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Cloning and mapping of the porcine cytochrome-p450 2E1 gene and its association with skatole levels in the domestic pig (2005)
Journal Article
McGivan, J. D., Skinner, T. M., Doran (nee Udovikova), O., Haley, C. S., & Archibald, A. L. (2005). Cloning and mapping of the porcine cytochrome-p450 2E1 gene and its association with skatole levels in the domestic pig. Animal Genetics, 36(5), 417-422. https://doi.org/10.1111/j.1365-2052.2005.01342.x

The porcine cytochrome-p450 2E1 (CYP2E1) gene was isolated by screening a pig BAC library and partially sequenced. This sequence information was used to identify six single nucleotide polymorphisms (SNPs) within the CYP2E1 gene and its promoter. In a... Read More about Cloning and mapping of the porcine cytochrome-p450 2E1 gene and its association with skatole levels in the domestic pig.

Species selection for phytoremediation of 36Cl/35Cl using angiosperm phylogeny and inter-taxa differences in uptake (2005)
Journal Article
Willey, N., & Fawcett, K. (2005). Species selection for phytoremediation of 36Cl/35Cl using angiosperm phylogeny and inter-taxa differences in uptake. International Journal of Phytoremediation, 7(4), 295-306. https://doi.org/10.1080/16226510500327152

High concentrations of 35Cl and the radioisotope 36Cl (produced naturally by cosmic radiation and anthropogenically by U fission and the use of neutron sources) can be problematic in soil, but are potentially amenable to phytoremediation if appropria... Read More about Species selection for phytoremediation of 36Cl/35Cl using angiosperm phylogeny and inter-taxa differences in uptake.

Proteomic identification of glyceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis (2005)
Journal Article
Harrison, J., Hancock, J. T., Henson, D., Nyirenda, M., Desikan, R., Lewis, M., …Neill, S. (2005). Proteomic identification of glyceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis. Plant Physiology and Biochemistry, 43(9), 828-835. https://doi.org/10.1016/j.plaphy.2005.07.012

Hydrogen peroxide (H2O2) is now recognised as a key signalling molecule in eukaryotes. In plants, H2O2 is involved in regulating stomatal closure, gravitropic responses, gene expression and programmed cell death. Although several kinases, such as oxi... Read More about Proteomic identification of glyceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis.

A fantastic voyage: the making of news on nano-medicine (2005)
Presentation / Conference
Petersen, A., Allan, S., Anderson, A., & Wilkinson, C. (2005, September). A fantastic voyage: the making of news on nano-medicine. Paper presented at BSA Medical Sociology Group Annual Conference, York, England

Predicting inter-taxa differences in plant uptake of cesium-134/137 (2005)
Journal Article
Willey, N., Tang, S., & Watt, N. R. (2005). Predicting inter-taxa differences in plant uptake of cesium-134/137. Journal of Environmental Quality, 34(5), 1478-1489. https://doi.org/10.2134/jeq2004.0454

For 134/137Cs, and many other soil contaminants, research into transfer to plants has focused on particular crops and phytoremediation candidates, producing uptake data for a small proportion of all plant taxa. Despite the significance of differences... Read More about Predicting inter-taxa differences in plant uptake of cesium-134/137.

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: A possible role for cyclooxygenase 2 (2005)
Journal Article
Patsos, H. A., Hicks, D. J., Dobson, R. R., Greenhough, A., Woodman, N., Lane, J. D., …Paraskeva, C. (2005). The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: A possible role for cyclooxygenase 2. Gut, 54(12), 1741-1750. https://doi.org/10.1136/gut.2005.073403

Background and aims: Cyclooxygenase 2 (COX-2) is upregulated in most colorectal cancers and is responsible for metabolism of the endogenous cannabinoid, anandamide, into prostaglandin-ethanolamides (PG-EAs). The aims of this study were to determine w... Read More about The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: A possible role for cyclooxygenase 2.

Cannabinoids and cancer: Potential for colorectal cancer therapy (2005)
Journal Article
Patsos, H. A., Hicks, D. J., Greenhough, A., Williams, A. C., & Paraskeva, C. (2005). Cannabinoids and cancer: Potential for colorectal cancer therapy. Biochemical Society Transactions, 33(4), 712-714. https://doi.org/10.1042/BST0330712

Despite extensive research into the biology of CRC (colorectal cancer), and recent advances in surgical techniques and chemotherapy, CRC continues to be a major cause of death throughout the world. Therefore it is important to develop novel chemoprev... Read More about Cannabinoids and cancer: Potential for colorectal cancer therapy.

Experimental implementation of collision-based gates in Belousov-Zhabotinsky medium (2005)
Journal Article
de Lacy Costello, B., & Adamatzky, A. (2005). Experimental implementation of collision-based gates in Belousov-Zhabotinsky medium. Chaos, Solitons and Fractals, 25(3), 535-544. https://doi.org/10.1016/j.chaos.2004.11.056

We experimentally demonstrate that excitation wave-fragments in a Belousov-Zhabotinsky (BZ) medium with immobilised catalyst can be used to build elementary logical gates and circuits. Following our previous theoretical constructions [Adamatzky A. Co... Read More about Experimental implementation of collision-based gates in Belousov-Zhabotinsky medium.

Framing environmental risk: UK press reporting on nanotechnology (2005)
Presentation / Conference
Anderson, A., Allan, S., Petersen, A., & Wilkinson, C. (2005, July). Framing environmental risk: UK press reporting on nanotechnology. Paper presented at International Sociological Association Conference on Environment, Knowledge and Democracy, Marseille, France

Cruciate ligament laxity and femoral intercondylar notch narrowing in early-stage knee osteoarthritis (2005)
Journal Article
Quasnichka, H. L., Anderson-MacKenzie, J. M., Tarlton, J. F., Sims, T. J., Billingham, M. E. J., & Bailey, A. J. (2005). Cruciate ligament laxity and femoral intercondylar notch narrowing in early-stage knee osteoarthritis. Arthritis and Rheumatism, 52(10), 3100-3109. https://doi.org/10.1002/art.21340

Objective. The influence of the cruciate ligaments in spontaneous osteoarthritis (OA) is not understood, although ligament rupture is known to cause secondary OA. Additionally, femoral notch narrowing at the anterior cruciate ligament (ACL) insertion... Read More about Cruciate ligament laxity and femoral intercondylar notch narrowing in early-stage knee osteoarthritis.

Reactive oxygen species as signalling molecules (2005)
Book Chapter
Desikan, R., Hancock, J. T., & Neill, S. (2005). Reactive oxygen species as signalling molecules. In N. Smirnoff (Ed.), Antioxidants and Reactive Oxygen Species in Plants. Wiley

Study of overloading of basic drugs and peptides in reversed-phase high-performance liquid chromatography using pH adjustment of weak acid mobile phases suitable for mass spectrometry (2005)
Journal Article
McCalley, D. V. (2005). Study of overloading of basic drugs and peptides in reversed-phase high-performance liquid chromatography using pH adjustment of weak acid mobile phases suitable for mass spectrometry. Journal of Chromatography A, 1075(1-2), 57-64. https://doi.org/10.1016/j.chroma.2005.02.090

Serious losses in column efficiency for ionised basic drugs and peptides occur due to overloading of C18 phases when weak acid mobile phases of low ionic strength suitable for mass spectrometric detection are used. Measurable changes in retention tim... Read More about Study of overloading of basic drugs and peptides in reversed-phase high-performance liquid chromatography using pH adjustment of weak acid mobile phases suitable for mass spectrometry.

Rapid diagnosis of gastro-intestinal infections using faecal odour (2005)
Book Chapter
de Lacy Costello, B., Ewen, R., Garner, K., Probert, C., Ratcliffe, N. M., & Smith, S. (2005). Rapid diagnosis of gastro-intestinal infections using faecal odour. In A. Amann, & D. Smith (Eds.), Breath Analysis For Clinical Diagnosis And Therapeutic Monitoring (429-436). World Scientific Publishing Company

This book describes how the analysis of the trace gases in exhaled breath can be used for non-invasive clinical diagnosis of disease and for monitoring the effectiveness of therapy. This approach offers an important addition to the diagnostic techniq... Read More about Rapid diagnosis of gastro-intestinal infections using faecal odour.

Consultation for local air quality management in the UK: Barriers to successful science communication of local authority interaction with its stakeholders (2005)
Presentation / Conference
Dorfman, P., Beattie, C., Burnet, F., Gibbs, D., Longhurst, J., Weitkamp, E., & Leksmono, N. (2005, May). Consultation for local air quality management in the UK: Barriers to successful science communication of local authority interaction with its stakeholders. Presented at 13th International Conference on Modelling, Monitoring and Management of Air Pollution,, Cordoba, Spain

Voltammetric determination of urinary 1-hydroxypyrene using molecularly imprinted polymer-modified screen-printed carbon electrodes (2005)
Journal Article
Kirsch, N., Honeychurch, K. C., Hart, J. P., & Whitcombe, M. J. (2005). Voltammetric determination of urinary 1-hydroxypyrene using molecularly imprinted polymer-modified screen-printed carbon electrodes. Electroanalysis, 17(7), 571-578. https://doi.org/10.1002/elan.200403131

A two step non-competitive affinity method for the trace determination of 1-hydroxypyrene (1-OHP) using a disposable molecularly imprinted polymer (MIP) modified screen-printed carbon electrode (MIP-SPCE) has been developed. The MIP was synthesized a... Read More about Voltammetric determination of urinary 1-hydroxypyrene using molecularly imprinted polymer-modified screen-printed carbon electrodes.

Double-diffusive convection in a porous medium with a concentration based internal heat source (2005)
Journal Article
Hill, A. A. (2005). Double-diffusive convection in a porous medium with a concentration based internal heat source. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 461(2054), 561-574. https://doi.org/10.1098/rspa.2004.1328

Linear and nonlinear stability analyses of double-diffusive convection in a fluid-saturated porous layer with a concentration based internal heat source are studied. Darcy's law and the Boussinesq approximation are employed, with the equation of stat... Read More about Double-diffusive convection in a porous medium with a concentration based internal heat source.