All Outputs (77)

The asteroid trillionaires (2018)
Journal Article
Glester, A. (2018). The asteroid trillionaires. Physics World, 31(6), 33-35. https://doi.org/10.1088/2058-7058/31/6/29

The race to the riches of asteroids is on, with several private companies vying for funding to become the first space miners. Andrew Glester digs into the issues involved in making money from asteroids.

ICT Use and Physical Activity & Implication for Musculoskeletal Pains among Tertiary Institution Students in Kwara State Nigeria: 1027 Board #288 May 30 3 30 PM - 5 00 PM (2018)
Journal Article
Iliasu, S. Y., Dominic, O. L., Niyi-Odumosu, F. A., & Adetayo, T. E. (2018). ICT Use and Physical Activity & Implication for Musculoskeletal Pains among Tertiary Institution Students in Kwara State Nigeria: 1027 Board #288 May 30 3 30 PM - 5 00 PM. Medicine and Science in Sports and Exercise, 50(5S), 244. https://doi.org/10.1249/01.mss.0000535891.49810.3d

PURPOSE: Recent studies show that prolonged ICT use is associated with increased sedentariness and postural imbalances. This has implication for the prevalence of musculoskeletal pains among ICT users. To investigate the implications of ICT use for p... Read More about ICT Use and Physical Activity & Implication for Musculoskeletal Pains among Tertiary Institution Students in Kwara State Nigeria: 1027 Board #288 May 30 3 30 PM - 5 00 PM.

Autoregulation of the human splice factor kinase CLK1 through exon skipping and intron retention (2018)
Journal Article
Uzor, S., Zorzou, P., Bowler, E., Porazinski, S., Wilson, I. D., & Ladomery, M. (2018). Autoregulation of the human splice factor kinase CLK1 through exon skipping and intron retention. Gene, 670, 46-54. https://doi.org/10.1016/j.gene.2018.05.095

© 2018 Elsevier B.V. Alternative splicing is a key process required for the regulation of gene expression in normal development and physiology. It is regulated by splice factors whose activities are in turn regulated by splice factor kinases and phos... Read More about Autoregulation of the human splice factor kinase CLK1 through exon skipping and intron retention.

Kidney symptom questionnaire: Development, content validation and relationship with quality of life (2018)
Journal Article
Brown, S. A., Tyrer, F., Clarke, A. L., Lloyd-Davies, L. H., Niyi-Odumosu, F. A., Nah, R. G. Q., …Smith, A. C. (2018). Kidney symptom questionnaire: Development, content validation and relationship with quality of life. Journal of Renal Care, 44(3), 162-173. https://doi.org/10.1111/jorc.12247

Background: Chronic kidney disease (CKD) is associated with a range of symptoms, even at early stages. The importance of patient symptom experience is increasingly recognised, but validated symptom scores are lacking. Objectives: This study aimed to... Read More about Kidney symptom questionnaire: Development, content validation and relationship with quality of life.

Optimized delivery of siRNA into 3D tumor spheroid cultures in situ (2018)
Journal Article
Morgan, R. G., Chambers, A. C., Legge, D. N., Coles, S. J., Greenhough, A., & Williams, A. C. (2018). Optimized delivery of siRNA into 3D tumor spheroid cultures in situ. Scientific Reports, 8, Article 7952. https://doi.org/10.1038/s41598-018-26253-3

© 2018 The Author(s). 3D tissue culture provides a physiologically relevant and genetically tractable system for studying normal and malignant human tissues. Despite this, gene-silencing studies using siRNA has proved difficult. In this study, we hav... Read More about Optimized delivery of siRNA into 3D tumor spheroid cultures in situ.

Electropenetrography application and molecular-based virus detection in mealybug (Hemiptera: Pseudococcidae) vectors of Cacao swollen shoot virus on Theobroma cacao L. (2018)
Journal Article
Obok, E., Wetten, A., & Allainguillaume, J. (2018). Electropenetrography application and molecular-based virus detection in mealybug (Hemiptera: Pseudococcidae) vectors of Cacao swollen shoot virus on Theobroma cacao L. Annals of Agricultural Sciences, 63(1), 55-65. https://doi.org/10.1016/j.aoas.2018.04.004

© 2018 Cacao swollen shoot virus (CSSV) is a peril exclusive to the West African cacao-growing countries; causing the Cacao swollen shoot virus disease. This study was set out (1) to analyse the feeding behaviour of two West African and one non-West... Read More about Electropenetrography application and molecular-based virus detection in mealybug (Hemiptera: Pseudococcidae) vectors of Cacao swollen shoot virus on Theobroma cacao L..

Chondrogenic differentiation of human chondrocytes cultured in the absence of ascorbic acid (2018)
Journal Article
Asnaghi, M. A., Duhr, R., Quasnichka, H., Hollander, A. P., Kafienah, W., Martin, I., & Wendt, D. (2018). Chondrogenic differentiation of human chondrocytes cultured in the absence of ascorbic acid. Journal of Tissue Engineering and Regenerative Medicine, 12(6), 1402-1411. https://doi.org/10.1002/term.2671

Bioreactor systems will likely play a key role in establishing regulatory compliant and cost-effective production systems for manufacturing engineered tissue grafts for clinical applications. However, the automation of bioreactor systems could become... Read More about Chondrogenic differentiation of human chondrocytes cultured in the absence of ascorbic acid.

Reactive oxygen species, nitric oxide and hydrogen sulfide in plant cell regulation (2018)
Journal Article
Hancock, J., & Whiteman, M. (2018). Reactive oxygen species, nitric oxide and hydrogen sulfide in plant cell regulation. Free Radical Biology and Medicine, 120(S1), s9. https://doi.org/10.1016/j.freeradbiomed.2018.04.040

Growth and maintenance of cells is partly controlled by the production and perception of a range of small relatively reactive molecules, including reactive oxygen species, nitric oxide and hydrogen sulfide: what may be dubbed reactive signaling molec... Read More about Reactive oxygen species, nitric oxide and hydrogen sulfide in plant cell regulation.

Nostalgia as a psychological resource for people with dementia: A systematic review and meta-analysis of evidence of effectiveness from experimental studies (2018)
Journal Article
Ismail, S. U., Cheston, R., Christopher, G., & Meyrick, J. (2020). Nostalgia as a psychological resource for people with dementia: A systematic review and meta-analysis of evidence of effectiveness from experimental studies. Dementia, 19(2), 330-351. https://doi.org/10.1177/1471301218774909

Objective: This review systematically examines evidence relating to the effect of nostalgia on psychological well-being through a meta-analysis of measures of social connectedness, self-esteem, meaning in life, self-continuity, optimism and positive... Read More about Nostalgia as a psychological resource for people with dementia: A systematic review and meta-analysis of evidence of effectiveness from experimental studies.

Fabrication of miniaturised screen-printed glucose biosensors, using a water-based ink, and the evaluation of their electrochemical behaviour (2018)
Journal Article
Hughes, G., Pemberton, R. . M., Nicholas, P., & Hart, J. P. (2018). Fabrication of miniaturised screen-printed glucose biosensors, using a water-based ink, and the evaluation of their electrochemical behaviour. Electroanalysis, 30(8), 1608-1612. https://doi.org/10.1002/elan.+201+800+104

This paper describes a simple, convenient approach to the fabrication of microband electrodes and microband biosensors based on screen printing technology. These devices were printed in a three-electrode configuration on one strip; a silver/silver ch... Read More about Fabrication of miniaturised screen-printed glucose biosensors, using a water-based ink, and the evaluation of their electrochemical behaviour.

Aggrecanase degradation of type III collagen is associated with clinical knee pain (2018)
Journal Article
Bay-Jensen, A., Kjelgaard-Petersen, C., Petersen, K., Arendt-Nielsen, L., Quasnichka, H., Mobasheri, A., …Leeming, D. (2018). Aggrecanase degradation of type III collagen is associated with clinical knee pain. Clinical Biochemistry, 58, 37-43. https://doi.org/10.1016/j.clinbiochem.2018.04.022

There is a lack of biochemical markers for non-invasive and objective assessment of symptomatic osteoarthritis (OA). Aggrecanase activity has been shown to be associated with joint deterioration and symptomatic disease through the degradation of extr... Read More about Aggrecanase degradation of type III collagen is associated with clinical knee pain.

The sequence of two bacteriophages with hypermodified bases reveals novel phage-host interactions (2018)
Journal Article
Kropinski, A., Turner, D., Nash, J., Ackermann, H. W., Lingohr, E., Warren, R., …Ehrlich, M. (2018). The sequence of two bacteriophages with hypermodified bases reveals novel phage-host interactions. Viruses, 10(5), Article 217. https://doi.org/10.3390/v10050217

© 2018 by the authors. Licensee MDPI, Basel, Switzerland. Bacteriophages SP-15 and ΦW-14 are members of the Myoviridae infecting Bacillus subtilis and Delftia (formerly Pseudomonas) acidovorans, respectively. What links them is that in both cases, ap... Read More about The sequence of two bacteriophages with hypermodified bases reveals novel phage-host interactions.

Coping with environmental eukaryotes; identification of pseudomonas syringae genes during the interaction with alternative hosts or predators (2018)
Journal Article
Dorati, F., Barrett, G. A., Sanchez-Contreras, M., Arseneault, T., José, M. S., Studholme, D. J., …Jackson, R. W. (2018). Coping with environmental eukaryotes; identification of pseudomonas syringae genes during the interaction with alternative hosts or predators. Microorganisms, 6(2), Article 32. https://doi.org/10.3390/microorganisms6020032

Understanding the molecular mechanisms underpinning the ecological success of plant pathogens is critical to develop strategies for controlling diseases and protecting crops. Recent observations have shown that plant pathogenic bacteria, particularly... Read More about Coping with environmental eukaryotes; identification of pseudomonas syringae genes during the interaction with alternative hosts or predators.

Immunotherapeutic and pharmacological approaches for the treatment of Alzheimer’s disease (2018)
Journal Article
Usmari Moraes, M., Gaudet, T., Hull, J., & Conway, M. E. (2018). Immunotherapeutic and pharmacological approaches for the treatment of Alzheimer’s disease. Bioscience Horizons, 11, 1-7

The development of efficacious treatments targeting Alzheimer’s disease (AD) aetiology has been proved an extensive, time consuming task. Currently prescribed therapies, primarily acetylcholinesterase inhibitors such as donepezil and the NMDAreceptor... Read More about Immunotherapeutic and pharmacological approaches for the treatment of Alzheimer’s disease.

Anodic stripping voltammetric determination of zinc at a 3-D printed carbon nanofiber–graphite–polystyrene electrode using a carbon pseudo-reference electrode (2018)
Journal Article
Honeychurch, K. C., Rymansaib, Z., & Iravani, P. (2018). Anodic stripping voltammetric determination of zinc at a 3-D printed carbon nanofiber–graphite–polystyrene electrode using a carbon pseudo-reference electrode. Sensors and Actuators B: Chemical, 267, 476-482. https://doi.org/10.1016/j.snb.2018.04.054

© 2018 Elsevier B.V. The application of a novel fully 3-D printed carbon nanofiber–graphite–polystyrene electrode has been investigated for the trace determination of Zn2+ by differential pulse anodic stripping voltammetry. The possibility of utilisi... Read More about Anodic stripping voltammetric determination of zinc at a 3-D printed carbon nanofiber–graphite–polystyrene electrode using a carbon pseudo-reference electrode.

Influence of occupational physical activity on anthropometric profile and body composition of bricklayers in Kwara state, Nigeria (2018)
Journal Article
Leah, D. O., Omokwa, E. A., Yakubu, S. I., Adeyinka, N. F., & Florence, O. (2018). Influence of occupational physical activity on anthropometric profile and body composition of bricklayers in Kwara state, Nigeria. Exercise Medicine, 2, Article 7. https://doi.org/10.26644/em.2018.007

Objectives Optimal amount of muscle and fat mass has been associated with level of physical activity and are basic determinants of individuals’ health, fitness including occupational performance. The study determined the level of occupational physic... Read More about Influence of occupational physical activity on anthropometric profile and body composition of bricklayers in Kwara state, Nigeria.

A study of column equilibration time in hydrophilic interaction chromatography (2018)
Journal Article
McCalley, D. V. (2018). A study of column equilibration time in hydrophilic interaction chromatography. Journal of Chromatography A, 1554, 61-70. https://doi.org/10.1016/j.chroma.2018.04.016

© 2018 Elsevier B.V. The time taken to achieve full column equilibration for isocratic analysis of acidic, basic, and neutral solutes in hydrophilic interaction liquid chromatography (HILIC) was compared using the mobile phase disturbance method, col... Read More about A study of column equilibration time in hydrophilic interaction chromatography.

Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells (2018)
Journal Article
Bowler, E., Porazinski, S., Uzor, S., Thibault, P., Durand, M., Lapointe, E., …Ladomery, M. (2018). Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells. BMC Cancer, 18(1), 355. https://doi.org/10.1186/s12885-018-4227-7

© 2018 The Author(s). Background: Mounting evidence suggests that one of the ways that cells adapt to hypoxia is through alternative splicing. The aim of this study was firstly to examine the effect of hypoxia on the alternative splicing of cancer as... Read More about Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells.

Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes (2018)
Journal Article
Hawkins, S. J., Crompton, L. A., Sood, A., Saunders, M., Boyle, N. T., Buckley, A., …Caldwell, M. A. (2018). Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes. Nature Nanotechnology, 13(5), 427-433. https://doi.org/10.1038/s41565-018-0085-3

The potential for maternal nanoparticle (NP) exposures to cause developmental toxicity in the fetus without the direct passage of NPs has previously been shown, but the mechanism remained elusive. We now demonstrate that exposure of cobalt and chromi... Read More about Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes.

Molecular evidence of Cacao swollen shoot virus acquisition and retention by Planococcus citri (Risso) and Pseudococcus longispinus (Targioni-Tozzetti) and Pseudococcus viburni (Signoret) Mealybugs (Hemiptera: Pseudococcidae) (2018)
Journal Article
Allainguillaume, J., Wetten, A., & Obok, E. (2018). Molecular evidence of Cacao swollen shoot virus acquisition and retention by Planococcus citri (Risso) and Pseudococcus longispinus (Targioni-Tozzetti) and Pseudococcus viburni (Signoret) Mealybugs (Hemiptera: Pseudococcidae). https://doi.org/10.29322/IJSRP.8.3.2018.p7507

Cacao swollen shoot virus (CSSV) remains a significant viral pathogen endemic in West African cacao-growing countries. Eradication of affected trees (complete removal) and resistance breeding in existing cacao (Theobroma cacao L.) germplasm have not... Read More about Molecular evidence of Cacao swollen shoot virus acquisition and retention by Planococcus citri (Risso) and Pseudococcus longispinus (Targioni-Tozzetti) and Pseudococcus viburni (Signoret) Mealybugs (Hemiptera: Pseudococcidae).