The design, development and application of electrochemical glutamate biosensors

Hughes, G.; Pemberton, R. M.; Hart, J. P.; Hughes, Gareth; Pemberton, Roy; Hart, John P.; Fielden, P. R.

Abstract

The development of biosensors for the determination of glutamate has been of great research interest for the past 25 years due to its importance in biomedical and food studies. This review focusses on the various strategies used to fabricate glutamate biosensors as well as their performance characteristics. A brief comparison of the enzyme immobilisation method employed and the performance characteristics of a range of glutamate biosensors are described in tabular form and then described in detail throughout the review: some selected examples have been included to demonstrate the various applications of these biosensors to real samples.

Citation

Hughes, G., Pemberton, R., Fielden, P., & Hart, J. P. (2016). The design, development and application of electrochemical glutamate biosensors. Trends in Analytical Chemistry, 79, 106-113. https://doi.org/10.1016/j.trac.2015.10.020

• Journal Article Type: Article
• Acceptance Date: Oct 6, 2015
• Online Publication Date: Dec 8, 2015
• Publication Date: Jan 1, 2016
• Journal: TrAC Trends in Analytical Chemistry
• Print ISSN: 0165-9936
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 79
• Pages: 106-113
• DOI: https://doi.org/10.1016/j.trac.2015.10.020
• Keywords: glutamate oxidase, glutamate dehydrogenase, monosodium glutamate, amperometry, carbon nanotubes, reagentless, biosensor, NADH, NAD+, differential pulse voltammetry
• Public URL: https://uwe-repository.worktribe.com/output/919903
• Publisher URL: http://dx.doi.org/10.1016/j.trac.2015.10.020