Use of illness severity scores to predict mortality in interstitial lung disease patients hospitalised with acute respiratory deterioration (2023)
Journal Article
Williams, R. L., Hyams, C., Robertshaw, J., Garcia Gonzalez, M., Szasz-Benczur, Z., White, P., … Barratt, S. L. (2023). Use of illness severity scores to predict mortality in interstitial lung disease patients hospitalised with acute respiratory deterioration. Respiratory Medicine, 212, 107220. https://doi.org/10.1016/j.rmed.2023.107220

Introduction: Hospitalisations relating to acute respiratory deteriorations (ARD) in Interstitial Lung Disease (ILD) have poor outcomes. Factors predicting adverse outcomes are not fully understood and data addressing the use of illness severity scor... Read More about Use of illness severity scores to predict mortality in interstitial lung disease patients hospitalised with acute respiratory deterioration.

Developing concept system for robotics open heart surgery (2022)
Digital Artefact
Farzadnia, F., D’Agnano, F., & Jorgensen, T. (in press). Developing concept system for robotics open heart surgery. [Website article]

Research interests in the healthcare field have for some time been growing within CFPR. A connection with Dr Muhammad Bilal from UWE’s Big Data Enterprise and Artificial Intelligence Lab is, in particular, developing some promising healthcare researc... Read More about Developing concept system for robotics open heart surgery.

Strengthening management, community engagement, and sustainability of the subnational response to accelerate malaria elimination in Namibia (2022)
Journal Article
Chung, A. M., Love, E., Neidel, J., Mendai, I., Nairenge, S., van Wyk, L. A., …Gosling, R. (2022). Strengthening management, community engagement, and sustainability of the subnational response to accelerate malaria elimination in Namibia. American Journal of Tropical Medicine and Hygiene, 106(6), 1646-1652. https://doi.org/10.4269/ajtmh.21-1195

Leadership and management skills are critical for health programs to deliver high-quality interventions in complex systems. In malaria-eliminating countries, national and subnational health teams are reorienting strategies to address focal transmissi... Read More about Strengthening management, community engagement, and sustainability of the subnational response to accelerate malaria elimination in Namibia.

An on-premise study to investigate the effects of mixing alcohol with caffeinated beverages (2022)
Journal Article
Johnson, S. J., Verster, J. C., & Alford, C. (2022). An on-premise study to investigate the effects of mixing alcohol with caffeinated beverages. Brain and Behavior, 12(3), Article e2445. https://doi.org/10.1002/brb3.2445

Objective: The purpose of this on-premise study was to determine if mixing alcohol with caffeinated mixers had an impact on objective and subjective intoxication. Methods: The study was conducted across eight drinking occasions in the City of Bristol... Read More about An on-premise study to investigate the effects of mixing alcohol with caffeinated beverages.

Early determinants of mortality in hospitalized COVID-19 patients in the Eastern Province of Saudi Arabia (2022)
Journal Article
Ansari, K. A., Alwazzeh, M. J., Alkuwaiti, F. A., Farooqi, F. A., Al Khathlan, N., Almutawah, H., …Alkuwaiti, E. (2022). Early determinants of mortality in hospitalized COVID-19 patients in the Eastern Province of Saudi Arabia. International Journal of General Medicine, 15(15), 1689-1701. https://doi.org/10.2147/ijgm.s349598

Purpose: This study investigated the clinical determinants of mortality in hospitalized patients infected with COVID-19. Patients and Methods: A retrospective multicenter large cohort of COVID-19 patients hospitalized between March 2020 and February... Read More about Early determinants of mortality in hospitalized COVID-19 patients in the Eastern Province of Saudi Arabia.

Automatic report-based labelling of clinical EEGs for classifier training (2022)
Conference Proceeding
Western, D., Weber, T., Kandasamy, R., May, F., Taylor, S., Zhu, Y., & Canham, L. (2022). Automatic report-based labelling of clinical EEGs for classifier training. In 2021 IEEE Signal Processing in Medicine and Biology Symposium (SPMB). https://doi.org/10.1109/SPMB52430.2021.9672295

Machine learning classifiers for detection of abnormal clinical electroencephalography (EEG) signals have advanced signficantly in recent years, largely supported by the carefully curated Temple University Hospital Abnormal EEG Corpus (TUAB). Further... Read More about Automatic report-based labelling of clinical EEGs for classifier training.

A comparison between ecological momentary assessment and the adapted-quick drinking screen: Alcohol mixed with energy drinks (2022)
Journal Article
Johnson, S. J., Verster, J. C., & Alford, C. (2022). A comparison between ecological momentary assessment and the adapted-quick drinking screen: Alcohol mixed with energy drinks. Alcohol and Alcoholism, 57(5), 630-640. https://doi.org/10.1093/alcalc/agab086

AIMS: To compare alcohol consumption and risk-taking behaviours on alcohol mixed with energy drink (AMED) and alcohol-only (AO) drinking occasions collected via ecological momentary assessment (EMA) versus retrospective survey methods (adapted-Quick... Read More about A comparison between ecological momentary assessment and the adapted-quick drinking screen: Alcohol mixed with energy drinks.

Accelerometers-embedded Lycra sleeves to test wear compliance and upper limb activity in people with stroke: A feasibility study (2021)
Journal Article
Kumar, P., Brodie, S., Molton, J., O'Reilly, R., Steele, J., Pearce, A., …Caleb-Solly, P. (2023). Accelerometers-embedded Lycra sleeves to test wear compliance and upper limb activity in people with stroke: A feasibility study. Journal of Prosthetics and Orthotics, 35(2), 122-128. https://doi.org/10.1097/JPO.0000000000000406

Introduction To establish a possible effect of Lycra sleeves, accurate recording of wear time is critical. The aim of this study was to test whether an accelerometer-embedded Lycra sleeve can measure wear compliance and record upper-limb (UL) movemen... Read More about Accelerometers-embedded Lycra sleeves to test wear compliance and upper limb activity in people with stroke: A feasibility study.

Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected (2021)
Journal Article
Gynn, L. E., Anderson, E., Robinson, G., Wexler, S. A., Upstill-Goddard, G., Cox, C., & May, J. E. (2021). Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected. Mutagenesis, 36(6), 419-428. https://doi.org/10.1093/mutage/geab033

Tumour microenvironments are hallmarked in many cancer types. In haematological malignancies, bone marrow (BM) mesenchymal stromal cells (MSC) protect malignant cells from drug-induced cytotoxicity. However, less is known about malignant impact on su... Read More about Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected.

How do illness perceptions influence the effectiveness of self-management in individuals living in Bermuda with type 2 diabetes? (2021)
Thesis
Matthew, T. How do illness perceptions influence the effectiveness of self-management in individuals living in Bermuda with type 2 diabetes?. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/7212112

Diabetes is a chronic condition that occurs when blood glucose, or blood sugar, levels are too high in the body (NHS, 2016). Diabetes UK (2009) estimates that self-management is 95% of managing diabetes. Self-management refers to an individual’s abil... Read More about How do illness perceptions influence the effectiveness of self-management in individuals living in Bermuda with type 2 diabetes?.

Propofol detection for monitoring of intravenous anaesthesia: A review (2021)
Journal Article
Ferrier, D., Kiely, J., & Luxton, R. (2022). Propofol detection for monitoring of intravenous anaesthesia: A review. Journal of Clinical Monitoring and Computing, 36, 315-323. https://doi.org/10.1007/s10877-021-00738-5

This paper presents a review of established and emerging methods for detecting and quantifying the intravenous anaesthetic propofol in solution. There is growing evidence of numerous advantages of total intravenous anaesthesia using propofol compared... Read More about Propofol detection for monitoring of intravenous anaesthesia: A review.

Data-driven approach to COVID-19 infection forecast for Nigeria using negative binomial regression model (2021)
Book Chapter
Olisah, C. C., Ilori, O. O., Adelaja, K., Usip, P. U., Uzoechi, L. O., Adeyanju, I. A., & Odumuyiwa, V. T. (2021). Data-driven approach to COVID-19 infection forecast for Nigeria using negative binomial regression model. In Data Science for COVID-19 (583-596). Elsevier. https://doi.org/10.1016/b978-0-12-824536-1.00002-2

COVID-19: the new wave of a global pandemic, is bringing about an increasing number of scientific efforts aimed at enabling governments to make informed decisions. In this paper, we explore the negative binomial regression model from the family of ge... Read More about Data-driven approach to COVID-19 infection forecast for Nigeria using negative binomial regression model.

Exploration of the possible role of microRNA(s) and small extracellular vesicles in chemotherapy-induced bystander effects (2021)
Thesis
Ude, A. Exploration of the possible role of microRNA(s) and small extracellular vesicles in chemotherapy-induced bystander effects. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/6971684

Advances in modern chemotherapeutic regimens have led to an increase in the overall survival of leukaemia patients in recent years. However, haematopoietic stem cell transplantation (HSCT) remains the curative option for these patients. In HSCT, high... Read More about Exploration of the possible role of microRNA(s) and small extracellular vesicles in chemotherapy-induced bystander effects.

Visual illusions modulate body perception disturbance and pain in Complex Regional Pain Syndrome: A randomized trial (2021)
Journal Article
Lewis, J. S., Newport, R., Taylor, G., Smith, M., & McCabe, C. S. (2021). Visual illusions modulate body perception disturbance and pain in Complex Regional Pain Syndrome: A randomized trial. European Journal of Pain, 25(7), 1551-1563. https://doi.org/10.1002/ejp.1766

Background: Effective treatment of longstanding Complex Regional Pain Syndrome (CRPS) is a challenge, as causal mechanisms remain elusive. People with CRPS frequently report distorted subjective perceptions of their affected limb. Evidence of pain re... Read More about Visual illusions modulate body perception disturbance and pain in Complex Regional Pain Syndrome: A randomized trial.

Patient reported outcomes in large vessel vasculitides (2021)
Journal Article
Robson, J., Mackie, S., & Hill, C. (2021). Patient reported outcomes in large vessel vasculitides. Current Rheumatology Reports, 23(2), Article 7. https://doi.org/10.1007/s11926-020-00979-4

Purpose of Review: The goal of this paper is to review current and future uses of patient-reported outcomes in large vessel vasculitis. The large vessel vasculitides comprise Giant Cell Arteritis and Takayasu arteritis; both are types of systemic vas... Read More about Patient reported outcomes in large vessel vasculitides.

A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer (2020)
Journal Article
Nounu, A., Greenhough, A., Heesom, K. J., Richmond, R. C., Zheng, J., Weinstein, S. J., …Relton, C. L. (2021). A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer. Cancer Epidemiology, Biomarkers and Prevention, 30(3), 564-575. https://doi.org/10.1158/1055-9965.EPI-20-1176

Background: Evidence for aspirin’s chemopreventative properties on colorectal cancer (CRC) is substantial, but its mechanism of action is not well-understood. We combined a proteomic approach with Mendelian randomization (MR) to identify possible new... Read More about A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer.

Novel method for the measurement of erythrocyte acetylcholinesterase activity in the Yt blood group system using amperometry in conjunction with screen-printed carbon electrodes (2020)
Journal Article
Crew, A., Karamatic Crew, V., Bagelow, L., Walser, P., Thornton, N., & Hart, J. (2020). Novel method for the measurement of erythrocyte acetylcholinesterase activity in the Yt blood group system using amperometry in conjunction with screen-printed carbon electrodes. Vox Sanguinis, 115(S1), 271-271. https://doi.org/10.1111/vox.13031

Background: The five antigens of the Yt blood group system are located on the membrane GPI‐linked erythrocyte acetylcholinesterase (AChE‐E), which is implicated in a range of clinical issues, including sleep apnoea and neurotoxin poisoning. Conformat... Read More about Novel method for the measurement of erythrocyte acetylcholinesterase activity in the Yt blood group system using amperometry in conjunction with screen-printed carbon electrodes.

The use of tissue adhesive as an adjunct to wound closure in knee arthroplasty does not reduce wound ooze (2020)
Journal Article
Khalefa, M. A., Smith, L. K., & Ahmad, R. (2020). The use of tissue adhesive as an adjunct to wound closure in knee arthroplasty does not reduce wound ooze. Knee Surgery & Related Research, 32(1), Article 57. https://doi.org/10.1186/s43019-020-00073-0

Introduction Persistent wound ooze has been associated with prolonged length of hospital stay and increased risk of infection. Recently, the use of tissue adhesive after hip and knee arthroplasty has been described. We believe that knee arthroplasty... Read More about The use of tissue adhesive as an adjunct to wound closure in knee arthroplasty does not reduce wound ooze.

Daily medical liaison is associated with reduced length of stay and complications in selected patients admitted to a regional vascular surgery service (2020)
Journal Article
Mitchell, E., Coary, R., White, P., Farrow, E., Crees, A., Beedham, W., …Shipway, D. (2020). Daily medical liaison is associated with reduced length of stay and complications in selected patients admitted to a regional vascular surgery service. Geriatrics, 5(4), Article 78. https://doi.org/10.3390/geriatrics5040078

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Older adults undergoing vascular surgery are particularly vulnerable to adverse outcomes by virtue of their vascular risk factors and medical comorbidities. This study aimed to determine the i... Read More about Daily medical liaison is associated with reduced length of stay and complications in selected patients admitted to a regional vascular surgery service.

Laboratory evaluation of the Sigma Transwab® transport system for the recovery of Candida species using the Clinical and Laboratory Standards Institute (CLSI) document M40-A2 (2020)
Journal Article
Adukwu, E., & Elcocks, E. (2021). Laboratory evaluation of the Sigma Transwab® transport system for the recovery of Candida species using the Clinical and Laboratory Standards Institute (CLSI) document M40-A2. European Journal of Clinical Microbiology and Infectious Diseases, 40, 735-738. https://doi.org/10.1007/s10096-020-04062-9

Rising healthcare complications due to fungal infections increase the importance of efficient specimen collection and maintenance systems for correct identification and diagnosis. The CLSI M40-A2 protocol provides guidelines for laboratories assessin... Read More about Laboratory evaluation of the Sigma Transwab® transport system for the recovery of Candida species using the Clinical and Laboratory Standards Institute (CLSI) document M40-A2.