article
Walker, B. F., & Adukwu, E. C. (2019). The 2013–2016 Ebola epidemic: evaluating communication strategies between two affected countries in West Africa. European Journal of Public Health, https://doi.org/10.1093/eurpub/ckz104

Abstract Background Ebola is a haemorrhagic disease with high fatality rates between 25 and 90%. The 2013–16 Ebola outbreak in West Africa was the largest to date with >28 000 cases and >11 000 fatalities. This outbreak exposed inadequacies in publ... Read More

The role of redox in signal transduction (2019)
Book Chapter
Hancock, J. The role of redox in signal transduction. In J. T. Hancock, & M. E. Conway (Eds.), Redox-Mediated Signal Transduction, 1-11. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9463-2_1

It is the functioning of efficient cell signaling which is vital for the survival of cells, whether it is a simple prokaryote or a complex eukaryote, including both animals and plants. Over many years various components have been identified and recog... Read More

Equations to support redox experimentation (2019)
Book Chapter
Hancock, J., & Whiteman, M. Equations to support redox experimentation. In J. T. Hancock, & M. E. Conway (Eds.), Redox-Mediated Signal Transduction, 183-195. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9463-2_15

Working with redox compounds needs to take into account the oxidation and reduction state of the compound under study. This redox state can be influenced by the media in which the compound is found, but will also be influenced by local environments.... Read More

Methods for the addition of redox Compounds (2019)
Book Chapter
Hancock, J. T. Methods for the addition of redox Compounds. In J. T. Hancock, & M. E. Conway (Eds.), Redox-Mediated Signal Transduction, 13-25. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9463-2_2

Often in redox biology experiments there is a need to add compounds which impinge on the redox of the cellular environment cell. Such compounds may include reactive oxygen species (ROS), such as hydrogen peroxide (H2O2), reactive nitrogen species suc... Read More

Bird's nest ferns as model systems and conservation tools (2019)
Thesis
Phillips, J. Bird's nest ferns as model systems and conservation tools. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/846445

We are in a race against time to understand the response of natural systems to climate change and anthropogenic disturbances, such as large scale land conversion for oil palm expansion. However, it is incredibly difficult to quantify multi-trophic bi... Read More

Investigating ROS, RNS, and H2S-sensitive signaling proteins (2019)
Book Chapter
Williams, E., Whiteman, M., Wood, M. E., Wilson, I., Ladomery, M., Allainguillaume, J., …Hancock, J. Investigating ROS, RNS, and H2S-sensitive signaling proteins. In J. T. Hancock, & M. E. Conway (Eds.), Redox-Mediated Signal Transduction, 27-42. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9463-2_3

The modification of proteins is a key way to alter their activity and function. Often thiols, cysteine residues, on proteins are attractive targets for such modification. Assuming that the thiol group is accessible then reactions may take place with... Read More

Resistance to echinocandin antifungal agents in the United Kingdom in clinical isolates of Candida glabrata: Fifteen years of interpretation and assessment (2019)
Journal Article
Fraser, M., Borman, A. M., Thorn, R., & Lawrance, L. M. (in press). Resistance to echinocandin antifungal agents in the United Kingdom in clinical isolates of Candida glabrata: Fifteen years of interpretation and assessment. Medical Mycology, https://doi.org/10.1093/mmy/myz053

Candidaemia is widely reported as the fourth most common form of bloodstream infection worldwide. Reports of breakthrough cases of candidaemia are increasing, especially in the context of a move away from azole antifungals as prophylactic or first li... Read More