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Cannabinoids and cancer: Potential for colorectal cancer therapy

Patsos, Helena A; Hicks, Diane J; Williams, Ann C; Paraskeva, Chris; Greenhough, A.


Helena A Patsos

Diane J Hicks

Ann C Williams

Chris Paraskeva


Despite extensive research into the biology of CRC (colorectal cancer), and recent advances in surgical techniques and chemotherapy, CRC continues to be a major cause of death throughout the world. Therefore it is important to develop novel chemopreventive/chemotherapeutic agents for CRC. Cannabinoids are a class of compounds that are currently used in the treatment of chemotherapy-induced nausea and vomiting, and in the stimulation of appetite. However, there is accumulating evidence that they could also be useful for the inhibition of tumour cell growth by modulating key survival signalling pathways. The chemotherapeutic potential for plant-derived and endogenous cannabinoids in CRC therapy is reviewed. ©2005 Biochemical Society.


Patsos, H. A., Hicks, D. J., Greenhough, A., Williams, A. C., & Paraskeva, C. (2005). Cannabinoids and cancer: Potential for colorectal cancer therapy. Biochemical Society Transactions, 33(4), 712-714.

Journal Article Type Conference Paper
Acceptance Date Jul 31, 2005
Publication Date Aug 1, 2005
Journal Biochemical Society Transactions
Print ISSN 0300-5127
Publisher Portland Press
Peer Reviewed Peer Reviewed
Volume 33
Issue 4
Pages 712-714
Public URL
Publisher URL