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Propofol detection for monitoring of intravenous anaesthesia: A review

Ferrier, David; Kiely, Janice; Luxton, Richard

Propofol detection for monitoring of intravenous anaesthesia: A review Thumbnail


Authors

David Ferrier David.Ferrier@uwe.ac.uk
Research Fellow- Biosensing/ Health Technology

Janice Kiely Janice.Kiely@uwe.ac.uk
Professor in Bio-electronics/Res In CoDi

Richard Luxton Richard.Luxton@uwe.ac.uk
Research Centre Director-IBST/Professor



Abstract

This paper presents a review of established and emerging methods for detecting and quantifying the intravenous anaesthetic propofol in solution. There is growing evidence of numerous advantages of total intravenous anaesthesia using propofol compared to conventional volatile-based anaesthesia, both in terms of patient outcomes and environmental impact. However, volatile-based anaesthesia still accounts for the vast majority of administered general anaesthetics, largely due to a lack of techniques for real-time monitoring of patient blood propofol concentration. Herein, propofol detection techniques that have been developed to date are reviewed alongside a discussion of remaining challenges.

Citation

Ferrier, D., Kiely, J., & Luxton, R. (2022). Propofol detection for monitoring of intravenous anaesthesia: A review. Journal of Clinical Monitoring and Computing, 36, 315-323. https://doi.org/10.1007/s10877-021-00738-5

Journal Article Type Review
Acceptance Date Jun 28, 2021
Online Publication Date Jul 2, 2021
Publication Date 2022-06
Deposit Date Jul 2, 2021
Publicly Available Date Mar 29, 2024
Journal Journal of Clinical Monitoring and Computing
Print ISSN 1387-1307
Electronic ISSN 1573-2614
Publisher Springer (part of Springer Nature)
Peer Reviewed Peer Reviewed
Volume 36
Pages 315-323
DOI https://doi.org/10.1007/s10877-021-00738-5
Keywords Propofol; 2,6-Diisopropylphenol; Real-time monitoring; Optical detection; Electrochemical detection
Public URL https://uwe-repository.worktribe.com/output/7503557
Publisher URL https://link.springer.com/article/10.1007/s10877-021-00738-5

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