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Investigating the role of BCATc in autophagy and its implications in Alzheimer's disease (2024)
Thesis
Edward, R. Investigating the role of BCATc in autophagy and its implications in Alzheimer's disease. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/10732083

Background: Autophagy, crucial in maintaining cellular health, is often dysregulated in neurodegenerative conditions such as Alzheimer’s disease (AD). Recent data shows that the cytosolic branched chain aminotransferase (BCATc) protein plays a pivota... Read More about Investigating the role of BCATc in autophagy and its implications in Alzheimer's disease.

Minimising infection risk of implantable titanium (2023)
Thesis
Britton, S. Minimising infection risk of implantable titanium. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/10791885

The use of antibacterial coatings on bone biomaterial has attracted interest from various fields such as orthopaedics, dentistry and veterinary medicine. However, the process of attaching suitable compounds to biomaterial surfaces in a stable manner... Read More about Minimising infection risk of implantable titanium.

Promoting access to haemostasis testing in resource-scarce and emergency settings using paper-based lateral flow diagnostic screening assays for coagulation disorders (2023)
Thesis
Saidykhan, J. Promoting access to haemostasis testing in resource-scarce and emergency settings using paper-based lateral flow diagnostic screening assays for coagulation disorders. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/10774108

Haemostatic disorders cause excessive bleeding and clotting and result in high morbidity and mortality worldwide, but especially in low-income areas which often lack suitable facilities and expertise for affordable diagnosis and treatment. Simple and... Read More about Promoting access to haemostasis testing in resource-scarce and emergency settings using paper-based lateral flow diagnostic screening assays for coagulation disorders.

Art and the schizophrenic spectrum (2023)
Book Chapter
Holt, N. (2023). Art and the schizophrenic spectrum. In P. Crawford, & P. Kadetz (Eds.), Palgrave Encyclopedia of the Health Humanities. (1). Palgrave Macmillan (part of Springer Nature). https://doi.org/10.1007/978-3-030-26825-1_20-1

There is an ‘art and health’ paradox in the literature on the schizophrenic spectrum, since features of the schizophrenic spectrum have been argued to facilitate artistic creativity (e.g., by enabling novel perspectives, images or insights), suggesti... Read More about Art and the schizophrenic spectrum.

Computer simulations of peptide nucleic acid under external force (2023)
Thesis
Goodman, J. Computer simulations of peptide nucleic acid under external force. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/10829665

The research question, “Can molecular dynamics be used to assess and screen the single-molecular binding properties of a candidate bioadhesive?" is answered in this thesis using molecular dynamics simulations. A ‘nearest-neighbour’ model was produced... Read More about Computer simulations of peptide nucleic acid under external force.

The nonlinear stability analysis of double-diffusive convection with viscous dissipation effect (2023)
Journal Article
Deepika, N., Narayana, P. A. L., & Hill, A. (2023). The nonlinear stability analysis of double-diffusive convection with viscous dissipation effect. Transport in Porous Media, 150, 215–227. https://doi.org/10.1007/s11242-023-02006-3

In this article, the onset of double-diffusive convection with the effect of viscous dissipation in a horizontal fluid-saturated porous layer is examined. Two impermeable isothermal and isosolutal walls bound the porous layer, and Darcy’s law models... Read More about The nonlinear stability analysis of double-diffusive convection with viscous dissipation effect.

HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings (2023)
Journal Article
Mehendale, F. V., Mehendale, F., Homyer, K. M., Clayton, G., Reynolds, D. M., Homyer, K., & Reynolds, D. (2023). HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings. Journal of Global Health Reports, 7, Article e2023052. https://doi.org/10.29392/001c.84488

Disinfection is a mainstay of infection prevention, the importance of which was highlighted throughout the SARS-CoV-2 pandemic. There is frequent misuse of terminology surrounding chlorine solutions in the literature. This leads not only to confusion... Read More about HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings.

The impact of COVID-19 related lockdown restrictions on musculoskeletal health: A systematic review (2023)
Journal Article
Gebrye, T., Niyi-Odumosu, F., Lawoe, J., Mbada, C., & Fatoye, F. (2023). The impact of COVID-19 related lockdown restrictions on musculoskeletal health: A systematic review. Rheumatology International, 43, 2011–2019. https://doi.org/10.1007/s00296-023-05406-2

There is limited empirical evidence on whether Coronavirus disease 2019 (COVID-19) related lockdown restrictions precipitate or perpetuate musculoskeletal (MSK) disorders. This study was aimed to synthesis literature that assessed the impact of COVID... Read More about The impact of COVID-19 related lockdown restrictions on musculoskeletal health: A systematic review.

Building relationships back into the food system: Addressing food insecurity and food well-being (2023)
Journal Article
Verfuerth, C., Sanderson Bellamy, A., Adlerova, B., & Dutton, A. (2023). Building relationships back into the food system: Addressing food insecurity and food well-being. Frontiers in Sustainable Food Systems, 7, Article 1218299. https://doi.org/10.3389/fsufs.2023.1218299

Introduction: Failures of the current food system sit at the core of the multitude of crises by being the root framework for both consumption choices and food production. Low-income households are disproportionately affected by these failures, impact... Read More about Building relationships back into the food system: Addressing food insecurity and food well-being.

Nanotechnology improves disease resistance in plants for food security: Applications and challenges (2023)
Journal Article
Munir, N., Gulzar, W., Abideen, Z., Hancock, J. T., El-Keblawy, A., & Radicetti, E. (2023). Nanotechnology improves disease resistance in plants for food security: Applications and challenges. Biocatalysis and Agricultural Biotechnology, 51, Article 102781

Green synthesis of nano-fertilizers is emerging as a potential strategy and could play a crucial role in disease mitigation, diagnosis, or suppression. Different nanoscale devices (nanoparticles, NPs), biosensors, nano-diagnostic kits, nanofabricatio... Read More about Nanotechnology improves disease resistance in plants for food security: Applications and challenges.

Are protein cavities and pockets commonly used by redox active signalling molecules? (2023)
Journal Article
Hancock, J. T. (2023). Are protein cavities and pockets commonly used by redox active signalling molecules?. Plants, 12(14), 2594. https://doi.org/10.3390/plants12142594

It has been well known for a long time that inert gases, such as xenon (Xe), have significant biological effects. As these atoms are extremely unlikely to partake in direct chemical reactions with biomolecules such as proteins, lipids, and nucleic ac... Read More about Are protein cavities and pockets commonly used by redox active signalling molecules?.

Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids (2023)
Journal Article
Smart, A., Crew, A., Doran, O., & Hart, J. (2023). Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids. Journal of Food Composition and Analysis, 122, Article 105488. https://doi.org/10.1016/j.jfca.2023.105488

This paper describes, for the first time, the development of a novel trilinolein biosensor based on the immobilisation of lipase and lipoxygenase (LOX) onto a cobalt phthalocyanine screen-printed carbon electrode (CoPC-SPCE) in conjunction with amper... Read More about Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids.

Sex estimation from virtual models: Exploring the potential of stereolithic (STL) 3D crania models for morphoscopic trait scoring (2023)
Journal Article
Robles, M., Carew, R. M., Rando, C., Nakhaeizadeh, S., & Morgan, R. M. (2023). Sex estimation from virtual models: Exploring the potential of stereolithic (STL) 3D crania models for morphoscopic trait scoring. Forensic Sciences Research, 8(2), 123-132. https://doi.org/10.1093/fsr/owad017

Modern computed tomography (CT) databases are becoming an accepted resource for the practice and development of identification methods in forensic anthropology. However, the utility of 3D models created using free and open-source visualization softwa... Read More about Sex estimation from virtual models: Exploring the potential of stereolithic (STL) 3D crania models for morphoscopic trait scoring.

Assessing the impact of festival music on bat activity (2023)
Journal Article
Hooker, J., Daley, E., Stone, E., & Lintott, P. (2023). Assessing the impact of festival music on bat activity. Ecological Solutions and Evidence, 4(2), Article e12250. https://doi.org/10.1002/2688-8319.12250

Sound is a critical component of an animal's habitat, where it is used to glean important environmental information from their surroundings. The modification of natural soundscapes due to the global rise in anthropogenic noise pollution over recent d... Read More about Assessing the impact of festival music on bat activity.

Exploring the interaction between online practices and offline domestic food practices in family homes: Implications for food waste reduction campaigns (2023)
Thesis
Ridgway, A. Exploring the interaction between online practices and offline domestic food practices in family homes: Implications for food waste reduction campaigns. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/10307861

Food waste is a significant problem in the food system, contributing to the environmental impact of food production and distribution as well as food inequality. In the UK and other high-income countries, a high proportion of the food waste in the foo... Read More about Exploring the interaction between online practices and offline domestic food practices in family homes: Implications for food waste reduction campaigns.

The tree(s) of hope and ambition: An arts-based social science informed, participatory research method to explore children's future hopes, ambitions and support in relation to COVID-19 (2023)
Journal Article
Williams, S., McEwen, L. J., Gorell Barnes, L., Deave, T., Webber, A., Jones, V., …Hobbs, L. (2023). The tree(s) of hope and ambition: An arts-based social science informed, participatory research method to explore children's future hopes, ambitions and support in relation to COVID-19. Children & Society, 37(5), 1356-1375. https://doi.org/10.1111/chso.12767

This paper offers a new child-centred methodology that explores children's visions of their futures, encourages self-reflection and depth and shares children's voices with peers and researchers, as unbrokered as possible. This final stage of a longit... Read More about The tree(s) of hope and ambition: An arts-based social science informed, participatory research method to explore children's future hopes, ambitions and support in relation to COVID-19.

Competencies of the UK nursing and midwifery workforce to mainstream genomics in the National Health Service: The ongoing gap between perceived importance and confidence in genomics (2023)
Journal Article
Carpenter-Clawson, C., Watson, M., Pope, A., Lynch, K., Miles, T., Bell, D., …Varadi, A. (2023). Competencies of the UK nursing and midwifery workforce to mainstream genomics in the National Health Service: The ongoing gap between perceived importance and confidence in genomics. Frontiers in Genetics, 14, 1125599. https://doi.org/10.3389/fgene.2023.1125599

The United Kingdom is recognised worldwide as a leader in genomics. The use of genomic technologies in the National Health Service (NHS) is expected to deliver faster and more accurate diagnoses, supporting personalized treatments to improve patient... Read More about Competencies of the UK nursing and midwifery workforce to mainstream genomics in the National Health Service: The ongoing gap between perceived importance and confidence in genomics.

Amplifying the voices of neurodivergent students in relation to higher education assessment at UWE Bristol (2023)
Report
Chicken, S., Fogg Rogers, L., Hobbs, L., Hunt-Fraisse, T., & Lewis, D. (2023). Amplifying the voices of neurodivergent students in relation to higher education assessment at UWE Bristol. UWE Bristol

This paper reports on a study funded by the UWE Pedagogical Project fund in 2021-2022, which aimed to amplify the voices of neurodivergent (referred to as ‘ND’) students in relation to lived experiences of Higher Education (HE) assessment practices w... Read More about Amplifying the voices of neurodivergent students in relation to higher education assessment at UWE Bristol.

Will AI chatbots replace physicists? (2023)
Digital Artefact
Glester, A. (in press). Will AI chatbots replace physicists?. [Podcast]

When discussing the capabilities of the latest AI chatbots, a physicist may argue: “Okay, they’re impressive at regurgitating texts that sound increasingly human. But we physicists don’t have much to worry about. It will be ages before the bots learn... Read More about Will AI chatbots replace physicists?.

Graphene-based electrodes for monitoring of Estradiol (2023)
Journal Article
Musa, A. M., Kiely, J., Luxton, R., & Honeychurch, K. C. (2023). Graphene-based electrodes for monitoring of Estradiol. Chemosensors, 11(6), 337. https://doi.org/10.3390/chemosensors11060337

This study explores the potential use of graphene-based electrodes in the electrochemical determination of estradiol using amperometric techniques as a simple, enzyme-free approach. Graphene, a carbon-based nanomaterial, has been extensively investig... Read More about Graphene-based electrodes for monitoring of Estradiol.