All Outputs (87)

Gastric residual volume measurement in UK paediatric intensive care units: A survey of practice (2019)
Journal Article
Tume, L., Arch, B., Woolfall, K., Latten, L., Deja, E., Roper, L., …Dorling, J. (2019). Gastric residual volume measurement in UK paediatric intensive care units: A survey of practice. Pediatric Critical Care Medicine, 20(8), 707-713. https://doi.org/10.1097/PCC.0000000000001944

Objective: Despite little evidence, the practice of routine measurement of gastric residual volume to guide both the initiation and delivery of enteral feeding in pediatric intensive care units is widespread internationally. In light of increased scr... Read More about Gastric residual volume measurement in UK paediatric intensive care units: A survey of practice.

Enhancing practitioners’ confidence in recruitment and consent in the EcLiPSE trial: A mixed-method evaluation of site training – a Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study (2019)
Journal Article
Woolfall, K., Roper, L., Humphreys, A., Lyttle, M. D., Messahel, S., Lee, E., …Appleton, R. (2019). Enhancing practitioners’ confidence in recruitment and consent in the EcLiPSE trial: A mixed-method evaluation of site training – a Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study. Trials, 20, Article 181. https://doi.org/10.1186/s13063-019-3273-z

Background: EcLiPSE (Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus in children) is a randomised controlled trial (RCT) in the United Kingdom. Challenges to success include the need to immediately administer an intervention... Read More about Enhancing practitioners’ confidence in recruitment and consent in the EcLiPSE trial: A mixed-method evaluation of site training – a Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study.

The experience of people with rheumatoid arthritis living with fatigue: A qualitative metasynthesis (2019)
Journal Article
Primdahl, J., Hegelund, A., Lorenzen, A. G., Løppenthin, K., Dures, E., & Esbensen, B. A. (2019). The experience of people with rheumatoid arthritis living with fatigue: A qualitative metasynthesis. BMJ Open, 9(3), Article e024338. https://doi.org/10.1136/bmjopen-2018-024338

Objectives To identify, appraise and synthesise qualitative studies on the experience of living with rheumatoid arthritis (RA)-related fatigue. Methods We conducted a qualitative metasynthesis encompassing a systematic literature search in Febr... Read More about The experience of people with rheumatoid arthritis living with fatigue: A qualitative metasynthesis.

Update on outcome measure development in large-vessel vasculitis: Report from OMERACT 2018 (2019)
Journal Article
Merkel, P. A., Direskeneli, H., Tugwell, P., Tómasson, G., Shea, B., Milman, N., …Hill, C. (2019). Update on outcome measure development in large-vessel vasculitis: Report from OMERACT 2018. Journal of Rheumatology, 46(9), 1198-1201. https://doi.org/10.3899/jrheum.181072

OBJECTIVE: The OMERACT Vasculitis Working Group seeks to develop validated outcome measures for use in trials for large-vessel vasculitis (LVV). METHODS: An international Delphi exercise conducted among investigators identified items considered... Read More about Update on outcome measure development in large-vessel vasculitis: Report from OMERACT 2018.

Prospective observational study of vaginal microbiota pre‐ and post‐rescue cervical cerclage (2019)
Journal Article
Brown, R. G., Chan, D., Terzidou, V., Lee, Y. S., Smith, A., Marchesi, J. R., …Bennett, P. R. (2019). Prospective observational study of vaginal microbiota pre‐ and post‐rescue cervical cerclage. BJOG: An International Journal of Obstetrics and Gynaecology, 126(7), 916-925. https://doi.org/10.1111/1471-0528.15600

Objective: To investigate the relation between vaginal microbiota composition and outcome of rescue cervical cerclage. Design: Prospective observational study. Setting: Queen Charlotte's and Chelsea Hospital, London. Population: Twenty singleton preg... Read More about Prospective observational study of vaginal microbiota pre‐ and post‐rescue cervical cerclage.

Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: A multicentre randomized clinical pilot trial (2019)
Journal Article
Peters, M. J., Woolfall, K., Khan, I., Deja, E., Mouncey, P. R., Wulff, J., …Rowan, K. M. (2019). Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: A multicentre randomized clinical pilot trial. Critical Care, 23(1), https://doi.org/10.1186/s13054-019-2354-4

Background: Fever improves pathogen control at a significant metabolic cost. No randomized clinical trials (RCT) have compared fever treatment thresholds in critically ill children. We performed a pilot RCT to determine whether a definitive trial of... Read More about Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: A multicentre randomized clinical pilot trial.

Traumatic brain injury in young children with isolated scalp haematoma (2019)
Journal Article
Bressan, S., Kochar, A., Oakley, E., Borland, M., Phillips, N., Dalton, S., …Babl, F. E. (2019). Traumatic brain injury in young children with isolated scalp haematoma. Archives of Disease in Childhood, 104(7), 664-669. https://doi.org/10.1136/archdischild-2018-316066

Objective Despite high-quality paediatric head trauma clinical prediction rules, the management of otherwise asymptomatic young children with scalp haematomas (SH) can be difficult. We determined the risk of intracranial injury when SH is the only pr... Read More about Traumatic brain injury in young children with isolated scalp haematoma.

Feasibility and construct validation of the Patient Reported Outcomes Measurement Information System (PROMIS) in systemic vasculitis (2019)
Journal Article
Tomasson, G., Farrar, J. T., Cuthbertson, D., McAlear, C. A., Ashdown, S., Cronholm, P. F., …Merkel, P. A. (2019). Feasibility and construct validation of the Patient Reported Outcomes Measurement Information System (PROMIS) in systemic vasculitis. Journal of Rheumatology, 46(8), 928-934. https://doi.org/10.3899/jrheum.171405

OBJECTIVE: The Patient Reported Outcome Measurement Information System (PROMIS) is a collection of item banks of self-reported health. This study assessed the feasibility and construct validity of using PROMIS instruments in vasculitis. METHODS: Data... Read More about Feasibility and construct validation of the Patient Reported Outcomes Measurement Information System (PROMIS) in systemic vasculitis.

Impact of patient global assessment on achieving remission in patients with rheumatoid arthritis: A multinational study using the METEOR database (2019)
Journal Article
Ferreira, R. J. O., Carvalho, P. D., Ndosi, M., Duarte, C., Chopra, A., Murphy, E., …da Silva, J. A. P. (2019). Impact of patient global assessment on achieving remission in patients with rheumatoid arthritis: A multinational study using the METEOR database. Arthritis Care and Research, 71(10), 1317-1325. https://doi.org/10.1002/acr.23866

OBJECTIVE: There is an ongoing debate about excluding patient's global assessment (PtGA) from composite and Boolean-based definitions of rheumatoid arthritis (RA) remission. This study aimed at determining the influence of PtGA on RA disease states,... Read More about Impact of patient global assessment on achieving remission in patients with rheumatoid arthritis: A multinational study using the METEOR database.

The development of the ICIQ-UAB: A patient reported outcome measure for underactive bladder (2019)
Journal Article
Uren, A. D., Cotterill, N., Harding, C., Hillary, C., Chapple, C., Lasch, K., …Abrams, P. (2019). The development of the ICIQ-UAB: A patient reported outcome measure for underactive bladder. Neurourology and Urodynamics, 38(3), 996-1004. https://doi.org/10.1002/nau.23947

Aims: To present the development of the International Consultation on Incontinence Questionnaire-underactive bladder (ICIQ-UAB) as the first patient reported outcome measure for the assessment of the symptoms and impact on the health-related quality... Read More about The development of the ICIQ-UAB: A patient reported outcome measure for underactive bladder.

Incidence of medically attended paediatric burns across the UK (2019)
Journal Article
Davies, K., Johnson, E. L., Hollén, L., Jones, H. M., Lyttle, M. D., Maguire, S., & Kemp, A. M. (2020). Incidence of medically attended paediatric burns across the UK. Injury Prevention, 26(1), 24-30. https://doi.org/10.1136/injuryprev-2018-042881

Objective: Childhood burns represent a burden on health services, yet the full extent of the problem is difficult to quantify. We estimated the annual UK incidence from primary care (PC), emergency attendances (EA), hospital admissions (HA) and death... Read More about Incidence of medically attended paediatric burns across the UK.

Barriers to implementing antimicrobial stewardship programmes in three Saudi hospitals: Evidence from a qualitative study (2019)
Journal Article
Alghamdi, S., Atef-Shebl, N., Aslanpour, Z., & Berrou, I. (2019). Barriers to implementing antimicrobial stewardship programmes in three Saudi hospitals: Evidence from a qualitative study. Journal of Global Antimicrobial Resistance, 18, 284-290. https://doi.org/10.1016/j.jgar.2019.01.031

© 2019 International Society for Chemotherapy of Infection and Cancer Objectives: This study explored antimicrobial stewardship programme (ASP) team members’ perspectives regarding factors influencing the adoption and implementation of these programm... Read More about Barriers to implementing antimicrobial stewardship programmes in three Saudi hospitals: Evidence from a qualitative study.

Self-management support intervention for parents of children with developmental disorders: The role of gratitude and hope (2019)
Journal Article
Martin, F., Clyne, W., Pearce, G., & Turner, A. (2019). Self-management support intervention for parents of children with developmental disorders: The role of gratitude and hope. Journal of Child and Family Studies, 28(4), 980-992. https://doi.org/10.1007/s10826-018-01308-1

Objectives: Many parents of children with developmental disabilities, including autism spectrum disorders and attention deficit disorders, experience poor well-being and increased anxiety and depression. Very few interventions directly target parents... Read More about Self-management support intervention for parents of children with developmental disorders: The role of gratitude and hope.

Preliminary piloting and validation of a questionnaire identifying basic clinical skills practised by research nurses (2019)
Journal Article
Kirkpatrick, S., Harding, S., Pollard, K., & Tacchi, P. (2019). Preliminary piloting and validation of a questionnaire identifying basic clinical skills practised by research nurses. British Journal of Nursing, 28(3), 162-167. https://doi.org/10.12968/bjon.2019.28.3.162

Clinical research nurses (CRNs) need to be competent in both clinical and research skills. In the past 10 years there has been increasing focus on developing the research competencies of CRNs. Employers, however, use the nurses’ registered status as... Read More about Preliminary piloting and validation of a questionnaire identifying basic clinical skills practised by research nurses.

Design and implementation of a large and complex trial in emergency medical services (2019)
Journal Article
Robinson, M. J., Taylor, J., Brett, S. J., Nolan, J. P., Thomas, M., Reeves, B. C., …Benger, J. R. (2019). Design and implementation of a large and complex trial in emergency medical services. Trials, 20, Article 108. https://doi.org/10.1186/s13063-019-3203-0

Background: The research study titled “Cluster randomised trial of the clinical and cost effectiveness of the i-gel supraglottic airway device versus tracheal intubation in the initial airway management of out-of-hospital cardiac arrest (AIRWAYS-2)”... Read More about Design and implementation of a large and complex trial in emergency medical services.

Systemic vasculitis and patient-reported outcomes: How the assessment of patient preferences and perspectives could improve outcomes (2019)
Journal Article
Robson, J., Jayne, D., Merkel, P., & Dawson, J. (2019). Systemic vasculitis and patient-reported outcomes: How the assessment of patient preferences and perspectives could improve outcomes. Patient Related Outcome Measures, 10, 37-42. https://doi.org/10.2147/PROM.S163601

The systemic vasculitides are a group of multisystem diseases, which can be life and organ threatening. High-dose immunosuppressants are required to control inflammation in vital organs, such as the kidneys, lungs, skin, joints, and eyes. Patients re... Read More about Systemic vasculitis and patient-reported outcomes: How the assessment of patient preferences and perspectives could improve outcomes.

Canadian and UK/Ireland practice patterns in lumbar puncture performance in febrile neonates with bronchiolitis (2019)
Journal Article
Simone, L., Lyttle, M. D., Roland, D., Stephens, D., & Schuh, S. (2019). Canadian and UK/Ireland practice patterns in lumbar puncture performance in febrile neonates with bronchiolitis. Emergency Medicine Journal, 36(3), 148-153. https://doi.org/10.1136/emermed-2018-208000

Background Serious bacterial infections in young infants with bronchiolitis are rare. Febrile infants

Reducing arthritis fatigue impact: Two-year randomised controlled trial of cognitive behavioural approaches by rheumatology teams (RAFT) (2019)
Journal Article
Hewlett, S., Almeida, C., Ambler, N., Blair, P. S., Choy, E. H., Dures, E., …Pollock, J. (2019). Reducing arthritis fatigue impact: Two-year randomised controlled trial of cognitive behavioural approaches by rheumatology teams (RAFT). Annals of the Rheumatic Diseases, 78(4), 465-472. https://doi.org/10.1136/annrheumdis-2018-214469

© Author(s) (or their employer(s)) 2019. Objectives To see if a group course delivered by rheumatology teams using cognitive-behavioural approaches, plus usual care, reduced RA fatigue impact more than usual care alone. Methods Multicentre, 2-year ra... Read More about Reducing arthritis fatigue impact: Two-year randomised controlled trial of cognitive behavioural approaches by rheumatology teams (RAFT).

Updating OMERACT core set of domains for ANCA-associated vasculitis: Patient perspective using the international classification of function, disability, and health (2019)
Journal Article
Milman, N., McConville, E., Robson, J. C., Boonen, A., Tugwell, P., Wells, G. A., …Merkel, P. A. (2019). Updating OMERACT core set of domains for ANCA-associated vasculitis: Patient perspective using the international classification of function, disability, and health. Journal of Rheumatology, 46(10), 1415-1420. https://doi.org/10.3899/jrheum.181073

Objective: Aspects of ANCA-associated vasculitis (AAV) prioritized by patients with AAV were described using the International Classification of Function, Disability, and Health. Methods: Items identified during 14 individual interviews were incorpor... Read More about Updating OMERACT core set of domains for ANCA-associated vasculitis: Patient perspective using the international classification of function, disability, and health.

Collective knowledge brokering: The model and impact of an embedded team (2019)
Journal Article
Le May, A., Wye, L., Cramer, H., Beckett, K., Farr, M., Le May, A., …Baxter, H. (2020). Collective knowledge brokering: The model and impact of an embedded team. Evidence and Policy, 16(3), 429-452. https://doi.org/10.1332/174426419X15468577044957

Background: The Bristol Knowledge Mobilisation (KM) Team was an unusual collective brokering model, consisting of a multi-professional team of four managers and three academics embedded in both local healthcare policymaking (aka commissioning) and ac... Read More about Collective knowledge brokering: The model and impact of an embedded team.