Skip to main content

Research Repository

Advanced Search

Professor Emmanuel Adukwu's Outputs (93)

Effectiveness of infection prevention and control interventions in health care facilities in Africa: A systematic review (2024)
Journal Article

Background Healthcare associated infections (HAIs) are a major threat to patient safety and quality care. However, they are avoidable by implementing evidence-based infection prevention and control measures. This re... Read More about Effectiveness of infection prevention and control interventions in health care facilities in Africa: A systematic review.

The effects of glucose supplementation on the development of Acinetobacter baumannii biofilms (2024)
Presentation / Conference Contribution

The Effect of Glucose on The Development of Acinetobacter baumannii Biofilm

Background: Acinetobacter baumannii, is an opportunistic pathogen causing pneumonia, bacteraemia, wound and urinary tract infections with high mortality rates due to multi... Read More about The effects of glucose supplementation on the development of Acinetobacter baumannii biofilms.

Detection and quantitative microbial risk assessment of pathogenic Vibrio cholerae in a river used for drinking, domestic, fresh produce irrigation and recreational purposes (2024)
Journal Article

Cholera infection results from the ingestion of water or food contaminated with toxigenic Vibrio cholerae. This study evaluated the occurrence of toxigenic V. cholerae in Asata River, Enugu Metropolis, Nigeria, and estimated V. cholerae infection ris... Read More about Detection and quantitative microbial risk assessment of pathogenic Vibrio cholerae in a river used for drinking, domestic, fresh produce irrigation and recreational purposes.

Comparison of the effects of antibiotics and essential oils against Acinetobacter baumannii in planktonic and biofilm conditions (2023)
Presentation / Conference Contribution

Background: Acinetobacter baumannii is a common nosocomial pathogen causing pneumonia, bacteraemia, wound and urinary tract infections. Due to improper and frequent antibiotic use A. baumannii has become multi-drug resistant, the World Health Organi... Read More about Comparison of the effects of antibiotics and essential oils against Acinetobacter baumannii in planktonic and biofilm conditions.

PhD candidate? Why and how to develop a career plan (2023)
Journal Article

After several conversations with some PhD students/candidates, I was struck by one common thread – the lack of awareness or astuteness in planning or developing their own careers, and lack of confidence in seeking help.

Variations in bacteriological and physicochemical water quality characteristics of Asata River, Enugu, Nigeria (2023)
Journal Article

Background and Objective: Globally, river water remains an important source of water for drinking, domestic and other uses. This study aimed to assess the bacteriological and physicochemical properties of Asata River water. Materials and Methods: A... Read More about Variations in bacteriological and physicochemical water quality characteristics of Asata River, Enugu, Nigeria.

I care (2022)
Exhibition / Performance

Inspiring Stories by Inspiring People took place on 31 October 2022. The showcase of Black Professionals in the College of Health, Science & Sciety at UWE Bristol was organised as part of Black History Month.

A featured short film was ‘I Care’, a... Read More about I care.

Celebrating Excellence (2022)
Physical Artefact

Inspiring Stories of Excellence: A Showcase of Black Heritage Professionals in the College of Health, Science & Society at UWE Bristol

Black History Month (BHM) presents an opportunity to celebrate the
achievements and history of Black people and... Read More about Celebrating Excellence.

Effectiveness of the human oral microbe identification microarray in identifying periodontal pathogens: A Systematic review (2022)
Journal Article

The aim of this review was to investigate the effectiveness of the Human Oral Microbe Identification Microarray (HOMIM) in identifying and quantifying bacterial species of the oral microbiome in periodontal disease. The search for articles was conduc... Read More about Effectiveness of the human oral microbe identification microarray in identifying periodontal pathogens: A Systematic review.

Evaluation of microbial viability and nucleic acid integrity after exposure to new molecular transport medium (Σ-MM™) (2022)
Report

A range of organisms (bacteria and yeasts) were inoculated into Sigma MMTM. The inoculum was then aliquoted into TSB broth at 1 minute and 2 minutes to assess for turbidity indicating growth over a 10 day period. A separate aliquot was also removed f... Read More about Evaluation of microbial viability and nucleic acid integrity after exposure to new molecular transport medium (Σ-MM™).

Recent advances in the application of essential oils as potential therapeutic candidates for Candida-related infections (2022)
Journal Article

Candidiasis (oral, vulvovaginal, or systemic bloodstream infections) are important human fungal infections associated with a high global prevalence in otherwise healthy adults but are also opportunistic infections in immunocompromised patients. With... Read More about Recent advances in the application of essential oils as potential therapeutic candidates for Candida-related infections.

Prevalence, distribution and antimicrobial susceptibility pattern of bacterial isolates from a tertiary Hospital in Malawi (2021)
Journal Article

Background: Bacterial infections are a significant cause of sickness and death in sub-Saharan Africa. This study aimed at establishing the prevalence, distribution and antimicrobial susceptibility pattern of major bacterial isolates from patients acc... Read More about Prevalence, distribution and antimicrobial susceptibility pattern of bacterial isolates from a tertiary Hospital in Malawi.

Investigation of the antifungal and anti-aflatoxigenic potential of plant-based essential oils against aspergillus flavus in peanuts (2020)
Journal Article

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Aspergillus species are known to cause damage to food crops and are associated with opportunistic infections in humans. In the United States, significant losses have been reported in peanut pr... Read More about Investigation of the antifungal and anti-aflatoxigenic potential of plant-based essential oils against aspergillus flavus in peanuts.

Evaluation of antimicrobial activity of Curcuma longa L. against beneficial and pathogenic human gastrointestinal microorganisms (2020)
Presentation / Conference Contribution

Introduction: Curcuma longa L. (turmeric) is very popular worldwide as a spice, food preservative, and colouring material. Curcuminoids and turmerones are two major chemical components of turmeric. Many studies have been conducted to test the antimic... Read More about Evaluation of antimicrobial activity of Curcuma longa L. against beneficial and pathogenic human gastrointestinal microorganisms.

Laboratory evaluation of the Sigma Transwab® transport system for the recovery of Candida species using the Clinical and Laboratory Standards Institute (CLSI) document M40-A2 (2020)
Journal Article

Rising healthcare complications due to fungal infections increase the importance of efficient specimen collection and maintenance systems for correct identification and diagnosis. The CLSI M40-A2 protocol provides guidelines for laboratories assessin... Read More about Laboratory evaluation of the Sigma Transwab® transport system for the recovery of Candida species using the Clinical and Laboratory Standards Institute (CLSI) document M40-A2.

In vitro antifungal activity of Cinnamomum zeylanicum bark and leaf essential oils against Candida albicans and Candida auris (2020)
Journal Article

Candida infections are a significant source of patient morbidity and mortality. Candida albicans is the most common pathogen causing Candida infections. Candida auris is a newly described pathogen that is associated with multi-drug-resistant candidia... Read More about In vitro antifungal activity of Cinnamomum zeylanicum bark and leaf essential oils against Candida albicans and Candida auris.

An overview of SARS-CoV-2 (COVID-19) infection and the importance of molecular hydrogen as an adjunctive therapy (2020)
Journal Article

SARS-CoV-2 is an emerging β-coronavirus that causes COVID-19 disease that manifests primarily as a pulmonary infection that can rapidly progress into severe and acute respiratory distress in susceptible patients. Initial reports of severe pulmonary i... Read More about An overview of SARS-CoV-2 (COVID-19) infection and the importance of molecular hydrogen as an adjunctive therapy.

Evaluation of antifungal activities and antihaemolytic effects of cinnamon essential oils from leaf and bark on Candida albicans and Candida auris (2019)
Presentation / Conference Contribution

Candida infections can be considered as a significant source of patient morbidity and mortality. Candida albicans is the most common pathogen causing Candida infections. Candida auris is a newly described pathogen that is associated with multi-drug r... Read More about Evaluation of antifungal activities and antihaemolytic effects of cinnamon essential oils from leaf and bark on Candida albicans and Candida auris.

The 2013-2016 Ebola epidemic: Evaluating communication strategies between two affected countries in West Africa (2019)
Journal Article

Background: Ebola is a haemorrhagic disease with high fatality rates between 25 and 90%. The 2013-16 Ebola outbreak in West Africa was the largest to date with >28 000 cases and >11 000 fatalities. This outbreak exposed inadequacies in public health... Read More about The 2013-2016 Ebola epidemic: Evaluating communication strategies between two affected countries in West Africa.

Exchange (2018)
Exhibition / Performance

In vitro antimicrobial activity of Cymbopogon flexuosus against Staphylococcus aureus and Acinetobacter baumannii (2018)
Presentation / Conference Contribution

Staphylococcus aureus (S. aureus) and Acinetobacter baumannii (A. baumannii) are both significant
nosocomial pathogens that have become increasingly resistant to conventional antimicrobial
therapies. There is a need for alternative therapies to com... Read More about In vitro antimicrobial activity of Cymbopogon flexuosus against Staphylococcus aureus and Acinetobacter baumannii.

Interrogating water and public health concerns through participatory theatre methodologies - The Iheakpu-Awka example (2018)
Presentation / Conference Contribution

Health Humanities as an emerging discipline seeks the convergence of health and humanities in the effort to promote good health as well tackle health concerns. Theatre has been identified as a powerful tool of change for preventive medicine. As an ef... Read More about Interrogating water and public health concerns through participatory theatre methodologies - The Iheakpu-Awka example.

The antimicrobial activity of various essential oils against gram-negative and gram-positive bacteria (2017)
Presentation / Conference Contribution

Aims

The aim of this study is to assess the in vitro antimicrobial activity of several essential oils against Gram-negative and Gram-positive bacteria.

Methods and results

Disc diffusion, microdilution, and disc volatilisation assays, are me... Read More about The antimicrobial activity of various essential oils against gram-negative and gram-positive bacteria.

An evaluation of faecal transport swabs using the swab elution method in accordance with approved standard CLSI M40-A2 (2017)
Presentation / Conference Contribution

Introduction
Efficient absorption, transportation and release of specimens from faecal transport swabs are characteristics that commercial swabs must possess to be compliant with the M40-A2 criteria. The aim of this study was to evaluate and compare... Read More about An evaluation of faecal transport swabs using the swab elution method in accordance with approved standard CLSI M40-A2.

Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral (2016)
Journal Article

© 2016, The Author(s). The aim of this study was to determine the antimicrobial effects of lemongrass essential oil (C. flexuosus) and to determine cytotoxic effects of both test compounds on human dermal fibroblasts. Antimicrobial susceptibility scr... Read More about Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral.

Using the new CLSI M40-A2 Standard Coupled with Molecular Criteria to assess the performance of Sigma Transwab ® with Liquid Amies medium (2016)
Presentation / Conference Contribution

Abstract: Background: Sigma-Transwab® is a liquid medium format transport swab designed for use on automated processing platforms. The PurFlock® swab is intended to improve absorption and release of the specimen. In 2014 the revised standard CLSI M40... Read More about Using the new CLSI M40-A2 Standard Coupled with Molecular Criteria to assess the performance of Sigma Transwab ® with Liquid Amies medium.

Evaluation of the device Sigma Transwab® with special drawing pad foam polyurethane for collection and handling of samples using the swab elution and roll plate based on the new CLSI M40-A2 guidelines (2015)
Presentation / Conference Contribution

P167
Technology Assessment
VALUTAZIONE DEI DISPOSITIVI SIGMA TRANSWAB® DI RACCOLTA E TRASPORTO CAMPIONI CON SPECIALE TAMPONE DI PRELIEVO IN SCHIUMA POLIURETANO E TERRENO LIQUIDO UTILIZZANDO METODICA DI ELUIZIONE E ROLL PLATE SECONDO LINEE GUIDA CLS... Read More about Evaluation of the device Sigma Transwab® with special drawing pad foam polyurethane for collection and handling of samples using the swab elution and roll plate based on the new CLSI M40-A2 guidelines.

Antimicrobial susceptibility and time-kill analysis of single and combined essential oil blends against clinical and non-clinical isolates of bacteria and fungi (2014)
Presentation / Conference Contribution

The continued emergence of antibiotic resistant bacteria and infection outbreaks in healthcare and community settings has created a need for development of new antibiotics and exploration of alternative therapeutics. Essential oils (EOs) have been id... Read More about Antimicrobial susceptibility and time-kill analysis of single and combined essential oil blends against clinical and non-clinical isolates of bacteria and fungi.

A comparison of the sensitivity of four Staphylococcus aureus isolates to two chlorine-based disinfectants and an eco-friendly commercially available cleaning agent (2014)
Journal Article

© 2014 Taylor & Francis. The aim of this study was to determine the effect of household bleach, a sodium dichloroisocyanurate (NaDCC)-based disinfectant and an eco-friendly cleaning agent (EFCA) on four Staphylococcus aureus strains, including two... Read More about A comparison of the sensitivity of four Staphylococcus aureus isolates to two chlorine-based disinfectants and an eco-friendly commercially available cleaning agent.

The anti-biofilm activity of lemongrass (Cymbopogon flexuosus) and grapefruit (Citrus paradisi) essential oils against five strains of Staphylococcus aureus (2012)
Journal Article

Aims: To determine the sensitivity of five strains of Staphylococcus aureus to five essential oils (EOs) and to investigate the anti-biofilm activity of lemongrass and grapefruit EOs. Methods and Results: Antimicrobial susceptibility screening was ca... Read More about The anti-biofilm activity of lemongrass (Cymbopogon flexuosus) and grapefruit (Citrus paradisi) essential oils against five strains of Staphylococcus aureus.