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Towards slime mould chemical sensor: Mapping chemical inputs onto electrical potential dynamics of Physarum Polycephalum (2013)
Journal Article
De Lacy Costello, B. P., Whiting, J. G., Whiting, J., de Lacy Costello, B., & Adamatzky, A. (2014). Towards slime mould chemical sensor: Mapping chemical inputs onto electrical potential dynamics of Physarum Polycephalum. Sensors and Actuators B: Chemical, 191, 844-853. https://doi.org/10.1016/j.snb.2013.10.064

Plasmodium of slime mould Physarum polycephalum is a large single celled organism visible unaided by the eye. This slime mould is capable of optimising the shape of its protoplasmic networks in spatial configurations of attractants and repellents. Su... Read More about Towards slime mould chemical sensor: Mapping chemical inputs onto electrical potential dynamics of Physarum Polycephalum.

Breath volatile analysis from patients diagnosed with harmful drinking, cirrhosis and hepatic encephalopathy: A pilot study (2013)
Journal Article
Ratcliffe, N. M., Costello, B. D. L., Khalid, T. Y., de Lacy Costello, B., Ewen, R., White, P., …Probert, C. S. (2013). Breath volatile analysis from patients diagnosed with harmful drinking, cirrhosis and hepatic encephalopathy: A pilot study. Metabolomics, 9(5), 938-948. https://doi.org/10.1007/s11306-013-0510-4

Hepatic encephalopathy (HE) is a neuropsychiatric state potentially complicating cirrhosis following the accumulation of toxic compounds that cross the blood-brain barrier and affect brain function; the compounds may undergo alveolar gas exchange and... Read More about Breath volatile analysis from patients diagnosed with harmful drinking, cirrhosis and hepatic encephalopathy: A pilot study.

An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS (2013)
Journal Article
Ratcliffe, N., De Lacy Costello, B., Al-Kateb, H., de Lacy Costello, B., & Ratcliffe, N. M. (2013). An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS. Journal of Breath Research, 7(3), https://doi.org/10.1088/1752-7155/7/3/036004

Analysis of volatile organic compounds (VOCs) from saliva, to aid disease diagnoses, has received little attention. This work aims to address the paucity of information on saliva volatiles and includes a database of newly identified compounds whilst... Read More about An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS.

The Development of Novel Fuel Dehydrating Icing Inhibitors (2013)
Journal Article
Lam, J. K., de Lacy Costello, B., Repetto, S. L., Repetto, S., Costello, J. F., de Lacy Costello, B., …Lam, J. (2013). The Development of Novel Fuel Dehydrating Icing Inhibitors. SAE International Journal of Fuels and Lubricants, 6(3), 553-563. https://doi.org/10.4271/2013-01-2169

Dissolved water is a normal component of jet fuel which is vapourised during combustion; however, free water is a contaminant that can starve engines, freeze to form ice crystals capable of blocking fuel feeds, support microbial growth, and contribut... Read More about The Development of Novel Fuel Dehydrating Icing Inhibitors.

Analysis of the volatiles in the headspace above the plasmodium and sporangia of the slime mould (Physarum polycephalum) by SPME-GCMS (2013)
Journal Article
AL-Kateb, H., & Costello, B. D. L. (2013). Analysis of the volatiles in the headspace above the plasmodium and sporangia of the slime mould (Physarum polycephalum) by SPME-GCMS

Solid phase micro-extraction (SPME) coupled with Gas Chromatography Mass Spectrometry (GC-MS) was used to extract and analyse the volatiles in the headspace above the plasmodial and sporulating stages of the slime mould Physarum Polycephalum. In tota... Read More about Analysis of the volatiles in the headspace above the plasmodium and sporangia of the slime mould (Physarum polycephalum) by SPME-GCMS.

A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace (2013)
Journal Article
Ratcliffe, N., Probert, C. S., Ewen, R., Khalid, T., White, P., De Lacy Costello, B., …Ratcliffe, N. M. (2013). A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace. PLoS ONE, 8(7), https://doi.org/10.1371/journal.pone.0069602

There is a need to reduce the number of cystoscopies on patients with haematuria. Presently there are no reliable biomarkers to screen for bladder cancer. In this paper, we evaluate a new simple in-house fabricated, GC-sensor device in the diagnosis... Read More about A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace.

Observation, characterization and modeling of memristor current spikes (2013)
Journal Article
Gale, E., de Lacy Costello, B., & Adamatzky, A. (2013). Observation, characterization and modeling of memristor current spikes. https://doi.org/10.12785/amis/070418

Memristors have been compared to neurons (usually specifically the synapses) since 1976 but no experimental evidence has been offered for support for this position. Here we highlight that memristors naturally form fast-response, highly reproducible a... Read More about Observation, characterization and modeling of memristor current spikes.

The importance of methane breath testing: A review (2013)
Journal Article
Ratcliffe, N. M., De Lacy Costello, B. P., de Lacy Costello, B., Ledochowski, M., & Ratcliffe, N. M. (2013). The importance of methane breath testing: A review. Journal of Breath Research, 7(2), https://doi.org/10.1088/1752-7155/7/2/024001

Sugar malabsorption in the bowel can lead to bloating, cramps, diarrhea and other symptoms of irritable bowel syndrome as well as affecting absorption of other nutrients. The hydrogen breath test is now a well established noninvasive test for assessi... Read More about The importance of methane breath testing: A review.

The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease (2013)
Journal Article
Ratcliffe, N. M., de Lacy Costello, B., & Shepherd, S. (2013). The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease. Clinical laboratory international, 37, 18-20

Currently, the diagnosis of bowel diseases such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) relies on invasive and expensive procedures. Identification of biomarker-based tests to aid diagnosis is an important area of resea... Read More about The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease.

Design of a hybrid robot control system using memristor-model and ant-inspired based information transfer protocols (2013)
Presentation / Conference
Gale, E., de Lacy Costello, B., & Adamatzky, A. (2013, May). Design of a hybrid robot control system using memristor-model and ant-inspired based information transfer protocols. Paper presented at Workshop on Unconventional Approaches to Robotics, Automation and Control Inspired by Nature

It is not always possible for a robot to process all the information from its sensors in a timely manner and thus quick and yet valid approximations of the robot's situation are needed. Here we design hybrid control for a robot within this limit usin... Read More about Design of a hybrid robot control system using memristor-model and ant-inspired based information transfer protocols.

Does the D.C. response of memristors allow robotic short-term memory and a possible route to artificial time perception? (2013)
Presentation / Conference
Gale, E., de Lacy Costello, B., & Adamatzky, A. (2013, May). Does the D.C. response of memristors allow robotic short-term memory and a possible route to artificial time perception?. Paper presented at Workshop Unconventional Approaches to Robotics, Automation and Control Inspired by Nature (UARACIN) in:

Time perception is essential for task switching, and in the mammalian brain appears alongside other processes. Memristors are electronic components used as synapses and as models for neurons. The d.c. response of memristors can be considered as a typ... Read More about Does the D.C. response of memristors allow robotic short-term memory and a possible route to artificial time perception?.

Volatile organic compounds (VOCs) found in urine and stool (2013)
Book Chapter
de Lacy Costello, B., & Ratcliffe, N. M. (2013). Volatile organic compounds (VOCs) found in urine and stool. In A. Amann, & D. Smith (Eds.), Volatile Biomarkers: Non-Invasive Diagnosis in Physiology and Medicine, 405-462. Elsevier

Beyond Markov chains, towards adaptive memristor network-based music generation (2013)
Presentation / Conference
Gale, E., Matthews, O., de Lacy Costello, B., & Adamatzky, A. (2013, April). Beyond Markov chains, towards adaptive memristor network-based music generation. Paper presented at First AISB symposium on Music and Unconventional Computing

We undertook a study of the use of a memristor network for music generation, making use of the memristor's memory to go beyond the Markov hypothesis. Seed transition matrices are created and populated using memristor equations, and which are shown to... Read More about Beyond Markov chains, towards adaptive memristor network-based music generation.

An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome (2013)
Journal Article
Probert, C. S., de Costello, B. L., Ahmed, I., Greenwood, R., de Lacy Costello, B., Ratcliffe, N. M., & Probert, C. (2013). An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome. PLoS ONE, 8(3), https://doi.org/10.1371/journal.pone.0058204

Diagnosing irritable bowel syndrome (IBS) can be a challenge; many clinicians resort to invasive investigations in order to rule out other diseases and reassure their patients. Volatile organic metabolites (VOMs) are emitted from feces; understanding... Read More about An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome.

Volatiles from oral anaerobes confounding breath biomarker discovery (2013)
Journal Article
De Lacy Costello, B., Khalid, T. Y., Ratcliffe, N. M., Khalid, T., Saad, S., Greenman, J., …Ratcliffe, N. M. (2013). Volatiles from oral anaerobes confounding breath biomarker discovery. Journal of Breath Research, 7(1), https://doi.org/10.1088/1752-7155/7/1/017114

The levels of compounds in exhaled mouth air do not necessarily reflect levels in the systemic circulation as bacteria can bio-transform substrates to produce compounds within the mouth. This should be of concern to researchers measuring breath volat... Read More about Volatiles from oral anaerobes confounding breath biomarker discovery.

Toward turing’s A-type unorganised machines in an unconventional substrate: A dynamic representation in compartmentalised excitable chemical media (2013)
Book Chapter
Bull, L., Holley, J., De Lacy Costello, B., & Adamatzky, A. (2013). Toward turing’s A-type unorganised machines in an unconventional substrate: A dynamic representation in compartmentalised excitable chemical media. Springer. https://doi.org/10.1007/978-3-642-37225-4_11

© Springer-Verlag Berlin Heidelberg 2013. Turing presented a general representation scheme by which to achieve artificial intelligence – unorganised machines. Significantly, these were a form of discrete dynamical system and yet such representations... Read More about Toward turing’s A-type unorganised machines in an unconventional substrate: A dynamic representation in compartmentalised excitable chemical media.