Skip to main content

Research Repository

Advanced Search

All Outputs (464)

A screen-printed, amperometric, biosensor array for the detection of organophosphate pesticides based on inhibition of wild type, and mutant acetylcholinesterases, from Drosophila melanogaster (2004)
Journal Article
Hart, J. P., Crew, A. P., Hart, J. P., Wedge, R., Marty, J. L., & Fournier, D. (2004). A screen-printed, amperometric, biosensor array for the detection of organophosphate pesticides based on inhibition of wild type, and mutant acetylcholinesterases, from Drosophila melanogaster. Analytical Letters, 37(8), 1601-1610. https://doi.org/10.1081/AL-120037590

Screen-printed carbon electrodes (SPCEs) modified with cobalt phthalocyanine (CoPC) have been used as base transducers in the construction of amperometric pesticide biosensors. Six individual biosensors were fabricated by depositing wildtype (WT) ace... Read More about A screen-printed, amperometric, biosensor array for the detection of organophosphate pesticides based on inhibition of wild type, and mutant acetylcholinesterases, from Drosophila melanogaster.

Activation marker expression and apoptotic susceptibility of T-cell clones derived from CD34+, young and SENIEUR donors (2004)
Journal Article
McLeod, J. D., Pawelec, G., Bárcia, R. N., & Della Valle, N. S. (2004). Activation marker expression and apoptotic susceptibility of T-cell clones derived from CD34+, young and SENIEUR donors. Experimental Gerontology, 39(4), 531-538. https://doi.org/10.1016/j.exger.2003.11.015

T-cell clones (TCC) derived from human peripheral blood lymphocytes of a young control, a healthy elderly (SENIEUR) donor, or from CD34+ hematopoietic progenitor cells were utilised in this study to examine how in vivo and in vitro ageing affects T-c... Read More about Activation marker expression and apoptotic susceptibility of T-cell clones derived from CD34+, young and SENIEUR donors.

Using genetic programming for feature creation with a genetic algorithm feature selector (2004)
Journal Article
Smith, M. G., & Bull, L. (2004). Using genetic programming for feature creation with a genetic algorithm feature selector. Lecture Notes in Artificial Intelligence, 3242, 1163-1171. https://doi.org/10.1007/978-3-540-30217-9_117

The use of machine learning techniques to automatically analyse data for information is becoming increasingly widespread. In this paper we primarily examine the use of Genetic Programming and a Genetic Algorithm to preprocess data before it is classi... Read More about Using genetic programming for feature creation with a genetic algorithm feature selector.

Sequential and continuum bifurcations in degenerate elliptic equations (2004)
Journal Article
Beardmore, R. E., & Laister, R. (2004). Sequential and continuum bifurcations in degenerate elliptic equations. Proceedings of the American Mathematical Society, 132(01), 165-174. https://doi.org/10.1090/S0002-9939-03-06979-X

We examine the bifurcations to positive and sign-changing solutions of degenerate elliptic equations. In the problems we study, which do not represent Fredholm operators, we show that there is a critical parameter value at which an infinity of bifurc... Read More about Sequential and continuum bifurcations in degenerate elliptic equations.

'The very pests of society': The Irish and 150 years of public health in England (2004)
Journal Article
Scally, G. (2004). 'The very pests of society': The Irish and 150 years of public health in England. Clinical Medicine, 4(1), 77-81. https://doi.org/10.7861/clinmedicine.4-1-77

In the context of efforts to reduce health inequalities, the health status of the Irish in England should be a major subject for concern. As England's longest standing and most numerous ethnic minority, the Irish have at times been regarded as a publ... Read More about 'The very pests of society': The Irish and 150 years of public health in England.

Violations of expected utility theory in route-choice stated preferences: Certainty effect and inflation of small probabilities (2004)
Journal Article
Prashker, J. N., & Avineri, E. (2004). Violations of expected utility theory in route-choice stated preferences: Certainty effect and inflation of small probabilities. Transportation Research Record, 1894(1894), 222-229. https://doi.org/10.3141/1894-23

Common travel-choice models are based on the maximum utility assumption. However, the use of expected utility theory in descriptive models of individual choice has been criticized by behavioral scientists and recently also by transportation researche... Read More about Violations of expected utility theory in route-choice stated preferences: Certainty effect and inflation of small probabilities.

Temporary work agencies: Here today, gone tomorrow? (2004)
Journal Article
Purcell, J., Purcell, K., & Tailby, S. (2004). Temporary work agencies: Here today, gone tomorrow?. British Journal of Industrial Relations, 42(4), 705-725. https://doi.org/10.1111/j.1467-8543.2004.00337.x

The complexities of the triangular relationship between employer, worker and agency are explored in two sectors to establish the extent to which the use of agency workers constitutes strategic and rational decisions on the part of employers. Evidence... Read More about Temporary work agencies: Here today, gone tomorrow?.

Development of an electrochemical assay for 2,6-dinitrotoluene, based on a screen-printed carbon electrode, and its potential application in bioanalysis, occupational and public health (2003)
Journal Article
Ratcliffe, N. M., Hawkins, S. J., Pritchard, P. R., Hart, J. P., & Honeychurch, K. C. (2003). Development of an electrochemical assay for 2,6-dinitrotoluene, based on a screen-printed carbon electrode, and its potential application in bioanalysis, occupational and public health. Biosensors and Bioelectronics, 19(4), 305-312. https://doi.org/10.1016/S0956-5663%2803%2900208-2

Screen-printed carbon electrodes (SPCEs) have been successfully exploited as disposable sensors for the measurement of 2,6-dinitrotoluene (2,6-DNT) using a stripping voltammetric method. Initial investigations were undertaken using cyclic voltammetry... Read More about Development of an electrochemical assay for 2,6-dinitrotoluene, based on a screen-printed carbon electrode, and its potential application in bioanalysis, occupational and public health.

Bridging the gap between business models and system models (2003)
Journal Article
Kamm, R., & Odeh, M. (2003). Bridging the gap between business models and system models. Information and Software Technology, 45(15), 1053-1060. https://doi.org/10.1016/S0950-5849%2803%2900133-2

This paper discusses links that may be made between process models and Unified Modelling Language (UML) software specification techniques, working from an argument that the whole complexity of organisational activity cannot be captured by UML alone.... Read More about Bridging the gap between business models and system models.

Have cholinergic therapies reached their clinical boundary in Alzheimer's disease? (2003)
Journal Article
Jones, R. W. (2003). Have cholinergic therapies reached their clinical boundary in Alzheimer's disease?. International Journal of Geriatric Psychiatry, 18(SUPPL. 1), S7-S13. https://doi.org/10.1002/gps.936

The cholinergic hypothesis suggests that Alzheimer's disease (AD) results from a selective loss in cholinergic neurons with decreased acetylcholine levels. Treatments that increase the level of acetylcholine would be expected to provide clinical bene... Read More about Have cholinergic therapies reached their clinical boundary in Alzheimer's disease?.

The practical application of an artist's colour model as an alternative to CMYK (2003)
Journal Article
Parraman, C., & Hoskins, S. (2003). The practical application of an artist's colour model as an alternative to CMYK. Proceedings of SPIE, 5008, 129-137. https://doi.org/10.1117/12.475433

This paper presents an alternative view of colour, from the artist's perspective. It highlights problems that are current in inkjet and wideformat printing. And how other print processes, such as (silk)screenprint, can offer answers to developing ink... Read More about The practical application of an artist's colour model as an alternative to CMYK.

Rapid electrochemical detection and identification of catalase positive micro-organisms (2003)
Journal Article
Sippy, N., Luxton, R. W., Lewis, R., & Cowell, D. C. (2003). Rapid electrochemical detection and identification of catalase positive micro-organisms. Biosensors and Bioelectronics, 18(5-6), 741-749. https://doi.org/10.1016/S0956-5663%2803%2900023-X

The rapid detection and identification of bacteria has application in a number of fields, e.g. the food industry, environmental monitoring and biomedicine. While in biomedicine the number of organisms present during infection is multiples of millions... Read More about Rapid electrochemical detection and identification of catalase positive micro-organisms.

Human mitochondrial branched chain aminotransferase: Structural basis for substrate specificity and role of redox active cysteines (2003)
Journal Article
Yennawar, N., Conway, M. E., Wallin, R., Poole, L. B., & Hutson, S. M. (2003). Human mitochondrial branched chain aminotransferase: Structural basis for substrate specificity and role of redox active cysteines. BBA - Proteins and Proteomics, 1647(1-2), 61-65. https://doi.org/10.1016/S1570-9639%2803%2900051-7

Crystal structures of the fold type IV pyridoxal phosphate (PLP)-dependent human mitochondrial branched chain aminotransferase (hBCATm) reaction intermediates have provided a structural explanation for the kinetically determined substrate specificity... Read More about Human mitochondrial branched chain aminotransferase: Structural basis for substrate specificity and role of redox active cysteines.

Selecting plants to minimise radiocaesium in the food chain (2003)
Journal Article
Escobar-Gutiérrez, A. J., White, P. J., Swarup, K., Escobar-Gutierrez, A., Bowen, H. C., Willey, N., & Broadley, M. R. (2003). Selecting plants to minimise radiocaesium in the food chain. Plant and Soil, 249(1), 177-186. https://doi.org/10.1023/A%3A1022593307224

Caesium (Cs) is an alkali metal with chemical properties similar to potassium (K). It has no known role in plant nutrition and it is not toxic to plants at the micromolar concentrations occurring naturally in soil solutions. However, two radioisotope... Read More about Selecting plants to minimise radiocaesium in the food chain.

Feature construction and selection using genetic programming and a genetic algorithm (2003)
Journal Article
Smith, M. G., & Bull, L. (2003). Feature construction and selection using genetic programming and a genetic algorithm. Lecture Notes in Artificial Intelligence, 2610, 229-237. https://doi.org/10.1007/3-540-36599-0_21

The use of machine learning techniques to automatically analyse data for information is becoming increasingly widespread. In this paper we examine the use of Genetic Programming and a Genetic Algorithm to pre-process data before it is classified usin... Read More about Feature construction and selection using genetic programming and a genetic algorithm.

Cytochrome c, Glutathione, and the Possible Role of Redox Potentials in Apoptosis (2003)
Journal Article
Neill, S. J., Hancock, J. T., & Desikan, R. (2003). Cytochrome c, Glutathione, and the Possible Role of Redox Potentials in Apoptosis. Annals of the New York Academy of Sciences, 1010(Apopto), 446-448. https://doi.org/10.1196/annals.1299.081

The redox environment of the cell is now thought to be extremely important to control the activity of many proteins. During apoptosis, the intracellular redox potential (Eh) becomes more positive, with possible consequences for the mechanisms of apop... Read More about Cytochrome c, Glutathione, and the Possible Role of Redox Potentials in Apoptosis.

Exploring the Use of E-Shopping and Its Impact on Personal Travel Behavior in the Netherlands (2003)
Journal Article
Farag, S., Dijst, M., & Lanzendorf, M. (2003). Exploring the Use of E-Shopping and Its Impact on Personal Travel Behavior in the Netherlands. Transportation Research Record, 1858(1858), 47-54. https://doi.org/10.3141/1858-07

The Internet makes it possible to conduct activities such as working and shopping without traveling to activity places. As e-shopping becomes popular, it can fundamentally change travel behavior. The presented study uses a literature review, an Inter... Read More about Exploring the Use of E-Shopping and Its Impact on Personal Travel Behavior in the Netherlands.

Sensitivity to Uncertainty: Need for a Paradigm Shift (2003)
Journal Article
Prashker, J. N., & Avineri, E. (2003). Sensitivity to Uncertainty: Need for a Paradigm Shift. Transportation Research Record, 1854(1854), 90-98. https://doi.org/10.3141/1854-10

Existing common route choice models are based on random utility theory, which follows the maximum utility assumption. Recent intelligent transportation system applications have highlighted the need for better models of the behavioral processes involv... Read More about Sensitivity to Uncertainty: Need for a Paradigm Shift.

The investigation of chronic diarrhoea (2003)
Journal Article
Knight, C. J., & Sandhu, B. (2003). The investigation of chronic diarrhoea. Current Paediatrics, 13(2), 89-94. https://doi.org/10.1054/cupe.2002.0420

Chronic diarrhoea can present a major diagnostic and management problem, particularly in infants. It is an important cause of anxiety and frustration for the parents of affected children. In this article, we set out a logical approach to the investig... Read More about The investigation of chronic diarrhoea.