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The relationship between type, timing and duration of exposure to adverse childhood experiences and adolescent self-harm and depression: Findings from three UK prospective population-based cohorts (2024)
Journal Article
Farooq, B., Russell, A., Howe, L., Herbert, A., Smith, A., Fisher, H., …Mars, B. (in press). The relationship between type, timing and duration of exposure to adverse childhood experiences and adolescent self-harm and depression: Findings from three UK prospective population-based cohorts. Journal of Child Psychology and Psychiatry, https://doi.org/10.1111/jcpp.13986

Background Adverse childhood experiences (ACEs) are well-established risk factors for self-harm and depression. However, despite their high comorbidity, there has been little focus on the impact of developmental timing and the duration of exposure t... Read More about The relationship between type, timing and duration of exposure to adverse childhood experiences and adolescent self-harm and depression: Findings from three UK prospective population-based cohorts.

Depressive symptoms in adolescence and adult educational and employment outcomes: A structured life course analysis (2024)
Journal Article
López-López, J., Tilling, K., Pearson, R., Fazel, M., Washbrook, E., Zhu, Y., …Smith, A. (in press). Depressive symptoms in adolescence and adult educational and employment outcomes: A structured life course analysis. Psychological Medicine,

Depression is a common mental health disorder which often starts during adolescence, with potentially important future consequences including ‘Not in Education, Employment or Training’ (NEET) status. In this study, we took a structured life course mo... Read More about Depressive symptoms in adolescence and adult educational and employment outcomes: A structured life course analysis.

Project-based learning integrated with e-Assessment (2024)
Journal Article
Derrick, B., & Weir, I. (2024). Project-based learning integrated with e-Assessment. MSOR Connections, 22(2), 12-20. https://doi.org/10.21100/msor.v22i2

This paper explores a recent move towards project-based learning for a first-year undergraduate statistics module at the University of the West of England, Bristol. The course is aimed at students specialising in Mathematics and Statistics. A classro... Read More about Project-based learning integrated with e-Assessment.

Computational modelling of dynamic cAMP responses to GPCR agonists for exploration of GLP-1R ligand effects in pancreatic β-cells and neurons (2024)
Journal Article
Bridge, L., Chen, S., & Jones, B. (2024). Computational modelling of dynamic cAMP responses to GPCR agonists for exploration of GLP-1R ligand effects in pancreatic β-cells and neurons. Cellular Signalling, Article 111153. https://doi.org/10.1016/j.cellsig.2024.111153

The glucagon-like peptide-1 receptor (GLP-1R) is a class B G protein-coupled receptor (GPCR) which plays important physiological roles in insulin release and promoting fullness. GLP-1R agonists initiate cellular responses by cyclic AMP (cAMP) pathway... Read More about Computational modelling of dynamic cAMP responses to GPCR agonists for exploration of GLP-1R ligand effects in pancreatic β-cells and neurons.

Diagnosing and remediating mathematical common student errors in e-assessment questions (A case study) (2024)
Presentation / Conference
Sikurajapathi, B., Henderson, K., & Gwynllyw, R. (2024, March). Diagnosing and remediating mathematical common student errors in e-assessment questions (A case study). Presented at Mathematics Education Seminar Series, University of Bristol

Mistakes and misconceptions in mathematics are as prevalent as those in any real-life situation. The errors frequently made by myriad students, known as Common Student Errors (CSEs), heavily influence their ability to learn and retain mathematics. Id... Read More about Diagnosing and remediating mathematical common student errors in e-assessment questions (A case study).

The inadvertently revealing statistic: A systemic gap in statistical training? (2024)
Journal Article
Derrick, B., Green, E., Ritchie, F., Smith, J., & White, P. (2024). The inadvertently revealing statistic: A systemic gap in statistical training?. Significance, 21(1), 24-27. https://doi.org/10.1093/jrssig/qmae009

While concerns around data privacy are well-known, there's a lack of awareness and training when it comes to the confidentiality risk of published statistics, argue Ben Derrick, Elizabeth Green, Felix Ritchie, Jim Smith, Paul White

Explainable NLP model for predicting patient admissions at emergency department using triage notes (2024)
Conference Proceeding
Arnaud, E., Elbattah, M., Moreno-Sánchez, P. A., Dequen, G., & Ghazali, D. A. (2024). Explainable NLP model for predicting patient admissions at emergency department using triage notes. In 2023 IEEE International Conference on Big Data (BigData) (4843-4847). https://doi.org/10.1109/bigdata59044.2023.10386753

Explainable Artificial Intelligence (XAI) has the potential to revolutionize healthcare by providing more transparent, trustworthy, and understandable predictions made by AI models. To this end, the present study aims to develop an explainable NLP mo... Read More about Explainable NLP model for predicting patient admissions at emergency department using triage notes.

The incidence of physician-diagnosed food allergy declines with age: A specialist UK centre experience (2023)
Journal Article
Grammatikos, A., Moghaddas, F., White, P., Fox, C., Johnston, S., Tsiougkos, N., & Gompels, M. (2024). The incidence of physician-diagnosed food allergy declines with age: A specialist UK centre experience. Clinical and Experimental Allergy, 54(2), 143-144. https://doi.org/10.1111/cea.14405

The incidence of physician-diagnosed food allergy declined with age in a cohort of UK adults. Men were more likely to be diagnosed with food allergy than women. The incidence of shellfish, wheat & cereals and vegetable & herb allergies increase... Read More about The incidence of physician-diagnosed food allergy declines with age: A specialist UK centre experience.

Long-term patient-reported outcomes of immediate breast reconstruction after mastectomy for breast cancer: Population-based cohort study (2023)
Journal Article
Johnson, L., White, P., Jeevan, R., Browne, J., Gulliver-Clarke, C., O’Donoghue, J., …Potter, S. (2023). Long-term patient-reported outcomes of immediate breast reconstruction after mastectomy for breast cancer: Population-based cohort study. British Journal of Surgery, 110(12), 1815-1823. https://doi.org/10.1093/bjs/znad276

BACKGROUND: Breast reconstruction is offered to improve quality of life for women after mastectomy for breast cancer, but information regarding the long-term patient-reported outcomes of different reconstruction procedures is currently lacking. The B... Read More about Long-term patient-reported outcomes of immediate breast reconstruction after mastectomy for breast cancer: Population-based cohort study.

Maintenance automation using deep learning methods: A case study from the aerospace industry (2023)
Conference Proceeding
Mayhew, P. J., Ihshaish, H., Deza, I., & Del Amo, A. (2023). Maintenance automation using deep learning methods: A case study from the aerospace industry. In Artificial Neural Networks and Machine Learning – ICANN 2023 (295-307). https://doi.org/10.1007/978-3-031-44204-9_25

In this study, state-of-the-art AI models are employed to classify aerospace maintenance records into categories based on the fault descriptions of avionic components. The classification is performed using short natural language text descriptions pro... Read More about Maintenance automation using deep learning methods: A case study from the aerospace industry.

The OdonAssist inflatable device for assisted vaginal birth—the ASSIST II study (United Kingdom) (2023)
Journal Article
Hotton, E. J., Hotton, E. J., Bale, N., Rose, C., White, P., Wade, J., …Reading, I. (2024). The OdonAssist inflatable device for assisted vaginal birth—the ASSIST II study (United Kingdom). American Journal of Obstetrics and Gynecology, 230(3), https://doi.org/10.1016/j.ajog.2023.05.018

Background: Decreasing rates of assisted vaginal birth have been paralleled with increasing rates of cesarean deliveries over the last 40 years. The OdonAssist is a novel device for assisted vaginal birth. Iterative changes to clinical parameters, de... Read More about The OdonAssist inflatable device for assisted vaginal birth—the ASSIST II study (United Kingdom).

A prospective comparison of invasive and non‐invasive blood pressure in children undergoing cardiac catheterization (2023)
Journal Article
Beringer, R., Keith, A., Jones, E., Murphy, T., & White, P. (in press). A prospective comparison of invasive and non‐invasive blood pressure in children undergoing cardiac catheterization. Pediatric Anesthesia, 33(10), 816-822. https://doi.org/10.1111/pan.14723

Background: Blood pressure measurement is a standard of monitoring during general anesthesia. Invasive measurement is considered the gold standard but is less commonly used than non-invasive. Automated oscillometric blood pressure devices measure the... Read More about A prospective comparison of invasive and non‐invasive blood pressure in children undergoing cardiac catheterization.

Oncological outcomes after transanal total mesorectal excision for rectal cancer (2023)
Journal Article
Francis, N., Penna, M., Dritsas, S., Kinsey, H., Moran, B., Nicol, D., …Wynn, G. (2023). Oncological outcomes after transanal total mesorectal excision for rectal cancer. British Journal of Surgery, 110(12), 1614-1617. https://doi.org/10.1093/bjs/znad168

Transanal total mesorectal excision (TaTME) was developed to overcome the technical difficulties of a transabdominal minimal-access approach to resection of low rectal cancer1–4. TaTME was reported to be feasible and effective, with the potential adv... Read More about Oncological outcomes after transanal total mesorectal excision for rectal cancer.

Association between the timing of childhood adversity and epigenetic patterns across childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) prospective cohort (2023)
Journal Article
Lussier, A. A., Zhu, Y., Smith, B. J., Cerutti, J., Fisher, J., Melton, P., …Dunn, E. C. (2023). Association between the timing of childhood adversity and epigenetic patterns across childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) prospective cohort. Lancet Child and Adolescent Health, 7(8), 532-543. https://doi.org/10.1016/S2352-4642%2823%2900127-X

Background: Childhood adversity is a potent determinant of health across development and is associated with altered DNA methylation signatures, which might be more common in children exposed during sensitive periods in development. However, it remain... Read More about Association between the timing of childhood adversity and epigenetic patterns across childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) prospective cohort.

Early intravenous beta-blockade with esmolol in adults with severe traumatic brain injury (EBB-TBI): Protocol for a phase 2a intervention design study (2023)
Journal Article
Thomas, M., Hayes, K., White, P., Ramesh, A., Culliford, L., Ackland, G., & Pickering, A. (2024). Early intravenous beta-blockade with esmolol in adults with severe traumatic brain injury (EBB-TBI): Protocol for a phase 2a intervention design study. Neurocritical Care, 40, 795–806. https://doi.org/10.1007/s12028-023-01755-9

Traumatic brain injury is a leading cause of death and disability worldwide. Interventions that mitigate secondary brain injury have the potential to improve outcomes for patients and reduce the impact on communities and society. Increased circulatin... Read More about Early intravenous beta-blockade with esmolol in adults with severe traumatic brain injury (EBB-TBI): Protocol for a phase 2a intervention design study.

The just-about-right pilot sample size to control the error margin (2023)
Journal Article
Obodo, S., Toher, D., & White, P. (2023). The just-about-right pilot sample size to control the error margin. International Journal of Statistics and Probability, 12(3), https://doi.org/10.5539/ijsp.v12n3p1

In practice, the required sample size for a two-arm randomised controlled trial cannot always be determined pre-study with great accuracy. This lack of accuracy has economic, ethical and scientific implications. The sample size for a pilot study is... Read More about The just-about-right pilot sample size to control the error margin.

Insulin-like growth factor binding protein-2 and glucose-regulated protein 78 kDa: Potential biomarkers affect prognosis in IDH-wildtype glioblastoma patients (2023)
Journal Article
Harland, A. J., Perks, C. M., White, P., Kurian, K. M., & Barber, H. R. (2023). Insulin-like growth factor binding protein-2 and glucose-regulated protein 78 kDa: Potential biomarkers affect prognosis in IDH-wildtype glioblastoma patients. Cancer Medicine, 12(13), 14426-14439. https://doi.org/10.1002/cam4.6071

Background: The overall survival of IDH-wildtype glioblastoma patients is poor despite best available treatments. There is an urgent need for new biomarkers to inform more precise disease stratification. Previous studies have identified insulin-like... Read More about Insulin-like growth factor binding protein-2 and glucose-regulated protein 78 kDa: Potential biomarkers affect prognosis in IDH-wildtype glioblastoma patients.

Outcomes from a community speech and language therapy service treatment waiting list: The natural history of 525 children with identified speech and language needs (2023)
Journal Article
Hesketh, E., White, P., Simkiss, D., & Roulstone, S. (2023). Outcomes from a community speech and language therapy service treatment waiting list: The natural history of 525 children with identified speech and language needs. International Journal of Language and Communication Disorders, 58(5), 1510-1525. https://doi.org/10.1111/1460-6984.12877

Abstract Background Understanding the natural history of developmental speech and language impairments can support the selection of children whose difficulties are persistent rather than transitory. It can also provide information against which... Read More about Outcomes from a community speech and language therapy service treatment waiting list: The natural history of 525 children with identified speech and language needs.

The effect of isocaloric, energy-restrictive, KETOgenic diet on metabolism, inflammation, nutrition deficiencies and oxidative stress in women with overweight and obesity (KETO-MINOX): Study protocol (2023)
Journal Article
Drabinska, N., Romaszko, J., & White, P. (2023). The effect of isocaloric, energy-restrictive, KETOgenic diet on metabolism, inflammation, nutrition deficiencies and oxidative stress in women with overweight and obesity (KETO-MINOX): Study protocol. PLoS ONE, 18(5), Article e0285283. https://doi.org/10.1371/journal.pone.0285283

Obesity is considered one of the biggest health problems of the 21st century, becoming a worldwide epidemic, leading to the development of many diseases and increasing the risk of premature death. The first step in reducing body weight is a calorie-r... Read More about The effect of isocaloric, energy-restrictive, KETOgenic diet on metabolism, inflammation, nutrition deficiencies and oxidative stress in women with overweight and obesity (KETO-MINOX): Study protocol.

The randomised thoracoscopic talc poudrage+indwelling pleural catheters versus thoracoscopic talc poudrage only in malignant pleural effusion trial (TACTIC): Study protocol for a randomised controlled trial (2023)
Journal Article
Sundaralingam, A., Hedley, E., Tucker, E., White, P., Bhatnagar, R., Moore, A., …Maskell, N. A. (2023). The randomised thoracoscopic talc poudrage+indwelling pleural catheters versus thoracoscopic talc poudrage only in malignant pleural effusion trial (TACTIC): Study protocol for a randomised controlled trial. BMJ Open Respiratory Research, 10(1), e001682. https://doi.org/10.1136/bmjresp-2023-001682

INTRODUCTION: Malignant pleural effusion (MPE) is common, with 50 000 new cases per year in the UK. MPE causes disabling breathlessness and indicates advanced disease with a poor prognosis. Treatment approaches focus on symptom relief and optimising... Read More about The randomised thoracoscopic talc poudrage+indwelling pleural catheters versus thoracoscopic talc poudrage only in malignant pleural effusion trial (TACTIC): Study protocol for a randomised controlled trial.