Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids (2023)
Journal Article
Smart, A., Crew, A., Doran, O., & Hart, J. (2023). Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids. Journal of Food Composition and Analysis, 122, Article 105488. https://doi.org/10.1016/j.jfca.2023.105488

This paper describes, for the first time, the development of a novel trilinolein biosensor based on the immobilisation of lipase and lipoxygenase (LOX) onto a cobalt phthalocyanine screen-printed carbon electrode (CoPC-SPCE) in conjunction with amper... Read More about Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids.

Sex estimation from virtual models: Exploring the potential of stereolithic (STL) 3D crania models for morphoscopic trait scoring (2023)
Journal Article
Robles, M., Carew, R. M., Rando, C., Nakhaeizadeh, S., & Morgan, R. M. (2023). Sex estimation from virtual models: Exploring the potential of stereolithic (STL) 3D crania models for morphoscopic trait scoring. Forensic Sciences Research, 8(2), 123-132. https://doi.org/10.1093/fsr/owad017

Modern computed tomography (CT) databases are becoming an accepted resource for the practice and development of identification methods in forensic anthropology. However, the utility of 3D models created using free and open-source visualization softwa... Read More about Sex estimation from virtual models: Exploring the potential of stereolithic (STL) 3D crania models for morphoscopic trait scoring.

Genotoxicity of cytokines at chemotherapy-induced 'storm' concentrations in a model of the human bone marrow (2023)
Journal Article
Asurappulige, H. S. H., Thomas, A. D., & Morse, H. R. (2023). Genotoxicity of cytokines at chemotherapy-induced 'storm' concentrations in a model of the human bone marrow. Mutagenesis, 38(4), 201-215. https://doi.org/10.1093/mutage/gead018

Donor cell leukaemia (DCL) is a complication of haematopoietic stem cell transplantation where donated cells become malignant within the patient's bone marrow. As DCL predominates as acute myeloid leukaemia, we hypothesized that the cytokine storm fo... Read More about Genotoxicity of cytokines at chemotherapy-induced 'storm' concentrations in a model of the human bone marrow.

Why Elephants Cry: How Observing Unusual Animal Behaviours Can Predict the Weather (and other Environmental Phenomena) (2023)
Book
Hancock, J. (2023). Why Elephants Cry: How Observing Unusual Animal Behaviours Can Predict the Weather (and other Environmental Phenomena). Taylor & Francis (Routledge)

Why Elephants Cry is a fascinating frolic through the literature and evidence surrounding the use of unusual behavior of animals to measure and predict the environment. The role of animals, from the smallest ant to the biggest elephant, as predictors... Read More about Why Elephants Cry: How Observing Unusual Animal Behaviours Can Predict the Weather (and other Environmental Phenomena).

New boundaries: Redefining the geographical range of a threatened fish through environmental DNA survey (2023)
Journal Article
Kalogianni, E., Zogaris, S., Leris, I., Laschou, S., Zimmerman, B., Meek, S., …Steer, M. D. (2023). New boundaries: Redefining the geographical range of a threatened fish through environmental DNA survey. Environmental DNA, 5(4), 697-705. https://doi.org/10.1002/edn3.428

Accurate data on the distribution and population status of threatened fish species are fundamental for effective conservation planning and management. In this work, in order to reassess the distribution of the globally threatened Evia barbel, Barbus... Read More about New boundaries: Redefining the geographical range of a threatened fish through environmental DNA survey.

Metabolic reprogramming and the role of the BCAT protein - implications for type 2 diabetes and Alzheimer's disease (2023)
Thesis
Usmari Moraes, M. Metabolic reprogramming and the role of the BCAT protein - implications for type 2 diabetes and Alzheimer's disease. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/10013675

Introduction: Oxidative stress and impaired homeostasis are key features of type 2 diabetes mellitus, which is comorbid with Alzheimer’s disease. Dysregulation of the branched-chain aminotransferase protein, which is overexpressed in AD, is suggested... Read More about Metabolic reprogramming and the role of the BCAT protein - implications for type 2 diabetes and Alzheimer's disease.

Human stem cell-derived ventral midbrain astrocytes exhibit a region-specific secretory profile (2023)
Journal Article
Crompton, L., McComish, S. F., Steward, T., Whitcomb, D., Lane, J., & Caldwell, M. (2023). Human stem cell-derived ventral midbrain astrocytes exhibit a region-specific secretory profile. Brain Communications, 5(2), https://doi.org/10.1093/braincomms/fcad114

This scientific commentary refers to ‘Human stem cell-derived astrocytes exhibit region-specific heterogeneity in their secretory profiles’, by Clarke et al. (https://doi.org/10.1093/brain/awaa258) in Brain.

Development of an antimicrobial lipid coating to prevent infections in uncemented joint replacements (2023)
Journal Article
Azizova, L., Morgan, D., Rowlands, J., Brousseau, E., Kulik, T., Palianytsia, B., …Ayre, W. (2023). Development of an antimicrobial lipid coating to prevent infections in uncemented joint replacements. Orthopaedic Proceedings, 105-B(SUPP_9), 80-80. https://doi.org/10.1302/1358-992x.2023.9.080

Preventing infections in joint replacements is a major ongoing challenge, with limited effective clinical technologies currently available for uncemented knee and hip prostheses. This research aims to develop a coating for titanium implants, consisti... Read More about Development of an antimicrobial lipid coating to prevent infections in uncemented joint replacements.

Promoting dietary changes for achieving health and sustainability targets (2023)
Journal Article
Sanderson Bellamy, A., Furness, E., Mills, S., Clear, A., Finnigan, S. M., Meador, E., …Sharp, R. T. (2023). Promoting dietary changes for achieving health and sustainability targets. Frontiers in Sustainable Food Systems, 7, Article 1160627. https://doi.org/10.3389/fsufs.2023.1160627

Globally, about 21–37% of total greenhouse gas (GHG) emissions are attributable to food systems. Dietary-related non-communicable diseases have increased significantly from 1990–2019 at a global scale. To achieve carbon emissions targets, increase re... Read More about Promoting dietary changes for achieving health and sustainability targets.

The on/off history of hydrogen in medicine: Will the interest persist this time around? (2023)
Journal Article
LeBaron, T. W., Ohno, K., & Hancock, J. T. (2023). The on/off history of hydrogen in medicine: Will the interest persist this time around?. Oxygen, 3(1), 143-162. https://doi.org/10.3390/oxygen3010011

Over 2000 publications including more than 100 human studies seem to indicate that humans have only recently benefited from or known about the medical effects of H2 within the past 15 years. However, we have unknowingly benefited from H2 since the da... Read More about The on/off history of hydrogen in medicine: Will the interest persist this time around?.

The early history of hydrogen and other gases in respiration and biological systems: Revisiting Beddoes, Cavallo, and Davy (2023)
Journal Article
Hancock, J. T., & LeBaron, T. W. (2023). The early history of hydrogen and other gases in respiration and biological systems: Revisiting Beddoes, Cavallo, and Davy. Oxygen, 3(1), 102-119. https://doi.org/10.3390/oxygen3010008

In 2007 a paper in Nature Medicine sparked a new wave of interest in the use of molecular hydrogen (H2) for medical treatments. Since then there has been a flurry of papers looking at a range of medical aspects, from neurodegenerative disease to spor... Read More about The early history of hydrogen and other gases in respiration and biological systems: Revisiting Beddoes, Cavallo, and Davy.

Slow violence and river abuse: The hidden effect of land use on water quality (2023)
Exhibition / Performance
Fahy, N., Clayton, G., bodman, S., & Reynolds, D. Slow violence and river abuse: The hidden effect of land use on water quality. [Printmaking/Photography]. Exhibited at F block Gallery, Bower Ashton, Bristol. 31 January 2023 - 3 February 2023. (Unpublished)

Researchers from HAS, Dr Gillian Clayton and Professor Darren Reynolds (HAS) and Researchers from ACE Niamh Fahy and Associate Professor Sarah Bodman have been collaborating on a project in Somerset, UK, from which Niamh is using data and samples col... Read More about Slow violence and river abuse: The hidden effect of land use on water quality.

Description of Dryocola gen. nov. and two novel species, Dryocola boscaweniae sp. nov. and Dryocola clanedunensis sp. nov. isolated from the rhizosphere of native British oaks (2023)
Journal Article
Maddock, D., Brady, C., Denman, S., & Arnold, D. (2023). Description of Dryocola gen. nov. and two novel species, Dryocola boscaweniae sp. nov. and Dryocola clanedunensis sp. nov. isolated from the rhizosphere of native British oaks. Systematic and Applied Microbiology, 46(2), Article 126399. https://doi.org/10.1016/j.syapm.2023.126399

While investigating the role of the rhizosphere in the development of Acute Oak Decline, bacterial strains belonging to the family Enterobacteriaceae were isolated from rhizosphere soil following enrichment for the Enterobacterales. Partial sequencin... Read More about Description of Dryocola gen. nov. and two novel species, Dryocola boscaweniae sp. nov. and Dryocola clanedunensis sp. nov. isolated from the rhizosphere of native British oaks.

Variations in bacteriological and physicochemical water quality characteristics of Asata River, Enugu, Nigeria (2023)
Journal Article
Ozochi, C., Nwankwo, C., Enemuor, S., Chidebelu, P., Adukwu, E., & Chigor, V. (2023). Variations in bacteriological and physicochemical water quality characteristics of Asata River, Enugu, Nigeria. Microbiology Journal, 13(1), 1-10. https://doi.org/10.3923/mj.2023.1.10

Background and Objective: Globally, river water remains an important source of water for drinking, domestic and other uses. This study aimed to assess the bacteriological and physicochemical properties of Asata River water. Materials and Methods: A... Read More about Variations in bacteriological and physicochemical water quality characteristics of Asata River, Enugu, Nigeria.

The control of pathogens in stored rainwater using direct electrochemical activation (2022)
Conference Proceeding
Clayton, G., Fox, B., Steer, M., Thorn, R., & Reynolds, D. (2022). The control of pathogens in stored rainwater using direct electrochemical activation. In IWRA Proceedings

Purpose of study or research hypothesis: The main study aim was to control waterborne pathogens using small-scale direct electrochemical activation. Key issue(s) or problem(s) addressed: Rainwater harvesting systems enable households o... Read More about The control of pathogens in stored rainwater using direct electrochemical activation.

What drives bat activity at field boundaries? (2022)
Journal Article
Foxley, T., Lintott, P., & Stone, E. (2023). What drives bat activity at field boundaries?. Journal of Environmental Management, 329, 117029. https://doi.org/10.1016/j.jenvman.2022.117029

Field boundaries are important habitat for bats in agricultural landscapes, serving as commuting and foraging areas for many species. The goal of our study was to better understand the drivers of bat activity in agricultural landscapes to inform cons... Read More about What drives bat activity at field boundaries?.

Managing biofilms in ultrafiltration membranes within a point-of-use drinking water system (2022)
Presentation / Conference
Clayton, G., Thorn, R., & Reynolds, D. (2022, December). Managing biofilms in ultrafiltration membranes within a point-of-use drinking water system. Presented at IWA Biofilms Conference 2022, Phuket, Thailand

Description of a novel species of Leclercia, Leclercia tamurae sp. nov. and proposal of a novel genus Silvania gen. nov. containing two novel species Silvania hatchlandensis sp. nov. and Silvania confinis sp. nov. isolated from the rhizosphere of oak (2022)
Journal Article
Maddock, D., Arnold, D., Denman, S., & Brady, C. (2022). Description of a novel species of Leclercia, Leclercia tamurae sp. nov. and proposal of a novel genus Silvania gen. nov. containing two novel species Silvania hatchlandensis sp. nov. and Silvania confinis sp. nov. isolated from the rhizosphere of oak. BMC Microbiology, 22(1), 289. https://doi.org/10.1186/s12866-022-02711-x

Background: Acute Oak Decline (AOD) is a decline disease first reported on native oaks in the UK, but in recent years reports from further afield such as Europe and the Middle East, indicate that the distribution and host range is increasing at an al... Read More about Description of a novel species of Leclercia, Leclercia tamurae sp. nov. and proposal of a novel genus Silvania gen. nov. containing two novel species Silvania hatchlandensis sp. nov. and Silvania confinis sp. nov. isolated from the rhizosphere of oak.

Clean water for all (2022)
Digital Artefact
Clayton, G., Steven, J., Thorn, R., & Reynolds, D. (2022). Clean water for all. [Website]

The World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF) estimated that, as of 2020, 2 billion people across the globe did not have access to safely managed drinking water. Ideally, safely managed drinking water should b... Read More about Clean water for all.

Understanding Hydrogen: Lessons to be learned from physical interactions between the inert gases and the globin superfamily (2022)
Journal Article
Hancock, J. T., Russell, G., Craig, T. J., May, J., Morse, H. R., & Stamler, J. S. (2022). Understanding Hydrogen: Lessons to be learned from physical interactions between the inert gases and the globin superfamily. Oxygen, 2(4), 578-590. https://doi.org/10.3390/oxygen2040038

Hydrogen gas (molecular hydrogen, H2) has significant effects in a range of organisms, from plants to humans. Many inert gases have been reported to have similar effects, and such responses may be most pronounced when cells are stressed. Xenon (Xe),... Read More about Understanding Hydrogen: Lessons to be learned from physical interactions between the inert gases and the globin superfamily.