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All Outputs (128)

Extraction-free, direct determination of caffeine in microliter volumes of beverages by thermal desorption-gas chromatography mass spectrometry (2020)
Journal Article
Peng, X., Brown, M., Bowdler, P., & Honeychurch, K. C. (2020). Extraction-free, direct determination of caffeine in microliter volumes of beverages by thermal desorption-gas chromatography mass spectrometry. International Journal of Analytical Chemistry, 2020, 1-7. https://doi.org/10.1155/2020/5405184

An extraction-free method requiring microliter (μL) volumes has been developed for the determination of caffeine in beverages. Using a pyrolysis-gas chromatography mass spectrometry system, the conditions required for the direct thermal desorption-g... Read More about Extraction-free, direct determination of caffeine in microliter volumes of beverages by thermal desorption-gas chromatography mass spectrometry.

The impact of the “World's 25 Most Endangered Primates” list on scientific publications and media (2020)
Journal Article
Acerbi, A., Kerhoas, D., Webber, A. D., McCabe, G., Mittermeier, R. A., & Schwitzer, C. (2020). The impact of the “World's 25 Most Endangered Primates” list on scientific publications and media. Journal for Nature Conservation, 54, 125794. https://doi.org/10.1016/j.jnc.2020.125794

Assessing the impact of conservation campaigns is of critical importance to optimise the use of limited resources. Lists of threatened species are often employed as media outreach tools, but their usefulness is rarely tested. We investigated whether... Read More about The impact of the “World's 25 Most Endangered Primates” list on scientific publications and media.

A Wnt-BMP4 signaling axis induces MSX and NOTCH proteins and promotes growth suppression and differentiation in neuroblastoma (2020)
Journal Article
Szemes, M., Melegh, Z., Bellamy, J., Greenhough, A., Kollareddy, M., Catchpoole, D., & Malik, K. (2020). A Wnt-BMP4 signaling axis induces MSX and NOTCH proteins and promotes growth suppression and differentiation in neuroblastoma. Cells, 9(3), Article 783. https://doi.org/10.3390/cells9030783

The Wnt and bone morphogenetic protein (BMP) signaling pathways are known to be crucial in the development of neural crest lineages, including the sympathetic nervous system. Surprisingly, their role in paediatric neuroblastoma, the prototypic tumor... Read More about A Wnt-BMP4 signaling axis induces MSX and NOTCH proteins and promotes growth suppression and differentiation in neuroblastoma.

Cyclic voltammetric behaviour of 2,4-dinitrotoluene at a glassy carbon electrode (2020)
Journal Article
Honeychurch, K. (2020). Cyclic voltammetric behaviour of 2,4-dinitrotoluene at a glassy carbon electrode. Scholarly Community Encyclopedia, 2019,

This paper describes the development of a simple voltammetric method for the measurement of 2,4-dinitrotoluene (24DNT) at glassy carbon electrode (GCE). Initial investigations were undertaken using cyclic voltammetry to characterise the redox behavio... Read More about Cyclic voltammetric behaviour of 2,4-dinitrotoluene at a glassy carbon electrode.

BCL–3 promotes cyclooxygenase–2/prostaglandin E2 signalling in colorectal cancer (2020)
Journal Article
Collard, T. J., Fallatah, H. M., Greenhough, A., Paraskeva, C., & Williams, A. C. (2020). BCL–3 promotes cyclooxygenase–2/prostaglandin E2 signalling in colorectal cancer. International Journal of Oncology, 56(5), 1304-1313. https://doi.org/10.3892/ijo.2020.5013

First discovered as an oncogene in leukaemia, recent reports highlight an emerging role for the proto-oncogene BCL-3 in solid tumours. Importantly, BCL-3 expression is upregulated in >30% of colorectal cancer cases and is reported to be associated wi... Read More about BCL–3 promotes cyclooxygenase–2/prostaglandin E2 signalling in colorectal cancer.

Taxonomy of prokaryotic viruses: 2018-2019 update from the ICTV Bacterial and Archaeal Viruses Subcommittee (2020)
Journal Article
Adriaenssens, E. M., Sullivan, M. B., Knezevic, P., van Zyl, L. J., Sarkar, B. L., Dutilh, B. E., …Krupovic, M. (2020). Taxonomy of prokaryotic viruses: 2018-2019 update from the ICTV Bacterial and Archaeal Viruses Subcommittee. Archives of Virology, 165(5), 1253-1260. https://doi.org/10.1007/s00705-020-04577-8

This article is a summary of the activities of the ICTV’s Bacterial and Archaeal Viruses Subcommittee for the years 2018 and 2019. Highlights include the creation of a new order, 10 families, 22 subfamilies, 424 genera and 964 species. Some of our co... Read More about Taxonomy of prokaryotic viruses: 2018-2019 update from the ICTV Bacterial and Archaeal Viruses Subcommittee.

Development of a facile fluorophosphonate-functionalised titanium surface for potential orthopaedic applications (2020)
Journal Article
Shiel, A. I., Ayre, W. N., Blom, A. W., Hallam, K. R., Heard, P. J., Payton, O., …Mansell, J. P. (2020). Development of a facile fluorophosphonate-functionalised titanium surface for potential orthopaedic applications. Journal of Orthopaedic Translation, 23, 140-151. https://doi.org/10.1016/j.jot.2020.02.002

Background: Aseptic loosening of total joint replacements (TJRs) continues to be the main cause of implant failures. The socioeconomic impact of surgical revisions is hugely significant; in the United Kingdom alone, it is estimated that £137 m is spe... Read More about Development of a facile fluorophosphonate-functionalised titanium surface for potential orthopaedic applications.

Contrasting sensitivity of nestling and fledgling Barn Swallow Hirundo rustica body mass to local weather conditions (2020)
Journal Article
Facey, R. J., Vafidis, J. O., Smith, J. A., Vaughan, I. P., & Thomas, R. J. (2020). Contrasting sensitivity of nestling and fledgling Barn Swallow Hirundo rustica body mass to local weather conditions. Ibis, 62(4), 1163-1174. https://doi.org/10.1111/ibi.12824

Local weather can influence the growth and development of young birds either indirectly, by modifying prey availability, or directly, by affecting energetic trade-offs. Such effects can have lasting implications for life history traits, but the natur... Read More about Contrasting sensitivity of nestling and fledgling Barn Swallow Hirundo rustica body mass to local weather conditions.

Improving representation of female researchers in peer review and publishing (2020)
Presentation / Conference
Fogg Rogers, L. (2020, February). Improving representation of female researchers in peer review and publishing. Presented at Research to Reader, London, UK

There is a significant under-representation of women in STEM research which is damaging societal progress for democratic, utilitarian and equity reasons. Academic grants and publishing are a key part of the problem as peer review is conducted for fre... Read More about Improving representation of female researchers in peer review and publishing.

Pseudomonas kirkiae sp. nov., a novel species isolated from oak in the United Kingdom, and phylogenetic considerations of the genera Pseudomonas, Azotobacter and Azomonas (2020)
Journal Article
Bueno-Gonzalez, V., Brady, C., Denman, S., Allainguillaume, J., & Arnold, D. (2020). Pseudomonas kirkiae sp. nov., a novel species isolated from oak in the United Kingdom, and phylogenetic considerations of the genera Pseudomonas, Azotobacter and Azomonas. International Journal of Systematic and Evolutionary Microbiology, 70(4), 2426-2434. https://doi.org/10.1099/ijsem.0.004055

As the current episode of Acute Oak Decline (AOD) continues to affect native British oak in the United Kingdom, ongoing isola-tions from symptomatic and healthy oak have yielded a large Pseudomonas species population. These strains could be divided i... Read More about Pseudomonas kirkiae sp. nov., a novel species isolated from oak in the United Kingdom, and phylogenetic considerations of the genera Pseudomonas, Azotobacter and Azomonas.

Visualizing the invisible: Performing chaos theory (2020)
Journal Article
Weitkamp, E. (2021). Visualizing the invisible: Performing chaos theory. Leonardo, 54(3), 289-293. https://doi.org/10.1162/leon_a_01887

Edward Lorenz, a pioneering figure in the field of chaos theory, coined the phrase “butterfly effect” and posed the well-known question “Does the flap of a butterfly’s wings in Brazil set off a tornado in Texas?” In posing the question, Lorenz sought... Read More about Visualizing the invisible: Performing chaos theory.

In vitro modelling of tongue derived microbial biofilms and their reponse to treatment (2020)
Thesis
Hewett, K. E. In vitro modelling of tongue derived microbial biofilms and their reponse to treatment. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/1491292

This work concerns the development of a flat plate perfusion model to study biofilms derived from human tongue biota. The model has been derived from a previous sorbarod model, via a flat plate model (used to study wound organisms), to the model desc... Read More about In vitro modelling of tongue derived microbial biofilms and their reponse to treatment.

Targeting the splice factor kinase CLK1 in prostate cancer cells (2020)
Thesis
Uzor, S. O. Targeting the splice factor kinase CLK1 in prostate cancer cells. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/1490733

Prostate cancer is the most rampant diagnosed cancer and the second leading cause of cancer related death in men between middle age and old age. There is a need to identify the molecular genetic processes that underpin prostate cancer and to search f... Read More about Targeting the splice factor kinase CLK1 in prostate cancer cells.

Antimicrobial activity of essential oils as liquid and vapour applications (2020)
Thesis
Elcocks, E. R. (2020). Antimicrobial activity of essential oils as liquid and vapour applications. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/1490727

Essential oils produced by plants have been used as antimicrobial agents historically, however, many essential oils remain under-exploited as alternatives to antimicrobials. Therefore, the aim of this thesis was to evaluate the antibacterial efficacy... Read More about Antimicrobial activity of essential oils as liquid and vapour applications.

Understanding Conflicts About Wildlife: A Biosocial Approach (2020)
Book
Hill, C., Webber, A., & Priston, N. (Eds.). (2020). Understanding Conflicts About Wildlife: A Biosocial Approach. Berghahn. https://doi.org/10.2307/j.ctvw04h12

Conflicts about wildlife are usually portrayed and understood as resulting from the negative impacts of wildlife on human livelihoods or property. However, a greater depth of analysis reveals that many instances of human-wildlife conflict are often b... Read More about Understanding Conflicts About Wildlife: A Biosocial Approach.

BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease (2020)
Journal Article
Harris, M., El Hindy, M., Usmari-Moraes, M., Hudd, F., Shafei, M., Dong, M., …Conway, M. E. (in press). BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease. Free Radical Biology and Medicine, https://doi.org/10.1016/j.freeradbiomed.2020.01.019

Leucine, nutrient signal and substrate for the branched chain aminotransferase (BCAT) activates the mechanistic target of rapamycin (mTORC1) and regulates autophagic flux, mechanisms implicated in the pathogenesis of neurodegenerative conditions such... Read More about BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease.