Skip to main content

Research Repository

Advanced Search

All Outputs (88)

The histidine kinase AHK5 integrates endogenous and environmental signals in Arabidopsis guard cells (2008)
Journal Article
Desikan, R., Horák, J., Chaban, C., Mira-Rodado, V., Witthöft, J., Elgass, K., …Harter, K. (2008). The histidine kinase AHK5 integrates endogenous and environmental signals in Arabidopsis guard cells. PLoS ONE, 3(6), 1-15. https://doi.org/10.1371/journal.pone.0002491

Background: Stomatal guard cells monitor and respond to environmental and endogenous signals such that the stomatal aperture is continually optimised for water use efficiency. A key signalling molecule produced in guard cells in response to plant hor... Read More about The histidine kinase AHK5 integrates endogenous and environmental signals in Arabidopsis guard cells.

Antioxidative responses in radish (Raphanus sativus L.) plants stressed by copper and lead in nutrient solution and soil (2008)
Journal Article
Teklic, T., Hancock, J. T., Engler, M., Paradikovic, N., Cesar, V., Lepeduš, H., …Bešlo, D. (2008). Antioxidative responses in radish (Raphanus sativus L.) plants stressed by copper and lead in nutrient solution and soil. Acta Biologica Cracoviensia Series Botanica, 50(2), 79-86

Radish (Raphanus sativus L.) is commonly grown in urban and suburban areas where the soil may be polluted with heavy metals such as Cu or Pb. In this study, short exposure of radish plantlets to 0.5 mM Cu or Pb in nutrient solution (two days) in grow... Read More about Antioxidative responses in radish (Raphanus sativus L.) plants stressed by copper and lead in nutrient solution and soil.

Tools to investigate ROS sensitive signalling proteins (2008)
Journal Article
Desikan, R., Neill, S., Slinn, J., & Hancock, J. T. (2008). Tools to investigate ROS sensitive signalling proteins. Methods in Molecular Biology, 476, 87-99. https://doi.org/10.1007/978-1-59745-129-1_7

The thiols groups of cysteine residues on proteins are attractive oxidative targets for modification by reactive oxygen species, such as hydrogen peroxide (H2O2). Such modification can lead to important cellular signaling processes that ultimately re... Read More about Tools to investigate ROS sensitive signalling proteins.

Nitric oxide, stomatal closure, and abiotic stress (2008)
Journal Article
Ribeiro, D., Harrison, J., Neill, S., Barros, R. S., Bright, J., Desikan, R., …Wilson, I. D. (2008). Nitric oxide, stomatal closure, and abiotic stress. Journal of Experimental Botany, 59(2), 165-176. https://doi.org/10.1093/jxb/erm293

Various data indicate that nitric oxide (NO) is an endogenous signal in plants that mediates responses to several stimuli. Experimental evidence in support of such signalling roles for NO has been obtained via the application of NO, usually in the fo... Read More about Nitric oxide, stomatal closure, and abiotic stress.

Nitric oxide signalling in plants (2008)
Journal Article
Wilson, I. D., Neill, S., & Hancock, J. T. (2008). Nitric oxide signalling in plants. Plant, Cell and Environment, 31(5), 622-631. https://doi.org/10.1111/j.1365-3040.2007.01761.x

As with all organisms, plants must respond to a plethora of external environmental cues. Individual plant cells must also perceive and respond to a wide range of internal signals. It is now well-accepted that nitric oxide (NO) is a component of the r... Read More about Nitric oxide signalling in plants.

Implications of dealing with airborne substances and reactive oxygen species: What mammalian lungs, animals, and plants have to say (2007)
Journal Article
Filho, D. W., Hermes-Lima, M., Oliveira, E. S., Spinelli de Oliveira, E., Hancock, J. T., Isola, D. A., …Wilhelm Filho, D. (2007). Implications of dealing with airborne substances and reactive oxygen species: What mammalian lungs, animals, and plants have to say. Integrative and Comparative Biology, 47(4), 578-591. https://doi.org/10.1093/icb/icm078

A gas-exchange structure interacts with the environment and is constantly challenged by contaminants that may elicit defense responses, thus compromising its primary function. It is also exposed to high concentrations of O2 that can generate reactive... Read More about Implications of dealing with airborne substances and reactive oxygen species: What mammalian lungs, animals, and plants have to say.

Nitric oxide, stomatal closure and abiotic stress (2007)
Journal Article
Neill, S., Barros, R. S., Bright, J., Desikan, R., Hancock, J. T., Harrison, J., …Ribeiro, D. M. (2007). Nitric oxide, stomatal closure and abiotic stress. Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, 146(4), S257. https://doi.org/10.1016/j.cbpa.2007.01.648

Various data indicate that nitric oxide (NO) is an endogenous signal in plants that mediates responses to several stimuli. Experimental evidence in support of such signalling roles for NO has been obtained via the application of NO (usually in the fo... Read More about Nitric oxide, stomatal closure and abiotic stress.

Signaling on the stigma: Potential new roles for ROS and NO in plant cell signaling (2007)
Journal Article
Hiscock, S. J., Bright, J., McInnis, S. M., Desikan, R., & Hancock, J. T. (2007). Signaling on the stigma: Potential new roles for ROS and NO in plant cell signaling. Plant Signaling and Behavior, 2(1), 23-24

Reactive oxygen species (ROS) and reactive nitrogen species, particularly NO, are key components of diverse signaling networks in animals and plants. We have recently shown that epidermal cells of stigmas from a range of different angiosperms accumul... Read More about Signaling on the stigma: Potential new roles for ROS and NO in plant cell signaling.

Production of reactive oxygen species and reactive nitrogen species by angiosperm stigmas and pollen: Potential signalling crosstalk? (2006)
Journal Article
McInnis, S. M., Desikan, R., Hancock, J. T., & Hiscock, S. J. (2006). Production of reactive oxygen species and reactive nitrogen species by angiosperm stigmas and pollen: Potential signalling crosstalk?. New Phytologist, 172(2), 221-228. https://doi.org/10.1111/j.1469-8137.2006.01875.x

• Angiosperm stigmas exhibit high levels of peroxidase activity when receptive to pollen. To explore possible function(s) of this peroxidase activity we investigated amounts of reactive oxygen species (ROS), particularly hydrogen peroxide, in stigmas... Read More about Production of reactive oxygen species and reactive nitrogen species by angiosperm stigmas and pollen: Potential signalling crosstalk?.

Ethylene-induced stomatal closure in Arabidopsis occurs via AtrbohF-mediated hydrogen peroxide synthesis (2006)
Journal Article
Desikan, R., Last, K., Harrett-Williams, R., Tagliavia, C., Harter, K., Hooley, R., …Neill, S. (2006). Ethylene-induced stomatal closure in Arabidopsis occurs via AtrbohF-mediated hydrogen peroxide synthesis. Plant Journal, 47(6), 907-916. https://doi.org/10.1111/j.1365-313X.2006.02842.x

Ethylene is a plant hormone that regulates many aspects of growth and development. Despite the well-known association between ethylene and stress signalling, its effects on stomatal movements are largely unexplored. Here, genetic and physiological da... Read More about Ethylene-induced stomatal closure in Arabidopsis occurs via AtrbohF-mediated hydrogen peroxide synthesis.

ABA-induced NO generation and stomatal closure in Arabidopsis are dependent on H2O2 synthesis (2006)
Journal Article
Bright, J., Desikan, R., Hancock, J. T., Weir, I. S., & Neill, S. (2006). ABA-induced NO generation and stomatal closure in Arabidopsis are dependent on H2O2 synthesis. Plant Journal, 45(1), 113-122. https://doi.org/10.1111/j.1365-313X.2005.02615.x

Nitric oxide (NO) and hydrogen peroxide (H2O2) are key signalling molecules produced in response to various stimuli and involved in a diverse range of plant signal transduction processes. Nitric oxide and H 2O2 have been identified as essential compo... Read More about ABA-induced NO generation and stomatal closure in Arabidopsis are dependent on H2O2 synthesis.

Proteomic identification of glyceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis (2005)
Journal Article
Harrison, J., Hancock, J. T., Henson, D., Nyirenda, M., Desikan, R., Lewis, M., …Neill, S. (2005). Proteomic identification of glyceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis. Plant Physiology and Biochemistry, 43(9), 828-835. https://doi.org/10.1016/j.plaphy.2005.07.012

Hydrogen peroxide (H2O2) is now recognised as a key signalling molecule in eukaryotes. In plants, H2O2 is involved in regulating stomatal closure, gravitropic responses, gene expression and programmed cell death. Although several kinases, such as oxi... Read More about Proteomic identification of glyceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis.

Recording forces exerted on the bowel wall during colonoscopy: in vitro evaluation. (2005)
Journal Article
Dogramadzi, S., Virk, G. S., Bell, G. D., Rowland, R. S., & Hancock, J. (2005). Recording forces exerted on the bowel wall during colonoscopy: in vitro evaluation. International Journal of Medical Robotics and Computer Assisted Surgery, 1(4), 89-97. https://doi.org/10.1002/rcs.61

A novel system for distributed force measurement between the bowel wall and the shaft of a colonoscope is presented. The system, based on the piezoresistive method, involves the integration of soft miniature transducers to a colonoscope to enable a w... Read More about Recording forces exerted on the bowel wall during colonoscopy: in vitro evaluation..

DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines (2004)
Journal Article
Gray, A. G., Morgan, L. M., Avent, N. D., Smith, M. A., Court, E. L., Hancock, J. T., & Smith, J. G. (2004). DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines. Leukemia Research, 28(7), 743-753. https://doi.org/10.1016/j.leukres.2003.11.011

This study used cDNA microarray technology to compare gene expression profiles in acute myeloblastic leukaemia (AML) with cDNA dot-blot and real time PCR analysis of cDNA transcripts to confirm array data. Patient AML marrow samples and AML cell line... Read More about DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines.

New equations for redox and nano-signal transduction (2004)
Journal Article
Hancock, J. T., Desikan, R., Neill, S., & Cross, A. R. (2004). New equations for redox and nano-signal transduction. Journal of Theoretical Biology, 226(1), 65-68. https://doi.org/10.1016/j.jtbi.2003.08.003

Cells maintain redox potentials (Eh) in intracellular compartments, sometimes referred to as redox environments. These potentials are often very reducing, for example in the cytoplasm, but throughout the cell different potentials are maintained, comm... Read More about New equations for redox and nano-signal transduction.

Hydrogen peroxide is a common signal for darkness and ABA-induced stomatal closure in Pisum sativum L. (2004)
Journal Article
Desikan, R., Cheung, M., Clarke, A., Golding, S., Sagi, M., Fluhr, R., …Neill, S. (2004). Hydrogen peroxide is a common signal for darkness and ABA-induced stomatal closure in Pisum sativum L. Functional Plant Biology, 31(9), 913-920

The requirement for hydrogen peroxide (H2O2) generation and action during stomatal closure induced by darkness and abscisic acid (ABA) was investigated in pea (Pisum sativum L.). Stomatal closure induced by darkness or ABA was inhibited by the H2O2-s... Read More about Hydrogen peroxide is a common signal for darkness and ABA-induced stomatal closure in Pisum sativum L..