All Outputs (25)

The role of satellite image-processing for national-scale estimates of gene flow from genetically modified crops: Rapeseed in the UK as a model (2004)
Journal Article
Elliott, L. J., Mason, D. C., Wilkinson, M. J., Allainguillaume, J., Norris, C., Alexander, M., & Welters, R. (2004). The role of satellite image-processing for national-scale estimates of gene flow from genetically modified crops: Rapeseed in the UK as a model. Journal of Applied Ecology, 41(6), 1174-1184. https://doi.org/10.1111/j.0021-8901.2004.00963.x

1. There is concern over the possibility of unwanted environmental change following transgene movement from genetically modified (GM) rapeseed Brassica napus to its wild and weedy relatives. 2. The aim of this research was to develop a remote sensing... Read More about The role of satellite image-processing for national-scale estimates of gene flow from genetically modified crops: Rapeseed in the UK as a model.

The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone (2004)
Journal Article
Doran, E., Tambyrajah, W. S., Doran (nee Udovikova), O., Wood, J. D., & McGivan, J. D. (2004). The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone. Archives of Biochemistry and Biophysics, 431(2), 252-260. https://doi.org/10.1016/j.abb.2004.08.016

Functional analysis of the pig cytochrome P4502E1 (CYP2E1) promoter identified two major activating elements. One corresponded to the hepatic nuclear factor 1 (HNF-1) consensus binding sequence at nucleotides -128/-98 and the other was located in the... Read More about The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone.

p16INK4a polymorphism: Associations with tumour progression in patients with sporadic colorectal cancer (2004)
Journal Article
McCloud, J. M., Sivakumar, R., Greenhough, A., Elder, J., Jones, P. W., Deakin, M., …Hoban, P. R. (2004). p16INK4a polymorphism: Associations with tumour progression in patients with sporadic colorectal cancer. International Journal of Oncology, 25(5), 1447-1452. https://doi.org/10.3892/ijo.25.5.1447

Deregulated tumour expression of p16INK4a has previously been described in association with clinical progression in sporadic colorectal cancer patients (CRC). Furthermore, p16INK4a promoter hypermethylation leading to gene silencing has been shown to... Read More about p16INK4a polymorphism: Associations with tumour progression in patients with sporadic colorectal cancer.

Fundamental subchondral bone changes in spontaneous knee osteoarthritis (2004)
Journal Article
Anderson-MacKenzie, J. M., Quasnichka, H. L., Starr, R. L., Lewis, E. J., Billingham, M. E., & Bailey, A. J. (2005). Fundamental subchondral bone changes in spontaneous knee osteoarthritis. International Journal of Biochemistry and Cell Biology, 37(1), 224-236. https://doi.org/10.1016/j.biocel.2004.06.016

Osteoarthritis has an unknown aetiology, and tissue samples from early stage human osteoarthritis tissue cannot be reliably obtained. Therefore understanding the development of OA relies on using animal models: such as the spontaneous changes seen in... Read More about Fundamental subchondral bone changes in spontaneous knee osteoarthritis.

Penetrative convection induced by the absorption of radiation with a nonlinear internal heat source (2004)
Journal Article
Hill, A. A. (2004). Penetrative convection induced by the absorption of radiation with a nonlinear internal heat source. Dynamics of Atmospheres and Oceans, 38(1), 57-67. https://doi.org/10.1016/j.dynatmoce.2004.03.002

A model for convection induced by the selective absorption of radiation in a fluid layer is investigated. The concentration based internal heat source is modelled quadratically. A linear analysis and conditional nonlinear analysis are performed. Due... Read More about Penetrative convection induced by the absorption of radiation with a nonlinear internal heat source.

DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines (2004)
Journal Article
Gray, A. G., Morgan, L. M., Avent, N. D., Smith, M. A., Court, E. L., Hancock, J. T., & Smith, J. G. (2004). DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines. Leukemia Research, 28(7), 743-753. https://doi.org/10.1016/j.leukres.2003.11.011

This study used cDNA microarray technology to compare gene expression profiles in acute myeloblastic leukaemia (AML) with cDNA dot-blot and real time PCR analysis of cDNA transcripts to confirm array data. Patient AML marrow samples and AML cell line... Read More about DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines.

Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme (2004)
Journal Article
Conway, M. E., Poole, L. B., & Hutson, S. M. (2004). Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme. Biochemistry, 43(23), 7356-7364. https://doi.org/10.1021/bi0498050

The redox-active dithiol/disulfide C315-Xaa-Xaa-C318 center has been implicated in the regulation of the human mitochondrial branched chain aminotransferase isozyme (hBCATm) [Conway, M. E., Yennawar, N., Wallin, R., Poole, L. B., and Hutson, S. M. (2... Read More about Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme.

Effect of buffer on peak shape of peptides in reversed-phase high performance liquid chromatography (2004)
Journal Article
McCalley, D. V. (2004). Effect of buffer on peak shape of peptides in reversed-phase high performance liquid chromatography. Journal of Chromatography A, 1038(1-2), 77-84. https://doi.org/10.1016/j.chroma.2004.03.038

The effect of changing the buffer at constant low pH in the mobile phase is investigated with respect to the separation of a mixture of basic peptides. Considerably worse peak shapes, leading to poorer resolution of complex peptide mixtures, were obt... Read More about Effect of buffer on peak shape of peptides in reversed-phase high performance liquid chromatography.

Doubling the estimate of invertebrate biomass in a rainforest canopy (2004)
Journal Article
Ellwood, M. D. F., & Foster, W. A. (2004). Doubling the estimate of invertebrate biomass in a rainforest canopy. Nature, 429(6991), 549-551. https://doi.org/10.1038/nature02560

Forest canopies represent the functional interface between 90% of the Earth's terrestrial biomass and the atmosphere and include some of the most threatened of all terrestrial ecosystems. However, we lack even a basic understanding of how the biomass... Read More about Doubling the estimate of invertebrate biomass in a rainforest canopy.

Experimental implementation of mobile robot taxis with onboard Belousov-Zhabotinsky chemical medium (2004)
Journal Article
Ratcliffe, N., Adamatzky, A., Costello, B. D. L., & Melhuish, C. (2004). Experimental implementation of mobile robot taxis with onboard Belousov-Zhabotinsky chemical medium. Materials Science and Engineering: C, 24(4), 541-548. https://doi.org/10.1016/j.msec.2004.02.002

We discuss the first-ever experimental realization of the onboard excitable chemical controller for stimulus-guided navigation of mobile robots. We demonstrate that the Belousov-Zhabotinsky (BZ) reaction in the form of an onboard thin layer chemical... Read More about Experimental implementation of mobile robot taxis with onboard Belousov-Zhabotinsky chemical medium.

Reaction-diffusion navigation robot control: From chemical to VLSI analogic processors (2004)
Journal Article
Rodríguez-Vázquez, A., De Lacy Costello, B., Carmona-Galán, R., Arena, P., Adamatzky, A., Basile, A., …Frasca, M. (2004). Reaction-diffusion navigation robot control: From chemical to VLSI analogic processors. IEEE Transactions on Circuits and Systems I: Regular Papers, 51(5), 926-938. https://doi.org/10.1109/TCSI.2004.827654

We introduce a new methodology and experimental implementations for real-time wave-based robot navigation in a complex, dynamically changing environment. The main idea behind the approach is to consider the robot arena as an excitable medium, in whic... Read More about Reaction-diffusion navigation robot control: From chemical to VLSI analogic processors.

Conditional and unconditional nonlinear stability for convection induced by absorption of radiation in a porous medium (2004)
Journal Article
Hill, A. A. (2004). Conditional and unconditional nonlinear stability for convection induced by absorption of radiation in a porous medium. Continuum Mechanics and Thermodynamics, 16(4), 305-318. https://doi.org/10.1007/s00161-003-0151-3

Convection induced by the selective absorption of radiation is investigated, for the case of an internal heat source that is modelled quadratically with respect to concentration. The growth rate for the linearised system is shown to be real, and a li... Read More about Conditional and unconditional nonlinear stability for convection induced by absorption of radiation in a porous medium.

Use of External Magnetic Fields to Reduce Reaction Times in an Immunoassay Using Micrometer-Sized Paramagnetic Particles as Labels (Magnetoimmunoassay) (2004)
Journal Article
Luxton, R., Badesha, J., Kiely, J., & Hawkins, P. (2004). Use of External Magnetic Fields to Reduce Reaction Times in an Immunoassay Using Micrometer-Sized Paramagnetic Particles as Labels (Magnetoimmunoassay). Analytical Chemistry, 76(6), 1715-1719. https://doi.org/10.1021/ac034906%2B

The paper presents a rapid immunoassay system capable of quantifying analyte in complex biological and environmental media. Antibody-coated micrometer-sized paramagnetic particles are used as labels in an assay in which they bind quantitatively with... Read More about Use of External Magnetic Fields to Reduce Reaction Times in an Immunoassay Using Micrometer-Sized Paramagnetic Particles as Labels (Magnetoimmunoassay).

Voltammetric, chromatographic and mass spectral elucidation of the redox reactions of 1-hydroxypyrene occurring at a screen-printed carbon electrode (2004)
Journal Article
Honeychurch, K. C., Hart, J. P., & Kirsch, N. (2004). Voltammetric, chromatographic and mass spectral elucidation of the redox reactions of 1-hydroxypyrene occurring at a screen-printed carbon electrode. Electrochimica Acta, 49(7), 1141-1149. https://doi.org/10.1016/j.electacta.2003.10.025

The electrochemical oxidation of 1-hydroxypyrene (1-OHP) has been studied at a screen-printed carbon electrode (SPCE), by cyclic voltammetry and bulk electrolysis. Cyclic voltammograms exhibited two quasi-reversible pairs of peaks (designated 1a′/1c... Read More about Voltammetric, chromatographic and mass spectral elucidation of the redox reactions of 1-hydroxypyrene occurring at a screen-printed carbon electrode.

Voronoi diagrams generated by regressing edges of precipitation fronts (2004)
Journal Article
Hantz, P., de Lacy Costello, B., & Ratcliffe, N. M. (2004). Voronoi diagrams generated by regressing edges of precipitation fronts. Journal of Chemical Physics, 120(5), 2413-2416. https://doi.org/10.1063/1.1635358

The Voronoi diagram generated by regression edges of precipitation fronts was analyzed. In the reaction-diffusion system, one of the reagents penetrates into a gel by diffusion and forms a precipitate with the other reagent homogenized in the gel. It... Read More about Voronoi diagrams generated by regressing edges of precipitation fronts.

New equations for redox and nano-signal transduction (2004)
Journal Article
Hancock, J. T., Desikan, R., Neill, S., & Cross, A. R. (2004). New equations for redox and nano-signal transduction. Journal of Theoretical Biology, 226(1), 65-68. https://doi.org/10.1016/j.jtbi.2003.08.003

Cells maintain redox potentials (Eh) in intracellular compartments, sometimes referred to as redox environments. These potentials are often very reducing, for example in the cytoplasm, but throughout the cell different potentials are maintained, comm... Read More about New equations for redox and nano-signal transduction.

Identification by gas chromatography-mass spectrometry of the volatile organic compounds emitted from the wood-rotting fungi Serpula lacrymans and Coniophora puteana, and from Pinus sylvestris timber (2004)
Journal Article
Ewen, R. J., Jones, P. R., Ratcliffe, N. M., & Spencer-Phillips, P. T. (2004). Identification by gas chromatography-mass spectrometry of the volatile organic compounds emitted from the wood-rotting fungi Serpula lacrymans and Coniophora puteana, and from Pinus sylvestris timber. Mycological Research, 108(7), 806-814. https://doi.org/10.1017/S095375620400022X

Volatile organic compounds (VOCs) emitted by two wood-rotting basidiomycete fungi, Serpula lacrymans (dry rot fungus) and Coniophora puteana (cellar fungus), and the timber of Pinus sylvestris (Scots pine), were identified. Several volatile collectio... Read More about Identification by gas chromatography-mass spectrometry of the volatile organic compounds emitted from the wood-rotting fungi Serpula lacrymans and Coniophora puteana, and from Pinus sylvestris timber.

The use of cell line standards to reduce HER-2/neu assay variation in multiple European cancer centres and the potential of automated image analysis to provide for more accurate cut points for predicting clinical response to trastuzumab (2004)
Journal Article
Rhodes, A., Borthwick, D., Sykes, R., Al-Sam, S., & Paradiso, A. (2004). The use of cell line standards to reduce HER-2/neu assay variation in multiple European cancer centres and the potential of automated image analysis to provide for more accurate cut points for predicting clinical response to trastuzumab. American Journal of Clinical Pathology, 122, 51-60. https://doi.org/10.1309/E9B5-5JYH-D84L-8Y17

Hydrogen peroxide is a common signal for darkness and ABA-induced stomatal closure in Pisum sativum L. (2004)
Journal Article
Desikan, R., Cheung, M., Clarke, A., Golding, S., Sagi, M., Fluhr, R., …Neill, S. (2004). Hydrogen peroxide is a common signal for darkness and ABA-induced stomatal closure in Pisum sativum L. Functional Plant Biology, 31(9), 913-920

The requirement for hydrogen peroxide (H2O2) generation and action during stomatal closure induced by darkness and abscisic acid (ABA) was investigated in pea (Pisum sativum L.). Stomatal closure induced by darkness or ABA was inhibited by the H2O2-s... Read More about Hydrogen peroxide is a common signal for darkness and ABA-induced stomatal closure in Pisum sativum L..

Convection induced by the selective absorption of radiation for the Brinkman model (2004)
Journal Article
Hill, A. A. (2004). Convection induced by the selective absorption of radiation for the Brinkman model. Continuum Mechanics and Thermodynamics, 16(1-2), 43-52. https://doi.org/10.1007/s00161-003-0140-6

Convection induced by the selective absorption of radiation in a porous medium is studied analytically and numerically using the Brinkman model. Both linear instability analysis and nonlinear stability analysis are employed. The thresholds show excel... Read More about Convection induced by the selective absorption of radiation for the Brinkman model.