A comparison of European eel Anguilla anguilla eDNA concentrations to fyke net catches in five Irish lakes (2020)
Journal Article
Weldon, L., O’Leary, C., Steer, M., Newton, L., Macdonald, H., & Sargeant, S. L. (2020). A comparison of European eel Anguilla anguilla eDNA concentrations to fyke net catches in five Irish lakes. Environmental DNA, 2(4), 587-600. https://doi.org/10.1002/edn3.91

The European eel, Anguilla anguilla, is classified as critically endangered by the IUCN. To protect what remains of the European eel population, accurate monitoring methods for this species are important. Environmental DNA (eDNA) techniques are gaini... Read More about A comparison of European eel Anguilla anguilla eDNA concentrations to fyke net catches in five Irish lakes.

Regulating the regulator: nitric oxide control of post-translational modifications (2020)
Journal Article
Gupta, K. J., Kolbert, Z., Durner, J., Lindermayr, C., Corpas, F. J., Brouquisse, R., …Loake, G. J. (2020). Regulating the regulator: nitric oxide control of post-translational modifications. New Phytologist, 227(5), 1319-1325. https://doi.org/10.1111/nph.16622

Nitric oxide (NO) is perfectly suited for the role of a redox signalling molecule. A key route for NO bioactivity occurs via protein S-nitrosation, and involves the addition of a NO moiety to a protein cysteine (Cys) thiol (–SH) to form an S-nitrosot... Read More about Regulating the regulator: nitric oxide control of post-translational modifications.

Screen-printed carbon based biosensors and their applications in agri-food safety (2020)
Journal Article
Smart, A., Crew, A., Pemberton, R., Hughes, G., Doran, O., & Hart, J. P. (2020). Screen-printed carbon based biosensors and their applications in agri-food safety. Trends in Analytical Chemistry, 127, Article 115898. https://doi.org/10.1016/j.trac.2020.115898

This review focuses on the ways in which screen-printed carbon electrodes have been tailored with different biorecognition elements, including enzymes, antibodies, and aptamers, often with other modifiers, such as mediators and nanoparticles, to prod... Read More about Screen-printed carbon based biosensors and their applications in agri-food safety.

A grain rot of rice in Iran caused by a Xanthomonas strain closely related to X. sacchari (2020)
Journal Article
Mirghasempour, S. A., Huang, S., Studholme, D. J., & Brady, C. L. (2020). A grain rot of rice in Iran caused by a Xanthomonas strain closely related to X. sacchari. Plant Disease, 104(6), 1581-1583. https://doi.org/10.1094/PDIS-01-20-0179-SC

Rice grain rot disease was detected for the first time in Mazandaran Province, Iran. The bacteria isolated from infected rice plants showed grains rotted and darkening. A Xanthomonas strain closely connected to X. sacchari was identified using molecu... Read More about A grain rot of rice in Iran caused by a Xanthomonas strain closely related to X. sacchari.

Development of a facile fluorophosphonate-functionalised titanium surface for potential orthopaedic applications (2020)
Journal Article
Shiel, A. I., Ayre, W. N., Blom, A. W., Hallam, K. R., Heard, P. J., Payton, O., …Mansell, J. P. (2020). Development of a facile fluorophosphonate-functionalised titanium surface for potential orthopaedic applications. Journal of Orthopaedic Translation, 23, 140-151. https://doi.org/10.1016/j.jot.2020.02.002

Background: Aseptic loosening of total joint replacements (TJRs) continues to be the main cause of implant failures. The socioeconomic impact of surgical revisions is hugely significant; in the United Kingdom alone, it is estimated that £137 m is spe... Read More about Development of a facile fluorophosphonate-functionalised titanium surface for potential orthopaedic applications.

In vitro modelling of tongue derived microbial biofilms and their reponse to treatment (2020)
Thesis
Hewett, K. E. In vitro modelling of tongue derived microbial biofilms and their reponse to treatment. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/1491292

This work concerns the development of a flat plate perfusion model to study biofilms derived from human tongue biota. The model has been derived from a previous sorbarod model, via a flat plate model (used to study wound organisms), to the model desc... Read More about In vitro modelling of tongue derived microbial biofilms and their reponse to treatment.

Targeting the splice factor kinase CLK1 in prostate cancer cells (2020)
Thesis
Uzor, S. O. Targeting the splice factor kinase CLK1 in prostate cancer cells. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/1490733

Prostate cancer is the most rampant diagnosed cancer and the second leading cause of cancer related death in men between middle age and old age. There is a need to identify the molecular genetic processes that underpin prostate cancer and to search f... Read More about Targeting the splice factor kinase CLK1 in prostate cancer cells.

Antimicrobial activity of essential oils as liquid and vapour applications (2020)
Thesis
Elcocks, E. R. (2020). Antimicrobial activity of essential oils as liquid and vapour applications. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/1490727

Essential oils produced by plants have been used as antimicrobial agents historically, however, many essential oils remain under-exploited as alternatives to antimicrobials. Therefore, the aim of this thesis was to evaluate the antibacterial efficacy... Read More about Antimicrobial activity of essential oils as liquid and vapour applications.

ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia? (2020)
Journal Article
Vahabi, B., Jabr, R., Fry, C., McCloskey, K., Everaert, K., Agudelo, C. W., …Weiss, J. P. (2020). ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia?. Neurourology and Urodynamics, 39(S3 Supplement: ICI‐RS 2019), S88-S95. https://doi.org/10.1002/nau.24274

Introduction: The following is a report on the proceedings of the 2019 International Consultation on Incontinence-Research Society nocturia think tank (NTT). Objectives: The objectives of the 2019 NTT were as follows: (a) to evaluate the role of urot... Read More about ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia?.

Sensitivity to experiencing alcohol hangovers: Reconsideration of the 0.11% blood alcohol concentration (BAC) threshold for having a hangover (2020)
Journal Article
Verster, J. C., Kruisselbrink, L. D., Slot, K. A., Anogeianaki, A., Adams, S., Alford, C., …Stock, A. K. (2020). Sensitivity to experiencing alcohol hangovers: Reconsideration of the 0.11% blood alcohol concentration (BAC) threshold for having a hangover. Journal of Clinical Medicine, 9(1), Article 179. https://doi.org/10.3390/jcm9010179

The 2010 Alcohol Hangover Research Group consensus paper defined a cutoff blood alcohol concentration (BAC) of 0.11% as a toxicological threshold indicating that sufficient alcohol had been consumed to develop a hangover. The cutoff was based on prev... Read More about Sensitivity to experiencing alcohol hangovers: Reconsideration of the 0.11% blood alcohol concentration (BAC) threshold for having a hangover.

APC and AXIN2 are promising biomarker candidates for the early detection of adenomas and hyperplastic polyps (2020)
Journal Article
Almond, S., Anaraki, F., Young, C., Ashrafian Bonab, M., Asadzadeh-Aghdaei, H., Rezvani, H., …Ladomery, M. (2020). APC and AXIN2 are promising biomarker candidates for the early detection of adenomas and hyperplastic polyps. Cancer Informatics, 19, 1-8. https://doi.org/10.1177/1176935120972383

Aberrant activation of the WNT/CTNNB1 pathway is notorious in colorectal cancer (CRC). Here, we demonstrate that the expression of specific and crucial WNT signaling pathway genes is linked to disease progression in colonic adenomatous (AP) and hyper... Read More about APC and AXIN2 are promising biomarker candidates for the early detection of adenomas and hyperplastic polyps.

Polydopamine-lysophosphatidate-functionalised titanium: A novel hybrid surface finish for bone regenerative applications (2020)
Journal Article
Baldwin, F., Craig, T. J., Shiel, A. I., Cox, T., Lee, K., & Mansell, J. P. (2020). Polydopamine-lysophosphatidate-functionalised titanium: A novel hybrid surface finish for bone regenerative applications. Molecules, 25(7), Article 1583. https://doi.org/10.3390/molecules25071583

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Aseptic loo... Read More about Polydopamine-lysophosphatidate-functionalised titanium: A novel hybrid surface finish for bone regenerative applications.

The use of storm fragments and biodegradable replanting methods allows for a low-impact habitat restoration method of seagrass meadows, in the eastern Aegean Sea (2020)
Journal Article
Ward, E., Meek, S., Gordon, D., Cameron, T., Steer, M., Smith, D., …Tsimpidis, T. (2020). The use of storm fragments and biodegradable replanting methods allows for a low-impact habitat restoration method of seagrass meadows, in the eastern Aegean Sea. Conservation Evidence, 17, 1-16

Seagrasses are important marine ecosystems but are vulnerable to physical damage from anthropogenic activities such as anchoring and trawling. Replanting damaged areas can represent a viable restoration strategy, yet current methods rely on the remov... Read More about The use of storm fragments and biodegradable replanting methods allows for a low-impact habitat restoration method of seagrass meadows, in the eastern Aegean Sea.

Relationship between alcohol hangover and physical endurance performance: Walking the Samaria Gorge (2019)
Journal Article
Verster, J. C., Anogeianaki, A., Kruisselbrink, D., Alford, C., & Stock, A. K. (2020). Relationship between alcohol hangover and physical endurance performance: Walking the Samaria Gorge. Journal of Clinical Medicine, 9(1), Article 114. https://doi.org/10.3390/jcm9010114

Alcohol hangover is a potentially debilitating state. Several studies have demonstrated that it does not seem to impair strength or short-term endurance, but its effects on continuous exercise performance/long-term endurance have never been investiga... Read More about Relationship between alcohol hangover and physical endurance performance: Walking the Samaria Gorge.

Forensic science in Ghana: A review (2019)
Journal Article
Amankwaa, A. O., Nsiah Amoako, E., Mensah Bonsu, D. O., & Banyeh, M. (2019). Forensic science in Ghana: A review. Forensic Science International, 1, 151-160. https://doi.org/10.1016/j.fsisyn.2019.07.008

The use of forensic science continues to grow across the world. In Ghana, major advancements took off in 2011, including the introduction of modern DNA profiling and the establishment of an automated fingerprint identification system. These developme... Read More about Forensic science in Ghana: A review.

Leukaemic and bone marrow stromal cells alter cytarabine genotoxicity and cytotoxicity in favour of disease (2019)
Journal Article
May, J., Gynn, L., Anderson, E., & Robinson, G. (2019). Leukaemic and bone marrow stromal cells alter cytarabine genotoxicity and cytotoxicity in favour of disease. Mutagenesis, 34(5/6), e5. https://doi.org/10.1093/mutage/gez025

Resistance to therapy remains one of the greatest challenges in the management of the blood and bone marrow (BM) disorder, acute myeloid leukaemia (AML). This study aimed to investigate how leukaemic and BM stromal cells contribute to altered chemo-s... Read More about Leukaemic and bone marrow stromal cells alter cytarabine genotoxicity and cytotoxicity in favour of disease.

Rapid bactericidal effect of cinnamon bark essential oil against Pseudomonas aeruginosa (2019)
Journal Article
Elcocks, E., Spencer‐Phillips, P., & Adukwu, E. (2020). Rapid bactericidal effect of cinnamon bark essential oil against Pseudomonas aeruginosa. Journal of Applied Microbiology, 128(4), 1025-1037. https://doi.org/10.1111/jam.14538

AIMS: This study aimed to identify the most effective antimicrobial from a selection of essential oils and investigate its bactericidal properties against Ps. aeruginosa. METHODS AND RESULTS: The disc diffusion assay and minimal inhibitory/bacte... Read More about Rapid bactericidal effect of cinnamon bark essential oil against Pseudomonas aeruginosa.

Advantages and limitations of naturalistic study designs and their implementation in alcohol hangover research (2019)
Journal Article
Verster, J. C., van de Loo, A. J. A. E., Adams, S., Stock, A., Benson, S., Scholey, A., …Bruce, G. (2019). Advantages and limitations of naturalistic study designs and their implementation in alcohol hangover research. Journal of Clinical Medicine, 8(12), Article 2160. https://doi.org/10.3390/jcm8122160

In alcohol hangover research, both naturalistic designs and randomized controlled trials (RCTs) are successfully employed to study the causes, consequences, and treatments of hangovers. Although increasingly applied in both social sciences and medica... Read More about Advantages and limitations of naturalistic study designs and their implementation in alcohol hangover research.

Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML). (2019)
Journal Article
Gynn, L. E., Anderson, E., Robinson, G. M., Wexler, S. A., Upstill-Goddard, G., Cox, C., …Morgan, R. G. (2019). Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML). Blood, 134(Supplement 1), 2492. https://doi.org/10.1182/blood-2019-122891

Mesenchymal stromal cells (MSC) are known to protect leukemic cells from drug-induced toxicity within the bone marrow (BM) niche, however, less is known about leukemic impact on supportive MSC. The nucleoside-analogue, cytarabine (Ara-C), is a front-... Read More about Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML)..

Novel, rapid, low-cost screen-printed (bio)sensors for the direct analysis of boar taint compounds androstenone and skatole in porcine adipose tissue: Comparison with a high-resolution gas chromatographic method (2019)
Journal Article
Westmacott, K. L., Crew, A. P., Doran, O., & Hart, J. P. (2020). Novel, rapid, low-cost screen-printed (bio)sensors for the direct analysis of boar taint compounds androstenone and skatole in porcine adipose tissue: Comparison with a high-resolution gas chromatographic method. Biosensors and Bioelectronics, 150, Article 111837. https://doi.org/10.1016/j.bios.2019.111837

© 2019 Elsevier B.V. This is the first report on the fabrication, characterisation and application of an electrochemical (bio)sensor system for the simultaneous measurement of skatole and androstenone. A biosensor for androstenone was fabricated usin... Read More about Novel, rapid, low-cost screen-printed (bio)sensors for the direct analysis of boar taint compounds androstenone and skatole in porcine adipose tissue: Comparison with a high-resolution gas chromatographic method.