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Inactivation of Listeria monocytogenes and Salmonella on stainless steel by a piezoelectric cold atmospheric plasma generator (2021)
Journal Article
Gonzalez-Gonzalez, C. R., Hindle, B. J., Saad, S., & Stratakos, A. C. (2021). Inactivation of Listeria monocytogenes and Salmonella on stainless steel by a piezoelectric cold atmospheric plasma generator. Applied Sciences, 11(8), Article 3567. https://doi.org/10.3390/app11083567

Cold atmospheric pressure plasma (CAP) is a novel non‐thermal technology that is gain-ing increasing importance as a decontamination method. Stainless steel is a widespread food contact surface used in food‐processing environments. In this study, for... Read More about Inactivation of Listeria monocytogenes and Salmonella on stainless steel by a piezoelectric cold atmospheric plasma generator.

CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer (2021)
Journal Article
Uzor, S., Porazinski, S., Li, L., Clark, B., Ajiro, M., Iida, K., …Ladomery, M. (2021). CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer. Scientific Reports, 11(1), Article 7963. https://doi.org/10.1038/s41598-021-86908-6

Dysregulation of alternative splicing is a feature of cancer, both in aetiology and progression. It occurs because of mutations in splice sites or sites that regulate splicing, or because of the altered expression and activity of splice factors and o... Read More about CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer.

‘We tend to get pad happy’: A qualitative study of health practitioners’ perspectives on the quality of continence care for older people in hospital (2021)
Journal Article
Percival, J., Abbott, K., Allain, T., Bradley, R., Cramp, F., Donovan, J. L., …Cotterill, N. (2021). ‘We tend to get pad happy’: A qualitative study of health practitioners’ perspectives on the quality of continence care for older people in hospital. BMJ Open Quality, 10(2), Article e001380. https://doi.org/10.1136/bmjoq-2021-001380

Bladder and bowel control difficulties affect 20% and 10% of the UK population, respectively, touch all age groups and are particularly prevalent in the older (65+ years) population. However, the quality of continence care is often poor, compromising... Read More about ‘We tend to get pad happy’: A qualitative study of health practitioners’ perspectives on the quality of continence care for older people in hospital.

5-aminosalicylic acid inhibits stem cell function in human adenoma derived cells: Implications for chemoprophylaxis in colorectal tumorigenesis (2021)
Journal Article
Dixon, S. W., Collard, T. J., Mortensson, E. M. H., Legge, D. N., Chambers, A. C., Greenhough, A., …Williams, A. C. (2021). 5-aminosalicylic acid inhibits stem cell function in human adenoma derived cells: Implications for chemoprophylaxis in colorectal tumorigenesis. British Journal of Cancer, 124, 1959–1969. https://doi.org/10.1038/s41416-021-01354-5

Background: Most colorectal cancers (CRC) arise sporadically from precursor lesions: colonic polyps. Polyp resection prevents progression to CRC. Risk of future polyps is proportional to the number and size of polyps detected at screening, allowing i... Read More about 5-aminosalicylic acid inhibits stem cell function in human adenoma derived cells: Implications for chemoprophylaxis in colorectal tumorigenesis.

Developing a systematic method for extraction of microplastics in soils (2021)
Journal Article
Radford, F., Zapata-Restrepo, L. M., Horton, A. A., Hudson, M. D., Shaw, P. J., & Williams, I. D. (2021). Developing a systematic method for extraction of microplastics in soils. Analytical Methods, 13(14), 1695-1705. https://doi.org/10.1039/d0ay02086a

Microplastics are an environmental issue of global concern. Although they have been found in a range of environments worldwide, their contamination in the terrestrial environment is poorly understood. The lack of standardised methods for their detect... Read More about Developing a systematic method for extraction of microplastics in soils.

A roadmap for genome-based phage taxonomy (2021)
Journal Article
Turner, D., Kropinski, A. M., & Adriaenssens, E. M. (2021). A roadmap for genome-based phage taxonomy. Viruses, 13(3), Article 506. https://doi.org/10.3390/v13030506

Bacteriophage (phage) taxonomy has been in flux since its inception over four decades ago. Genome sequencing has put pressure on the classification system and recent years have seen significant changes to phage taxonomy. Here, we reflect on the state... Read More about A roadmap for genome-based phage taxonomy.

Brachytherapy for locally advanced cervical cancer: A survey of UK provision of care and support (2021)
Journal Article
Humphrey, P., Dures, E., Hoskin, P., & Cramp, F. (2021). Brachytherapy for locally advanced cervical cancer: A survey of UK provision of care and support. Radiotherapy and Oncology, 159, 60-66. https://doi.org/10.1016/j.radonc.2021.03.007

Background and purpose: Gynaecological brachytherapy can cause anxiety, distress and discomfort. It is not known how variation in delivery impacts women's experiences. To inform future research an online survey was carried out to identify variations... Read More about Brachytherapy for locally advanced cervical cancer: A survey of UK provision of care and support.

Formation of furan in baby food products: Identification and technical challenges (2021)
Journal Article
Javed, F., Shahbaz, H. M., Nawaz, A., Olaimat, A. N., Stratakos, A. C., Wahyono, A., …Park, J. (2021). Formation of furan in baby food products: Identification and technical challenges. Comprehensive Reviews in Food Science and Food Safety, 20(3), 2699-2715. https://doi.org/10.1111/1541-4337.12732

Furan is generally produced during thermal processing of various foods including baked, fried, and roasted food items such as cereal products, coffee, canned, and jarred prepared foods as well as in baby foods. Furan is a toxic and carcinogenic compo... Read More about Formation of furan in baby food products: Identification and technical challenges.

Seeds of change: Establishing frameworks for understanding global environmental changes: This article belongs to Ambio's 50th Anniversary Collection. Theme: Agricultural land use (2021)
Journal Article
Sanderson Bellamy, A. (2021). Seeds of change: Establishing frameworks for understanding global environmental changes: This article belongs to Ambio's 50th Anniversary Collection. Theme: Agricultural land use. AMBIO: A Journal of the Human Environment, 50(7), 1281-1285. https://doi.org/10.1007/s13280-021-01509-x

Recent progress in screen-printed electrochemical sensors and biosensors for the detection of estrogens (2021)
Journal Article
Musa, A. M., Kiely, J., Luxton, R., & Honeychurch, K. C. (2021). Recent progress in screen-printed electrochemical sensors and biosensors for the detection of estrogens. Trends in Analytical Chemistry, 139, Article 116254. https://doi.org/10.1016/j.trac.2021.116254

Estrogens have become increasingly prevalent in environmental samples across the world, posing a serious threat to human health. They have received considerable public attention due to their harmful effect on the normal endocrine functions of humans... Read More about Recent progress in screen-printed electrochemical sensors and biosensors for the detection of estrogens.

Interacting proteins, polymorphisms and the susceptibility of animals to SARS-CoV-2 (2021)
Journal Article
Hancock, J., Rouse, R., Stone, E., & Greenhough, A. (2021). Interacting proteins, polymorphisms and the susceptibility of animals to SARS-CoV-2. Animals, 11(3), Article 797. https://doi.org/10.3390/ani11030797

Abstract: COVID-19, caused by SARS-CoV-2, is a world-wide problem for the human population. It is known that some animal species, such as mink, can become infected and transmit the virus. However, the susceptibility of most animals is not known. Here... Read More about Interacting proteins, polymorphisms and the susceptibility of animals to SARS-CoV-2.

Epigenenetic regulation of alternative splicing: How lncRNAs tailor the message (2021)
Journal Article
Pisignano, G., & Ladomery, M. (2021). Epigenenetic regulation of alternative splicing: How lncRNAs tailor the message. Non-Coding RNA, 7(1), Article 21. https://doi.org/10.3390/ncrna7010021

Alternative splicing is a highly fine-tuned regulated process and one of the main drivers of proteomic diversity across eukaryotes. The vast majority of human multi-exon genes is alternatively spliced in a cell type-and tissue-specific manner, and de... Read More about Epigenenetic regulation of alternative splicing: How lncRNAs tailor the message.

Shaping more resilient and just food systems: Lessons from the COVID-19 Pandemic (2021)
Journal Article
Sanderson Bellamy, A., Furness, E., Nicol, P., Pitt, H., & Taherzadeh, A. (2021). Shaping more resilient and just food systems: Lessons from the COVID-19 Pandemic. AMBIO: A Journal of the Human Environment, 50, 782-793. https://doi.org/10.1007/s13280-021-01532-y

The COVID-19 pandemic has highlighted weaknesses in global food systems, as well as opening windows of opportunity for innovation and transformation. While the nature and extent of this crisis is rare, extreme climatic events will increase in magnitu... Read More about Shaping more resilient and just food systems: Lessons from the COVID-19 Pandemic.

The anti-cancer effect of Olea europaea L. products: A review (2021)
Journal Article
Antoniou, C., & Hull, J. (2021). The anti-cancer effect of Olea europaea L. products: A review. Current Nutrition Reports, 10, 99–124. https://doi.org/10.1007/s13668-021-00350-8

Purpose of Review: The olive tree (Olea europaea L.) has featured as a significant part of medicinal history, used to treat a variety of ailments within folk medicine. The Mediterranean diet, which is rich in olive products, is testament to Olea euro... Read More about The anti-cancer effect of Olea europaea L. products: A review.

Leaf arginine spraying improves leaf gas exchange under water deficit and root antioxidant responses during the recovery period (2021)
Journal Article
Silveira, N. M., Ribeiro, R. V., de Morais, S. F. N., de Souza, S. C. R., da Silva, S. F., Seabra, A. B., …Machado, E. C. (2021). Leaf arginine spraying improves leaf gas exchange under water deficit and root antioxidant responses during the recovery period. Plant Physiology and Biochemistry, 162, 315-326. https://doi.org/10.1016/j.plaphy.2021.02.036

© 2021 Elsevier Masson SAS Arginine (Arg) metabolism is associated with many cellular and developmental processes in plants and proline, nitric oxide (NO) and polyamines (PAs) have a wide range of physiological functions in plants, including increase... Read More about Leaf arginine spraying improves leaf gas exchange under water deficit and root antioxidant responses during the recovery period.

3D scaffolds in the treatment of diabetic foot ulcers: New trends vs conventional approaches (2021)
Journal Article
Glover, K., Ch. Stratakos, A., Varadi, A., & Lamprou, D. A. (2021). 3D scaffolds in the treatment of diabetic foot ulcers: New trends vs conventional approaches. International Journal of Pharmaceutics, 599, https://doi.org/10.1016/j.ijpharm.2021.120423

Diabetic foot ulcer (DFU) is a serious complication of diabetes mellitus, affecting roughly 25% of diabetic patients and resulting in lower limb amputation in over 70% of known cases. In addition to the devastating physiological consequences of DFU a... Read More about 3D scaffolds in the treatment of diabetic foot ulcers: New trends vs conventional approaches.

The UK forensic science regulator: Fit for purpose? (2021)
Journal Article
Nsiah Amoako, E., & McCartney, C. (2021). The UK forensic science regulator: Fit for purpose?. Wiley Interdisciplinary Reviews: Forensic Science, 3(6), e1415. https://doi.org/10.1002/wfs2.1415

The role of Forensic Science Regulator (FSR), created in 2007, was established to assure the achievement and maintenance of forensic science service (FSS) provision that commands public confidence. The FSR works at an organizational level, to assure,... Read More about The UK forensic science regulator: Fit for purpose?.

Alternative mobile phase additives for the characterization of protein biopharmaceuticals in liquid chromatography – Mass spectrometry (2021)
Journal Article
Lardeux, H., Duivelshof, B. L., Colas, O., Beck, A., McCalley, D. V., Guillarme, D., & D’Atri, V. (2021). Alternative mobile phase additives for the characterization of protein biopharmaceuticals in liquid chromatography – Mass spectrometry. Analytica Chimica Acta, 1156, Article 338347. https://doi.org/10.1016/j.aca.2021.338347

When analyzing large complex protein biopharmaceuticals, ion-pairing agents imparting low pH are widely used as mobile phase additives to improve the chromatographic performance. However, one of the most effective additives in RPLC and HILIC, trifluo... Read More about Alternative mobile phase additives for the characterization of protein biopharmaceuticals in liquid chromatography – Mass spectrometry.

Current provision of general practitioner services in or alongside emergency departments in England (2021)
Journal Article
Brant, H., Voss, S., Morton, K., Cooper, A., Edwards, M., Price, D., …Benger, J. (2021). Current provision of general practitioner services in or alongside emergency departments in England. Emergency Medicine Journal, 38(10), 780-783. https://doi.org/10.1136/emermed-2020-210539

Background: In 2017, general practitioners in or alongside the emergency department (GPED), an approach that employs GPs in or alongside the ED to address increasing ED demand, was advocated by the National Health Service in England and supported by... Read More about Current provision of general practitioner services in or alongside emergency departments in England.