Use of illness severity scores to predict mortality in interstitial lung disease patients hospitalised with acute respiratory deterioration (2023)
Journal Article
Williams, R. L., Hyams, C., Robertshaw, J., Garcia Gonzalez, M., Szasz-Benczur, Z., White, P., … Barratt, S. L. (2023). Use of illness severity scores to predict mortality in interstitial lung disease patients hospitalised with acute respiratory deterioration. Respiratory Medicine, 212, 107220. https://doi.org/10.1016/j.rmed.2023.107220

Introduction: Hospitalisations relating to acute respiratory deteriorations (ARD) in Interstitial Lung Disease (ILD) have poor outcomes. Factors predicting adverse outcomes are not fully understood and data addressing the use of illness severity scor... Read More about Use of illness severity scores to predict mortality in interstitial lung disease patients hospitalised with acute respiratory deterioration.

Strengthening management, community engagement, and sustainability of the subnational response to accelerate malaria elimination in Namibia (2022)
Journal Article
Chung, A. M., Love, E., Neidel, J., Mendai, I., Nairenge, S., van Wyk, L. A., …Gosling, R. (2022). Strengthening management, community engagement, and sustainability of the subnational response to accelerate malaria elimination in Namibia. American Journal of Tropical Medicine and Hygiene, 106(6), 1646-1652. https://doi.org/10.4269/ajtmh.21-1195

Leadership and management skills are critical for health programs to deliver high-quality interventions in complex systems. In malaria-eliminating countries, national and subnational health teams are reorienting strategies to address focal transmissi... Read More about Strengthening management, community engagement, and sustainability of the subnational response to accelerate malaria elimination in Namibia.

Early determinants of mortality in hospitalized COVID-19 patients in the Eastern Province of Saudi Arabia (2022)
Journal Article
Ansari, K. A., Alwazzeh, M. J., Alkuwaiti, F. A., Farooqi, F. A., Al Khathlan, N., Almutawah, H., …Alkuwaiti, E. (2022). Early determinants of mortality in hospitalized COVID-19 patients in the Eastern Province of Saudi Arabia. International Journal of General Medicine, 15(15), 1689-1701. https://doi.org/10.2147/ijgm.s349598

Purpose: This study investigated the clinical determinants of mortality in hospitalized patients infected with COVID-19. Patients and Methods: A retrospective multicenter large cohort of COVID-19 patients hospitalized between March 2020 and February... Read More about Early determinants of mortality in hospitalized COVID-19 patients in the Eastern Province of Saudi Arabia.

An on-premise study to investigate the effects of mixing alcohol with caffeinated beverages (2022)
Journal Article
Johnson, S. J., Verster, J. C., & Alford, C. (2022). An on-premise study to investigate the effects of mixing alcohol with caffeinated beverages. Brain and Behavior, 12(3), Article e2445. https://doi.org/10.1002/brb3.2445

Objective: The purpose of this on-premise study was to determine if mixing alcohol with caffeinated mixers had an impact on objective and subjective intoxication. Methods: The study was conducted across eight drinking occasions in the City of Bristol... Read More about An on-premise study to investigate the effects of mixing alcohol with caffeinated beverages.

A comparison between ecological momentary assessment and the adapted-quick drinking screen: Alcohol mixed with energy drinks (2022)
Journal Article
Johnson, S. J., Verster, J. C., & Alford, C. (2022). A comparison between ecological momentary assessment and the adapted-quick drinking screen: Alcohol mixed with energy drinks. Alcohol and Alcoholism, 57(5), 630-640. https://doi.org/10.1093/alcalc/agab086

AIMS: To compare alcohol consumption and risk-taking behaviours on alcohol mixed with energy drink (AMED) and alcohol-only (AO) drinking occasions collected via ecological momentary assessment (EMA) versus retrospective survey methods (adapted-Quick... Read More about A comparison between ecological momentary assessment and the adapted-quick drinking screen: Alcohol mixed with energy drinks.

Accelerometers-embedded Lycra sleeves to test wear compliance and upper limb activity in people with stroke: A feasibility study (2021)
Journal Article
Kumar, P., Brodie, S., Molton, J., O'Reilly, R., Steele, J., Pearce, A., …Caleb-Solly, P. (2023). Accelerometers-embedded Lycra sleeves to test wear compliance and upper limb activity in people with stroke: A feasibility study. Journal of Prosthetics and Orthotics, 35(2), 122-128. https://doi.org/10.1097/JPO.0000000000000406

Introduction To establish a possible effect of Lycra sleeves, accurate recording of wear time is critical. The aim of this study was to test whether an accelerometer-embedded Lycra sleeve can measure wear compliance and record upper-limb (UL) movemen... Read More about Accelerometers-embedded Lycra sleeves to test wear compliance and upper limb activity in people with stroke: A feasibility study.

Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected (2021)
Journal Article
Gynn, L. E., Anderson, E., Robinson, G., Wexler, S. A., Upstill-Goddard, G., Cox, C., & May, J. E. (2021). Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected. Mutagenesis, 36(6), 419-428. https://doi.org/10.1093/mutage/geab033

Tumour microenvironments are hallmarked in many cancer types. In haematological malignancies, bone marrow (BM) mesenchymal stromal cells (MSC) protect malignant cells from drug-induced cytotoxicity. However, less is known about malignant impact on su... Read More about Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected.

Propofol detection for monitoring of intravenous anaesthesia: A review (2021)
Journal Article
Ferrier, D., Kiely, J., & Luxton, R. (2022). Propofol detection for monitoring of intravenous anaesthesia: A review. Journal of Clinical Monitoring and Computing, 36, 315-323. https://doi.org/10.1007/s10877-021-00738-5

This paper presents a review of established and emerging methods for detecting and quantifying the intravenous anaesthetic propofol in solution. There is growing evidence of numerous advantages of total intravenous anaesthesia using propofol compared... Read More about Propofol detection for monitoring of intravenous anaesthesia: A review.

Visual illusions modulate body perception disturbance and pain in Complex Regional Pain Syndrome: A randomized trial (2021)
Journal Article
Lewis, J. S., Newport, R., Taylor, G., Smith, M., & McCabe, C. S. (2021). Visual illusions modulate body perception disturbance and pain in Complex Regional Pain Syndrome: A randomized trial. European Journal of Pain, 25(7), 1551-1563. https://doi.org/10.1002/ejp.1766

Background: Effective treatment of longstanding Complex Regional Pain Syndrome (CRPS) is a challenge, as causal mechanisms remain elusive. People with CRPS frequently report distorted subjective perceptions of their affected limb. Evidence of pain re... Read More about Visual illusions modulate body perception disturbance and pain in Complex Regional Pain Syndrome: A randomized trial.

Patient reported outcomes in large vessel vasculitides (2021)
Journal Article
Robson, J., Mackie, S., & Hill, C. (2021). Patient reported outcomes in large vessel vasculitides. Current Rheumatology Reports, 23(2), Article 7. https://doi.org/10.1007/s11926-020-00979-4

Purpose of Review: The goal of this paper is to review current and future uses of patient-reported outcomes in large vessel vasculitis. The large vessel vasculitides comprise Giant Cell Arteritis and Takayasu arteritis; both are types of systemic vas... Read More about Patient reported outcomes in large vessel vasculitides.

A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer (2020)
Journal Article
Nounu, A., Greenhough, A., Heesom, K. J., Richmond, R. C., Zheng, J., Weinstein, S. J., …Relton, C. L. (2021). A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer. Cancer Epidemiology, Biomarkers and Prevention, 30(3), 564-575. https://doi.org/10.1158/1055-9965.EPI-20-1176

Background: Evidence for aspirin’s chemopreventative properties on colorectal cancer (CRC) is substantial, but its mechanism of action is not well-understood. We combined a proteomic approach with Mendelian randomization (MR) to identify possible new... Read More about A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer.

Novel method for the measurement of erythrocyte acetylcholinesterase activity in the Yt blood group system using amperometry in conjunction with screen-printed carbon electrodes (2020)
Journal Article
Crew, A., Karamatic Crew, V., Bagelow, L., Walser, P., Thornton, N., & Hart, J. (2020). Novel method for the measurement of erythrocyte acetylcholinesterase activity in the Yt blood group system using amperometry in conjunction with screen-printed carbon electrodes. Vox Sanguinis, 115(S1), 271-271. https://doi.org/10.1111/vox.13031

Background: The five antigens of the Yt blood group system are located on the membrane GPI‐linked erythrocyte acetylcholinesterase (AChE‐E), which is implicated in a range of clinical issues, including sleep apnoea and neurotoxin poisoning. Conformat... Read More about Novel method for the measurement of erythrocyte acetylcholinesterase activity in the Yt blood group system using amperometry in conjunction with screen-printed carbon electrodes.

The use of tissue adhesive as an adjunct to wound closure in knee arthroplasty does not reduce wound ooze (2020)
Journal Article
Khalefa, M. A., Smith, L. K., & Ahmad, R. (2020). The use of tissue adhesive as an adjunct to wound closure in knee arthroplasty does not reduce wound ooze. Knee Surgery & Related Research, 32(1), Article 57. https://doi.org/10.1186/s43019-020-00073-0

Introduction Persistent wound ooze has been associated with prolonged length of hospital stay and increased risk of infection. Recently, the use of tissue adhesive after hip and knee arthroplasty has been described. We believe that knee arthroplasty... Read More about The use of tissue adhesive as an adjunct to wound closure in knee arthroplasty does not reduce wound ooze.

Daily medical liaison is associated with reduced length of stay and complications in selected patients admitted to a regional vascular surgery service (2020)
Journal Article
Mitchell, E., Coary, R., White, P., Farrow, E., Crees, A., Beedham, W., …Shipway, D. (2020). Daily medical liaison is associated with reduced length of stay and complications in selected patients admitted to a regional vascular surgery service. Geriatrics, 5(4), Article 78. https://doi.org/10.3390/geriatrics5040078

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Older adults undergoing vascular surgery are particularly vulnerable to adverse outcomes by virtue of their vascular risk factors and medical comorbidities. This study aimed to determine the i... Read More about Daily medical liaison is associated with reduced length of stay and complications in selected patients admitted to a regional vascular surgery service.

Laboratory evaluation of the Sigma Transwab® transport system for the recovery of Candida species using the Clinical and Laboratory Standards Institute (CLSI) document M40-A2 (2020)
Journal Article
Adukwu, E., & Elcocks, E. (2021). Laboratory evaluation of the Sigma Transwab® transport system for the recovery of Candida species using the Clinical and Laboratory Standards Institute (CLSI) document M40-A2. European Journal of Clinical Microbiology and Infectious Diseases, 40, 735-738. https://doi.org/10.1007/s10096-020-04062-9

Rising healthcare complications due to fungal infections increase the importance of efficient specimen collection and maintenance systems for correct identification and diagnosis. The CLSI M40-A2 protocol provides guidelines for laboratories assessin... Read More about Laboratory evaluation of the Sigma Transwab® transport system for the recovery of Candida species using the Clinical and Laboratory Standards Institute (CLSI) document M40-A2.

Giving a voice to patient experiences through the insights of pragmatism (2020)
Journal Article
Deering, K., Williams, J., Stayner, K., & Pawson, C. (2021). Giving a voice to patient experiences through the insights of pragmatism. Nursing Philosophy, 22(1), Article e12329. https://doi.org/10.1111/nup.12329

As a philosophical position, pragmatism can be critiqued to distinguish truth only with methods that bring about desired results, predominantly with scientific enquiry. The article hopes to dismiss this oversimplification and propose that within ment... Read More about Giving a voice to patient experiences through the insights of pragmatism.

In vitro antifungal activity of Cinnamomum zeylanicum bark and leaf essential oils against Candida albicans and Candida auris (2020)
Journal Article
Tran, H. N. H., Graham, L., & Adukwu, E. C. (2020). In vitro antifungal activity of Cinnamomum zeylanicum bark and leaf essential oils against Candida albicans and Candida auris. Applied Microbiology and Biotechnology, 104, 8911–8924. https://doi.org/10.1007/s00253-020-10829-z

Candida infections are a significant source of patient morbidity and mortality. Candida albicans is the most common pathogen causing Candida infections. Candida auris is a newly described pathogen that is associated with multi-drug-resistant candidia... Read More about In vitro antifungal activity of Cinnamomum zeylanicum bark and leaf essential oils against Candida albicans and Candida auris.

Effect of novel technology-enabled multidimensional physical activity feedback in primary care patients at risk of chronic disease – the MIPACT study: A randomised controlled trial (2020)
Journal Article
Peacock, O. J., Western, M. J., Batterham, A. M., Chowdhury, E. A., Stathi, A., Standage, M., …Thompson, D. (2020). Effect of novel technology-enabled multidimensional physical activity feedback in primary care patients at risk of chronic disease – the MIPACT study: A randomised controlled trial. International Journal of Behavioral Nutrition and Physical Activity, 17, Article 99. https://doi.org/10.1186/s12966-020-00998-5

© 2020 The Author(s). Background: Technological progress has enabled the provision of personalised feedback across multiple dimensions of physical activity that are important for health. Whether this multidimensional approach supports physical activi... Read More about Effect of novel technology-enabled multidimensional physical activity feedback in primary care patients at risk of chronic disease – the MIPACT study: A randomised controlled trial.

An overview of SARS-CoV-2 (COVID-19) infection and the importance of molecular hydrogen as an adjunctive therapy (2020)
Journal Article
Russell, G., Rehman, M., LeBaron, T. W., Veal, D., Adukwu, E., & Hancock, J. (2020). An overview of SARS-CoV-2 (COVID-19) infection and the importance of molecular hydrogen as an adjunctive therapy. Reactive Oxygen Species, 10(28), 150–165

SARS-CoV-2 is an emerging β-coronavirus that causes COVID-19 disease that manifests primarily as a pulmonary infection that can rapidly progress into severe and acute respiratory distress in susceptible patients. Initial reports of severe pulmonary i... Read More about An overview of SARS-CoV-2 (COVID-19) infection and the importance of molecular hydrogen as an adjunctive therapy.

Global community child health (2020)
Journal Article
Ellis, M., & Pant, P. R. (2020). Global community child health. International Journal of Environmental Research and Public Health, 17(9), 3331. https://doi.org/10.3390/ijerph17093331

This special issue of IJERPH has published a range of studies in this developing field of Global Community Child Health research. A number of manuscripts submitted in response to our invitation describing ‘community-based interventions which impact o... Read More about Global community child health.