Skip to main content

Research Repository

Advanced Search

Hepatic lipogenic enzyme expression in pigs is affected by selection for decreased backfat thickness at constant intramuscular fat content

Mu�oz, R.; Doran, O.; Munoz, R.; Estany, J.; Doran, Olena; Tor, M.

Authors

R. Mu�oz

O. Doran

R. Munoz

J. Estany

Olena Doran Olena.Doran@uwe.ac.uk
College Dean of Research and Enterprise

M. Tor



Abstract

This study investigated (i) whether genetic selection for decreased backfat thickness at constant intramuscular fat (IMF) affects the expression of lipogenic enzymes in pig liver and (ii) whether expression of the hepatic lipogenic enzymes is related to subcutaneous fat and IMF fatty acid composition. The enzymes investigated were fatty acid synthase (FAS), stearoyl-CoA desaturase and δ6-desaturase (δ6d). Experiments were conducted on 30 barrows (15 controls and 15 selected). Selected pigs had lower backfat thickness, which was accompanied by a reduced expression of the hepatic FAS and δ6d when compared to control pigs. There was a trend towards a positive relationship between FAS and δ6d protein expression and saturated and polyunsaturated fatty acids content respectively, in subcutaneous fat but not in muscle. It was concluded that selection against backfat thickness is associated with changes in expression of the hepatic FAS and δ6d proteins. The changes in protein expression did not influence significantly the tissue fatty acid composition under these conditions. © 2012 Elsevier Ltd.

Citation

Doran, O., Muñoz, R., Munoz, R., Estany, J., Tor, M., & Doran, O. (2013). Hepatic lipogenic enzyme expression in pigs is affected by selection for decreased backfat thickness at constant intramuscular fat content. Meat Science, 93(3), 746-751. https://doi.org/10.1016/j.meatsci.2012.11.045

Journal Article Type Article
Publication Date Mar 1, 2013
Journal Meat Science
Print ISSN 0309-1740
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 93
Issue 3
Pages 746-751
DOI https://doi.org/10.1016/j.meatsci.2012.11.045
Keywords fatty acid composition, intramuscular fat, lipogenic enzymes, pig, subcutaneous fat
Public URL https://uwe-repository.worktribe.com/output/934454
Publisher URL http://dx.doi.org/10.1016/j.meatsci.2012.11.045