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Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland?

Powell, Collin V.E.; Lyttle, M. D.; Morris, I.; Lyttle, Mark; O'Sullivan, R.; Sargant, N.; Doull, I. J.M.; Powell, C.V.E.

Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland? Thumbnail


Authors

Collin V.E. Powell

M. D. Lyttle

I. Morris

R. O'Sullivan

N. Sargant

I. J.M. Doull

C.V.E. Powell



Abstract

During a prospective 10-week assessment period, 3238 children aged 1-16 years presented with acute wheeze to Paediatric Emergency Research in the UK and Ireland centres. 110 (3.3%) received intravenous bronchodilators. Intravenous magnesium sulfate (MgSO4) was used in 67 (60.9%), salbutamol in 61 (55.5%) and aminophylline in 52 (47.3%) of cases. In 35 cases (31.8%), two drugs were used together, and in 18 cases (16.4%), all three drugs were administered. When used sequentially the most common order was salbutamol, then MgSO4, then aminophylline. Overall, 30 different intravenous treatment regimens were used varying in drugs, dose, rate and duration.

Citation

Powell, C. V., Lyttle, M. D., Morris, I., Lyttle, M., O'Sullivan, R., Sargant, N., …Powell, C. (2015). Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland?. Thorax, 70(1), 88-91. https://doi.org/10.1136/thoraxjnl-2014-206041

Journal Article Type Article
Publication Date Jan 1, 2015
Publicly Available Date Jun 6, 2019
Journal Thorax
Print ISSN 0040-6376
Electronic ISSN 1468-3296
Publisher BMJ Publishing Group
Peer Reviewed Peer Reviewed
Volume 70
Issue 1
Pages 88-91
DOI https://doi.org/10.1136/thoraxjnl-2014-206041
Keywords intravenous bronchodilators, children, acute severe wheeze, UK, Ireland
Public URL https://uwe-repository.worktribe.com/output/840258
Publisher URL http://dx.doi.org/10.1136/thoraxjnl-2014-206041
Additional Information Additional Information : Published Online First: 10 October 2014

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