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Modern Applications of Graph Theory (2021)
Book
Zverovich, V. (2021). Modern Applications of Graph Theory. Oxford, UK: Oxford University Press

This book discusses many modern, cutting-edge applications of graph theory, such as traffic networks, navigable networks and optimal routing for emergency response, placement of electric vehicle charging stations and graph-theoretic methods in comput... Read More about Modern Applications of Graph Theory.

A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder (2021)
Journal Article
Challapalli, A., Susan Masson, S., White, P., Dailami, N., Pearson, S., Rowe, E., …Bahl, A. (in press). A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder. Clinical Genitourinary Cancer, https://doi.org/10.1016/j.clgc.2021.02.001

Background: Neoadjuvant cisplatin-based combination chemotherapy improves survival in muscle invasive bladder cancer (MIBC). However, response rates and survival remain suboptimal. We sought to evaluate the efficacy, safety and tolerability of cisp... Read More about A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder.

Advanced molecular characterization using Digital Spatial Profiling Technology on immuno-oncology targets in methylated compared with unmethylated IDH-wildtype glioblastoma (2021)
Journal Article
Barber, H., Tofias, A., Lander, B., Daniels, A., Gong, J., Ren, Y., …Kurian, K. (in press). Advanced molecular characterization using Digital Spatial Profiling Technology on immuno-oncology targets in methylated compared with unmethylated IDH-wildtype glioblastoma. Journal of Oncology,

Introduction: Glioblastoma (GBM) is the most common primary adult brain tumour with a median overall survival (OS) of 12-15 months. Molecular characterization of multiple immuno-oncology targets in GBM may help target novel immunotherapeutic strategi... Read More about Advanced molecular characterization using Digital Spatial Profiling Technology on immuno-oncology targets in methylated compared with unmethylated IDH-wildtype glioblastoma.

St Georg Sled medial unicompartmental arthroplasty; survivorship analysis and function at 20 years follow-up (2021)
Journal Article
Porteous, A., Smith, J., Bray, R., Robinson, J., White, P., & Murray, J. (in press). St Georg Sled medial unicompartmental arthroplasty; survivorship analysis and function at 20 years follow-up. Knee Surgery, Sports Traumatology, Arthroscopy,

Purpose: The peri-operative and short term benefits of unicompartmental knee arthroplasty (UKA) are well supported in the literature. However, there remains concern regarding the higher revision rate when compared with total knee... Read More about St Georg Sled medial unicompartmental arthroplasty; survivorship analysis and function at 20 years follow-up.

Fixed bearing, all-polyethylene 4bia, lateral unicompartmental arthroplasty - a final out-come study with up to 28 year follow-up of a single implant (2020)
Journal Article
Murray, J., Smith, J., Bray, R., Robinson, J., White, P., & Porteous, A. (in press). Fixed bearing, all-polyethylene 4bia, lateral unicompartmental arthroplasty - a final out-come study with up to 28 year follow-up of a single implant. Knee,

Background: Lateral unicompartmental arthroplasty (UKA) constitutes only 5-10% of all unicompartmental replacements performed. Whilst the short and medium term benefits are well documented, there remains concern regarding the higher revision rate wh... Read More about Fixed bearing, all-polyethylene 4bia, lateral unicompartmental arthroplasty - a final out-come study with up to 28 year follow-up of a single implant.

Differential expression of the BCAT isoforms between breast cancer subtypes (2020)
Journal Article
Shafei, M. A., Flemban, A., Daly, C., Kendrick, P., White, P., Dean, S., …Conway, M. E. (in press). Differential expression of the BCAT isoforms between breast cancer subtypes. Breast Cancer, https://doi.org/10.1007/s12282-020-01197-7

© 2020, The Author(s). Background: Biological characterisation of breast cancer subtypes is essential as it informs treatment regimens especially as different subtypes have distinct locoregional patterns. This is related to metabolic phenotype, where... Read More about Differential expression of the BCAT isoforms between breast cancer subtypes.

A case study in the e-assessment of statistics for non-specialists (2020)
Journal Article
Weir, I. S., Gwynllyw, D. R., & Henderson, K. L. (in press). A case study in the e-assessment of statistics for non-specialists. Journal of University Teaching and Learning Practice,

The need to be able to choose, perform and interpret the results from appropriate statistical tests is ubiquitous in many STEM disciplines and beyond. In this case study, we illustrate a learning and assessment approach that has been used successfull... Read More about A case study in the e-assessment of statistics for non-specialists.

‘Everybody’s Different: The Appearance Game’. A randomised controlled trial evaluating an appearance-related board game intervention with children aged 9-11 years (2020)
Journal Article
Jarman, H., Guest, E., Hannah, J., Sharratt, N., Williamson, H., White, P., …Slater, A. (2021). ‘Everybody’s Different: The Appearance Game’. A randomised controlled trial evaluating an appearance-related board game intervention with children aged 9-11 years. Body Image, 36, 34-44. https://doi.org/10.1016/j.bodyim.2020.09.010

This study evaluated the effectiveness of an educational board game aimed at increasing knowledge of appearance-related issues, positive body image, media literacy, and acceptance of appearance diversity with British school children. Two hundred and... Read More about ‘Everybody’s Different: The Appearance Game’. A randomised controlled trial evaluating an appearance-related board game intervention with children aged 9-11 years.

A structured approach to evaluating life course hypotheses: Moving beyond analyses of exposed versus unexposed in the omics context (2020)
Journal Article
Zhu, Y., Simpkin, A. J., Suderman, M. J., Lussier, A. A., Walton, E., Dunn, E. C., & Smith, A. D. A. C. (in press). A structured approach to evaluating life course hypotheses: Moving beyond analyses of exposed versus unexposed in the omics context. American Journal of Epidemiology, https://doi.org/10.1093/aje/kwaa246

The structured life course modeling approach (SLCMA) is a theory-driven analytic method that empirically compares multiple prespecified life course hypotheses characterizing time-dependent exposure-outcome relationships to determine which theory best... Read More about A structured approach to evaluating life course hypotheses: Moving beyond analyses of exposed versus unexposed in the omics context.

Daily medical liaison is associated with reduced length of stay and complications in selected patients admitted to a regional vascular surgery service (2020)
Journal Article
Mitchell, E., Coary, R., White, P., Farrow, E., Crees, A., Beedham, W., …Shipway, D. (2020). Daily medical liaison is associated with reduced length of stay and complications in selected patients admitted to a regional vascular surgery service. Geriatrics, 5(4), https://doi.org/10.3390/geriatrics5040078

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Older adults undergoing vascular surgery are particularly vulnerable to adverse outcomes by virtue of their vascular risk factors and medical comorbidities. This study aimed to determine the i... Read More about Daily medical liaison is associated with reduced length of stay and complications in selected patients admitted to a regional vascular surgery service.

Exact solutions and equi-dosing regimen regions for multi-dose pharmacokinetics models with transit compartments (2020)
Journal Article
Hof, F., & Bridge, L. J. (in press). Exact solutions and equi-dosing regimen regions for multi-dose pharmacokinetics models with transit compartments. Journal of Pharmacokinetics and Pharmacodynamics, https://doi.org/10.1007/s10928-020-09719-8

Compartmental models which yield linear ordinary differential equations (ODEs) provide common tools for pharmacokinetics (PK) analysis, with exact solutions for drug levels or concentrations readily obtainable for low-dimensional compartment models.... Read More about Exact solutions and equi-dosing regimen regions for multi-dose pharmacokinetics models with transit compartments.

How many words make a sample? Determining the minimum number of word tokens needed in connected speech samples for child speech assessment (2020)
Journal Article
Wren, Y., Titterington, J., & White, P. (in press). How many words make a sample? Determining the minimum number of word tokens needed in connected speech samples for child speech assessment. Clinical Linguistics & Phonetics, https://doi.org/10.1080/02699206.2020.1827458

Connected speech (CS) is an important component of child speech assessment in both clinical practice and research. There is debate in the literature regarding what size sample of CS is required to facilitate reliable measures of speech output. The ai... Read More about How many words make a sample? Determining the minimum number of word tokens needed in connected speech samples for child speech assessment.

Parent-reported socioemotional and cognitive development in children with a cleft lip and/or palate at 18 months: Findings from a UK birth cohort (2020)
Journal Article
Costa, B., White, P., Kiff, J. D., Davies, A., & Stock, N. M. (2021). Parent-reported socioemotional and cognitive development in children with a cleft lip and/or palate at 18 months: Findings from a UK birth cohort. Child: Care, Health and Development, 47(1), 31-39. https://doi.org/10.1111/cch.12813

Background: One of the most common congenital conditions in the world, cleft lip and/or palate (CL/P) has been shown to potentially impact long-term physical and developmental outcomes in affected children. However, little is known about the factors... Read More about Parent-reported socioemotional and cognitive development in children with a cleft lip and/or palate at 18 months: Findings from a UK birth cohort.

The development and validation of the Threat of Dementia Scale (2020)
Journal Article
Cheston, R., Dodd, E., Christopher, G., White, P., Wildschut, T., & Sedikides, C. (in press). The development and validation of the Threat of Dementia Scale. International Journal of Aging and Human Development, https://doi.org/10.1177/0091415020957388

Dementia represents a substantial threat to the self. However, to date, there is no reliable way to measure how threatened people feel by dementia. This article reports on two online studies. In Study 1, 248 participants rated statements about dement... Read More about The development and validation of the Threat of Dementia Scale.

Factors associated with advanced colorectal cancer differ between young and older adults in England: A population-based cohort study (2020)
Journal Article
Chambers, A. C., Dixon, S. W., White, P., Thomas, M. G., Williams, A. C., & Messenger, D. E. (2020). Factors associated with advanced colorectal cancer differ between young and older adults in England: A population-based cohort study. Colorectal Disease, 22(12), 2087-2097. https://doi.org/10.1111/codi.15361

Aim: Advanced stage presentation of colorectal cancer is associated with poorer survival outcomes, particularly among young adults. This study aimed to determine whether demographic risk factors for advanced stage presentation differed between young... Read More about Factors associated with advanced colorectal cancer differ between young and older adults in England: A population-based cohort study.

Illicit drug contamination of the Bristol Pound local currency (2020)
Journal Article
Bowdler, P., Gale, E., Bryant, F., Codd, S., Hudd, S., Longden, R., …Honeychurch, K. C. (2020). Illicit drug contamination of the Bristol Pound local currency. Forensic Science International, 316, https://doi.org/10.1016/j.forsciint.2020.110469

Reports have shown the prevalence of the contamination of banknotes with a number of different drugs. These studies have focused on investigating drug contamination levels on currency which is either nationally or even international distributed. To p... Read More about Illicit drug contamination of the Bristol Pound local currency.

Analyzing kinetic signaling data for G-protein-coupled receptors (2020)
Journal Article
Hoare, S. R. J., Tewson, P. H., Quinn, A. M., Hughes, T. E., & Bridge, L. J. (2020). Analyzing kinetic signaling data for G-protein-coupled receptors. Scientific Reports, 10, https://doi.org/10.1038/s41598-020-67844-3

In classical pharmacology, bioassay data are fit to general equations (e.g. the dose response equation) to determine empirical drug parameters (e.g. EC50 and Emax), which are then used to calculate chemical parameters such as affinity and efficacy. H... Read More about Analyzing kinetic signaling data for G-protein-coupled receptors.

Case study using Python in the teaching of numerical analysis (2020)
Journal Article
Gwynllyw, D. R., Henderson, K. L., Van lent, J., & Guillot, E. G. (2020). Case study using Python in the teaching of numerical analysis. MSOR Connections, 18(2), 25-32. https://doi.org/10.21100/msor.v18i2.1100

In this case study we describe the rationale, methodology and results of teaching Python as part of a third year optional Numerical Analysis module taken by undergraduate BSc Mathematics students at the University of the West of England, Bristol. In... Read More about Case study using Python in the teaching of numerical analysis.