All Outputs (56)

Molecular displacement approach for the electrochemical detection of protein-bound propofol (2024)
Journal Article

Propofol is one of the principal drugs used for the sedation of patients undergoing mechanical ventilation in intensive care units. The correct dosage of such sedative drugs is highly important, but current methods of determining infusion rates are l... Read More about Molecular displacement approach for the electrochemical detection of protein-bound propofol.

Interleukins in urine and blood as markers of infection and as risk factors for systemic conditions (2024)
Journal Article

Interleukins are a diverse group of cytokines that play a crucial role in controlling immune responses and have potential as biomarkers. This mini review evaluates 12 recent papers linking urinary interleukins to both urinary infection and systemic d... Read More about Interleukins in urine and blood as markers of infection and as risk factors for systemic conditions.

WATER'S SILENT HORMONE MONITORING: A novel electrochemical sensor for on-site detection of estradiol in water (2023)
Presentation / Conference Contribution

The supply of safe drinking water is paramount for the health and well-being of people across the globe. Environmental pollutants such as estradiol (E2) threaten water supplies. Estradiol contamination of water sources is a growing global concern tha... Read More about WATER'S SILENT HORMONE MONITORING: A novel electrochemical sensor for on-site detection of estradiol in water.

Graphene-based electrodes for monitoring of Estradiol (2023)
Journal Article

This study explores the potential use of graphene-based electrodes in the electrochemical determination of estradiol using amperometric techniques as a simple, enzyme-free approach. Graphene, a carbon-based nanomaterial, has been extensively investig... Read More about Graphene-based electrodes for monitoring of Estradiol.

Rapid detection of tetracycline residues at clinically relevant levels via a novel, inexpensive and analytically-sensitive magneto-immunoassay – A feasibility study (2023)
Journal Article

Expensive, time-consuming and labour-intensive solvent-extraction and liquid-chromatography methods are the industry's current gold standard for antibiotic residue quantification. A novel immunoassay methodology and system for the rapid detection of... Read More about Rapid detection of tetracycline residues at clinically relevant levels via a novel, inexpensive and analytically-sensitive magneto-immunoassay – A feasibility study.

A non-faradaic impedimetric biosensor for monitoring of caspase 9 in mammalian cell culture (2023)
Journal Article

Lower yields and poorer quality of biopharmaceutical products result from cell death in bioreactors. Such cell death is commonly associated with programmed cell death or apoptosis. During apoptosis, caspases are activated and cause a cascade of event... Read More about A non-faradaic impedimetric biosensor for monitoring of caspase 9 in mammalian cell culture.

An electrochemical screen-printed sensor based on gold-nanoparticle-decorated reduced graphene oxide–carbon nanotubes composites for the determination of 17-β estradiol (2023)
Journal Article

In this study, a screen-printed electrode (SPE) modified with gold-nanoparticle-decorated reduced graphene oxide–carbon nanotubes (rGO-AuNPs/CNT/SPE) was used for the determination of estradiol (E2). The AuNPs were produced through an eco-friendly me... Read More about An electrochemical screen-printed sensor based on gold-nanoparticle-decorated reduced graphene oxide–carbon nanotubes composites for the determination of 17-β estradiol.

Metal oxide decorated carbon nanocomposite electrodes for propofol monitoring (2022)
Journal Article

Despite the growing evidence of the benefits of total-intravenous anaesthesia using propofol compared to conventional volatile-based anaesthesia, both in terms of environmental impact and patient outcomes, the majority of administered general anaesth... Read More about Metal oxide decorated carbon nanocomposite electrodes for propofol monitoring.

Modeling peptide nucleic acid binding enthalpies using MM-GBSA (2022)
Journal Article

The binding enthalpies of peptide nucleic acid (PNA) homoduplexes were predicted using a molecular mechanics generalized Born surface area approach. Using the nucleic acid nearest-neighbor model, these were decomposed into sequence parameters which c... Read More about Modeling peptide nucleic acid binding enthalpies using MM-GBSA.

Modelling a dynamic magneto-agglutination bioassay (2022)
Journal Article

The process of developing an end-to-end model of a magneto-immunoassay is described, simulating the agglutination effect due to the specific binding of bacteria to paramagnetic particles. After establishing the properties of the dose-specific aggluti... Read More about Modelling a dynamic magneto-agglutination bioassay.

Equivalent circuit model of a non-faradaic impedimetric ZnO nano-crystal biosensor (2022)
Journal Article

This paper describes the development of an equivalent electrical circuit (EEC) model of a unique co-planar electrode PET-ZnO biosensor platform. This non-faradaic ZnO biosensor had a PET insulating layer between the electrodes and the active ZnO sens... Read More about Equivalent circuit model of a non-faradaic impedimetric ZnO nano-crystal biosensor.

Passive impedance sensing using a SAW resonator-coupled biosensor for zero-power wearable applications (2021)
Journal Article

A bio-sensing scheme, which acquires impedance information of a capacitive biosensor by using the reflected RF signal from a surface acoustic wave (SAW) resonator connected to the biosensor, is proposed. This technique requires no power to be supplie... Read More about Passive impedance sensing using a SAW resonator-coupled biosensor for zero-power wearable applications.

Cytochrome P450 2B6 amperometric biosensor for continuous monitoring of propofol (2021)
Journal Article

Despite the growing evidence of improved patient outcomes and of a substantially reduced environmental impact of propofol-based total intravenous anesthesia when compared to volatile-based techniques, the vast majority of general anesthetics still us... Read More about Cytochrome P450 2B6 amperometric biosensor for continuous monitoring of propofol.

Propofol detection for monitoring of intravenous anaesthesia: A review (2021)
Journal Article

This paper presents a review of established and emerging methods for detecting and quantifying the intravenous anaesthetic propofol in solution. There is growing evidence of numerous advantages of total intravenous anaesthesia using propofol compared... Read More about Propofol detection for monitoring of intravenous anaesthesia: A review.

Recent progress in screen-printed electrochemical sensors and biosensors for the detection of estrogens (2021)
Journal Article

Estrogens have become increasingly prevalent in environmental samples across the world, posing a serious threat to human health. They have received considerable public attention due to their harmful effect on the normal endocrine functions of humans... Read More about Recent progress in screen-printed electrochemical sensors and biosensors for the detection of estrogens.

Classification of the mechanism of toxicity as applied to human cell line ECV304 (2020)
Journal Article

© 2020 Informa UK Limited, trading as Taylor & Francis Group. The objective of this study was to identify the pattern of cytotoxicity testing of the human cell line ECV304 using three techniques of an ensemble learning algorithm (bagging, boosting... Read More about Classification of the mechanism of toxicity as applied to human cell line ECV304.

Nanoparticle-based 3D membrane for impedimetric biosensor applications (2020)
Journal Article

This paper reports on a comparison between nano-ZnO/CuO and nano-ZnO nitrocellulose membrane biosensors, both of which were fabricated using a simple and inexpensive sonication technique. To produce the nano-ZnO/CuO membranes, the technique involved... Read More about Nanoparticle-based 3D membrane for impedimetric biosensor applications.

Sensor (2020)
Patent

The present invention relates to detecting viral infections in plants, especially Cacao swollen-shoot virus (CSSV) infections. Recombinant viral coat protein antigens and binding reagents that specifically bind to thereto are provided together with a... Read More about Sensor.

A non-contact impedimetric biosensing system for classification of toxins associated with cytotoxicity testing (2020)
Journal Article

© 2019 We report on a novel impedance spectroscopy measurement and data analysis technique for cytotoxicity testing. The technique combines non-contact measurement with real-time impedance data analysis based on the toxin dose dependency of the outpu... Read More about A non-contact impedimetric biosensing system for classification of toxins associated with cytotoxicity testing.

Initial trail results of a magnetic biosensor for the rapid detection of Porcine Reproductive and Respiratory Virus (PRRSV) infection (2019)
Journal Article

© 2019 The resonant coil magnetometer quantifies paramagnetic particles (PMPs) and has been used to develop magneto-immunoassays in a range of formats. The advantage of magneto-immunoassays is that they are relatively inexpensive, portable, easy to p... Read More about Initial trail results of a magnetic biosensor for the rapid detection of Porcine Reproductive and Respiratory Virus (PRRSV) infection.