Skip to main content

Research Repository

Advanced Search

An overview of SARS-CoV-2 (COVID-19) infection and the importance of molecular hydrogen as an adjunctive therapy

Russell, Grace; Rehman, Mubasher; LeBaron, Tyler W.; Veal, David; Adukwu, Emmanuel; Hancock, John

An overview of SARS-CoV-2 (COVID-19) infection and the importance of molecular hydrogen as an adjunctive therapy Thumbnail


Authors

Grace Russell

Mubasher Rehman

Tyler W. LeBaron



Abstract

SARS-CoV-2 is an emerging β-coronavirus that causes COVID-19 disease that manifests primarily as a pulmonary infection that can rapidly progress into severe and acute respiratory distress in susceptible patients. Initial reports of severe pulmonary infections first arose in December 2019 and were reported to the World Health Organization by the Wuhan Municipal Health Commission, China. Within months SARS-CoV-2 rapidly disseminated across the globe causing an unprecedented pandemic that has reached every inhabited continent and provoked an international response into research involving multiple disciplines to combat this novel contagion. Molecular hydrogen (H2) has shown potential as an emerging and effective therapy for numerous diseases, particularly those which involve excessive production of inflammatory agents as well as reactive oxygen/nitrogen species. Of pertinence to the investigations of SARS-CoV-2 infection are the increasing reports that suggest that H2 has therapeutic qualities in the treatment of chronic inflammatory lung conditions, and as such it is likely that this diatomic gas may alleviate the severe pulmonary symptoms of COVID-19. Here, the aim is to review the current research into SARS-CoV-2 and to better understand how treatment with molecular hydrogen is likely to affect cellular responses during SARS-CoV-2 infection.

Citation

Russell, G., Rehman, M., LeBaron, T. W., Veal, D., Adukwu, E., & Hancock, J. (2020). An overview of SARS-CoV-2 (COVID-19) infection and the importance of molecular hydrogen as an adjunctive therapy. Reactive Oxygen Species, 10(28), 150–165

Journal Article Type Review
Acceptance Date Jun 20, 2020
Online Publication Date Jul 1, 2020
Publication Date Jul 1, 2020
Deposit Date Jun 21, 2020
Publicly Available Date Aug 2, 2020
Journal Reactive Oxygen Species
Print ISSN 2380-2367
Publisher AIMSCI Cell Med Press
Peer Reviewed Peer Reviewed
Volume 10
Issue 28
Pages 150–165
Keywords COVID-19; SARS-CoV-2; Cytokine Storm; Molecular Hydrogen; Reactive Oxygen Species; Virus
Public URL https://uwe-repository.worktribe.com/output/6050001
Publisher URL https://aimsci.com/ros/index.php/ros/article/view/271

Files








You might also like



Downloadable Citations