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All Outputs (104)

In vitro studies comparing activities of antimicrobial photodynamic therapy and electrochemically activated solutions (2014)
Thesis
Kamil, Z. In vitro studies comparing activities of antimicrobial photodynamic therapy and electrochemically activated solutions. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/806200

Abstract There is a need for alternative “treatments” for killing microbes in wound and other body surfaces. Antimicrobial Photodynamic Therapy (APDT) and Electrochemically Activated Solutions (ECAS) are two recent developments in the field of bioci... Read More about In vitro studies comparing activities of antimicrobial photodynamic therapy and electrochemically activated solutions.

Exploring serendipitous dialogue (2014)
Journal Article
Weitkamp, E. (2014). Exploring serendipitous dialogue. JCOM: Journal of Science Communication, 13(04),

Over the past decades there has been an increasing recognition of the need to promote dialogue between science and society. Often this takes the form of formal processes, such as citizen’s juries, that are designed to allow the public to contribut... Read More about Exploring serendipitous dialogue.

Opening-up education to inspire future learners and teachers (2014)
Presentation / Conference
Rolfe, V. (2014, December). Opening-up education to inspire future learners and teachers. Paper presented at Society for Research into Higher Education Annual Conference 2014, Celtic Manor, Newport in South Wales, UK

The global open education movement involves a variety of initiatives ranging from access to educational resources, to short courses and degree programmes. We are presently in a situation where the technological advances and global demands have outpac... Read More about Opening-up education to inspire future learners and teachers.

The impact of pressure and frictional heating on retention, selectivity and efficiency in ultra-high-pressure liquid chromatography (2014)
Journal Article
McCalley, D. V. (2014). The impact of pressure and frictional heating on retention, selectivity and efficiency in ultra-high-pressure liquid chromatography. Trends in Analytical Chemistry, 63, 31-43. https://doi.org/10.1016/j.trac.2014.06.024

© 2014 Elsevier B.V. The effects of pressure and frictional heating deserve serious consideration in ultra-high-pressure liquid chromatography (UHPLC) separations, as the pressures used can be three times greater than those in conventional high-perfo... Read More about The impact of pressure and frictional heating on retention, selectivity and efficiency in ultra-high-pressure liquid chromatography.

Triple negative breast cancer: The role of metabolic pathways (2014)
Journal Article
Dean, S. J., & Rhodes, A. (2014). Triple negative breast cancer: The role of metabolic pathways. Malaysian Journal of Pathology, 36(3), 155-162

The incidence of breast cancer in Malaysia and other Asian countries is on the increase, reflecting lifestyle changes some of which are known risk factors for the development of breast cancer. Most breast cancers are amenable to adjuvant therapies th... Read More about Triple negative breast cancer: The role of metabolic pathways.

Interactions of volcanic airfall and glaciers: Appendix B to: Jenkins SF, Wilson TM, Magill CR, Miller V, Stewart C, Marzocchi W and Boulton M, 2014. Volcanic ash fall hazard and risk: technical background paper for the UNISDR 2015 Global Assessment Report on Disaster Risk Reduction (2014)
Report
Hobbs, L., Gilbert, J., Lane, S., & Loughlin, S. (2014). Interactions of volcanic airfall and glaciers: Appendix B to: Jenkins SF, Wilson TM, Magill CR, Miller V, Stewart C, Marzocchi W and Boulton M, 2014. Volcanic ash fall hazard and risk: technical background paper for the UNISDR 2015 Global Assessment Report on Disaster Risk Reduction. Global Volcano Model for UNISDR

Exploring peripheral blood mononuclear cells as the source of interleukin-6 in polymyalgia rheumatica (2014)
Thesis
Bazzard, H. L. Exploring peripheral blood mononuclear cells as the source of interleukin-6 in polymyalgia rheumatica. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/806917

Polymyalgia rheumatica (PMR) is a chronic inflammatory condition which affects the elderly, causing aching and stiffness of the neck, shoulders and pelvis, as well as more systemic manifestations such as fever, malaise and fatigue. PMR shares symptom... Read More about Exploring peripheral blood mononuclear cells as the source of interleukin-6 in polymyalgia rheumatica.

Perceptions of socio-ethical stances surrounding massive online open courses (2014)
Presentation / Conference
Kernohan, D., & Rolfe, V. (2014, November). Perceptions of socio-ethical stances surrounding massive online open courses. Paper presented at Open Education Conference 2014 (OpenEd), Washington DC, USA

Open education provides opportunities for anyone with digital access to engage in learning far beyond the classroom and throughout their lives, although this notion is not without challenges. When learners formally enrol on a course with an instituti... Read More about Perceptions of socio-ethical stances surrounding massive online open courses.

Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells (2014)
Journal Article
Malik, K., Deery, M. J., Brown, K. W., Heesom, K. J., Melegh, Z., Vieira, G. C., …Malik, K. T. (2015). Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells. Molecular Oncology, 9(3), 617-627. https://doi.org/10.1016/j.molonc.2014.10.015

© 2014 The Authors. Approximately half of poor prognosis neuroblastomas (NBs) are characterized by pathognomonic MYCN gene amplification and MYCN over-expression. Here we present data showing that short-interfering RNA mediated depletion of the prote... Read More about Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells.

Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer (2014)
Journal Article
Mavrou, A., Brakspear, K., Hamdollah-Zadeh, M., Damodaran, G., Babaei-Jadidi, R., Oxley, J., …Oltean, S. (2015). Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer. Oncogene, 34, 4311-4319. https://doi.org/10.1038/onc.2014.360

© 2015 Macmillan Publishers Limited. All rights reserved. Angiogenesis is required for tumour growth and is induced principally by vascular endothelial growth factor A (VEGF-A). VEGF-A pre-mRNA is alternatively spliced at the terminal exon to produce... Read More about Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer.

Assessing the value of imperfect biocontainment nationally: Rapeseed in the United Kingdom as an exemplar (2014)
Journal Article
Ford, C. S., Allainguillaume, J., Fu, T. R., Mitchley, J., & Wilkinson, M. J. (2015). Assessing the value of imperfect biocontainment nationally: Rapeseed in the United Kingdom as an exemplar. New Phytologist, 205(3), 1342-1349. https://doi.org/10.1111/nph.13131

© 2014 New Phytologist Trust. Paternal biocontainment methods (PBMs) act by preventing pollen-mediated transgene flow. They are compromised by transgene escape via the crop-maternal line. We therefore assess the efficacy of PBMs for transgenic rapese... Read More about Assessing the value of imperfect biocontainment nationally: Rapeseed in the United Kingdom as an exemplar.

City life makes females fussy: Sex differences in habitat use of temperate bats in urban areas (2014)
Journal Article
Park, K. J., Mayhew, R. J., Lintott, P., Bunnefeld, N., Fuentes-Montemayor, E., Minderman, J., & Olley, L. (2014). City life makes females fussy: Sex differences in habitat use of temperate bats in urban areas. Royal Society Open Science, 1(3), Article 140200. https://doi.org/10.1098/rsos.140200

© 2014 The Authors. Urbanization is a major driver of the global loss of biodiversity; to mitigate its adverse effects, it is essential to understand what drives species' patterns of habitat use within the urban matrix. While many animal species are... Read More about City life makes females fussy: Sex differences in habitat use of temperate bats in urban areas.

Topographical variation reduces phenological mismatch between a butterfly and its nectar source (2014)
Journal Article
Hindle, B. J., Kerr, C. L., Richards, S. A., & Willis, S. G. (2015). Topographical variation reduces phenological mismatch between a butterfly and its nectar source. Journal of Insect Conservation, 19(2), 227-236. https://doi.org/10.1007/s10841-014-9713-x

© 2014, Springer International Publishing Switzerland. The timing of many biological events, including butterfly imago emergence, has advanced under climate change, with the rate of these phenological changes often differing among taxonomic groups. S... Read More about Topographical variation reduces phenological mismatch between a butterfly and its nectar source.

Direct mixing of atomistic solutes and coarse-grained water (2014)
Journal Article
Orsi, M., Ding, W., & Palaiokostas, M. (2014). Direct mixing of atomistic solutes and coarse-grained water. Journal of Chemical Theory and Computation, 10(10), 4684-4693. https://doi.org/10.1021/ct500065k

© 2014 American Chemical Society. We present a new dual-resolution approach for coupling atomistic and coarse-grained models in molecular dynamics simulations of hydrated systems. In particular, a coarse-grained point dipolar water model is used to s... Read More about Direct mixing of atomistic solutes and coarse-grained water.

Convective stability of carbon sequestration in anisotropic porous media (2014)
Journal Article
Hill, A. A., & Morad, M. R. (2014). Convective stability of carbon sequestration in anisotropic porous media. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 470(2170), https://doi.org/10.1098/rspa.2014.0373

© 2014 The Author(s) Published by the Royal Society. All rights reserved. The stability of convection in an anisotropic porous medium, where the solute concentration is assumed to decay via a first-order chemical reaction, is studied. This is a simpl... Read More about Convective stability of carbon sequestration in anisotropic porous media.

Atmin is a transcriptional regulator of both lung morphogenesis and ciliogenesis (2014)
Journal Article
Stevens, J. L., Goggolidou, P., L. Stevens, J., Agueci, F., Keynton, J., Wheway, G., …Norris, D. P. (2014). Atmin is a transcriptional regulator of both lung morphogenesis and ciliogenesis. Development, 141(20), 3966-3977. https://doi.org/10.1242/dev.107755

© 2014. Initially identified in DNA damage repair, ATM-interactor (ATMIN) further functions as a transcriptional regulator of lung morphogenesis. Here we analyse three mouse mutants, Atmingpg6/gpg6, AtminH210Q/H210Q and Dynll1GT/GT, revealing how ATM... Read More about Atmin is a transcriptional regulator of both lung morphogenesis and ciliogenesis.

Novel reductive-reductive mode electrochemical detection of Rohypnol following liquid chromatography and its determination in coffee (2014)
Journal Article
Honeychurch, K. C., Davidson, G. M., Brown, E., & Hart, J. P. (2015). Novel reductive-reductive mode electrochemical detection of Rohypnol following liquid chromatography and its determination in coffee. Analytica Chimica Acta, 853, 222-227. https://doi.org/10.1016/j.aca.2014.09.033

© 2014 Elsevier B.V. Rohypnol (flunitrazepam) has been successfully determined in coffee by high performance liquid chromatography dual electrode detection (LC-DED) in the dual reductive mode. Initial studies were performed to optimise the chromatogr... Read More about Novel reductive-reductive mode electrochemical detection of Rohypnol following liquid chromatography and its determination in coffee.

On the roles of scientists, press officers and journalists (2014)
Journal Article
Weitkamp, E. (2014). On the roles of scientists, press officers and journalists. JCOM: Journal of Science Communication, 13(03),

This issue of the Journal of Science Communication raises a number of questions about the ways that new scientific research emerges from research institutions and in particular the role played by scientists, press officers and journalists in this... Read More about On the roles of scientists, press officers and journalists.

Rahnella victoriana sp. nov., Rahnella bruchi sp. nov., Rahnella woolbedingensis sp. nov., classification of Rahnella genomospecies 2 and 3 as Rahnella variigena sp. nov. and Rahnella inusitata sp. nov., respectively and emended description of the genus Rahnella (2014)
Journal Article
Brady, C., Hunter, G., Kirk, S., Arnold, D. L., & Denman, S. (2014). Rahnella victoriana sp. nov., Rahnella bruchi sp. nov., Rahnella woolbedingensis sp. nov., classification of Rahnella genomospecies 2 and 3 as Rahnella variigena sp. nov. and Rahnella inusitata sp. nov., respectively and emended description of the genus Rahnella. Systematic and Applied Microbiology, 37(8), 545-552. https://doi.org/10.1016/j.syapm.2014.09.001

© 2014 Published by Elsevier GmbH. Isolations from oak symptomatic of Acute Oak Decline, alder and walnut log tissue, and buprestid beetles in 2009-2012 yielded 32 Gram-negative bacterial strains showing highest gyrB sequence similarity to Rahnella a... Read More about Rahnella victoriana sp. nov., Rahnella bruchi sp. nov., Rahnella woolbedingensis sp. nov., classification of Rahnella genomospecies 2 and 3 as Rahnella variigena sp. nov. and Rahnella inusitata sp. nov., respectively and emended description of the genus Rahnella.