Skip to main content

Research Repository

Advanced Search

All Outputs (92)

An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome (2013)
Journal Article
Probert, C. S., de Costello, B. L., Ahmed, I., Greenwood, R., de Lacy Costello, B., Ratcliffe, N. M., & Probert, C. (2013). An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome. PLoS ONE, 8(3), https://doi.org/10.1371/journal.pone.0058204

Diagnosing irritable bowel syndrome (IBS) can be a challenge; many clinicians resort to invasive investigations in order to rule out other diseases and reassure their patients. Volatile organic metabolites (VOMs) are emitted from feces; understanding... Read More about An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome.

Volatiles from oral anaerobes confounding breath biomarker discovery (2013)
Journal Article
De Lacy Costello, B., Khalid, T. Y., Ratcliffe, N. M., Khalid, T., Saad, S., Greenman, J., …Ratcliffe, N. M. (2013). Volatiles from oral anaerobes confounding breath biomarker discovery. Journal of Breath Research, 7(1), https://doi.org/10.1088/1752-7155/7/1/017114

The levels of compounds in exhaled mouth air do not necessarily reflect levels in the systemic circulation as bacteria can bio-transform substrates to produce compounds within the mouth. This should be of concern to researchers measuring breath volat... Read More about Volatiles from oral anaerobes confounding breath biomarker discovery.

Hepatic lipogenic enzyme expression in pigs is affected by selection for decreased backfat thickness at constant intramuscular fat content (2013)
Journal Article
Doran, O., Muñoz, R., Munoz, R., Estany, J., Tor, M., & Doran, O. (2013). Hepatic lipogenic enzyme expression in pigs is affected by selection for decreased backfat thickness at constant intramuscular fat content. Meat Science, 93(3), 746-751. https://doi.org/10.1016/j.meatsci.2012.11.045

This study investigated (i) whether genetic selection for decreased backfat thickness at constant intramuscular fat (IMF) affects the expression of lipogenic enzymes in pig liver and (ii) whether expression of the hepatic lipogenic enzymes is related... Read More about Hepatic lipogenic enzyme expression in pigs is affected by selection for decreased backfat thickness at constant intramuscular fat content.

Novel immunoassay technique for rapid measurement of intracellular proteins using paramagnetic particles (2013)
Journal Article
Sharif, E., Kiely, J., & Luxton, R. (2013). Novel immunoassay technique for rapid measurement of intracellular proteins using paramagnetic particles. Journal of Immunological Methods, 388(1-2), 78-85. https://doi.org/10.1016/j.jim.2012.11.015

Magnetic immunoassays have been shown to have similar detection limits to conventional immunoassays, with the advantage of reduced total assay time. The aim of this study was to demonstrate that an integrated lysis and measurement system could be use... Read More about Novel immunoassay technique for rapid measurement of intracellular proteins using paramagnetic particles.

Development of an amperometric screen-printed galactose biosensor for serum analysis (2013)
Journal Article
Pemberton, R. M., Kanyong, P., Pemberton, R., Jackson, S. K., & Hart, J. P. (2013). Development of an amperometric screen-printed galactose biosensor for serum analysis. Analytical Biochemistry, 435(2), 114-119. https://doi.org/10.1016/j.ab.2013.01.006

The development of a disposable amperometric biosensor for the measurement of circulating galactose in serum is described. The biosensor comprises a screen-printed carbon electrode (SPCE), incorporating the electrocatalyst cobalt phthalocyanine (CoPC... Read More about Development of an amperometric screen-printed galactose biosensor for serum analysis.

Practical investigation of the factors that affect the selectivity in hydrophilic interaction chromatography (2013)
Journal Article
Kumar, A., Heaton, J. C., & McCalley, D. V. (2013). Practical investigation of the factors that affect the selectivity in hydrophilic interaction chromatography. Journal of Chromatography A, 1276, 33-46. https://doi.org/10.1016/j.chroma.2012.12.037

Retention data for a series of 29 compounds comprising acids, bases and neutrals were obtained on six different hydrophilic interaction (HILIC) columns including bare silica, zwitterionic and those bonded with neutral bonded ligands. The principal ai... Read More about Practical investigation of the factors that affect the selectivity in hydrophilic interaction chromatography.

The influence of a fluid-porous interface on solar pond stability (2013)
Journal Article
Hill, A. A., Hill, A. A., & Carr, M. (2013). The influence of a fluid-porous interface on solar pond stability. Advances in Water Resources, 52, 1-6. https://doi.org/10.1016/j.advwatres.2012.08.009

The linear instability of the gradient zone of a solar pond containing a fluid-porous interface is investigated. It is found that the gradient zone can retain the same stability for lower values of the solute Rayleigh number with the introduction of... Read More about The influence of a fluid-porous interface on solar pond stability.

The modelling of blood coagulation using the quartz crystal microbalance (2013)
Journal Article
Killard, A. J., Efremov, V., Killard, A., Byrne, B., & Lakshmanan, R. S. (2013). The modelling of blood coagulation using the quartz crystal microbalance. Journal of Biomechanics, 46(3), 437-442. https://doi.org/10.1016/j.jbiomech.2012.10.001

Blood is a clinically-important analytical matrix that is routinely selected for disease monitoring. Having a clear understanding of the mechanisms involved in blood coagulation is a key consideration in haemostasis, with modern clinical practices re... Read More about The modelling of blood coagulation using the quartz crystal microbalance.

Intraguild predation in winter wheat: Prey choice by a common epigeal carabid consuming spiders (2013)
Journal Article
Symondson, W. O., Davey, J. S., Vaughan, I. P., Andrew King, R., Bell, J. R., Bohan, D. A., …Holland, J. M. (2013). Intraguild predation in winter wheat: Prey choice by a common epigeal carabid consuming spiders. Journal of Applied Ecology, 50(1), 271-279. https://doi.org/10.1111/1365-2664.12008

Predators can provide a valuable ecosystem service by suppressing crop pests. However, intraguild predation, where predators compete for the same prey resource whilst consuming each other, may destabilize population dynamics and increase the risk of... Read More about Intraguild predation in winter wheat: Prey choice by a common epigeal carabid consuming spiders.

The first self-sustainable microbial fuel cell stack (2013)
Journal Article
Ledezma, P., Stinchcombe, A., Greenman, J., & Ieropoulos, I. (2013). The first self-sustainable microbial fuel cell stack. Physical Chemistry Chemical Physics, 15(7), 2278-2281. https://doi.org/10.1039/c2cp44548d

This study reports for the first time on the development of a self-sustainable microbial fuel cell stack capable of self-maintenance (feeding, hydration, sensing & reporting). Furthermore, the stack system is producing excess energy, which can be use... Read More about The first self-sustainable microbial fuel cell stack.

A sensor probe for the continuous in situ monitoring of ammonia leakage in secondary refrigerant systems (2013)
Journal Article
Killard, A. J., Subramanian, R., Crowley, K., Morrin, A., & Killard, A. (2013). A sensor probe for the continuous in situ monitoring of ammonia leakage in secondary refrigerant systems. Analytical Methods, 5(1), 134-140. https://doi.org/10.1039/c2ay25688f

Ammonia is becoming more widely used in refrigeration systems due to the phasing out of CFCs and HCFCs. However, ammonia is a toxic gas and its leakage from refrigeration systems can lead to human exposure and contamination of refrigerated food stuff... Read More about A sensor probe for the continuous in situ monitoring of ammonia leakage in secondary refrigerant systems.

Influence of dna repair on nonlinear dose-responses for mutation (2013)
Journal Article
Johnson, G. E., Doak, S. H., Lewis, P. D., Bodger, O. G., Thomas, A. D., Jenkins, G. J., …Johnson, G. (2013). Influence of dna repair on nonlinear dose-responses for mutation. Toxicological Sciences, 132(1), 87-95. https://doi.org/10.1093/toxsci/kfs341

Recent evidence has challenged the default assumption that all DNA-reactive alkylating agents exhibit a linear dose-response. Emerging evidence suggests that the model alkylating agents methyl- and ethylmethanesulfonate and methylnitrosourea (MNU) an... Read More about Influence of dna repair on nonlinear dose-responses for mutation.

Mitigating the Effect of Development on Bats in England with Derogation Licensing (2013)
Journal Article
Stone, E. L., Stone, E., Jones, G., & Harris, S. (2013). Mitigating the Effect of Development on Bats in England with Derogation Licensing. Conservation Biology, 27(6), 1324-1334. https://doi.org/10.1111/cobi.12154

The Convention on Biological Diversity has catalyzed worldwide awareness of threats to biological diversity and stimulated global conservation strategies. These have led to national and international legislation and have generated debate about the mo... Read More about Mitigating the Effect of Development on Bats in England with Derogation Licensing.

Bioprospecting the thermal waters of the Roman baths: Isolation of oleaginous species and analysis of the FAME profile for biodiesel production (2013)
Journal Article
Smith-Bädorf, H. D., Chuck, C. J., Mokebo, K. R., MacDonald, H., Davidson, M. G., & Scott, R. J. (2013). Bioprospecting the thermal waters of the Roman baths: Isolation of oleaginous species and analysis of the FAME profile for biodiesel production. AMB Express, 3(1), 1-14. https://doi.org/10.1186/2191-0855-3-9

The extensive diversity of microalgae provides an opportunity to undertake bioprospecting for species possessing features suited to commercial scale cultivation. The outdoor cultivation of microalgae is subject to extreme temperature fluctuations; te... Read More about Bioprospecting the thermal waters of the Roman baths: Isolation of oleaginous species and analysis of the FAME profile for biodiesel production.

Coagulation monitoring devices: Past, present, and future at the point of care (2013)
Journal Article
Killard, A. J., Harris, L. F., Harris, L. F., Castro-López, V., & Killard, A. (2013). Coagulation monitoring devices: Past, present, and future at the point of care. Trends in Analytical Chemistry, 50, 85-95. https://doi.org/10.1016/j.trac.2013.05.009

Automated technologies have revolutionised the monitoring of coagulation disorders in the central hospital laboratory setting, allowing for high throughput testing, improved accuracy and precision, accompanied by a marked reduction in human error. Ho... Read More about Coagulation monitoring devices: Past, present, and future at the point of care.

Conjugated linoleate reduces prostate cancer viability whereas the effects of oleate and stearate are cell line-dependent (2013)
Journal Article
Hagen, R., Rhodes, A., & Ladomery, M. (2013). Conjugated linoleate reduces prostate cancer viability whereas the effects of oleate and stearate are cell line-dependent. Anticancer Research, 33(10), 4395-4400

BACKGROUND: In this study, responses to fatty acid treatments in commonly used prostate cancer cell culture models and variability of gene expression between them were determined. MATERIALS AND METHODS: PC3, DU145, LNCaP, VCaP and PNT2 cells... Read More about Conjugated linoleate reduces prostate cancer viability whereas the effects of oleate and stearate are cell line-dependent.