All Outputs (97)

Evolving unipolar memristor spiking neural networks (2015)
Journal Article
Howard, G. D., Bull, L., & De Lacy Costello, B. (2015). Evolving unipolar memristor spiking neural networks. Connection Science, 27(4), 397-416. https://doi.org/10.1080/09540091.2015.1080225

© 2015 Taylor & Francis. Neuromorphic computing – brain-like computing in hardware – typically requires myriad complimentary metal oxide semiconductor spiking neurons interconnected by a dense mesh of nanoscale plastic synapses. Memristors are freq... Read More about Evolving unipolar memristor spiking neural networks.

The effect of changing electrode metal on solution-processed flexible titanium dioxide memristors (2015)
Journal Article
Gale, E., Pearson, D., Kitson, S., Adamatzky, A., & De Lacy Costello, B. (2015). The effect of changing electrode metal on solution-processed flexible titanium dioxide memristors. Materials Chemistry and Physics, 162, 20-30. https://doi.org/10.1016/j.matchemphys.2015.03.037

© 2015 Elsevier B.V. Abstract Flexible solution-processed memristors show different behaviour dependent on the choice of electrode material. Use of gold for both electrodes leads to switchable WORM (Write Once Read Many times) resistive devices. Use... Read More about The effect of changing electrode metal on solution-processed flexible titanium dioxide memristors.

Slime mould memristors (2015)
Journal Article
Gale, E., Adamatzky, A., & de Lacy Costello, B. (2015). Slime mould memristors. BioNanoScience, 5(1), 1-8

In laboratory experiments we demonstrate that protoplasmic tubes of acellular slime mould \emph{Physarum polycephalum} show current versus voltage profiles consistent with memristive systems and that the effect is due to the living protoplasm of the... Read More about Slime mould memristors.

Transfer function of protoplasmic tubes of Physarum polycephalum (2015)
Journal Article
de Lacy Costello, B. P., Whiting, J. G. H., de Lacy Costello, B., & Adamatzky, A. (2015). Transfer function of protoplasmic tubes of Physarum polycephalum. BioSystems, 128, 48-51. https://doi.org/10.1016/j.biosystems.2015.01.009

© 2015. The slime mould Physarum polycephalum is a large single celled myxomycete; its plasmodium consists of tubes which extend to find sources of food. It has been previously shown that the tubes are conductive with a resistance of approximately 3.... Read More about Transfer function of protoplasmic tubes of Physarum polycephalum.

Towards point of care testing for C. difficile infection by volatile profiling, using the combination of a short multi-capillary gas chromatography column with metal oxide sensor detection (2014)
Journal Article
Vaughan, K., Probert, C. S., Garner, C. E., McGuire, N. D., Ewen, R. J., de Lacy Costello, B., & Ratcliffe, N. M. (2014). Towards point of care testing for C. difficile infection by volatile profiling, using the combination of a short multi-capillary gas chromatography column with metal oxide sensor detection. Measurement Science and Technology, 25(6), https://doi.org/10.1088/0957-0233/25/6/065108

Rapid volatile profiling of stool sample headspace was achieved using a combination of short multi-capillary chromatography column (SMCC), highly sensitive heated metal oxide semiconductor sensor and artificial neural network software. For direct ana... Read More about Towards point of care testing for C. difficile infection by volatile profiling, using the combination of a short multi-capillary gas chromatography column with metal oxide sensor detection.

Slime mould logic gates based on frequency changes of electrical potential oscillation (2014)
Journal Article
Whiting, J. G. H., de Lacy Costello, B. P. J., & Adamatzky, A. (2014). Slime mould logic gates based on frequency changes of electrical potential oscillation. BioSystems, 124, 21-25. https://doi.org/10.1016/j.biosystems.2014.08.001

Physarum polycephalum is a large single amoeba cell, which in its plasmodial phase, forages and connects nearby food sources with protoplasmic tubes. The organism forages for food by growing these tubes towards detected foodstuff, this foraging behav... Read More about Slime mould logic gates based on frequency changes of electrical potential oscillation.

Emergent spiking in non-ideal memristor networks (2014)
Journal Article
Costello, B. D. L., Gale, E., de Lacy Costello, B., & Adamatzky, A. (2014). Emergent spiking in non-ideal memristor networks. Microelectronics Journal, 45(11), 1401-1415. https://doi.org/10.1016/j.mejo.2014.06.008

© 2014 Elsevier Ltd. All rights reserved. Memristors have uses as artificial synapses and perform well in this role in simulations with artificial spiking neurons. Our experiments show that memristor networks natively spike and can exhibit emergent o... Read More about Emergent spiking in non-ideal memristor networks.

Sensory fusion in Physarum polycephalum and implementing multi-sensory functional computation (2014)
Journal Article
Whiting, J., de Lacy Costello, B., & Adamatzky, A. (2014). Sensory fusion in Physarum polycephalum and implementing multi-sensory functional computation. BioSystems, 119(1), 45-52. https://doi.org/10.1016/j.biosystems.2014.03.003

Surface electrical potential and observational growth recordings were made of a protoplasmic tube of the slime mould Physarum polycephalum in response to a multitude of stimuli with regards to sensory fusion or multisensory integration. Each stimulus... Read More about Sensory fusion in Physarum polycephalum and implementing multi-sensory functional computation.

The use of a gas chromatograph coupled to a metal oxide sensor for rapid assessment of stool samples from irritable bowel syndrome and inflammatory bowel disease patients (2014)
Journal Article
Vaughan, K., Shepherd, S. F., McGuire, N. D., de Lacy Costello, B., Ewen, R. J., Jayasena, D. H., …Ratcliffe, N. M. (2014). The use of a gas chromatograph coupled to a metal oxide sensor for rapid assessment of stool samples from irritable bowel syndrome and inflammatory bowel disease patients. Journal of Breath Research, 8(2), https://doi.org/10.1088/1752-7155/8/2/026001

There is much clinical interest in the development of a low-cost and reliable test for diagnosing inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), two very distinct diseases that can present with similar symptoms. The assessment o... Read More about The use of a gas chromatograph coupled to a metal oxide sensor for rapid assessment of stool samples from irritable bowel syndrome and inflammatory bowel disease patients.

Drop-coated titanium dioxide memristors (2013)
Journal Article
Gale, E., Mayne, R., Adamatzky, A., & De Lacy Costello, B. (2014). Drop-coated titanium dioxide memristors. Materials Chemistry and Physics, 143(2), 524-529. https://doi.org/10.1016/j.matchemphys.2013.09.013

The fabrication of memristors by drop-coating sol-gel Ti(OH)4 solution onto either aluminium foil or sputter-coated aluminium on plastic is presented. The gel layer is thick, 37 μm, but both devices exhibit good memristance I-V profiles. The drop coa... Read More about Drop-coated titanium dioxide memristors.

Towards slime mould chemical sensor: Mapping chemical inputs onto electrical potential dynamics of Physarum Polycephalum (2013)
Journal Article
Whiting, J. G. H., de Lacy Costello, B. P. J., & Adamatzky, A. (2014). Towards slime mould chemical sensor: Mapping chemical inputs onto electrical potential dynamics of Physarum Polycephalum. Sensors and Actuators B: Chemical, 191, 844-853. https://doi.org/10.1016/j.snb.2013.10.064

Plasmodium of slime mould Physarum polycephalum is a large single celled organism visible unaided by the eye. This slime mould is capable of optimising the shape of its protoplasmic networks in spatial configurations of attractants and repellents. Su... Read More about Towards slime mould chemical sensor: Mapping chemical inputs onto electrical potential dynamics of Physarum Polycephalum.

Breath volatile analysis from patients diagnosed with harmful drinking, cirrhosis and hepatic encephalopathy: A pilot study (2013)
Journal Article
Ratcliffe, N. M., Costello, B. D. L., Khalid, T. Y., de Lacy Costello, B., Ewen, R., White, P., …Probert, C. S. (2013). Breath volatile analysis from patients diagnosed with harmful drinking, cirrhosis and hepatic encephalopathy: A pilot study. Metabolomics, 9(5), 938-948. https://doi.org/10.1007/s11306-013-0510-4

Hepatic encephalopathy (HE) is a neuropsychiatric state potentially complicating cirrhosis following the accumulation of toxic compounds that cross the blood-brain barrier and affect brain function; the compounds may undergo alveolar gas exchange and... Read More about Breath volatile analysis from patients diagnosed with harmful drinking, cirrhosis and hepatic encephalopathy: A pilot study.

The Development of Novel Fuel Dehydrating Icing Inhibitors (2013)
Journal Article
Lam, J. K., de Lacy Costello, B., Repetto, S. L., Repetto, S., Costello, J. F., de Lacy Costello, B., …Lam, J. (2013). The Development of Novel Fuel Dehydrating Icing Inhibitors. SAE International Journal of Fuels and Lubricants, 6(3), 553-563. https://doi.org/10.4271/2013-01-2169

Dissolved water is a normal component of jet fuel which is vapourised during combustion; however, free water is a contaminant that can starve engines, freeze to form ice crystals capable of blocking fuel feeds, support microbial growth, and contribut... Read More about The Development of Novel Fuel Dehydrating Icing Inhibitors.

An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS (2013)
Journal Article
Ratcliffe, N., De Lacy Costello, B., Al-Kateb, H., de Lacy Costello, B., & Ratcliffe, N. M. (2013). An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS. Journal of Breath Research, 7(3), https://doi.org/10.1088/1752-7155/7/3/036004

Analysis of volatile organic compounds (VOCs) from saliva, to aid disease diagnoses, has received little attention. This work aims to address the paucity of information on saliva volatiles and includes a database of newly identified compounds whilst... Read More about An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS.

A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace (2013)
Journal Article
Ratcliffe, N., Probert, C. S., Ewen, R., Khalid, T., White, P., De Lacy Costello, B., …Ratcliffe, N. M. (2013). A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace. PLoS ONE, 8(7), https://doi.org/10.1371/journal.pone.0069602

There is a need to reduce the number of cystoscopies on patients with haematuria. Presently there are no reliable biomarkers to screen for bladder cancer. In this paper, we evaluate a new simple in-house fabricated, GC-sensor device in the diagnosis... Read More about A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace.

Observation, characterization and modeling of memristor current spikes (2013)
Journal Article
Gale, E., de Lacy Costello, B., & Adamatzky, A. (2013). Observation, characterization and modeling of memristor current spikes. https://doi.org/10.12785/amis/070418

Memristors have been compared to neurons (usually specifically the synapses) since 1976 but no experimental evidence has been offered for support for this position. Here we highlight that memristors naturally form fast-response, highly reproducible a... Read More about Observation, characterization and modeling of memristor current spikes.

The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease (2013)
Journal Article
Ratcliffe, N. M., de Lacy Costello, B., & Shepherd, S. (2013). The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease. Clinical laboratory international, 37, 18-20

Currently, the diagnosis of bowel diseases such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) relies on invasive and expensive procedures. Identification of biomarker-based tests to aid diagnosis is an important area of resea... Read More about The use of MS for the investigation of irritable bowel syndrome and inflammatory bowel disease.

An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome (2013)
Journal Article
Probert, C. S., de Costello, B. L., Ahmed, I., Greenwood, R., de Lacy Costello, B., Ratcliffe, N. M., & Probert, C. (2013). An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome. PLoS ONE, 8(3), https://doi.org/10.1371/journal.pone.0058204

Diagnosing irritable bowel syndrome (IBS) can be a challenge; many clinicians resort to invasive investigations in order to rule out other diseases and reassure their patients. Volatile organic metabolites (VOMs) are emitted from feces; understanding... Read More about An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome.

Volatiles from oral anaerobes confounding breath biomarker discovery (2013)
Journal Article
De Lacy Costello, B., Khalid, T. Y., Ratcliffe, N. M., Khalid, T., Saad, S., Greenman, J., …Ratcliffe, N. M. (2013). Volatiles from oral anaerobes confounding breath biomarker discovery. Journal of Breath Research, 7(1), https://doi.org/10.1088/1752-7155/7/1/017114

The levels of compounds in exhaled mouth air do not necessarily reflect levels in the systemic circulation as bacteria can bio-transform substrates to produce compounds within the mouth. This should be of concern to researchers measuring breath volat... Read More about Volatiles from oral anaerobes confounding breath biomarker discovery.

Evolution of plastic learning in spiking networks via memristive connections (2012)
Journal Article
Howard, G., Howard, D., Gale, E., Bull, L., De Lacy Costello, B., & Adamatzky, A. (2012). Evolution of plastic learning in spiking networks via memristive connections. IEEE Transactions on Evolutionary Computation, 16(5), 711-729. https://doi.org/10.1109/TEVC.2011.2170199

This paper presents a spiking neuroevolutionary system which implements memristors as plastic connections, i.e., whose weights can vary during a trial. The evolutionary design process exploits parameter self-adaptation and variable topologies, allowi... Read More about Evolution of plastic learning in spiking networks via memristive connections.