Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system (2018)
Journal Article
Fox, B. G., Thorn, R. M., Anesio, A. M., Cox, T., Attridge, J. W., & Reynolds, D. M. (2019). Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system. Water, 11(1), Article 10. https://doi.org/10.3390/w11010010

© 2018 by the authors. Organic matter (OM) has an essential biogeochemical influence along the hydrological continuum and within aquatic ecosystems. Organic matter derived via microbial processes was investigated within a range of model freshwater sa... Read More about Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system.

MEF2A regulates mGluR-dependent AMPA receptor trafficking independently of Arc/Arg3.1 (2018)
Journal Article
Carmichael, R. E., Wilkinson, K. A., Craig, T. J., Ashby, M. C., & Henley, J. M. (2018). MEF2A regulates mGluR-dependent AMPA receptor trafficking independently of Arc/Arg3.1. Scientific Reports, 8(1), 5263. https://doi.org/10.1038/s41598-018-23440-0

© 2018 The Author(s). Differential trafficking of AMPA receptors (AMPARs) to and from the postsynaptic membrane is a key determinant of the strength of excitatory neurotransmission, and is thought to underlie learning and memory. The transcription fa... Read More about MEF2A regulates mGluR-dependent AMPA receptor trafficking independently of Arc/Arg3.1.

Facile and inexpensive fabrication of zinc oxide based bio-surfaces for C-reactive protein detection (2018)
Journal Article
Lu, C., Janice, K., Martina, P., & Richard, L. (2018). Facile and inexpensive fabrication of zinc oxide based bio-surfaces for C-reactive protein detection. Scientific Reports, 8(1), 122687. https://doi.org/10.1038/s41598-018-30793-z

© 2018, The Author(s). The paper reports a biosensor formed from antibody coated ZnO nano-crystals which has been prepared using a rapid and inexpensive fabrication method which utilises colloidal dispersion enhanced using sonication. This technique... Read More about Facile and inexpensive fabrication of zinc oxide based bio-surfaces for C-reactive protein detection.

Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa (2018)
Journal Article
Buskin, A., Zhu, L., Chichagova, V., Basu, B., Mozaffari-Jovin, S., Dolan, D., …Lako, M. (2018). Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa. Nature Communications, 9(1), 4234. https://doi.org/10.1038/s41467-018-06448-y

© 2018, The Author(s). Mutations in pre-mRNA processing factors (PRPFs) cause autosomal-dominant retinitis pigmentosa (RP), but it is unclear why mutations in ubiquitously expressed genes cause non-syndromic retinal disease. Here, we generate transcr... Read More about Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa.

Gas chromatography mass spectrometry (GC-MS) quantification of metabolites in stool using13 C labelled compounds (2018)
Journal Article
Gould, O., Costello, B. D. L., Smart, A., Jones, P., Macmaster, A., Ransley, K., & Ratcliffe, N. (2018). Gas chromatography mass spectrometry (GC-MS) quantification of metabolites in stool using13 C labelled compounds. Metabolites, 8(4), 75. https://doi.org/10.3390/metabo8040075

© 2018 by the authors. Licensee MDPI, Basel, Switzerland. It has become increasingly important to qualitatively and quantitatively assess the volatile metabolites in a range of bodily fluids for use in monitoring health. There has been relatively lit... Read More about Gas chromatography mass spectrometry (GC-MS) quantification of metabolites in stool using13 C labelled compounds.

Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O 6 -methylguanine in vivo (2018)
Journal Article
Kraus, A., McKeague, M., Seiwert, N., Nagel, G., Geisen, S. M., Ziegler, N., …Fahrer, J. (2019). Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O 6 -methylguanine in vivo. Archives of Toxicology, 93(2), 559-572. https://doi.org/10.1007/s00204-018-2355-0

© 2018, Springer-Verlag GmbH Germany, part of Springer Nature. N-nitroso compounds are alkylating agents, which are widespread in our diet and the environment. They induce DNA alkylation adducts such as O 6 -methylguanine (O 6 -MeG), which is repair... Read More about Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O 6 -methylguanine in vivo.

Community screening to determine the prevalence of carbapenemase producing organisms in East London, 2018 (2018)
Presentation / Conference
Henderson, J., Ciesielczuk, H., Nelson, S., & Wilks, M. (2018, November). Community screening to determine the prevalence of carbapenemase producing organisms in East London, 2018. Poster presented at Federation of Infection Sciences Conference 2018, Newcastle, England

Carbapenems are broad spectrum antibiotics reserved for patients who are extremely ill or suspected of having an infection caused by a multidrug resistant organism (Nordmann et al., 2011). Over the past ten years there has been a dramatic increase in... Read More about Community screening to determine the prevalence of carbapenemase producing organisms in East London, 2018.

Hydrogen gas, ROS metabolism and cell signaling: Are hydrogen spin states important? (2018)
Journal Article
Hancock, J. T., & Hancock, T. H. (2018). Hydrogen gas, ROS metabolism and cell signaling: Are hydrogen spin states important?. Reactive Oxygen Species, 6(18),

It is becoming accepted that treatment with hydrogen gas (H2) has profound and often beneficial effects on cells from both animals and plants. Future uses which have been suggested include for cancer treatment, for alleviating symptoms of Parkinson’s... Read More about Hydrogen gas, ROS metabolism and cell signaling: Are hydrogen spin states important?.

Antimicrobial activity of cinnamon essential oil and its effect against P.aeruginosa biofilms (2018)
Presentation / Conference
Elcocks, E., Spencer-Phillips, P., & Adukwu, E. (2018, October). Antimicrobial activity of cinnamon essential oil and its effect against P.aeruginosa biofilms. Poster presented at 8th Annual American Society for Microbiology (ASM) Biofilms Conference 2018, Washington DC

Parameterization of a coarse-grained model of cholesterol with point-dipole electrostatics (2018)
Journal Article
Paulo, S., Khandelia, H., Orsi, M., & Dias, L. G. (2018). Parameterization of a coarse-grained model of cholesterol with point-dipole electrostatics. Journal of Computer-Aided Molecular Design, 32(11), 1259-1271. https://doi.org/10.1007/s10822-018-0164-4

© 2018, Springer Nature Switzerland AG. We present a new coarse-grained (CG) model of cholesterol (CHOL) for the electrostatic-based ELBA force field. A distinguishing feature of our CHOL model is that the electrostatics is modeled by an explicit poi... Read More about Parameterization of a coarse-grained model of cholesterol with point-dipole electrostatics.

Comprehensive longitudinal microbiome analysis of the chicken cecum reveals a shift from competitive to environmental drivers and a window of opportunity for Campylobacter (2018)
Journal Article
Ijaz, U. Z., Sivaloganathan, L., McKenna, A., Richmond, A., Kelly, C., Linton, M., …Gundogdu, O. (2018). Comprehensive longitudinal microbiome analysis of the chicken cecum reveals a shift from competitive to environmental drivers and a window of opportunity for Campylobacter. Frontiers in Microbiology, 9(OCT), Article 2452. https://doi.org/10.3389/fmicb.2018.02452

Copyright © 2018 Ijaz, Sivaloganathan, McKenna, Richmond, Kelly, Linton, Stratakos, Lavery, Elmi, Wren, Dorrell, Corcionivoschi and Gundogdu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC B... Read More about Comprehensive longitudinal microbiome analysis of the chicken cecum reveals a shift from competitive to environmental drivers and a window of opportunity for Campylobacter.

Effects of lipid composition on membrane permeation (2018)
Journal Article
Palaiokostas, M., Ding, W., Shahane, G., & Orsi, M. (2018). Effects of lipid composition on membrane permeation. Soft Matter, 14(42), 8496-8508. https://doi.org/10.1039/c8sm01262h

© 2018 The Royal Society of Chemistry. Passive permeation through lipid membranes is an essential process in biology. In vivo membranes typically consist of mixtures of lamellar and nonlamellar lipids. Lamellar lipids are characterized by their tende... Read More about Effects of lipid composition on membrane permeation.

The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties (2018)
Journal Article
Jumbe, S., Porazinski, S., Oltean, S., Mansell, J., Vahabi, B., Wilson, I., & Ladomery, M. (2019). The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties. Translational Oncology, 12(1), 134-142. https://doi.org/10.1016/j.tranon.2018.09.001

© 2018 The oncogene ERG encodes an ETS family transcription factor and is implicated in blood, vascular, and bone development and in prostate, blood, and bone cancer. The ERG gene is alternatively spliced; of particular interest is its cassette exon... Read More about The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties.

Experimentally manipulating light spectra reveals the importance of dark corridors for commuting bats (2018)
Journal Article
Zeale, M. R. K., Stone, E. L., Zeale, E., Browne, W. J., Harris, S., & Jones, G. (2018). Experimentally manipulating light spectra reveals the importance of dark corridors for commuting bats. Global Change Biology, 24(12), 5909-5918. https://doi.org/10.1111/gcb.14462

© 2018 The Authors Global Change Biology Published by John Wiley & Sons Ltd The rapid global spread of artificial light at night is causing unprecedented disruption to ecosystems. In otherwise dark environments, street lights restrict the use of ma... Read More about Experimentally manipulating light spectra reveals the importance of dark corridors for commuting bats.

Association of single nucleotide polymorphisms in leptin (LEP) and leptin receptor (LEPR) genes with backfat thickness and daily weight gain in Ukrainian Large White pigs (2018)
Journal Article
Balatsky, V., Oliinychenko, Y., Sarantseva, N., Getya, A., Saienko, A., Vovk, V., & Doran, O. (2018). Association of single nucleotide polymorphisms in leptin (LEP) and leptin receptor (LEPR) genes with backfat thickness and daily weight gain in Ukrainian Large White pigs. Livestock Science, 217, 157-161. https://doi.org/10.1016/j.livsci.2018.09.015

© 2018 Elsevier B.V. Leptin (LEP) and leptin receptor (LEPR) genes play an important role in the regulation of fat deposition and other commercially important traits in pigs and this regulation is known to be breed-specific. The aim of the present st... Read More about Association of single nucleotide polymorphisms in leptin (LEP) and leptin receptor (LEPR) genes with backfat thickness and daily weight gain in Ukrainian Large White pigs.

A novel natural antimicrobial can reduce the in vitro and in vivo pathogenicity of T6SS positive Campylobacter jejuni and campylobacter coli chicken isolates (2018)
Journal Article
Sima, F., Stratakos, A. C., Ward, P., Linton, M., Kelly, C., Pinkerton, L., …Corcionivoschi, N. (2018). A novel natural antimicrobial can reduce the in vitro and in vivo pathogenicity of T6SS positive Campylobacter jejuni and campylobacter coli chicken isolates. Frontiers in Microbiology, 9, Article 2139. https://doi.org/10.3389/fmicb.2018.02139

© 2018 Sima, Stratakos, Ward, Linton, Kelly, Pinkerton, Stef, Gundogdu, Lazar and Corcionivoschi. Human campylobacteriosis is considered one of the most common foodborne diseases worldwide with poultry identified as the main source of infection accou... Read More about A novel natural antimicrobial can reduce the in vitro and in vivo pathogenicity of T6SS positive Campylobacter jejuni and campylobacter coli chicken isolates.

Hydrogen sulfide and environmental stresses (2018)
Journal Article
Hancock, J. T. (2019). Hydrogen sulfide and environmental stresses. Environmental and Experimental Botany, 161, 50-56. https://doi.org/10.1016/j.envexpbot.2018.08.034

© 2018 Elsevier B.V. Hydrogen sulfide (H 2 S) is part of a suite of small reactive molecules which are known to be involved in cell signaling events in plants. It is produced by cells, can move around, including through membranes, and can be removed... Read More about Hydrogen sulfide and environmental stresses.

An investigation into the function and regulation Of ERG Exon 7b (2018)
Thesis
Jumbe, S. An investigation into the function and regulation Of ERG Exon 7b. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/1494104

The ETS family transcription factor ERG is a key oncoprotein in bone, blood, vascular and most notably prostate cancer where it is activated in at least 50% of cases. Of the several splice isoforms of ERG with variable biological activity those that... Read More about An investigation into the function and regulation Of ERG Exon 7b.

Exploring population responses to environmental change when there is never enough data: a factor analytic approach (2018)
Journal Article
Hindle, B. J., Rees, M., Sheppard, A. W., Quintana-Ascencio, P. F., Menges, E. S., & Childs, D. Z. (2018). Exploring population responses to environmental change when there is never enough data: a factor analytic approach. Methods in Ecology and Evolution, 9(11), 2283-2293. https://doi.org/10.1111/2041-210X.13085

© 2018 The Authors. Methods in Ecology and Evolution published by John Wiley & Sons Ltd on behalf of British Ecological Society Temporal variability in the environment drives variation in vital rates, with consequences for population dynamics and l... Read More about Exploring population responses to environmental change when there is never enough data: a factor analytic approach.

Supercoiling of an excised genomic island represses effector gene expression to prevent activation of host resistance (2018)
Journal Article
Neale, H., Jackson, R., Preston, G., & Arnold, D. (2018). Supercoiling of an excised genomic island represses effector gene expression to prevent activation of host resistance. Molecular Microbiology, 110(3), 444-454. https://doi.org/10.1111/mmi.14111

© 2018 The Authors Molecular Microbiology Published by John Wiley & Sons Ltd. The plant pathogen Pseudomonas syringae pv. phaseolicola, which causes halo blight disease of beans, contains a 106kb genomic island PPHGI-1. PPHGI-1 carries a gene, avrP... Read More about Supercoiling of an excised genomic island represses effector gene expression to prevent activation of host resistance.