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Biological computing using perfusion anodophile biofilm electrodes (PABE) (2008)
Journal Article
Greenman, J., Ieropoulos, I., & Melhuish, C. (2008). Biological computing using perfusion anodophile biofilm electrodes (PABE). International Journal of Unconventional Computing, 4(1), 23-32

This paper presents a theoretical approach to biological computing, using biofilm electrodes by illustrating a simplified Pavlovian learning model. The theory behind this approach was based on empirical data produced from a prototype version of these... Read More about Biological computing using perfusion anodophile biofilm electrodes (PABE).

Effects of chlorhexidine on a tongue-flora microcosm and VSC production using an in vitro biofilm perfusion model (2008)
Journal Article
Greenman, J., McKenzie, C., Saad, S., Wiegand, B., & Zguris, J. C. (2008). Effects of chlorhexidine on a tongue-flora microcosm and VSC production using an in vitro biofilm perfusion model. Journal of Breath Research, 2(4), 046005. https://doi.org/10.1088/1752-7155/2/4/046005

An in vitro perfusion biofilm model, derived from tongue-scrape microflora removed from one individual, was employed to study sulfide biogenesis and the effects of repeated exposure to chlorhexidine (CHX). Volatile sulfur compounds (VSC) were measure... Read More about Effects of chlorhexidine on a tongue-flora microcosm and VSC production using an in vitro biofilm perfusion model.

Penetrative convection in a fluid layer with throughflow (2008)
Journal Article
Capone, F., Gentile, M., & Hill, A. A. (2008). Penetrative convection in a fluid layer with throughflow. Ricerche di matematica, 57(2), 251-260. https://doi.org/10.1007/s11587-008-0035-8

Linear and nonlinear stability analyses of vertical throughflow in a fluid layer, where the density is quadratic in temperature, are studied. To avoid the loss of key terms a weighted functional is used in the energy analysis. Both conditional and un... Read More about Penetrative convection in a fluid layer with throughflow.

Proteomic analysis of a compatible interaction between Pisum sativum (pea) and the downy mildew pathogen Peronospora viciae (2008)
Book Chapter
Lewis, M., Amey, R., Schleicher, T., Slinn, J., Lewis, M., Macdonald, H., …Spencer-Phillips, P. T. (2008). Proteomic analysis of a compatible interaction between Pisum sativum (pea) and the downy mildew pathogen Peronospora viciae. In A. Lebeda, P. T. Spencer-Phillips, & B. Cooke (Eds.), The Downy Mildews - Genetics, Molecular Biology and Control (41-55). Springer Netherlands. https://doi.org/10.1007/978-1-4020-8973-2_5

A proteomic approach was used to identify host proteins altering in abundance during Peronospora viciae infection of a susceptible cultivar of pea (Pisum sativum cv. Livioletta). Proteins were extracted from fully developed pea leaflets at 4 days pos... Read More about Proteomic analysis of a compatible interaction between Pisum sativum (pea) and the downy mildew pathogen Peronospora viciae.

Redox regulation and trapping sulphenic acid in the peroxide sensitive human mitochondrial branched chain aminotransferase (2008)
Journal Article
Coles, S., Hutson, S. M., Poole, L. B., & Conway, M. E. (2008). Redox regulation and trapping sulphenic acid in the peroxide sensitive human mitochondrial branched chain aminotransferase. Methods in Molecular Biology, 476, 139-152. https://doi.org/10.1007/978-1-59745-129-1_10

The human branched chain aminotransferase enzymes are key regulators of glutamate metabolism in the brain and are among a growing number of redox-sensitive proteins. Studies that use thiol-specific reagents and electrospray ionization mass spectromet... Read More about Redox regulation and trapping sulphenic acid in the peroxide sensitive human mitochondrial branched chain aminotransferase.

Dynamic control and information processing in the Belousov-Zhabotinsky reaction using a coevolutionary algorithm (2008)
Journal Article
Toth, R., Stone, C., Adamatzky, A., De Lacy Costello, B., & Bull, L. (2008). Dynamic control and information processing in the Belousov-Zhabotinsky reaction using a coevolutionary algorithm. Journal of Chemical Physics, 129(18), 184708. https://doi.org/10.1063/1.2932252

We propose that the behavior of nonlinear media can be controlled dynamically through coevolutionary systems. In this study, a light-sensitive subexcitable Belousov-Zhabotinsky reaction is controlled using a heterogeneous cellular automaton. A checke... Read More about Dynamic control and information processing in the Belousov-Zhabotinsky reaction using a coevolutionary algorithm.

Effect of sex steroids on expression of sulfotransferase 2B1 immunoreactive protein in primary cultured porcine hepatocytes (2008)
Journal Article
Panella-Riera, N., Moe, M., Grindflek, E., Oliver, M. A., Wood, J. D., & Doran, O. (2008). Effect of sex steroids on expression of sulfotransferase 2B1 immunoreactive protein in primary cultured porcine hepatocytes. Livestock Science, 118(3), 223-230. https://doi.org/10.1016/j.livsci.2008.01.021

An excessive accumulation of androstenone (5α-androst-16-en-3-one) in pig adipose tissue is one of the two major contributors to the phenomenon of boar taint. High levels of adipose tissue androstenone have been related to a low rate of hepatic andro... Read More about Effect of sex steroids on expression of sulfotransferase 2B1 immunoreactive protein in primary cultured porcine hepatocytes.

Physical and biological controls on the in situ kinetic isotope effect associated with oxidation of atmospheric CH4 in mineral soils (2008)
Journal Article
Hornibrook, E. R., Maxfield, P. .. J. .., & Evershed, R. P. (2008). Physical and biological controls on the in situ kinetic isotope effect associated with oxidation of atmospheric CH4 in mineral soils. Environmental Science and Technology, 42(21), 7824-7830. https://doi.org/10.1021/es800544q

The amounts and δ13C values of CH4 at subambient concentrations in soil gas were determined along depth profiles in a U.K. grassland (Bronydd Mawr) and woodland (Leigh Woods). The data were used to determine in situ kinetic isotope effects (KIEs) ass... Read More about Physical and biological controls on the in situ kinetic isotope effect associated with oxidation of atmospheric CH4 in mineral soils.

Investigation of the effect of pressure on retention of small molecules using reversed-phase ultra-high-pressure liquid chromatography (2008)
Journal Article
Fallas, M. M., Neue, U. D., Hadley, M. R., & McCalley, D. V. (2008). Investigation of the effect of pressure on retention of small molecules using reversed-phase ultra-high-pressure liquid chromatography. Journal of Chromatography A, 1209(1-2), 195-205. https://doi.org/10.1016/j.chroma.2008.09.021

The effect of inlet pressure on the retention of a series of low molecular weight acids, bases and neutrals, was investigated at constant temperature in reversed-phase liquid chromatography using a commercial ultra-high-pressure system (Waters UPLC i... Read More about Investigation of the effect of pressure on retention of small molecules using reversed-phase ultra-high-pressure liquid chromatography.

Microbial fuel cells based on carbon veil electrodes: Stack configuration and scalability (2008)
Journal Article
Ieropoulos, I., Greenman, J., & Melhuish, C. (2008). Microbial fuel cells based on carbon veil electrodes: Stack configuration and scalability. International Journal of Energy Research, 32(13), 1228-1240. https://doi.org/10.1002/er.1419

The aim of this study was to compare the performance of three different sizes of microbial fuel cell (MFC) when operated under continuous flow conditions using acetate as the fuel substrate and show how small-scale multiple units may be best configur... Read More about Microbial fuel cells based on carbon veil electrodes: Stack configuration and scalability.

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors (2008)
Journal Article
Amin, E. M., Nowak, D. G., Woolard, J., Konopatskaya, O., Saleem, M. A., Churchill, A. J., …Bates, D. O. (2008). Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors. Journal of Cell Science, 121(20), 3487-3495. https://doi.org/10.1242/jcs.016410

Vascular endothelial growth factor A (VEGFA; hereafter referred to as VEGF) is a key regulator of physiological and pathological angiogenesis. Two families of VEGF isoforms are generated by alternate splice-site selection in the terminal exon. Proxim... Read More about Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors.

The role of redox in signal transduction (2008)
Book Chapter
Hancock, J. T. (2008). The role of redox in signal transduction. In J. T. Hancock (Ed.), Redox-Mediated Signal Transduction: Methods and Protocols (1-9). Humana Press

Disturbance in energy metabolism induced by diclofenac, isoniazid, paracetamol and galactosamine in a liver spheroid model (2008)
Presentation / Conference
Xu, J. (2008, October). Disturbance in energy metabolism induced by diclofenac, isoniazid, paracetamol and galactosamine in a liver spheroid model. Presented at EHRLICH II 2nd World Conference on Magic Bullets, Nurnberg, Germany

The liver plays a central role in the metabolism and transformation of energy-generating substances. Mitochondria and different metabolic pathways in hepatocytes interrelate and are often vulnerable targets of toxicants. Using animal tests it is diff... Read More about Disturbance in energy metabolism induced by diclofenac, isoniazid, paracetamol and galactosamine in a liver spheroid model.