Skip to main content

Research Repository

Advanced Search

All Outputs (86)

Volatilome of chill-stored European Seabass (Dicentrarchus labrax) fillets and Atlantic Salmon (Salmo salar) slices under modified atmosphere packaging (2020)
Journal Article
Kritikos, A., Aska, I., Ekonomou, S., Mallouchos, A., Parlapani, F. F., Haroutounian, S. A., & Boziaris, I. S. (2020). Volatilome of chill-stored European Seabass (Dicentrarchus labrax) fillets and Atlantic Salmon (Salmo salar) slices under modified atmosphere packaging. Molecules, 25(8), 1981. https://doi.org/10.3390/molecules25081981

Fish spoilage occurs due to production of metabolites during storage, from bacterial action and chemical reactions, which leads to sensory rejection. Investigating the volatilome profile can reveal the potential spoilage markers. The evolution of vol... Read More about Volatilome of chill-stored European Seabass (Dicentrarchus labrax) fillets and Atlantic Salmon (Salmo salar) slices under modified atmosphere packaging.

CHIELD: The causal hypotheses in evolutionary linguistics database (2020)
Journal Article
Roberts, S. G., Killin, A., Deb, A., Sheard, C., Greenhill, S. J., Sinnemäki, K., …Jordan, F. (2020). CHIELD: The causal hypotheses in evolutionary linguistics database. Journal of Language Evolution, 5(2), 101-120. https://doi.org/10.1093/jole/lzaa001

Language is one of the most complex of human traits. There are many hypotheses about how it originated, what factors shaped its diversity, and what ongoing processes drive how it changes. We present the Causal Hypotheses in Evolutionary Linguistics D... Read More about CHIELD: The causal hypotheses in evolutionary linguistics database.

Screen-printed carbon based biosensors and their applications in agri-food safety (2020)
Journal Article
Smart, A., Crew, A., Pemberton, R., Hughes, G., Doran, O., & Hart, J. P. (2020). Screen-printed carbon based biosensors and their applications in agri-food safety. Trends in Analytical Chemistry, 127, Article 115898. https://doi.org/10.1016/j.trac.2020.115898

This review focuses on the ways in which screen-printed carbon electrodes have been tailored with different biorecognition elements, including enzymes, antibodies, and aptamers, often with other modifiers, such as mediators and nanoparticles, to prod... Read More about Screen-printed carbon based biosensors and their applications in agri-food safety.

Impact of thermal and high-pressure treatments on the microbiological quality and in vitro digestibility of black soldier fly (Hermetia illucens) larvae (2020)
Journal Article
Campbell, M., Ortuño, J., Stratakos, A. C., Linton, M., Corcionivoschi, N., Elliott, T., …Theodoridou, K. (2020). Impact of thermal and high-pressure treatments on the microbiological quality and in vitro digestibility of black soldier fly (Hermetia illucens) larvae. Animals, 10(4), Article 682. https://doi.org/10.3390/ani10040682

Black soldier fly larvae (BSFL) are gaining importance in animal feeding due to their ability to upcycle low-value agroindustry by-products into high-protein biomass. The present study evaluated the nutritional composition of BSFL reared on brewer’s... Read More about Impact of thermal and high-pressure treatments on the microbiological quality and in vitro digestibility of black soldier fly (Hermetia illucens) larvae.

A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons (2020)
Journal Article
Stathakos, P., Jiménez-Moreno, N., Crompton, L. A., Nistor, P. A., Badger, J. L., Barbuti, P. A., …Lane, J. D. (2021). A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons. Autophagy, 17(4), 855-871. https://doi.org/10.1080/15548627.2020.1739441

Macroautophagy/autophagy cytoplasmic quality control pathways are required during neural development and are critical for the maintenance of functional neuronal populations in the adult brain. Robust evidence now exists that declining neuronal autoph... Read More about A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons.

Polyphenols from brown seaweeds as a potential antimicrobial agent in animal feeds (2020)
Journal Article
Ford, L., Stratakos, A. C., Theodoridou, K., Dick, J. T., Sheldrake, G. N., Linton, M., …Walsh, P. J. (2020). Polyphenols from brown seaweeds as a potential antimicrobial agent in animal feeds. ACS Omega, 5(16), 9093-9103. https://doi.org/10.1021/acsomega.9b03687

Seaweeds offer a natural source of antimicrobials that may help curb antibiotic resistance in livestock. The antibacterial activity of phlorotannin extracts isolated from two brown seaweeds Ascophyllum nodosum and Fucus serratus was tested. The mecha... Read More about Polyphenols from brown seaweeds as a potential antimicrobial agent in animal feeds.

Extraction-free, direct determination of caffeine in microliter volumes of beverages by thermal desorption-gas chromatography mass spectrometry (2020)
Journal Article
Peng, X., Brown, M., Bowdler, P., & Honeychurch, K. C. (2020). Extraction-free, direct determination of caffeine in microliter volumes of beverages by thermal desorption-gas chromatography mass spectrometry. International Journal of Analytical Chemistry, 2020, 1-7. https://doi.org/10.1155/2020/5405184

An extraction-free method requiring microliter (μL) volumes has been developed for the determination of caffeine in beverages. Using a pyrolysis-gas chromatography mass spectrometry system, the conditions required for the direct thermal desorption-g... Read More about Extraction-free, direct determination of caffeine in microliter volumes of beverages by thermal desorption-gas chromatography mass spectrometry.

The impact of the “World's 25 Most Endangered Primates” list on scientific publications and media (2020)
Journal Article
Acerbi, A., Kerhoas, D., Webber, A. D., McCabe, G., Mittermeier, R. A., & Schwitzer, C. (2020). The impact of the “World's 25 Most Endangered Primates” list on scientific publications and media. Journal for Nature Conservation, 54, 125794. https://doi.org/10.1016/j.jnc.2020.125794

Assessing the impact of conservation campaigns is of critical importance to optimise the use of limited resources. Lists of threatened species are often employed as media outreach tools, but their usefulness is rarely tested. We investigated whether... Read More about The impact of the “World's 25 Most Endangered Primates” list on scientific publications and media.

A Wnt-BMP4 signaling axis induces MSX and NOTCH proteins and promotes growth suppression and differentiation in neuroblastoma (2020)
Journal Article
Szemes, M., Melegh, Z., Bellamy, J., Greenhough, A., Kollareddy, M., Catchpoole, D., & Malik, K. (2020). A Wnt-BMP4 signaling axis induces MSX and NOTCH proteins and promotes growth suppression and differentiation in neuroblastoma. Cells, 9(3), Article 783. https://doi.org/10.3390/cells9030783

The Wnt and bone morphogenetic protein (BMP) signaling pathways are known to be crucial in the development of neural crest lineages, including the sympathetic nervous system. Surprisingly, their role in paediatric neuroblastoma, the prototypic tumor... Read More about A Wnt-BMP4 signaling axis induces MSX and NOTCH proteins and promotes growth suppression and differentiation in neuroblastoma.

Cyclic voltammetric behaviour of 2,4-dinitrotoluene at a glassy carbon electrode (2020)
Journal Article
Honeychurch, K. (2020). Cyclic voltammetric behaviour of 2,4-dinitrotoluene at a glassy carbon electrode. Scholarly Community Encyclopedia, 2019,

This paper describes the development of a simple voltammetric method for the measurement of 2,4-dinitrotoluene (24DNT) at glassy carbon electrode (GCE). Initial investigations were undertaken using cyclic voltammetry to characterise the redox behavio... Read More about Cyclic voltammetric behaviour of 2,4-dinitrotoluene at a glassy carbon electrode.

BCL–3 promotes cyclooxygenase–2/prostaglandin E2 signalling in colorectal cancer (2020)
Journal Article
Collard, T. J., Fallatah, H. M., Greenhough, A., Paraskeva, C., & Williams, A. C. (2020). BCL–3 promotes cyclooxygenase–2/prostaglandin E2 signalling in colorectal cancer. International Journal of Oncology, 56(5), 1304-1313. https://doi.org/10.3892/ijo.2020.5013

First discovered as an oncogene in leukaemia, recent reports highlight an emerging role for the proto-oncogene BCL-3 in solid tumours. Importantly, BCL-3 expression is upregulated in >30% of colorectal cancer cases and is reported to be associated wi... Read More about BCL–3 promotes cyclooxygenase–2/prostaglandin E2 signalling in colorectal cancer.

Taxonomy of prokaryotic viruses: 2018-2019 update from the ICTV Bacterial and Archaeal Viruses Subcommittee (2020)
Journal Article
Adriaenssens, E. M., Sullivan, M. B., Knezevic, P., van Zyl, L. J., Sarkar, B. L., Dutilh, B. E., …Krupovic, M. (2020). Taxonomy of prokaryotic viruses: 2018-2019 update from the ICTV Bacterial and Archaeal Viruses Subcommittee. Archives of Virology, 165(5), 1253-1260. https://doi.org/10.1007/s00705-020-04577-8

This article is a summary of the activities of the ICTV’s Bacterial and Archaeal Viruses Subcommittee for the years 2018 and 2019. Highlights include the creation of a new order, 10 families, 22 subfamilies, 424 genera and 964 species. Some of our co... Read More about Taxonomy of prokaryotic viruses: 2018-2019 update from the ICTV Bacterial and Archaeal Viruses Subcommittee.

Development of a facile fluorophosphonate-functionalised titanium surface for potential orthopaedic applications (2020)
Journal Article
Shiel, A. I., Ayre, W. N., Blom, A. W., Hallam, K. R., Heard, P. J., Payton, O., …Mansell, J. P. (2020). Development of a facile fluorophosphonate-functionalised titanium surface for potential orthopaedic applications. Journal of Orthopaedic Translation, 23, 140-151. https://doi.org/10.1016/j.jot.2020.02.002

Background: Aseptic loosening of total joint replacements (TJRs) continues to be the main cause of implant failures. The socioeconomic impact of surgical revisions is hugely significant; in the United Kingdom alone, it is estimated that £137 m is spe... Read More about Development of a facile fluorophosphonate-functionalised titanium surface for potential orthopaedic applications.

Contrasting sensitivity of nestling and fledgling Barn Swallow Hirundo rustica body mass to local weather conditions (2020)
Journal Article
Facey, R. J., Vafidis, J. O., Smith, J. A., Vaughan, I. P., & Thomas, R. J. (2020). Contrasting sensitivity of nestling and fledgling Barn Swallow Hirundo rustica body mass to local weather conditions. Ibis, 62(4), 1163-1174. https://doi.org/10.1111/ibi.12824

Local weather can influence the growth and development of young birds either indirectly, by modifying prey availability, or directly, by affecting energetic trade-offs. Such effects can have lasting implications for life history traits, but the natur... Read More about Contrasting sensitivity of nestling and fledgling Barn Swallow Hirundo rustica body mass to local weather conditions.

Pseudomonas kirkiae sp. nov., a novel species isolated from oak in the United Kingdom, and phylogenetic considerations of the genera Pseudomonas, Azotobacter and Azomonas (2020)
Journal Article
Bueno-Gonzalez, V., Brady, C., Denman, S., Allainguillaume, J., & Arnold, D. (2020). Pseudomonas kirkiae sp. nov., a novel species isolated from oak in the United Kingdom, and phylogenetic considerations of the genera Pseudomonas, Azotobacter and Azomonas. International Journal of Systematic and Evolutionary Microbiology, 70(4), 2426-2434. https://doi.org/10.1099/ijsem.0.004055

As the current episode of Acute Oak Decline (AOD) continues to affect native British oak in the United Kingdom, ongoing isola-tions from symptomatic and healthy oak have yielded a large Pseudomonas species population. These strains could be divided i... Read More about Pseudomonas kirkiae sp. nov., a novel species isolated from oak in the United Kingdom, and phylogenetic considerations of the genera Pseudomonas, Azotobacter and Azomonas.

Visualizing the invisible: Performing chaos theory (2020)
Journal Article
Weitkamp, E. (2021). Visualizing the invisible: Performing chaos theory. Leonardo, 54(3), 289-293. https://doi.org/10.1162/leon_a_01887

Edward Lorenz, a pioneering figure in the field of chaos theory, coined the phrase “butterfly effect” and posed the well-known question “Does the flap of a butterfly’s wings in Brazil set off a tornado in Texas?” In posing the question, Lorenz sought... Read More about Visualizing the invisible: Performing chaos theory.

BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease (2020)
Journal Article
Harris, M., El Hindy, M., Usmari-Moraes, M., Hudd, F., Shafei, M., Dong, M., …Conway, M. E. (in press). BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease. Free Radical Biology and Medicine, https://doi.org/10.1016/j.freeradbiomed.2020.01.019

Leucine, nutrient signal and substrate for the branched chain aminotransferase (BCAT) activates the mechanistic target of rapamycin (mTORC1) and regulates autophagic flux, mechanisms implicated in the pathogenesis of neurodegenerative conditions such... Read More about BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease.

ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia? (2020)
Journal Article
Vahabi, B., Jabr, R., Fry, C., McCloskey, K., Everaert, K., Agudelo, C. W., …Weiss, J. P. (2020). ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia?. Neurourology and Urodynamics, 39(S3 Supplement: ICI‐RS 2019), S88-S95. https://doi.org/10.1002/nau.24274

Introduction: The following is a report on the proceedings of the 2019 International Consultation on Incontinence-Research Society nocturia think tank (NTT). Objectives: The objectives of the 2019 NTT were as follows: (a) to evaluate the role of urot... Read More about ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia?.