The development of novel fuel dehydrating icing inhibitors (2015)
Thesis
Repetto, S. L. The development of novel fuel dehydrating icing inhibitors. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/7512199

Dissolved water is a normal component of jet fuel which is vapourised during combustion; however, free water is a contaminant that can starve engines, freeze to form ice crystals capable of blocking fuel feeds, support microbial growth, and contribut... Read More about The development of novel fuel dehydrating icing inhibitors.

Fluorophosphonate-functionalised titanium via a pre-adsorbed alkane phosphonic acid: a novel dual action surface finish for bone regenerative applications (2015)
Journal Article
Ayre, W. N., Scott, T., Hallam, K., Blom, A. W., Denyer, S., Bone, H. K., & Mansell, J. P. (2016). Fluorophosphonate-functionalised titanium via a pre-adsorbed alkane phosphonic acid: a novel dual action surface finish for bone regenerative applications. Journal of Materials Science: Materials in Medicine, 27(2), Article 36. https://doi.org/10.1007/s10856-015-5644-7

© 2015, Springer Science+Business Media New York. Abstract: Enhancing vitamin D-induced human osteoblast (hOB) maturation at bone biomaterial surfaces is likely to improve prosthesis integration with resultant reductions in the need for revision art... Read More about Fluorophosphonate-functionalised titanium via a pre-adsorbed alkane phosphonic acid: a novel dual action surface finish for bone regenerative applications.

Environmental Plant Physiology (2015)
Book
Willey, N. (2015). Environmental Plant Physiology. New York: Garland Science

Environmental Plant Physiology focuses on the physiology of plant-environment interactions, revealing plants as the key terrestrial intersection of the biosphere, atmosphere, hydrosphere and geosphere. It provides a contemporary understanding of the... Read More about Environmental Plant Physiology.

Effects of Lipid Composition on Bilayer Membranes Quantified by All-Atom Molecular Dynamics (2015)
Journal Article
Ding, W., Palaiokostas, M., Wang, W., & Orsi, M. (2015). Effects of Lipid Composition on Bilayer Membranes Quantified by All-Atom Molecular Dynamics. Journal of Physical Chemistry B, 119(49), 15263-15274. https://doi.org/10.1021/acs.jpcb.5b06604

© 2015 American Chemical Society. Biological bilayer membranes typically contain varying amounts of lamellar and nonlamellar lipids. Lamellar lipids, such as dioleoylphosphatidylcholine (DOPC), are defined by their tendency to form the lamellar phase... Read More about Effects of Lipid Composition on Bilayer Membranes Quantified by All-Atom Molecular Dynamics.

The design, development and application of electrochemical glutamate biosensors (2015)
Journal Article
Hart, J. P., Pemberton, R. M., Hughes, G., Hughes, G., Pemberton, R., Fielden, P. R., & Hart, J. P. (2016). The design, development and application of electrochemical glutamate biosensors. Trends in Analytical Chemistry, 79, 106-113. https://doi.org/10.1016/j.trac.2015.10.020

© 2015 Elsevier B.V. The development of biosensors for the determination of glutamate has been of great research interest for the past 25 years due to its importance in biomedical and food studies. This review focusses on the various strategies used... Read More about The design, development and application of electrochemical glutamate biosensors.

SUMOylation of Syntaxin1A regulates presynaptic endocytosis (2015)
Journal Article
Henley, J. M., Craig, T. J., Anderson, D., Evans, A. J., & Girach, F. (2015). SUMOylation of Syntaxin1A regulates presynaptic endocytosis. Scientific Reports, 5, 17669. https://doi.org/10.1038/srep17669

Neurotransmitter release from the presynaptic terminal is under very precise spatial and temporal control. Following neurotransmitter release, synaptic vesicles are recycled by endocytosis and refilled with neurotransmitter. During the exocytosis eve... Read More about SUMOylation of Syntaxin1A regulates presynaptic endocytosis.

Gibbsiella papilionis Kim et al. 2013 is a later heterotypic synonym of gibbsiella dentisursi Saito et al. 2013 (2015)
Journal Article
Brady, C., Irisawa, T., Iino, T., Ohkuma, M., Arnold, D. L., & Denman, S. (2015). Gibbsiella papilionis Kim et al. 2013 is a later heterotypic synonym of gibbsiella dentisursi Saito et al. 2013. International Journal of Systematic and Evolutionary Microbiology, 65(12), 4788-4791. https://doi.org/10.1099/ijsem.0.000649

© 2015 IUMS. Synonymy of Gibbsiella dentisursi DSM 23818T (=NUM 1720T) and Gibbsiella papilionis JCM 18389T (=LEN33T) was suspected following multilocus sequence analysis (MLSA) of both type strains in a previous classification study, where they were... Read More about Gibbsiella papilionis Kim et al. 2013 is a later heterotypic synonym of gibbsiella dentisursi Saito et al. 2013.

Dual Action of lysophosphatidate- functionalised titanium: Interactions with human (MG63) osteoblasts and methicillin resistant staphylococcus aureus (2015)
Journal Article
Skindersoe, M. E., Krogfelt, K. A., Blom, A., Jiang, G., Prestwich, G. D., & Mansell, J. P. (2015). Dual Action of lysophosphatidate- functionalised titanium: Interactions with human (MG63) osteoblasts and methicillin resistant staphylococcus aureus. PLoS ONE, 10(11), Article e0143509. https://doi.org/10.1371/journal.pone.0143509

© 2015 Skindersoe et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are... Read More about Dual Action of lysophosphatidate- functionalised titanium: Interactions with human (MG63) osteoblasts and methicillin resistant staphylococcus aureus.

Design and application of liquid chromatography dual electrode detection (2015)
Book Chapter
Honeychurch, K. C. (2015). Design and application of liquid chromatography dual electrode detection. In C. Banks, R. Mortimer, & S. Mcintosh (Eds.), Specialist Periodical Reports (1-20). Cambridge: Royal Society of Chemistry. https://doi.org/10.1039/9781782620273

Liquid chromatography with electrochemical detection has been shown to be both highly sensitive and selective. Initially electrochemical detection in this approach has utilised single electrode based electrochemical detector systems, where the compou... Read More about Design and application of liquid chromatography dual electrode detection.

The Molecular Biology of RNA (2015)
Book
Elliott, D., & Ladomery, M. (2015). The Molecular Biology of RNA. Oxford: Oxford University Press

Inter-Taxa differences in iodine uptake by plants: Implications for food quality and contamination (2015)
Journal Article
Siasou, E., & Willey, N. (2015). Inter-Taxa differences in iodine uptake by plants: Implications for food quality and contamination. Agronomy, 5(4), 537-554. https://doi.org/10.3390/agronomy5040537

© 2015 by the authors. Although iodine is not essential for plants, they take it up readily and, in foodchains, are significant sources of iodine for organisms with an essential requirement for it. During several nuclear accidents radioiodine has bee... Read More about Inter-Taxa differences in iodine uptake by plants: Implications for food quality and contamination.

A novel biosensor for prediction of global hypomethylation by decitabine and azacytadine in leukaemic cells (2015)
Journal Article
May, J. E., Allainguillaume, J., Page, K., Stratford-Smith, C., Aruomaren, A., Alloush, H., …Anderson, E. (2015). A novel biosensor for prediction of global hypomethylation by decitabine and azacytadine in leukaemic cells. Mutagenesis, 30(6), 856. https://doi.org/10.1093/mutage/gev074

Decitabine (DAC) and azacytidine (AZA) are cytidine ana- logues and hypomethylating agents used in the manage- ment of patients with myelodysplastic syndrome (MDS), where the main goal is to prevent transformation to acute myeloid leukaemia (AML), wh... Read More about A novel biosensor for prediction of global hypomethylation by decitabine and azacytadine in leukaemic cells.

The stromal cell line HS-5 is an alternative mesenchymal stem cell source for the development of a 3D bone marrow model (2015)
Journal Article
Kabrah, S., May, J. E., Donaldson, C., & Morse, H. R. (2015). The stromal cell line HS-5 is an alternative mesenchymal stem cell source for the development of a 3D bone marrow model. Mutagenesis, 30(6), 861. https://doi.org/10.1093/mutage/gev074

Developing a novel three-dimensional (3D) in vitro model of the bone marrow microenvironment using bone mar- row mesenchymal stem cells (BM-MSCs) in commercial matrices involves a series of distinct processes. This starts with selecting an appropriat... Read More about The stromal cell line HS-5 is an alternative mesenchymal stem cell source for the development of a 3D bone marrow model.

Determination of the appropriate gene for real-time PCR analysis of the immotalized stromal cell line HS-5 in 2D and 3D culture following melphalan exposure (2015)
Journal Article
Kabrah, S., May, J. E., Donaldson, C., & Morse, H. R. (2015). Determination of the appropriate gene for real-time PCR analysis of the immotalized stromal cell line HS-5 in 2D and 3D culture following melphalan exposure. Mutagenesis, 30(6), 874. https://doi.org/10.1093/mutage/gev074

Although gene expression analysis using real-time quan- titative reverse transcription-polymerase chain reaction (RT-qPCR) is an accurate method to evaluate cell activi- ties and phenotypes, the reliability of the analysis depends on the selection of... Read More about Determination of the appropriate gene for real-time PCR analysis of the immotalized stromal cell line HS-5 in 2D and 3D culture following melphalan exposure.

Bone marrow and myeloma cellular communication protects from genotoxicity in a drug-specific manner (2015)
Journal Article
Andrews, S., Morse, H. R., & May, J. E. (2015). Bone marrow and myeloma cellular communication protects from genotoxicity in a drug-specific manner. Mutagenesis, 30(6), 867-868. https://doi.org/10.1093/mutage/gev074

Multiple myeloma (MM) is an incurable haematological malignancy with most patients eventually developing ad- vanced, relapsing disease and drug resistance (1,2). This may result from protection by BM mesenchymal cells (BM— MSC) interacting with MM ce... Read More about Bone marrow and myeloma cellular communication protects from genotoxicity in a drug-specific manner.

The design, development and application of novel, screen-printed amperometric glutamate biosensors (2015)
Thesis
Hughes, G. The design, development and application of novel, screen-printed amperometric glutamate biosensors. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/803754

The aim of the studies presented in this thesis was to develop a screen-printed electrochemical biosensor for the measurement of glutamate and to apply this device to the determination of the analyte in food, serum and toxicity studies. Chapter 1... Read More about The design, development and application of novel, screen-printed amperometric glutamate biosensors.

The Scd6/Lsm14 protein xRAPB has properties different from RAP55 in selecting mRNA for early translation or intracellular distribution in Xenopus oocytes (2015)
Journal Article
Ladomery, M., & Sommerville, J. (2015). The Scd6/Lsm14 protein xRAPB has properties different from RAP55 in selecting mRNA for early translation or intracellular distribution in Xenopus oocytes. BBA - Gene Regulatory Mechanisms, 1849(11), 1363-1373. https://doi.org/10.1016/j.bbagrm.2015.10.002

© 2015 Elsevier B.V. Oocytes accumulate mRNAs in the form of maternal ribonucleoprotein (RNP) particles, the protein components of which determine the location and stability of individual mRNAs prior to translation. Scd6/Lsm14 proteins, typified by R... Read More about The Scd6/Lsm14 protein xRAPB has properties different from RAP55 in selecting mRNA for early translation or intracellular distribution in Xenopus oocytes.

Hydrogen sulfide and reactive friends: The interplay with reactive oxygen species and nitric oxide signalling pathways (2015)
Book Chapter
Hancock, J. T., & Whiteman, M. (2015). Hydrogen sulfide and reactive friends: The interplay with reactive oxygen species and nitric oxide signalling pathways. In L. de Kok, M. Hawkesford, H. Rennenberg, & K. Saito (Eds.), Molecular Physiology and Ecophysiology of Sulfur (153-168). Springer. https://doi.org/10.1007/978-3-319-20137-5_16

Hydrogen sulfide (H2S) is now considered to be a signalling molecule in a range of organisms. In animals and plants there are characterised mechanisms for its generation and removal suggesting that it can be made and have an effect when required. In... Read More about Hydrogen sulfide and reactive friends: The interplay with reactive oxygen species and nitric oxide signalling pathways.

LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma (2015)
Journal Article
Vieira, G. C., Chockalingam, S., Melegh, Z., Greenhough, A., Malik, S., Szemes, M., …Malik, K. (2015). LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma. Oncotarget, 6(37), 40053-40067. https://doi.org/10.18632/oncotarget.5548

LGR5 is a marker of normal and cancer stem cells in various tissues where it functions as a receptor for R-spondins and increases canonical Wnt signalling amplitude. Here we report that LGR5 is also highly expressed in a subset of high grade neurobla... Read More about LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma.

Does sleep restriction make driving with distractions worse? A comparison of listening to the radio, texting, eating and drinking whilst on a short 10 minute drive (2015)
Presentation / Conference
Alford, C., Tombs, S., & Morgan, P. (2015, October). Does sleep restriction make driving with distractions worse? A comparison of listening to the radio, texting, eating and drinking whilst on a short 10 minute drive. Poster presented at British Sleep Society 2015 Conference, Gateshead, Newcastle