The design, development and application of electrochemical glutamate biosensors

Hughes, G.; Pemberton, R. M.; Hart, J. P.; Hughes, Gareth; Pemberton, Roy; Hart, John P.; Fielden, P. R.

Abstract

© 2015 Elsevier B.V. The development of biosensors for the determination of glutamate has been of great research interest for the past 25 years due to its importance in biomedical and food studies. This review focusses on the various strategies used to fabricate glutamate biosensors as well as their performance characteristics. A brief comparison of the enzyme immobilisation method employed and the performance characteristics of a range of glutamate biosensors are described in tabular form and then described in detail throughout the review: some selected examples have been included to demonstrate the various applications of these biosensors to real samples.

• Journal Article Type: Review
• Acceptance Date: Oct 6, 2015
• Online Publication Date: Dec 8, 2015
• Publication Date: May 1, 2016
• Deposit Date: Apr 4, 2016
• Publicly Available Date: Dec 8, 2016
• Journal: TrAC - Trends in Analytical Chemistry
• Print ISSN: 0165-9936
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 79
• Pages: 106-113
• DOI: https://doi.org/10.1016/j.trac.2015.10.020
• Keywords: glutamate oxidase, glutamate dehydrogenase, monosodium glutamate, amperometry, carbon nanotubes, reagentless, biosensor, NADH, NAD+, differential pulse voltammetry
• Public URL: https://uwe-repository.worktribe.com/output/919903
• Publisher URL: http://dx.doi.org/10.1016/j.trac.2015.10.020
• Contract Date: Apr 4, 2016