All Outputs (5)

Maleidride biosynthesis - construction of dimeric anhydrides - more than just heads or tails (2022)
Journal Article
Williams, K., Szwalbe, A. J., de Mattos-Shipley, K. M. J., Bailey, A. M., Cox, R. J., & Willis, C. L. (2022). Maleidride biosynthesis - construction of dimeric anhydrides - more than just heads or tails. Natural Product Reports, 40(1), 128-157. https://doi.org/10.1039/d2np00041e

Covering: up to early 2022 Maleidrides are a family of polyketide-based dimeric natural products isolated from fungi. Many maleidrides possess significant bioactivities, making them attractive pharmaceutical or agrochemical lead compounds. Their unus... Read More about Maleidride biosynthesis - construction of dimeric anhydrides - more than just heads or tails.

Cloning and expression of Burkholderia polyyne biosynthetic gene clusters in Paraburkholderia hosts provides a strategy for biopesticide development (2022)
Journal Article
Petrova, Y. D., Zhao, J., Webster, G., Mullins, A. J., Williams, K., Alswat, A. S., …Mahenthiralingam, E. (2022). Cloning and expression of Burkholderia polyyne biosynthetic gene clusters in Paraburkholderia hosts provides a strategy for biopesticide development. Microbial Biotechnology, 15(10), 2547-2561. https://doi.org/10.1111/1751-7915.14106

Burkholderia have potential as biocontrol agents because they encode diverse biosynthetic gene clusters (BGCs) for a range of antimicrobial metabolites. Given the opportunistic pathogenicity associated with Burkholderia species, heterologous BGC expr... Read More about Cloning and expression of Burkholderia polyyne biosynthetic gene clusters in Paraburkholderia hosts provides a strategy for biopesticide development.

COVID-19-related changes in outpatient CPAP setup pathways for OSA are linked with decreased 30-day CPAP usage (2022)
Journal Article
Turnbull, C. D., Allen, M., Appleby, J., Brown, R., Bryan, N., Cooper, A., …Nickol, A. (2022). COVID-19-related changes in outpatient CPAP setup pathways for OSA are linked with decreased 30-day CPAP usage. Thorax, 77(8), 839-841. https://doi.org/10.1136/thoraxjnl-2021-218635

The COVID-19 pandemic changed continuous positive airway pressure (CPAP) setup pathways. We evaluated patients commenced on CPAP in 2019 (prepandemic) and 2020 (post-first UK wave). Face-to-face (F2F) setup numbers, with CPAP turned on, decreased fro... Read More about COVID-19-related changes in outpatient CPAP setup pathways for OSA are linked with decreased 30-day CPAP usage.

In silico analyses of maleidride biosynthetic gene clusters (2022)
Journal Article
Williams, K., de Mattos-Shipley, K. M., Willis, C. L., & Bailey, A. M. (2022). In silico analyses of maleidride biosynthetic gene clusters. Fungal Biology and Biotechnology, 9(1), Article 2. https://doi.org/10.1186/s40694-022-00132-z

Maleidrides are a family of structurally related fungal natural products, many of which possess diverse, potent bioactivities. Previous identification of several maleidride biosynthetic gene clusters, and subsequent experimental work, has determined... Read More about In silico analyses of maleidride biosynthetic gene clusters.

Radioactivity in future phosphogypsum: New predictions based on estimates of ‘Peak P’ and rock phosphate resources (2022)
Journal Article
Willey, N., & Timbs, P. (2022). Radioactivity in future phosphogypsum: New predictions based on estimates of ‘Peak P’ and rock phosphate resources. Journal of Environmental Radioactivity, 244-245, Article 106828. https://doi.org/10.1016/j.jenvrad.2022.106828

Global food supplies currently depend on producing inorganic P fertilisers from a finite reserve of rock phosphate (RP). P fertilisers are themselves significant pollutants but their production from RP also leaves a phosphogypsum (PG) by-product that... Read More about Radioactivity in future phosphogypsum: New predictions based on estimates of ‘Peak P’ and rock phosphate resources.