Pharmacotherapy in bronchiolitis at discharge from emergency departments within the Pediatric Emergency Research Networks: A retrospective analysis

Jamal, Alisha; Finkelstein, Yaron; Kuppermann, Nathan; Freedman, Stephen B.; Florin, Todd A.; Babl, Franz E.; Dalziel, Stuart R.; Zemek, Roger; Plint, Amy C.; Steele, Dale W.; Schnadower, David; Johnson, David W.; Stephens, Derek; Kharbanda, Anupam; Roland, Damian; Lyttle, Mark D.; Macias, Charles G.; Fernandes, Ricardo M.; Benito, Javier; Schuh, Suzanne

doi:10.1016/s2352-4642(19)30193-2

Pharmacotherapy in bronchiolitis at discharge from emergency departments within the Pediatric Emergency Research Networks: A retrospective analysis

Jamal, Alisha; Finkelstein, Yaron; Kuppermann, Nathan; Freedman, Stephen B.; Florin, Todd A.; Babl, Franz E.; Dalziel, Stuart R.; Zemek, Roger; Plint, Amy C.; Steele, Dale W.; Schnadower, David; Johnson, David W.; Stephens, Derek; Kharbanda, Anupam; Roland, Damian; Lyttle, Mark D.; Macias, Charles G.; Fernandes, Ricardo M.; Benito, Javier; Schuh, Suzanne

Authors

Alisha Jamal

Yaron Finkelstein

Nathan Kuppermann

Stephen B. Freedman

Todd A. Florin

Franz E. Babl

Stuart R. Dalziel

Roger Zemek

Amy C. Plint

Dale W. Steele

David Schnadower

David W. Johnson

Derek Stephens

Anupam Kharbanda

Damian Roland

Mark Lyttle mark.lyttle@uwe.ac.uk

Charles G. Macias

Ricardo M. Fernandes

Javier Benito

Suzanne Schuh

Abstract

Background
Clinical guidelines advise against pharmacotherapy in bronchiolitis. However, little is known about global variation in prescribing practices for bronchiolitis at discharge from emergency departments. We aimed to evaluate global variation in prescribing practice (ie, inhaled salbutamol, or oral or inhaled corticosteroids) for infants with bronchiolitis at discharge from emergency departments.
Methods
We did a planned secondary analysis of a multinational, retrospective cohort study of the Pediatric Emergency Research Networks. Previously healthy infants (aged under 12 months) who were discharged with bronchiolitis between Jan 1 and Dec 31, 2013 from 38 emergency departments in Australia and New Zealand, Canada, Spain and Portugal, the UK and Ireland, and the USA were included. The primary outcome was pharmacotherapy prescription at discharge from the emergency department. Secondary outcomes were revisits to the emergency department or hospitalisations for bronchiolitis within 21 days of discharge.

Journal Article Type	Article
Acceptance Date	Mar 27, 2019
Online Publication Date	Jun 7, 2019
Publication Date	Aug 1, 2019
Deposit Date	Jul 20, 2020
Publicly Available Date	Jul 22, 2020
Journal	Lancet Child and Adolescent Health
Print ISSN	2352-4642
Electronic ISSN	2352-4642
Publisher	Elsevier
Peer Reviewed	Peer Reviewed
Volume	3
Issue	8
Pages	539-547
DOI	https://doi.org/10.1016/s2352-4642%2819%2930193-2
Public URL	https://uwe-repository.worktribe.com/output/6137354