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Mark Lyttle's Outputs (149)

Factors associated with repeat emergency department visits for mental health care in adolescents: A scoping review (2024)
Journal Article

1.1 Objectives
The aim of this review was to identify factors associated with multiple visits to emergency department (ED) services for mental health care in adolescents.
1.2 Methods
Electronic databases (MEDLINE, PsycINFO, Embase, CINAHL, Web of... Read More about Factors associated with repeat emergency department visits for mental health care in adolescents: A scoping review.

Which elements of hospital-based clinical decision support tools for the assessment and management of children with head injury can be adapted for use by paramedics in prehospital care? A systematic mapping review and narrative synthesis (2024)
Journal Article

Objective Hospital-based clinical decision tools support clinician decision-making when a child presents to the emergency department with a head injury, particularly regarding CT scanning. However, there is no decision tool to support prehospital cli... Read More about Which elements of hospital-based clinical decision support tools for the assessment and management of children with head injury can be adapted for use by paramedics in prehospital care? A systematic mapping review and narrative synthesis.

The clinical impact of serious respiratory disease in children under the age of two years during the 2021-2022 bronchiolitis season in England, Scotland and Ireland (2023)
Journal Article

Interventions introduced to reduce the spread of SARS-CoV-2 led to a widespread reduction in childhood infections. However, from spring 2021 onwards the United Kingdom and Ireland experienced an unusual out-of-season epidemic of respiratory disease.... Read More about The clinical impact of serious respiratory disease in children under the age of two years during the 2021-2022 bronchiolitis season in England, Scotland and Ireland.

Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: A qualitative study (2023)
Journal Article

Objective To identify the outcomes considered important, and factors influencing the patient experience, for parents and caregivers of children presenting to hospital with a severe acute exacerbation of asthma. This work contributes to the outcome-id... Read More about Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: A qualitative study.

Applying clinical decision aids for the assessment and management of febrile infants presenting to emergency care in the UK and Ireland: Febrile Infant Diagnostic Assessment and Outcome (FIDO) Study protocol (2023)
Journal Article

Introduction Febrile infants 90 days and younger are at risk of invasive bacterial infections (bacteraemia and meningitis) and urinary tract infections. Together this is previously termed serious bacterial infection with an incidence of approximately... Read More about Applying clinical decision aids for the assessment and management of febrile infants presenting to emergency care in the UK and Ireland: Febrile Infant Diagnostic Assessment and Outcome (FIDO) Study protocol.

A diagnostic accuracy study to evaluate standard rapid diagnostic test (RDT) alone to safely rule out imported malaria in children presenting to UK emergency departments (2023)
Journal Article

BACKGROUND: Microscopy is the gold standard for malaria diagnosis but is dependent on trained personnel. Rapid diagnostic tests (RDTs) form the mainstay of diagnosis in endemic areas without access to high-quality microscopy. We aimed to evaluate whe... Read More about A diagnostic accuracy study to evaluate standard rapid diagnostic test (RDT) alone to safely rule out imported malaria in children presenting to UK emergency departments.

Factors related to adverse long-term outcomes after mild traumatic brain injury in children: A scoping review (2023)
Journal Article

Objective: To identify demographic, premorbid and injury-related factors, or biomarkers associated with long-term (≥3 months) adverse outcomes in children after mild traumatic brain injury (mTBI). Design: Scoping review of literature. Patients: Child... Read More about Factors related to adverse long-term outcomes after mild traumatic brain injury in children: A scoping review.

International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: A qualitative interview study (2023)
Journal Article

Background: Acute exacerbations of asthma are common in children, however, treatment decisions for severe exacerbations are challenging due to a lack of robust evidence. In order to create more robust research, a core set of outcome measures needs to... Read More about International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: A qualitative interview study.

The journey back to normality: Support systems and posttrauma needs following exposure to single-incident trauma among children and adolescents (2023)
Journal Article

Social support has been linked to posttrauma adjustment in children and adolescents, but the components of good support remain poorly defined. We conducted qualitative interviews with 30 youths aged 7–16 years after being admitted to a hospital follo... Read More about The journey back to normality: Support systems and posttrauma needs following exposure to single-incident trauma among children and adolescents.

A systematic literature review of the relationship between parenting responses and child post-traumatic stress symptoms (2022)
Journal Article

Background: Parents are a key source of support for children exposed to single-incident/acute traumas and can thereby play a potentially significant role in children’s post-trauma psychological adjustment. However, the evidence base examining parenta... Read More about A systematic literature review of the relationship between parenting responses and child post-traumatic stress symptoms.

International variation in evidence-based emergency department management of bronchiolitis: a retrospective cohort study (2022)
Journal Article

OBJECTIVES: We aimed to evaluate the international variation in the use of evidence-based management (EBM) in bronchiolitis. We hypothesised that management consistent with full-EBM practices is associated with the research network of care, adjusted... Read More about International variation in evidence-based emergency department management of bronchiolitis: a retrospective cohort study.

Educational interventions to prevent paediatric abusive head trauma in babies younger than one year old: A systematic review and meta-analyses (2022)
Journal Article

Background: Paediatric abusive head trauma (AHT) occurs in young children due to violent shaking or blunt impact. Educational and behavioural programmes modifying parent/infant interactions may aid primary prevention. This systematic review aims to a... Read More about Educational interventions to prevent paediatric abusive head trauma in babies younger than one year old: A systematic review and meta-analyses.

Paediatric major incident triage: A Delphi process to determine clinicians' attitudes and beliefs within the United Kingdom and Ireland (2022)
Journal Article

Aim: Triage is key to effective management of major incidents, yet there is scarce evidence surrounding the optimal method of paediatric major incident triage (MIT). This study aimed to derive consensus on key components of paediatric MIT among healt... Read More about Paediatric major incident triage: A Delphi process to determine clinicians' attitudes and beliefs within the United Kingdom and Ireland.

Features of the transposed seasonality of the 2021 RSV epidemic in the UK and Ireland: analysis of the first 10 000 patients (2022)
Journal Article

Non-pharmaceutical interventions (NPIs) introduced globally to limit the spread of SARS-CoV-2 led to disruption of the typical respiratory syncytial virus (RSV) seasonality.1 Studies examining the resurgence of RSV have been limited by sample size an... Read More about Features of the transposed seasonality of the 2021 RSV epidemic in the UK and Ireland: analysis of the first 10 000 patients.

Presentations of children to emergency departments across Europe and the COVID-19 pandemic: A multinational observational study (2022)
Journal Article

BACKGROUND: During the initial phase of the Coronavirus Disease 2019 (COVID-19) pandemic, reduced numbers of acutely ill or injured children presented to emergency departments (EDs). Concerns were raised about the potential for delayed and more sever... Read More about Presentations of children to emergency departments across Europe and the COVID-19 pandemic: A multinational observational study.

Diagnostic test accuracy of dipstick urinalysis for diagnosing urinary tract infection in febrile infants attending the emergency department (2022)
Journal Article

OBJECTIVE: To report the diagnostic test accuracy of dipstick urinalysis for the detection of urinary tract infections (UTIs) in febrile infants aged 90 days or less attending the emergency department (ED). DESIGN: Retrospective cohort study. PATIENT... Read More about Diagnostic test accuracy of dipstick urinalysis for diagnosing urinary tract infection in febrile infants attending the emergency department.

Barriers to emergency department clinicians' confidence in providing paediatric trauma‐informed care (2022)
Journal Article

Background: It has been estimated that around 31% of children will experience a traumatic event during childhood, most commonly serious accidents that lead to hospitalisation. Around 15% of children who experience such events go onto develop post‐tra... Read More about Barriers to emergency department clinicians' confidence in providing paediatric trauma‐informed care.

Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: A PERUKI service evaluation (2022)
Journal Article

Background Management of acute pain should commence at the earliest opportunity, as it has many short-term and long-term consequences. A research priority of Paediatric Emergency Research in the UK and Ireland (PERUKI) was to examine paediatric pain... Read More about Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: A PERUKI service evaluation.

Validating clinical practice guidelines for the management of febrile infants presenting to the emergency department in the UK and Ireland (2022)
Journal Article

Objective To report the performance of clinical practice guidelines (CPG) in the diagnosis of serious/invasive bacterial infections (SBI/IBI) in infants presenting with a fever to emergency care in the UK and Ireland. Two CPGs were from the National... Read More about Validating clinical practice guidelines for the management of febrile infants presenting to the emergency department in the UK and Ireland.

Periorbital and orbital cellulitis in children: A survey of emergency physicians and analysis of clinical practice guidelines across the PERUKI network (2022)
Journal Article

Background: Due to limited evidence to guide management of periorbital cellulitis (POC), we surveyed current practice and assessed quality and consistency of local clinical practice guidelines (CPGs) to highlight future research priorities. Methods:... Read More about Periorbital and orbital cellulitis in children: A survey of emergency physicians and analysis of clinical practice guidelines across the PERUKI network.

Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop (2022)
Journal Article

Objectives The objective of this study was to develop a core outcome set (COS) for use in future clinical trials in bronchiolitis. We wanted to find out which outcomes are important to healthcare professionals (HCPs) and to parents and which outcomes... Read More about Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop.

Amoxicillin duration and dose for community-acquired pneumonia in children: the CAP-IT factorial non-inferiority RCT (2021)
Journal Article

Background: Data are limited regarding the optimal dose and duration of amoxicillin treatment for community-acquired pneumonia in children. Objectives: To determine the efficacy, safety and impact on antimicrobial resistance of shorter (3-day) and lo... Read More about Amoxicillin duration and dose for community-acquired pneumonia in children: the CAP-IT factorial non-inferiority RCT.

Effect of Amoxicillin dose and treatment duration on the need for antibiotic re-treatment in children with Community-Acquired Pneumonia: The CAP-IT randomized clinical trial (2021)
Journal Article

Importance: The optimal dose and duration of oral amoxicillin for children with community-acquired pneumonia (CAP) are unclear. Objective: To determine whether lower-dose amoxicillin is noninferior to higher dose and whether 3-day treatment is noninf... Read More about Effect of Amoxicillin dose and treatment duration on the need for antibiotic re-treatment in children with Community-Acquired Pneumonia: The CAP-IT randomized clinical trial.

Psychological distress during the acceleration phase of the COVID-19 pandemic: A survey of doctors practising in emergency medicine, anaesthesia and intensive care medicine in the UK and Ireland (2021)
Journal Article

Objective: To quantify psychological distress experienced by emergency, anaesthetic and intensive care doctors during the acceleration phase of COVID-19 in the UK and Ireland. Methods: Initial cross-sectional electronic survey distributed during acce... Read More about Psychological distress during the acceleration phase of the COVID-19 pandemic: A survey of doctors practising in emergency medicine, anaesthesia and intensive care medicine in the UK and Ireland.

A survey of mHealth use from a physician perspective in paediatric emergency care in the UK and Ireland (2021)
Journal Article

Abstract: There has been a drive towards increased digitalisation in healthcare. The aim was to provide a snapshot of current apps, instant messaging, and smartphone photography use in paediatric emergency care. A web-based self-report questionnaire... Read More about A survey of mHealth use from a physician perspective in paediatric emergency care in the UK and Ireland.

Ingestion of metallic foreign bodies: A Paediatric Emergency Research in the United Kingdom and Ireland survey of current practice and hand-held metal detector use (2021)
Journal Article

Aim: To describe variation in the initial management of children presenting to Emergency Departments (ED) with coins lodged in the oesophagus. To determine the usage of hand-held metal detectors (HHMDs) in EDs, including their role in clinical decisi... Read More about Ingestion of metallic foreign bodies: A Paediatric Emergency Research in the United Kingdom and Ireland survey of current practice and hand-held metal detector use.

Seroprevalence of SARS-CoV-2 antibodies in children of United Kingdom healthcare workers: A prospective multicentre cohort study protocol (2020)
Journal Article

Background:
A novel coronavirus SARS-CoV-2 has been responsible for a worldwide pandemic. Children typically have very mild, or no, symptoms of infection. This makes estimations of seroprevalence in children difficult. Research is therefore required... Read More about Seroprevalence of SARS-CoV-2 antibodies in children of United Kingdom healthcare workers: A prospective multicentre cohort study protocol.

Validating clinical practice guidelines for the management of children with non-blanching rashes in the UK (PiC): A prospective, multicentre cohort study (2020)
Journal Article

Background:
No previous studies have validated current clinical practice guidelines for the management of non-blanching rashes in children who have received meningococcal B and C vaccinations. The aim of this study was to evaluate the performance o... Read More about Validating clinical practice guidelines for the management of children with non-blanching rashes in the UK (PiC): A prospective, multicentre cohort study.

Diagnostic test accuracy of point-of-care procalcitonin to diagnose serious bacterial infections in children (2020)
Journal Article

Background: The National Institute for Health and Care Excellence (NICE) have called for research into the role of biomarkers, and specifically procalcitonin (PCT), for the early diagnosis of serious bacterial infections (SBI) in children. The aim of... Read More about Diagnostic test accuracy of point-of-care procalcitonin to diagnose serious bacterial infections in children.

Planning for success: Overcoming challenges to recruitment and conduct of an open-label emergency department-led paediatric trial (2020)
Journal Article

Background Key challenges to the successful conduct of The Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus in children (EcLiPSE) trial were identified at the pre-trial stage. These included practitioner anxieties about condu... Read More about Planning for success: Overcoming challenges to recruitment and conduct of an open-label emergency department-led paediatric trial.

Seven-step framework to enhance practitioner explanations and parental understandings of research without prior consent in paediatric emergency and critical care trials (2020)
Journal Article

Background: Alternatives to prospective informed consent enable the conduct of paediatric emergency and critical care trials. Research without prior consent (RWPC) involves practitioners approaching parents after an intervention has been given and se... Read More about Seven-step framework to enhance practitioner explanations and parental understandings of research without prior consent in paediatric emergency and critical care trials.

COVID-19 emergency response assessment study: a prospective longitudinal survey of frontline doctors in the UK and Ireland: study protocol (2020)
Journal Article

INTRODUCTION: The COVID-19 pandemic is putting an unprecedented strain on healthcare systems globally. The psychological impact on frontline doctors of dealing with the COVID-19 pandemic is currently unknown. This longitudinal professional survey aim... Read More about COVID-19 emergency response assessment study: a prospective longitudinal survey of frontline doctors in the UK and Ireland: study protocol.

Loop-mediated isothermal amplification for the early diagnosis of invasive meningococcal disease in children (2020)
Journal Article

Background Rapid molecular diagnostic testing has the potential to improve the early recognition of meningococcal disease (MD). The aim of this study was to report on the diagnostic test accuracy of point-of-care loop-mediated isothermal amplificatio... Read More about Loop-mediated isothermal amplification for the early diagnosis of invasive meningococcal disease in children.

Exposure and confidence with critical non-airway procedures: A global survey of paediatric emergency medicine physicians (2020)
Journal Article

Background:
Children rarely experience critical illness, resulting in low exposure of emergency physicians (EPs) to critical procedures. Our primary objective was to describe senior EP confidence, most recent performance and/or supervision of criti... Read More about Exposure and confidence with critical non-airway procedures: A global survey of paediatric emergency medicine physicians.

The effect of patient observation on cranial computed tomography rates in children with minor head trauma (2020)
Journal Article

Background
Management of children with minor blunt head trauma often includes a period of observation to determine the need for cranial computed tomography (CT). Our objective was to estimate the effect of planned observation on CT use for each Pedi... Read More about The effect of patient observation on cranial computed tomography rates in children with minor head trauma.

Acute severe paediatric asthma: Study protocol for the development of a core outcome set, a Pediatric Emergency Research Networks (PERN) study (2020)
Journal Article

Background
Acute severe childhood asthma is an infrequent, but potentially life-threatening emergency condition. There is a wide range of different approaches to this condition, with very little supporting evidence, leading to significant variation... Read More about Acute severe paediatric asthma: Study protocol for the development of a core outcome set, a Pediatric Emergency Research Networks (PERN) study.

Neonatal head injuries: A prospective Paediatric Research in Emergency Departments International Collaborative cohort study (2019)
Journal Article

Aim
To characterise the causes, clinical characteristics and short‐term outcomes of neonates who presented to paediatric emergency departments with a head injury.

Methods
Secondary analysis of a prospective data set of paediatric head injuries a... Read More about Neonatal head injuries: A prospective Paediatric Research in Emergency Departments International Collaborative cohort study.

Inhaled methoxyflurane (Penthrox®) versus placebo for injury-associated analgesia in children - The MAGPIE trial (MEOF-002): Study protocol for a randomised controlled trial (2019)
Journal Article

Background
Pain from injuries is one of the commonest symptoms in children attending emergency departments (EDs), and this is often inadequately treated in both the pre-hospital and ED settings, in part due to challenges of continual assessment and... Read More about Inhaled methoxyflurane (Penthrox®) versus placebo for injury-associated analgesia in children - The MAGPIE trial (MEOF-002): Study protocol for a randomised controlled trial.

Mobile device and app use in paediatric emergency care: A survey of departmental practice in the UK and Ireland (2019)
Journal Article

Introduction Mobile devices and medical apps are used by healthcare professionals in adult and paediatric emergency departments worldwide. Recently, there has been a drive toward increased digitalisation especially in the UK. This point prevalence su... Read More about Mobile device and app use in paediatric emergency care: A survey of departmental practice in the UK and Ireland.

Parents’ prioritised outcomes for trials investigating treatments for paediatric severe infection: A qualitative synthesis (2019)
Journal Article

Objective: To identify parents' prioritised outcomes by combining qualitative findings from two trial feasibility studies of interventions for paediatric suspected severe infection. Design: Qualitative synthesis combining parent interview data from t... Read More about Parents’ prioritised outcomes for trials investigating treatments for paediatric severe infection: A qualitative synthesis.

Pharmacotherapy in bronchiolitis at discharge from emergency departments within the Pediatric Emergency Research Networks: A retrospective analysis (2019)
Journal Article

Background
Clinical guidelines advise against pharmacotherapy in bronchiolitis. However, little is known about global variation in prescribing practices for bronchiolitis at discharge from emergency departments. We aimed to evaluate global variation... Read More about Pharmacotherapy in bronchiolitis at discharge from emergency departments within the Pediatric Emergency Research Networks: A retrospective analysis.

Parents' and clinicians' views on conducting paediatric diagnostic test accuracy studies without prior informed consent: Qualitative insight from the Petechiae in Children study (PiC) (2019)
Journal Article

Objective: The Petechiae in Children (PiC) study assesses the utility of presenting features and rapid diagnostic tests in the diagnosis of serious bacterial infection in feverish children with non-blanching rashes. An embedded qualitative study expl... Read More about Parents' and clinicians' views on conducting paediatric diagnostic test accuracy studies without prior informed consent: Qualitative insight from the Petechiae in Children study (PiC).

Efficacy, safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia: A protocol for a randomIsed controlled Trial (CAP-IT) (2019)
Journal Article

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ. Introduction Community-acquired pneumonia (CAP) is a common indication for antibiotic treatment in young children. Data are limited regarding the ideal dose and... Read More about Efficacy, safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia: A protocol for a randomIsed controlled Trial (CAP-IT).

Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial (2019)
Journal Article

Background
Phenytoin is the recommended second-line intravenous anticonvulsant for treatment of paediatric convulsive status epilepticus in the UK; however, some evidence suggests that levetiracetam could be an effective and safer alternative. This... Read More about Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial.

Enhancing practitioners’ confidence in recruitment and consent in the EcLiPSE trial: A mixed-method evaluation of site training – a Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study (2019)
Journal Article

Background: EcLiPSE (Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus in children) is a randomised controlled trial (RCT) in the United Kingdom. Challenges to success include the need to immediately administer an intervention... Read More about Enhancing practitioners’ confidence in recruitment and consent in the EcLiPSE trial: A mixed-method evaluation of site training – a Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study.

Paediatric intentional head injuries in the emergency department: A multicentre prospective cohort study (2018)
Journal Article

© 2018 Australasian College for Emergency Medicine Objective: Although there is a large body of research on head injury (HI) inflicted by caregivers in young children, little is known about intentional HI in older children and inflicted HI by perpetr... Read More about Paediatric intentional head injuries in the emergency department: A multicentre prospective cohort study.

A cost-effectiveness analysis comparing clinical decision rules PECARN, CATCH, and CHALICE with usual care for the management of pediatric head injury (2018)
Journal Article

© 2018 American College of Emergency Physicians Study objective: To determine the cost-effectiveness of 3 clinical decision rules in comparison to Australian and New Zealand usual care: the Children's Head Injury Algorithm for the Prediction of Impor... Read More about A cost-effectiveness analysis comparing clinical decision rules PECARN, CATCH, and CHALICE with usual care for the management of pediatric head injury.

Defining significant childhood illness and injury in the Emergency Department: A consensus of UK and Ireland expert opinion (2018)
Journal Article

© Author(s) (or their employer(s)) 2018. No commercial re-use. See rights and permissions. Published by BMJ. Background Clarifying whether paediatric early warning scores (PEWS) accurately predict significant illness is a research priority for UK and... Read More about Defining significant childhood illness and injury in the Emergency Department: A consensus of UK and Ireland expert opinion.

Preferred learning modalities and practice for critical skills: A global survey of paediatric emergency medicine clinicians (2018)
Journal Article

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ. Objective To describe senior paediatric emergency clinician perspectives on the optimal frequency of and preferred modalities for practising... Read More about Preferred learning modalities and practice for critical skills: A global survey of paediatric emergency medicine clinicians.

External validation of the Scandinavian guidelines for management of minimal, mild and moderate head injuries in children (2018)
Journal Article

© 2018 The Author(s). Background: Clinical decision rules (CDRs) aid in the management of children with traumatic brain injury (TBI). Recently, the Scandinavian Neurotrauma Committee (SNC) has published practical, evidence-based guidelines for childr... Read More about External validation of the Scandinavian guidelines for management of minimal, mild and moderate head injuries in children.

A Longitudinal Examination of the Relationship between Trauma-Related Cognitive Factors and Internalising and Externalising Psychopathology in Physically Injured Children (2018)
Journal Article

© 2018, The Author(s). Cognitive models of posttraumatic stress disorder (PTSD) highlight maladaptive posttrauma appraisals, trauma memory qualities, and coping strategies, such as rumination or thought suppression, as key processes that maintain PTS... Read More about A Longitudinal Examination of the Relationship between Trauma-Related Cognitive Factors and Internalising and Externalising Psychopathology in Physically Injured Children.

Paediatric traumatic cardiac arrest: The development of an algorithm to guide recognition, management and decisions to terminate resuscitation (2018)
Journal Article

© Author(s) (or their employer(s)) 2018. No commercial re-use. See rights and permissions. Published by BMJ. Introduction Paediatric traumatic cardiac arrest (TCA) is a high acuity, low frequency event. Traditionally, survival from TCA has been repor... Read More about Paediatric traumatic cardiac arrest: The development of an algorithm to guide recognition, management and decisions to terminate resuscitation.

The "Petechiae in children" (PiC) study: Evaluating potential clinical decision rules for the management of feverish children with non-blanching rashes, including the role of point of care testing for Procalcitonin & Neisseria meningitidis DNA - a study protocol (2018)
Journal Article

© 2018 The Author(s). Background: Children commonly present to Emergency Departments (ED) with a non-blanching rash in the context of a feverish illness. While most have a self-limiting viral illness, this combination of features potentially represen... Read More about The "Petechiae in children" (PiC) study: Evaluating potential clinical decision rules for the management of feverish children with non-blanching rashes, including the role of point of care testing for Procalcitonin & Neisseria meningitidis DNA - a study protocol.

Paediatric traumatic cardiac arrest: A Delphi study to establish consensus on definition and management (2018)
Journal Article

Aims Paediatric traumatic cardiac arrest (TCA) is associated with low survival and poor outcomes. The mechanisms that underlie TCA are different from medical cardiac arrest; the approach to treatment of TCA may therefore also need to differ to optimi... Read More about Paediatric traumatic cardiac arrest: A Delphi study to establish consensus on definition and management.

Penetrating head injuries in children presenting to the emergency department in Australia and New Zealand: A PREDICT prospective study (2018)
Journal Article

© 2018 Paediatrics and Child Health Division (The Royal Australasian College of Physicians) Aim: Penetrating head injuries (pHIs) are associated with high morbidity and mortality. Data on pHIs in children outside North America are limited. We describ... Read More about Penetrating head injuries in children presenting to the emergency department in Australia and New Zealand: A PREDICT prospective study.

Accuracy of Clinician Practice Compared With Three Head Injury Decision Rules in Children: A Prospective Cohort Study (2018)
Journal Article

© 2018 American College of Emergency Physicians Study objective: Three clinical decision rules for head injuries in children (Pediatric Emergency Care Applied Research Network [PECARN], Canadian Assessment of Tomography for Childhood Head Injury [CAT... Read More about Accuracy of Clinician Practice Compared With Three Head Injury Decision Rules in Children: A Prospective Cohort Study.

Knowledge and training in paediatric medical traumatic stress and trauma-informed care among emergency medical professionals in low- and middle-income countries (2018)
Journal Article

© 2018, © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Background: Provision of psychosocial care, in particular trauma-informed care, in the immediate aftermath of paediatric injury is a recommended strat... Read More about Knowledge and training in paediatric medical traumatic stress and trauma-informed care among emergency medical professionals in low- and middle-income countries.

51 Paediatric emergency clinicians are rarely exposed to non-airway critical procedures: a predict/PERN study (2017)
Journal Article

© 2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. BACKGROUND: Recent studies suggest that approximately one p... Read More about 51 Paediatric emergency clinicians are rarely exposed to non-airway critical procedures: a predict/PERN study.

Guidelines for the use of chest radiographs in community-acquired pneumonia in children and adolescents (2017)
Journal Article

© 2017, The Author(s). National guidance from the United Kingdom and the United States on community-acquired pneumonia in children states that chest radiographs are not recommended routinely in uncomplicated cases. The main reason in the ambulatory s... Read More about Guidelines for the use of chest radiographs in community-acquired pneumonia in children and adolescents.

A qualitative feasibility study to inform a randomised controlled trial of fluid bolus therapy in septic shock (2017)
Journal Article

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. Objective The Fluids in Shock (FiSh) Trial proposes to evaluate whether restrictive fluid bolus therapy (10 mL/ kg) is more benef... Read More about A qualitative feasibility study to inform a randomised controlled trial of fluid bolus therapy in septic shock.

Perspectives of hospital emergency department staff on trauma-informed care for injured children: An Australian and New Zealand analysis (2017)
Journal Article

© 2017 Paediatrics and Child Health Division (The Royal Australasian College of Physicians) Aim: To examine Australian and New Zealand emergency department (ED) staff's training, knowledge and confidence regarding trauma-informed care for children af... Read More about Perspectives of hospital emergency department staff on trauma-informed care for injured children: An Australian and New Zealand analysis.

Diagnostic accuracy of the NEXUS II head injury clinical decision rule in children. A PREDICT prospective cohort study (2017)
Journal Article

Aims Clinical decision rules (CDRs) can be applied in Emergency Departments (EDs) to optimise the use of computed tomography (CT) in children with head trauma. The National Emergency X- Radiography Utilisation Study II (NEXUS II) CDR, as amended for... Read More about Diagnostic accuracy of the NEXUS II head injury clinical decision rule in children. A PREDICT prospective cohort study.

Defining mild traumatic brain injury: How classification differs across studies when applied to a large prospective data set. A PREDICT prospective cohort study (2017)
Journal Article

Aims Mild traumatic brain injury (TBI) in children is a major public health issue, yet there is wide variation in the way ‘mild’ TBI is defined in the literature and in guidelines. To date no study has prospectively detailed the proportion of childre... Read More about Defining mild traumatic brain injury: How classification differs across studies when applied to a large prospective data set. A PREDICT prospective cohort study.

Confirmation of traumatic cardiac arrest in children: A literature review to inform the peruki ptca consensus study (2017)
Journal Article

Aims Traumatic cardiac arrest (TCA) is associated with high mortality and poor neurological outcomes. Several methods of confirming cardiac arrest are utilised including auscultation of heart sounds, palpation of pulses and echocardiography. We did a... Read More about Confirmation of traumatic cardiac arrest in children: A literature review to inform the peruki ptca consensus study.

Accuracy of physician practice as compared with PECARN, CATCH and CHALICE head injury clinical decision rules in children. A PREDICT prospective cohort study (2017)
Journal Article

Aims Clinical decision rules (CDRs) can assist in determining the need for computed tomography (CT) in children with head injuries (HIs). We assessed the accuracy of 3 high quality CDRs (PECARN, CATCH and CHALICE) in a large prospective cohort of hea... Read More about Accuracy of physician practice as compared with PECARN, CATCH and CHALICE head injury clinical decision rules in children. A PREDICT prospective cohort study.

Paediatric intentional head injuriesin the emergency department. A PREDICT multicentre prospective cohort study (2017)
Journal Article

Aims While the majority of head injuries (HIs) in children are non-intentional, there is limited information on intentional HIs outside abusive head trauma. The objective of this study was to describe epidemiology, demographics and severity of intent... Read More about Paediatric intentional head injuriesin the emergency department. A PREDICT multicentre prospective cohort study.

Paediatric traumatic cardiac arrest– A Delphi study to establish consensus on management. A PERUKI study (2017)
Journal Article

Background Paediatric traumatic cardiac arrest (TCA) is associated with low survival and poor outcomes. The mechanisms that underlie TCA are different from medical cardiac arrest; the approach to treatment of TCA may therefore also need to differ to... Read More about Paediatric traumatic cardiac arrest– A Delphi study to establish consensus on management. A PERUKI study.

Epidemiology and aetiology of paediatric traumatic cardiac arrest in england and wales, a peruki study (2017)
Journal Article

Background Traumatic cardiac arrest (TCA) in children has traditionally been described as having a poor outcome. Survival rates vary widely between studies with higher rates observed from mechanisms leading to a respiratory cause of TCA (e.g. drownin... Read More about Epidemiology and aetiology of paediatric traumatic cardiac arrest in england and wales, a peruki study.

Emergency treatment with levetiracetam or phenytoin in status epilepticus in children-the EcLiPSE study: Study protocol for a randomised controlled trial (2017)
Journal Article

© The Author(s). 2017. Background: Convulsive status epilepticus (CSE) is the most common life-threatening neurological emergency in childhood. These children are also at risk of significant morbidity, with acute and chronic impact on the family and... Read More about Emergency treatment with levetiracetam or phenytoin in status epilepticus in children-the EcLiPSE study: Study protocol for a randomised controlled trial.

A qualitative feasibility study to inform Fluids in Shock (FISH) - a pilot randomised controlled trial of fluid bolus therapy in septic shock (2016)
Journal Article

Objectives & Background
There is increasing evidence that fluid overload may be associated with harm in paediatric critical illness. Fluids in Shock (FiSH) is a combined feasibility and pilot randomised controlled trial (RCT) to determine if restric... Read More about A qualitative feasibility study to inform Fluids in Shock (FISH) - a pilot randomised controlled trial of fluid bolus therapy in septic shock.

Emergency department re-attendances and treatment modifications in young children with uncomplicated community-acquired pneumonia: A PERUKI study (2016)
Journal Article

Objectives & Background
Data on the rate of antibiotic retreatment in children with uncomplicated community-acquired pneumonia (CAP) are lacking. We conducted a service evaluation of CAP management to review assumptions for a large UK-based trial p... Read More about Emergency department re-attendances and treatment modifications in young children with uncomplicated community-acquired pneumonia: A PERUKI study.

The transition to clinical expert: Enhanced decision making for children aged less than 5years attending the paediatric ED with acute respiratory conditions (2016)
Journal Article

© Published by the BMJ Publishing Group Limited. Background Rates of unplanned paediatric admissions are persistently high. Many admissions are short-stay events, lasting less than 48 hours. Objective This qualitative research explores factors that i... Read More about The transition to clinical expert: Enhanced decision making for children aged less than 5years attending the paediatric ED with acute respiratory conditions.

A qualitative study of the barriers to procedural sedation practices in paediatric emergency medicine in the UK and Ireland (2016)
Journal Article

© Published by the BMJ Publishing Group Limited. Introduction There is extensive literature on paediatric procedural sedation (PPS) and its clinical applications in emergency departments (EDs). While numerous guidance and policy documents exist from... Read More about A qualitative study of the barriers to procedural sedation practices in paediatric emergency medicine in the UK and Ireland.

G255(P) Psychological interventions for patients of all ages with mild traumatic brain injury: A systematic review (2016)
Journal Article

Introduction Head injury is the commonest injury type in UK children accounting for 350,000 Emergency Department attendances every year. While many of these are trivial a significant proportion have a mild traumatic brain injury (mTBI) which is synon... Read More about G255(P) Psychological interventions for patients of all ages with mild traumatic brain injury: A systematic review.

G213 Handlebar Grip Related Injury Prevention (GRIP) feasibility study: Are exposed metal handlebar ends on children’s bikes and scooters a risk factor for serious injury? (2016)
Journal Article

Aims Handlebar-end impact is a well-recognised cause of major intra-abdominal injury in childhood. Through this feasibility study and the associated main study we aim to reduce the incidence and severity these injuries. Proper understanding of risk f... Read More about G213 Handlebar Grip Related Injury Prevention (GRIP) feasibility study: Are exposed metal handlebar ends on children’s bikes and scooters a risk factor for serious injury?.

Establishing the research priorities of paediatric emergency medicine clinicians in the UK and Ireland (2015)
Journal Article

Objective: Paediatric Emergency Research in the UK and Ireland (PERUKI) is a collaborative clinical studies group established in August 2012. It consists of a network of 43 centres from England, Ireland, Northern Ireland, Scotland and Wales, and aims... Read More about Establishing the research priorities of paediatric emergency medicine clinicians in the UK and Ireland.

The accuracy of existing prehospital triage tools for injured children in England: An analysis using emergency department data (2015)
Journal Article

Objective To investigate the performance characteristics in children with moderate and minor injuries of prehospital paediatric triage tools currently in use in England for identifying seriously injured children. Methods Eight prehospital paediatric... Read More about The accuracy of existing prehospital triage tools for injured children in England: An analysis using emergency department data.

Variation in treatment of acute childhood wheeze in emergency departments of the United Kingdom and Ireland: An international survey of clinician practice (2015)
Journal Article

© 2015, BMJ Publishing Group. All rights reserved. Objective: National clinical guidelines for childhood wheeze exist, yet despite being one of the most common reasons for childhood emergency department (ED) attendance, signi ficant variation in prac... Read More about Variation in treatment of acute childhood wheeze in emergency departments of the United Kingdom and Ireland: An international survey of clinician practice.

Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland? (2015)
Journal Article

During a prospective 10-week assessment period, 3238 children aged 1-16 years presented with acute wheeze to Paediatric Emergency Research in the UK and Ireland centres. 110 (3.3%) received intravenous bronchodilators. Intravenous magnesium sulfate (... Read More about Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland?.

A prospective observational study to assess the diagnostic accuracy of clinical decision rules for children presenting to emergency departments after head injuries (protocol): The Australasian Paediatric Head Injury Rules Study (APHIRST) (2014)
Journal Article

Background: Head injuries in children are responsible for a large number of emergency department visits. Failure to identify a clinically significant intracranial injury in a timely fashion may result in long term neurodisability and death. Whilst cr... Read More about A prospective observational study to assess the diagnostic accuracy of clinical decision rules for children presenting to emergency departments after head injuries (protocol): The Australasian Paediatric Head Injury Rules Study (APHIRST).

Applicability of the CATCH, CHALICE and PECARN paediatric head injury clinical decision rules: Pilot data from a single Australian centre (2013)
Journal Article

Background Clinical decision rules (CDRs) for paediatric head injury (HI) exist to identify children at risk of traumatic brain injury. Those of the highest quality are the Canadian assessment of tomography for childhood head injury (CATCH), Children... Read More about Applicability of the CATCH, CHALICE and PECARN paediatric head injury clinical decision rules: Pilot data from a single Australian centre.

Predictors of severe H1N1 infection in children presenting within Pediatric Emergency Research Networks (PERN): Retrospective case-control study (2013)
Journal Article

Objective To identify historical and clinical findings at emergency department presentation associated with severe H1N1 outcome in children presenting with influenza-like illness. Design Multicentre retrospective case-control study. Setting 79 emerge... Read More about Predictors of severe H1N1 infection in children presenting within Pediatric Emergency Research Networks (PERN): Retrospective case-control study.

The accuracy of existing prehospital triage tools for injured children in England - An analysis using trauma registry data (2013)
Journal Article

Objectives: To investigate the performance characteristics of prehospital paediatric triage tools for identifying seriously injured children in England. Design: Eight prehospital paediatric triage tools were identified by literature review and by sur... Read More about The accuracy of existing prehospital triage tools for injured children in England - An analysis using trauma registry data.

Survey of the use of therapeutic hypothermia after cardiac arrest in UK paediatric emergency departments (2013)
Journal Article

Objectives: To ascertain current use of therapeutic hypothermia (TH) after paediatric cardiac arrest in UK emergency departments (EDs), and views on participating in a UK randomised controlled trial (RCT) incorporating early induction of TH in ED. De... Read More about Survey of the use of therapeutic hypothermia after cardiac arrest in UK paediatric emergency departments.