All Outputs (19)

Carbon nanotube (CNT)-based biosensors (2021)
Journal Article
Ferrier, D., & Honeychurch, K. C. (2021). Carbon nanotube (CNT)-based biosensors. Biosensors, 11(12), Article 486. https://doi.org/10.3390/bios11120486

This review focuses on recent advances in the application of carbon nanotubes (CNTs) for the development of sensors and biosensors. The paper discusses various configurations of these devices, including their integration in analytical devices. Carbon... Read More about Carbon nanotube (CNT)-based biosensors.

Hyphenated mass spectrometry versus real‐time mass spectrometry techniques for the detection of volatile compounds from the human body (2021)
Journal Article
Gould, O., Drabińska, N., Ratcliffe, N., & de Lacy Costello, B. (2021). Hyphenated mass spectrometry versus real‐time mass spectrometry techniques for the detection of volatile compounds from the human body. Molecules, 26(23), Article 7185. https://doi.org/10.3390/molecules26237185

Mass spectrometry (MS) is an analytical technique that can be used for various applications in a number of scientific areas including environmental, security, forensic science, space exploration, agri‐food, and numerous others. MS is also continuing... Read More about Hyphenated mass spectrometry versus real‐time mass spectrometry techniques for the detection of volatile compounds from the human body.

Molecular hydrogen as medicine: An assessment of administration methods (2021)
Journal Article
Russell, G., Nenov, A., Kisher, H., & Hancock, J. T. (2021). Molecular hydrogen as medicine: An assessment of administration methods. Hydrogen, 2(4), 444-460. https://doi.org/10.3390/hydrogen2040025

Since the late 18th century, molecular hydrogen (H2) has been shown to be well tolerated, firstly in animals, and then in humans. However, although research into the beneficial effects of molecular hydrogen in both plant and mammalian physiology is g... Read More about Molecular hydrogen as medicine: An assessment of administration methods.

MicroRNAs and the DNA damage response: How is cell fate determined? (2021)
Journal Article
Visser, H., & Thomas, A. D. (2021). MicroRNAs and the DNA damage response: How is cell fate determined?. DNA Repair, 108, Article 103245. https://doi.org/10.1016/j.dnarep.2021.103245

It is becoming clear that the DNA damage response orchestrates an appropriate response to a given level of DNA damage, whether that is cell cycle arrest and repair, senescence or apoptosis. It is plausible that the alternative regulation of the DNA d... Read More about MicroRNAs and the DNA damage response: How is cell fate determined?.

Molecular hydrogen: Is this a viable new treatment for plants in the UK? (2021)
Journal Article
Hancock, J. T., LeBaron, T. W., May, J., Thomas, A., & Russell, G. (2021). Molecular hydrogen: Is this a viable new treatment for plants in the UK?. Plants, 10(11), Article 2270

Despite being trialed in other regions of the world, the use of molecular hydrogen (H2) for enhanced plant growth and postharvest storage of crops has yet to be widely accepted in the UK. The evidence continues to grow that treatment of plants and pl... Read More about Molecular hydrogen: Is this a viable new treatment for plants in the UK?.

Molecular hydrogen in agriculture (2021)
Journal Article
Zulfiqar, F., Russell, G., & Hancock, J. T. (2021). Molecular hydrogen in agriculture. Planta, 254(3), Article 56. https://doi.org/10.1007/s00425-021-03706-0

Main conclusion: H2 gas, usually in the form of H2-saturated water, could play a useful role in improving many aspects of plant growth and productivity, including resistance to stress tolerance and improved post-harvest durability. Therefore, molecul... Read More about Molecular hydrogen in agriculture.

Amino acid metabolism as a therapeutic target in cancer: A review (2021)
Journal Article
Endicott, M., Jones, M., & Hull, J. (2021). Amino acid metabolism as a therapeutic target in cancer: A review. Amino Acids, 53, 1169–1179. https://doi.org/10.1007/s00726-021-03052-1

Malignant cells often demonstrate a proliferative advantage when compared to non-malignant cells. However, the rapid growth and metabolism required for survival can also highlight vulnerabilities specific to these malignant cells. One such vulnerabil... Read More about Amino acid metabolism as a therapeutic target in cancer: A review.

Clean label alternatives in meat products (2021)
Journal Article
Delgado-Pando, G., Ekonomou, S. I., Stratakos, A. C., & Pintado, T. (2021). Clean label alternatives in meat products. Foods, 10(7), 1615. https://doi.org/10.3390/foods10071615

Food authorities have not yet provided a definition for the term “clean label”. However, food producers and consumers frequently use this terminology for food products with few and recognisable ingredients. The meat industry faces important challenge... Read More about Clean label alternatives in meat products.

Oxygen is instrumental for biological signalling: An overview (2021)
Journal Article
Hancock, J. (2021). Oxygen is instrumental for biological signalling: An overview. Oxygen, 1(1), 3-15. https://doi.org/10.3390/oxygen1010002

Control of cellular function is extremely complex, being reliant on a wide range of components. Several of these are small oxygen-based molecules. Although reactive compounds containing oxygen are usually harmful to cells when accumulated to relative... Read More about Oxygen is instrumental for biological signalling: An overview.

Molecular hydrogen: Redox reactions and possible biological interactions (2021)
Journal Article
Hancock, J. T., LeBaron, T. W., & Russell, G. (2021). Molecular hydrogen: Redox reactions and possible biological interactions. Reactive Oxygen Species, 11, m17–m25. https://doi.org/10.20455/ros.2021.m.803

Molecular hydrogen (H2), either as a gas or as hydrogen-rich water (HRW), is suggested to be a useful treatment for a range of human diseases and also to improve agricultural output. It is often posited that H2 accomplishes its biological action, in... Read More about Molecular hydrogen: Redox reactions and possible biological interactions.

Oxy-hydrogen gas: The rationale behind its use as a novel and sustainable treatment for COVID-19 and other respiratory diseases (2021)
Journal Article
Russell, G., Nenov, A., & Hancock, J. (2021). Oxy-hydrogen gas: The rationale behind its use as a novel and sustainable treatment for COVID-19 and other respiratory diseases. European Medical Journal, May 2021, https://doi.org/10.33590/emj/21-00027

Oxy-hydrogen gas (HHO) is a gaseous mixture of molecular hydrogen (H2) and molecular oxygen (O2) that is generated by the electrolysis of water and delivered in a 2:1 ratio (66% and 33%, respectively) through the use of non-invasive inhalation device... Read More about Oxy-hydrogen gas: The rationale behind its use as a novel and sustainable treatment for COVID-19 and other respiratory diseases.

A literature survey of all volatiles from healthy human breath and bodily fluids: The human volatilome (2021)
Journal Article
Drabińska, N., Flynn, C., Ratcliffe, N., Belluomo, I., Myridakis, A., Gould, O., …Costello, B. D. L. (2021). A literature survey of all volatiles from healthy human breath and bodily fluids: The human volatilome. Journal of Breath Research, 15(3), 034001. https://doi.org/10.1088/1752-7163/abf1d0

This paper comprises an updated version of the 2014 review which reported 1846 volatile organic compounds (VOCs) identified from healthy humans. In total over 900 additional VOCs have been reported since the 2014 review and the VOCs from semen have b... Read More about A literature survey of all volatiles from healthy human breath and bodily fluids: The human volatilome.

Recent progress in screen-printed electrochemical sensors and biosensors for the detection of estrogens (2021)
Journal Article
Musa, A. M., Kiely, J., Luxton, R., & Honeychurch, K. C. (2021). Recent progress in screen-printed electrochemical sensors and biosensors for the detection of estrogens. Trends in Analytical Chemistry, 139, Article 116254. https://doi.org/10.1016/j.trac.2021.116254

Estrogens have become increasingly prevalent in environmental samples across the world, posing a serious threat to human health. They have received considerable public attention due to their harmful effect on the normal endocrine functions of humans... Read More about Recent progress in screen-printed electrochemical sensors and biosensors for the detection of estrogens.

Interacting proteins, polymorphisms and the susceptibility of animals to SARS-CoV-2 (2021)
Journal Article
Hancock, J., Rouse, R., Stone, E., & Greenhough, A. (2021). Interacting proteins, polymorphisms and the susceptibility of animals to SARS-CoV-2. Animals, 11(3), Article 797. https://doi.org/10.3390/ani11030797

Abstract: COVID-19, caused by SARS-CoV-2, is a world-wide problem for the human population. It is known that some animal species, such as mink, can become infected and transmit the virus. However, the susceptibility of most animals is not known. Here... Read More about Interacting proteins, polymorphisms and the susceptibility of animals to SARS-CoV-2.

Epigenenetic regulation of alternative splicing: How lncRNAs tailor the message (2021)
Journal Article
Pisignano, G., & Ladomery, M. (2021). Epigenenetic regulation of alternative splicing: How lncRNAs tailor the message. Non-Coding RNA, 7(1), Article 21. https://doi.org/10.3390/ncrna7010021

Alternative splicing is a highly fine-tuned regulated process and one of the main drivers of proteomic diversity across eukaryotes. The vast majority of human multi-exon genes is alternatively spliced in a cell type-and tissue-specific manner, and de... Read More about Epigenenetic regulation of alternative splicing: How lncRNAs tailor the message.

The anti-cancer effect of Olea europaea L. products: A review (2021)
Journal Article
Antoniou, C., & Hull, J. (2021). The anti-cancer effect of Olea europaea L. products: A review. Current Nutrition Reports, 10, 99–124. https://doi.org/10.1007/s13668-021-00350-8

Purpose of Review: The olive tree (Olea europaea L.) has featured as a significant part of medicinal history, used to treat a variety of ailments within folk medicine. The Mediterranean diet, which is rich in olive products, is testament to Olea euro... Read More about The anti-cancer effect of Olea europaea L. products: A review.

Downstream signalling from molecular hydrogen (2021)
Journal Article
Hancock, J., & Russell, G. (2021). Downstream signalling from molecular hydrogen. Plants, 10(2), Article 367. https://doi.org/10.3390/plants10020367

Molecular hydrogen (H2) is now considered to be a part of the suite of small molecules which can control cellular activity. As such it has been suggested to be used in the therapy of diseases in humans but also to be used in plant science, to enhance... Read More about Downstream signalling from molecular hydrogen.

Training future generations to deliver evidence-based conservation and ecosystem management (2021)
Journal Article
Downey, H., Amano, T., Cadotte, M., Cook, C. N., Cooke, S. J., Haddaway, N. R., …Sutherland, W. J. (2021). Training future generations to deliver evidence-based conservation and ecosystem management. Ecological Solutions and Evidence, 2(1), Article e12032. https://doi.org/10.1002/2688-8319.12032

1. To be effective, the next generation of conservation practitioners and managers need to be critical thinkers with a deep understanding of how to make evidence‐based decisions and of the value of evidence synthesis. 2. If, as educators, we do no... Read More about Training future generations to deliver evidence-based conservation and ecosystem management.

Non-thermal methods for ensuring the microbiological quality and safety of seafood (2021)
Journal Article
Ekonomou, S. I., & Boziaris, I. S. (2023). Non-thermal methods for ensuring the microbiological quality and safety of seafood. Applied Sciences, 11(2), 833. https://doi.org/10.3390/app11020833

A literature search and systematic review were conducted to present and discuss the most recent research studies for the past twenty years on the application of non-thermal methods for ensuring the microbiological safety and quality of fish and seafo... Read More about Non-thermal methods for ensuring the microbiological quality and safety of seafood.