Pharmacotherapy in bronchiolitis at discharge from emergency departments within the Pediatric Emergency Research Networks: A retrospective analysis

Jamal, Alisha; Finkelstein, Yaron; Kuppermann, Nathan; Freedman, Stephen B.; Florin, Todd A.; Babl, Franz E.; Dalziel, Stuart R.; Zemek, Roger; Plint, Amy C.; Steele, Dale W.; Schnadower, David; Johnson, David W.; Stephens, Derek; Kharbanda, Anupam; Roland, Damian; Lyttle, Mark D.; Macias, Charles G.; Fernandes, Ricardo M.; Benito, Javier; Schuh, Suzanne

Abstract

Background
Clinical guidelines advise against pharmacotherapy in bronchiolitis. However, little is known about global variation in prescribing practices for bronchiolitis at discharge from emergency departments. We aimed to evaluate global variation in prescribing practice (ie, inhaled salbutamol, or oral or inhaled corticosteroids) for infants with bronchiolitis at discharge from emergency departments.
Methods
We did a planned secondary analysis of a multinational, retrospective cohort study of the Pediatric Emergency Research Networks. Previously healthy infants (aged under 12 months) who were discharged with bronchiolitis between Jan 1 and Dec 31, 2013 from 38 emergency departments in Australia and New Zealand, Canada, Spain and Portugal, the UK and Ireland, and the USA were included. The primary outcome was pharmacotherapy prescription at discharge from the emergency department. Secondary outcomes were revisits to the emergency department or hospitalisations for bronchiolitis within 21 days of discharge.

Citation

Jamal, A., Finkelstein, Y., Kuppermann, N., Freedman, S. B., Florin, T. A., Babl, F. E., …Schuh, S. (2019). Pharmacotherapy in bronchiolitis at discharge from emergency departments within the Pediatric Emergency Research Networks: A retrospective analysis. Lancet Child and Adolescent Health, 3(8), 539-547. https://doi.org/10.1016/s2352-4642%2819%2930193-2

• Journal Article Type: Article
• Acceptance Date: Mar 27, 2019
• Online Publication Date: Jun 7, 2019
• Publication Date: Aug 1, 2019
• Deposit Date: Jul 20, 2020
• Publicly Available Date: Jul 22, 2020
• Journal: The Lancet Child and Adolescent Health
• Print ISSN: 2352-4642
• Electronic ISSN: 2352-4642
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 3
• Issue: 8
• Pages: 539-547
• DOI: https://doi.org/10.1016/s2352-4642%2819%2930193-2
• Public URL: https://uwe-repository.worktribe.com/output/6137354