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Sensors for determining volatile compounds based on electrical conductivity and cataluminescence measurements of metal oxide films (2019)
Patent
Cox, T., Kiely, J., Ratcliffe, N., deLacy Costello, B., & Luxton, R. (2019). Sensors for determining volatile compounds based on electrical conductivity and cataluminescence measurements of metal oxide films

The invention relates to the field of sensors for detecting volatile compounds. The sensor of the present invention for detecting volatile compounds comprises: a film of metal oxide; a heater configured to provide heat energy to the film of metal oxi... Read More about Sensors for determining volatile compounds based on electrical conductivity and cataluminescence measurements of metal oxide films.

Mapping outcomes of liquid marble collisions (2019)
Journal Article
Draper, T. C., Fullarton, C., Mayne, R., Phillips, N., Canciani, G. E., De Lacy Costello, B. P., & Adamatzky, A. (2019). Mapping outcomes of liquid marble collisions. Soft Matter, 15(17), 3541-3551. https://doi.org/10.1039/c9sm00328b

© 2019 The Royal Society of Chemistry. Liquid marbles (LMs) have many promising roles in the ongoing development of microfluidics, microreactors, bioreactors, and unconventional computing. In many of these applications, the coalescence of two LMs is... Read More about Mapping outcomes of liquid marble collisions.

Thermal switch of oscillation frequency in belousov- zhabotinsky liquid marbles (2019)
Journal Article
Adamatzky, A., Fullarton, C., Phillips, N., Costello, B. D. L., & Draper, T. C. (2019). Thermal switch of oscillation frequency in belousov- zhabotinsky liquid marbles. Royal Society Open Science, 6(4), 190078. https://doi.org/10.1098/rsos.190078

© 2019 The Authors. External control of oscillation dynamics in the Belousov- Zhabotinsky (BZ) reaction is important for many applications including encoding computing schemes. When considering the BZ reaction, there are limited studies dealing with... Read More about Thermal switch of oscillation frequency in belousov- zhabotinsky liquid marbles.

Sniffing out resistance – Rapid identification of urinary tract infection-causing bacteria and their antibiotic susceptibility using volatile metabolite profiles (2019)
Journal Article
Smart, A., de Lacy Costello, B., White, P., Avison, M., Batty, C., Turner, C., …Ratcliffe, N. (2019). Sniffing out resistance – Rapid identification of urinary tract infection-causing bacteria and their antibiotic susceptibility using volatile metabolite profiles. Journal of Pharmaceutical and Biomedical Analysis, 167, 59-65. https://doi.org/10.1016/j.jpba.2019.01.044

Antibiotic resistance is set to be an unprecedented threat to modern medicine. ‘Sniffing’ bacteria potentially offers a rapid way to determine susceptibility. A successful proof-of-principle study is described, using thermal desorption-gas chromatogr... Read More about Sniffing out resistance – Rapid identification of urinary tract infection-causing bacteria and their antibiotic susceptibility using volatile metabolite profiles.

Liquid Marble Actuator for Microfluidic Logic Systems (2018)
Journal Article
Draper, T. C., Fullarton, C., Phillips, N., de Lacy Costello, B. P. J., & Adamatzky, A. (2018). Liquid Marble Actuator for Microfluidic Logic Systems. Scientific Reports, 8(1), https://doi.org/10.1038/s41598-018-32540-w

© 2018, The Author(s). A mechanical flip-flop actuator has been developed that allows for the facile re-routing and distribution of liquid marbles (LMs) in digital microfluidic devices. Shaped loosely like a triangle, the actuating switch pivots fro... Read More about Liquid Marble Actuator for Microfluidic Logic Systems.

Gas chromatography mass spectrometry (GC-MS) quantification of metabolites in stool using13 C labelled compounds (2018)
Journal Article
Gould, O., Costello, B. D. L., Smart, A., Jones, P., Macmaster, A., Ransley, K., & Ratcliffe, N. (2018). Gas chromatography mass spectrometry (GC-MS) quantification of metabolites in stool using13 C labelled compounds. Metabolites, 8(4), 75. https://doi.org/10.3390/metabo8040075

© 2018 by the authors. Licensee MDPI, Basel, Switzerland. It has become increasingly important to qualitatively and quantitatively assess the volatile metabolites in a range of bodily fluids for use in monitoring health. There has been relatively lit... Read More about Gas chromatography mass spectrometry (GC-MS) quantification of metabolites in stool using13 C labelled compounds.

Belousov-Zhabotinsky reaction in liquid marbles (2018)
Journal Article
Fullarton, C., Draper, T., Phillips, N., de Lacy Costello, B., & Adamatzky, A. (2019). Belousov-Zhabotinsky reaction in liquid marbles. Journal of Physics: Materials, 2(1), https://doi.org/10.1088/2515-7639/aaed4c

In Belousov–Zhabotinsky (BZ) type reactions, chemical oxidation waves can be exploited to produce reaction-diffusion processors. This paper reports on a new method of encapsulating BZ solution in a powder coating of either polyethylene (PE) or polyte... Read More about Belousov-Zhabotinsky reaction in liquid marbles.

Evaporation, Lifetime, and Robustness Studies of Liquid Marbles for Collision-Based Computing (2018)
Journal Article
Fullarton, C., Draper, T., Phillips, N., Mayne, R., de Lacy Costello, B., & Adamatzky, A. (2018). Evaporation, Lifetime, and Robustness Studies of Liquid Marbles for Collision-Based Computing. Langmuir, 34(7), 2573-2580. https://doi.org/10.1021/acs.langmuir.7b04196

© 2018 American Chemical Society. Liquid marbles (LMs) have recently attracted interest for use as cargo carriers in digital microfluidics and have successfully been implemented as signal carriers in collision-based unconventional computing circuits.... Read More about Evaporation, Lifetime, and Robustness Studies of Liquid Marbles for Collision-Based Computing.

Mechanical sequential counting with liquid marbles (2018)
Journal Article
Draper, T., Fullarton, C., Phillips, N., de Lacy Costello, B., & Adamatzky, A. (2018). Mechanical sequential counting with liquid marbles. Lecture Notes in Artificial Intelligence, 10867 LNCS, 59-71. https://doi.org/10.1007/978-3-319-92435-9_5

© 2018, Springer International Publishing AG, part of Springer Nature. Here we demonstrate the first working example of a liquid marble-operated sequential binary counting device. We have designed a lightweight gate that can be actuated by the low ma... Read More about Mechanical sequential counting with liquid marbles.

Assessment of a combined gas chromatography mass spectrometer sensor system for detecting biologically relevant volatile compounds (2017)
Journal Article
Gould, O., Ratcliffe, N. M., De Lacy Costello, B., Wieczorek, T., & Persad, R. (2018). Assessment of a combined gas chromatography mass spectrometer sensor system for detecting biologically relevant volatile compounds. Journal of Breath Research, 12(1), 016009. https://doi.org/10.1088/1752-7163/aa8efe

© 2017 IOP Publishing Ltd. There have been a number of studies in which metal oxide sensors (MOS) have replaced conventional analytical detectors in gas chromatography systems. However, despite the use of these instruments in a range of applications... Read More about Assessment of a combined gas chromatography mass spectrometer sensor system for detecting biologically relevant volatile compounds.

Liquid marble interaction gate for collision-based computing (2017)
Journal Article
de Lacy Costello, B. P., Draper, T. C., Draper, T., Fullarton, C., Phillips, N., de Lacy Costello, B., & Adamatzky, A. (2017). Liquid marble interaction gate for collision-based computing. Materials Today, 20(10), 561-568. https://doi.org/10.1016/j.mattod.2017.09.004

© 2017 Elsevier Ltd Liquid marbles are microliter droplets of liquid, encapsulated by self-organized hydrophobic particles at the liquid/air interface. They offer an efficient approach for manipulating liquid droplets and compartmentalizing reactions... Read More about Liquid marble interaction gate for collision-based computing.

Irritable bowel syndrome and active inflammatory bowel disease diagnosed by faecal gas analysis (2016)
Journal Article
de Lacy Costello, B., White, P., Aggio, R. B., White, P., Jayasena, H., de Lacy Costello, B., …Probert, C. S. (2017). Irritable bowel syndrome and active inflammatory bowel disease diagnosed by faecal gas analysis. Alimentary Pharmacology and Therapeutics, 45(1), 82-90. https://doi.org/10.1111/apt.13822

© 2016 John Wiley & Sons Ltd Background: Inflammatory bowel disease and irritable bowel syndrome may present in a similar manner. Measuring faecal calprotectin concentration is often recommended to rule out inflammatory bowel disease, however, ther... Read More about Irritable bowel syndrome and active inflammatory bowel disease diagnosed by faecal gas analysis.

Practical circuits with Physarum Wires (2016)
Journal Article
Whiting, J. G., Whiting, J., Mayne, R., Moody, N., de Lacy Costello, B., & Adamatzky, A. (2016). Practical circuits with Physarum Wires. Biomedical Engineering Letters, 6(2), 57-65. https://doi.org/10.1007/s13534-016-0212-8

© 2016, Korean Society of Medical and Biological Engineering and Springer. Purpose: Protoplasmic tubes of Physarum polycephalum, also know as Physarum Wires (PW), have been previously suggested as novel bio-electronic components. Until recently, prac... Read More about Practical circuits with Physarum Wires.

Evolving unipolar memristor spiking neural networks (2015)
Journal Article
Howard, G. D., Bull, L., & De Lacy Costello, B. (2015). Evolving unipolar memristor spiking neural networks. Connection Science, 27(4), 397-416. https://doi.org/10.1080/09540091.2015.1080225

© 2015 Taylor & Francis. Neuromorphic computing – brain-like computing in hardware – typically requires myriad complimentary metal oxide semiconductor spiking neurons interconnected by a dense mesh of nanoscale plastic synapses. Memristors are freq... Read More about Evolving unipolar memristor spiking neural networks.

Slime mould memristors (2015)
Journal Article
Gale, E., Adamatzky, A., & de Lacy Costello, B. (2015). Slime mould memristors. BioNanoScience, 5(1), 1-8

In laboratory experiments we demonstrate that protoplasmic tubes of acellular slime mould \emph{Physarum polycephalum} show current versus voltage profiles consistent with memristive systems and that the effect is due to the living protoplasm of the... Read More about Slime mould memristors.

Transfer function of protoplasmic tubes of Physarum polycephalum (2015)
Journal Article
Whiting, J., de Lacy Costello, B., & Adamatzky, A. (2015). Transfer function of protoplasmic tubes of Physarum polycephalum. BioSystems, 128, 48-51. https://doi.org/10.1016/j.biosystems.2015.01.009

The slime mould Physarum polycephalum is a large single celledmyxomycete; its plasmodium consists of tubes which extend to find sources of food. It has been previously shown that the tubes are conductive with a resistance of approximately 3MV, and ha... Read More about Transfer function of protoplasmic tubes of Physarum polycephalum.

The effect of changing electrode metal on solution-processed flexible titanium dioxide memristors (2015)
Journal Article
Gale, E., Pearson, D., Kitson, S., Adamatzky, A., & de Lacy Costello, B. (2015). The effect of changing electrode metal on solution-processed flexible titanium dioxide memristors. Materials Chemistry and Physics, 162, 20-30. https://doi.org/10.1016/j.matchemphys.2015.03.037

Flexible solution-processed memristors show different behaviour dependent on the choice of electrode material. Use of gold for both electrodes leads to switchable WORM (Write Once Read Many times) resistive devices. Use of aluminium for both electrod... Read More about The effect of changing electrode metal on solution-processed flexible titanium dioxide memristors.

Urinary volatile organic compounds for the detection of prostate cancer (2015)
Journal Article
Chan, F. L., Khalid, T., Aggio, R., White, P., de Lacy Costello, B., Persad, R., …Ratcliffe, N. M. (2015). Urinary volatile organic compounds for the detection of prostate cancer. PLoS ONE, 10(11), e0143283. https://doi.org/10.1371/journal.pone.0143283

The aim of this work was to investigate volatile organic compounds (VOCs) emanating from urine samples to determine whether they can be used to classify samples into those from prostate cancer and non-cancer groups. Participants were men referred for... Read More about Urinary volatile organic compounds for the detection of prostate cancer.

Cyclic ortho ester fuel additive (2014)
Patent
Lam, J., Ratcliffe, N. M., de Lacy Costello, B., Repetto, S., Costello, J. F., & Parmenter, D. (2014). Cyclic ortho ester fuel additive. WO/2014/174290

Evolving spiking networks with variable resistive memories (2014)
Journal Article
Gale, E., Howard, G., Howard, G. D., Bull, L., de Lacy Costello, B., & Adamatzky, A. (2014). Evolving spiking networks with variable resistive memories. Evolutionary Computation, 22(1), 79-103. https://doi.org/10.1162/EVCO_a_00103

Neuromorphic computing is a brainlike information processing paradigm that requires adaptive learning mechanisms. A spiking neuro-evolutionary system is used for this purpose; plastic resistive memories are implemented as synapses in spiking neural n... Read More about Evolving spiking networks with variable resistive memories.