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“They were aware of who I was as a person”: Patients’ and health professionals’ experiences of using the PEGASUS intervention to facilitate decision-making around breast reconstruction (2021)
Journal Article
Tollow, P., Paraskeva, N., Clarke, A., White, P., Powell, J., Cox, D., & Harcourt, D. (in press). “They were aware of who I was as a person”: Patients’ and health professionals’ experiences of using the PEGASUS intervention to facilitate decision-making around breast reconstruction. European Journal of Cancer Care, https://doi.org/10.1111/ecc.13464

Objective: Many women choose to have breast reconstruction after mastectomy, however, decision-making can be difficult and expectations are often unmet. The PEGASUS intervention (Patient Expectations and Goals: Assisting Shared Understanding of Surge... Read More about “They were aware of who I was as a person”: Patients’ and health professionals’ experiences of using the PEGASUS intervention to facilitate decision-making around breast reconstruction.

Modern Applications of Graph Theory (2021)
Book
Zverovich, V. (2021). Modern Applications of Graph Theory. Oxford, UK: Oxford University Press

This book discusses many cutting-edge applications of graph theory, such as traffic networks, navigable networks and optimal routing for emergency response, placement of electric vehicle charging stations, and graph-theoretic methods in molecular epi... Read More about Modern Applications of Graph Theory.

2008 financial crisis versus 2020 economic fallout: How COVID-19 might influence fertility treatment and live births (2021)
Journal Article
Gromski, P. S., Smith, A. D., Lawlor, D. A., Sharara, F. I., & Nelson, S. M. (2021). 2008 financial crisis versus 2020 economic fallout: How COVID-19 might influence fertility treatment and live births. Reproductive BioMedicine Online, 42(6), 1087-1096. https://doi.org/10.1016/j.rbmo.2021.03.017

Research question The economic and reproductive medicine response to the coronavirus disease 2019 (COVID-19) pandemic in the USA has reduced the affordability and accessibility of fertility care. What is the impact of the 2008 financial recession an... Read More about 2008 financial crisis versus 2020 economic fallout: How COVID-19 might influence fertility treatment and live births.

Protocol for a mixed methods study to inform the feasibility of undertaking a large-scale multicentre study comparing the clinical and patient-reported outcomes of oncoplastic breast conservation as an alternative to mastectomy with or without immediate b (2021)
Journal Article
Davies, C., Holcombe, C., Skillman, J., Whisker, L., Hollingworth, W., Conefrey, C., …Potter, S. (in press). Protocol for a mixed methods study to inform the feasibility of undertaking a large-scale multicentre study comparing the clinical and patient-reported outcomes of oncoplastic breast conservation as an alternative to mastectomy with or without immediate breast reconstruction in women unsuitable for standard breast conserving surgery (The ANTHEM feasibility study). BMJ Open,

Introduction: Approximately 40% of the 55,000 women diagnosed with breast cancer each year in the UK undergo mastectomy because they are considered unsuitable for standard breast conserving surgery (BCS) due to tumour size or multiple tumour foci. Ma... Read More about Protocol for a mixed methods study to inform the feasibility of undertaking a large-scale multicentre study comparing the clinical and patient-reported outcomes of oncoplastic breast conservation as an alternative to mastectomy with or without immediate b.

A case study in the e-assessment of statistics for non-specialists (2021)
Journal Article
Weir, I. S., Gwynllyw, D. R., & Henderson, K. L. (2021). A case study in the e-assessment of statistics for non-specialists. Journal of University Teaching and Learning Practice, 18(2),

The need to be able to choose, perform and interpret the results from appropriate statistical tests is ubiquitous in many STEM disciplines and beyond. In this case study, we illustrate a learning and assessment approach that has been used successfull... Read More about A case study in the e-assessment of statistics for non-specialists.

Advanced molecular characterization using Digital Spatial Profiling Technology on immuno-oncology targets in methylated compared with unmethylated IDH-wildtype glioblastoma (2021)
Journal Article
Ren, X., Barber, H., Tofias, A., Lander, B., Daniels, A., Gong, J., …Kurian, K. M. (2021). Advanced molecular characterization using Digital Spatial Profiling Technology on immuno-oncology targets in methylated compared with unmethylated IDH-wildtype glioblastoma. Journal of Oncology, 2021, https://doi.org/10.1155/2021/8819702

Introduction. Glioblastoma (GBM) is the most common primary adult brain tumour with a median overall survival (OS) of 12-15 months. Molecular characterization of multiple immunooncology targets in GBM may help target novel immunotherapeutic strategie... Read More about Advanced molecular characterization using Digital Spatial Profiling Technology on immuno-oncology targets in methylated compared with unmethylated IDH-wildtype glioblastoma.

A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder (2021)
Journal Article
Challapalli, A., Masson, S., White, P., Dailami, N., Pearson, S., Rowe, E., …Bahl, A. (in press). A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder. Clinical Genitourinary Cancer, https://doi.org/10.1016/j.clgc.2021.02.001

Introduction: Neoadjuvant cisplatin-based combination chemotherapy improves survival in muscle-invasive bladder cancer. However, response rates and survival remain suboptimal. We evaluated the efficacy, safety, and tolerability of cisplatin plus caba... Read More about A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder.

Fixed bearing, all-polyethylene tibia, lateral unicompartmental arthroplasty – A final outcome study with up to 28 year follow-up of a single implant (2021)
Journal Article
Porteous, A. J., Robinson, J. R., Smith, J. R., Murray, J. R., Bray, R., & White, P. (2021). Fixed bearing, all-polyethylene tibia, lateral unicompartmental arthroplasty – A final outcome study with up to 28 year follow-up of a single implant. Knee, 29, 101-109. https://doi.org/10.1016/j.knee.2020.12.032

Background: Lateral unicompartmental arthroplasty (UKA) constitutes only 5–10% of all unicompartmental replacements performed. Whilst the short and medium term benefits are well documented, there remains concern regarding the higher revision rate whe... Read More about Fixed bearing, all-polyethylene tibia, lateral unicompartmental arthroplasty – A final outcome study with up to 28 year follow-up of a single implant.

St Georg Sled medial unicompartmental arthroplasty: survivorship analysis and function at 20years follow up (2021)
Journal Article
Robinson, J. R., Murray, J. R., Smith, J. R., Porteous, A. J., Bray, R., & White, P. (in press). St Georg Sled medial unicompartmental arthroplasty: survivorship analysis and function at 20years follow up. Knee Surgery, Sports Traumatology, Arthroscopy, https://doi.org/10.1007/s00167-021-06454-6

Purpose: The peri-operative and short-term benefits of unicompartmental knee arthroplasty (UKA) are well supported in the literature. However, there remains concern regarding the higher revision rate when compared with total knee replacement. This ma... Read More about St Georg Sled medial unicompartmental arthroplasty: survivorship analysis and function at 20years follow up.

Differential expression of the BCAT isoforms between breast cancer subtypes (2020)
Journal Article
Shafei, M. A., Flemban, A., Daly, C., Kendrick, P., White, P., Dean, S., …Conway, M. E. (in press). Differential expression of the BCAT isoforms between breast cancer subtypes. Breast Cancer, https://doi.org/10.1007/s12282-020-01197-7

© 2020, The Author(s). Background: Biological characterisation of breast cancer subtypes is essential as it informs treatment regimens especially as different subtypes have distinct locoregional patterns. This is related to metabolic phenotype, where... Read More about Differential expression of the BCAT isoforms between breast cancer subtypes.

‘Everybody’s Different: The Appearance Game’. A randomised controlled trial evaluating an appearance-related board game intervention with children aged 9-11 years (2020)
Journal Article
Jarman, H., Guest, E., Hannah, J., Sharratt, N., Williamson, H., White, P., …Slater, A. (2021). ‘Everybody’s Different: The Appearance Game’. A randomised controlled trial evaluating an appearance-related board game intervention with children aged 9-11 years. Body Image, 36, 34-44. https://doi.org/10.1016/j.bodyim.2020.09.010

This study evaluated the effectiveness of an educational board game aimed at increasing knowledge of appearance-related issues, positive body image, media literacy, and acceptance of appearance diversity with British school children. Two hundred and... Read More about ‘Everybody’s Different: The Appearance Game’. A randomised controlled trial evaluating an appearance-related board game intervention with children aged 9-11 years.

A structured approach to evaluating life course hypotheses: Moving beyond analyses of exposed versus unexposed in the omics context (2020)
Journal Article
Zhu, Y., Simpkin, A. J., Suderman, M. J., Lussier, A. A., Walton, E., Dunn, E. C., & Smith, A. D. A. C. (2021). A structured approach to evaluating life course hypotheses: Moving beyond analyses of exposed versus unexposed in the omics context. American Journal of Epidemiology, 190(6), 1101-1112. https://doi.org/10.1093/aje/kwaa246

The structured life course modeling approach (SLCMA) is a theory-driven analytic method that empirically compares multiple prespecified life course hypotheses characterizing time-dependent exposure-outcome relationships to determine which theory best... Read More about A structured approach to evaluating life course hypotheses: Moving beyond analyses of exposed versus unexposed in the omics context.

Exposure to early childhood maltreatment and its effect over time on social cognition (2020)
Journal Article
Crawford, K. M., Choi, K., Davis, K. A., Zhu, Y., Soare, T. W., Smith, A. D., …Dunn, E. C. (in press). Exposure to early childhood maltreatment and its effect over time on social cognition. Development and Psychopathology, https://doi.org/10.1017/s095457942000139x

Social cognitive deficits can have many negative consequences, spanning social withdrawal to psychopathology. Prior work has shown that child maltreatment may associate with poorer social cognitive skills in later life. However, no studies have exami... Read More about Exposure to early childhood maltreatment and its effect over time on social cognition.

Daily medical liaison is associated with reduced length of stay and complications in selected patients admitted to a regional vascular surgery service (2020)
Journal Article
Mitchell, E., Coary, R., White, P., Farrow, E., Crees, A., Beedham, W., …Shipway, D. (2020). Daily medical liaison is associated with reduced length of stay and complications in selected patients admitted to a regional vascular surgery service. Geriatrics, 5(4), https://doi.org/10.3390/geriatrics5040078

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Older adults undergoing vascular surgery are particularly vulnerable to adverse outcomes by virtue of their vascular risk factors and medical comorbidities. This study aimed to determine the i... Read More about Daily medical liaison is associated with reduced length of stay and complications in selected patients admitted to a regional vascular surgery service.

Exact solutions and equi-dosing regimen regions for multi-dose pharmacokinetics models with transit compartments (2020)
Journal Article
Hof, F., & Bridge, L. J. (2021). Exact solutions and equi-dosing regimen regions for multi-dose pharmacokinetics models with transit compartments. Journal of Pharmacokinetics and Pharmacodynamics, 48, 99-131. https://doi.org/10.1007/s10928-020-09719-8

Compartmental models which yield linear ordinary differential equations (ODEs) provide common tools for pharmacokinetics (PK) analysis, with exact solutions for drug levels or concentrations readily obtainable for low-dimensional compartment models.... Read More about Exact solutions and equi-dosing regimen regions for multi-dose pharmacokinetics models with transit compartments.

How many words make a sample? Determining the minimum number of word tokens needed in connected speech samples for child speech assessment (2020)
Journal Article
Wren, Y., Titterington, J., & White, P. (in press). How many words make a sample? Determining the minimum number of word tokens needed in connected speech samples for child speech assessment. Clinical Linguistics & Phonetics, https://doi.org/10.1080/02699206.2020.1827458

Connected speech (CS) is an important component of child speech assessment in both clinical practice and research. There is debate in the literature regarding what size sample of CS is required to facilitate reliable measures of speech output. The ai... Read More about How many words make a sample? Determining the minimum number of word tokens needed in connected speech samples for child speech assessment.

Parent-reported socioemotional and cognitive development in children with a cleft lip and/or palate at 18 months: Findings from a UK birth cohort (2020)
Journal Article
Costa, B., White, P., Kiff, J. D., Davies, A., & Stock, N. M. (2021). Parent-reported socioemotional and cognitive development in children with a cleft lip and/or palate at 18 months: Findings from a UK birth cohort. Child: Care, Health and Development, 47(1), 31-39. https://doi.org/10.1111/cch.12813

Background: One of the most common congenital conditions in the world, cleft lip and/or palate (CL/P) has been shown to potentially impact long-term physical and developmental outcomes in affected children. However, little is known about the factors... Read More about Parent-reported socioemotional and cognitive development in children with a cleft lip and/or palate at 18 months: Findings from a UK birth cohort.

The development and validation of the Threat of Dementia Scale (2020)
Journal Article
Cheston, R., Dodd, E., Christopher, G., White, P., Wildschut, T., & Sedikides, C. (in press). The development and validation of the Threat of Dementia Scale. International Journal of Aging and Human Development, https://doi.org/10.1177/0091415020957388

Dementia represents a substantial threat to the self. However, to date, there is no reliable way to measure how threatened people feel by dementia. This article reports on two online studies. In Study 1, 248 participants rated statements about dement... Read More about The development and validation of the Threat of Dementia Scale.