Collin V.E. Powell
Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland?
Powell, Collin V.E.; Lyttle, M. D.; Morris, I.; Lyttle, Mark; O'Sullivan, R.; Sargant, N.; Doull, I. J.M.; Powell, C.V.E.
M. D. Lyttle
Mark Lyttle firstname.lastname@example.org
I. J.M. Doull
During a prospective 10-week assessment period, 3238 children aged 1-16 years presented with acute wheeze to Paediatric Emergency Research in the UK and Ireland centres. 110 (3.3%) received intravenous bronchodilators. Intravenous magnesium sulfate (MgSO4) was used in 67 (60.9%), salbutamol in 61 (55.5%) and aminophylline in 52 (47.3%) of cases. In 35 cases (31.8%), two drugs were used together, and in 18 cases (16.4%), all three drugs were administered. When used sequentially the most common order was salbutamol, then MgSO4, then aminophylline. Overall, 30 different intravenous treatment regimens were used varying in drugs, dose, rate and duration.
Powell, C. V., Lyttle, M. D., Morris, I., Lyttle, M., O'Sullivan, R., Sargant, N., …Powell, C. (2015). Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland?. Thorax, 70(1), 88-91. https://doi.org/10.1136/thoraxjnl-2014-206041
|Journal Article Type||Article|
|Publication Date||Jan 1, 2015|
|Publisher||BMJ Publishing Group|
|Peer Reviewed||Peer Reviewed|
|Keywords||intravenous bronchodilators, children, acute severe wheeze, UK, Ireland|
|Additional Information||Additional Information : Published Online First: 10 October 2014|
Childhoodwheeze_observedpractice_Thorax_Morris et al_UWErepository.pdf
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