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All Outputs (70)

Effect of high-pressure processing on the shelf life, safety and organoleptic characteristics of lasagne ready meals during storage at refrigeration and abuse temperature (2015)
Journal Article
Stratakos, A. C., Linton, M., Patterson, M. F., & Koidis, A. (2015). Effect of high-pressure processing on the shelf life, safety and organoleptic characteristics of lasagne ready meals during storage at refrigeration and abuse temperature. Innovative Food Science and Emerging Technologies, 30, 1-7. https://doi.org/10.1016/j.ifset.2015.05.010

The effect of different pressure levels (500 and 600 MPa for 1 min at ambient temperature) on lasagne ready meal as a means of increasing the safety and shelf life during storage at refrigeration (4 °C) and abuse temperature (8 °C) was investigated.... Read More about Effect of high-pressure processing on the shelf life, safety and organoleptic characteristics of lasagne ready meals during storage at refrigeration and abuse temperature.

Between ambition and evidence (2015)
Journal Article
Weitkamp, E. (2015). Between ambition and evidence. Journal of Science Communication, 14(2),

Measuring impact may be challenging, but does that mean we should accept a lack of ambition? Researchers in all fields are grappling with the challenge of how to measure impact (in many different contexts, which naturally leads to many different appr... Read More about Between ambition and evidence.

BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling (2015)
Journal Article
Urban, B. C., Collard, T. J., Eagle, C. J., Southern, S. L., Greenhough, A., Hamdollah-Zadeh, M., …Williams, A. C. (2016). BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling. Gut, 65(7), 1151-1164. https://doi.org/10.1136/gutjnl-2014-308270

Objective Colorectal cancer remains the fourth most common cause of cancer-related mortality worldwide. Here we investigate the role of nuclear factor-?B (NF-?B) co-factor B-cell CLL/lymphoma 3 (BCL-3) in promoting colorectal tumour cell survival. De... Read More about BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling.

The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway (2015)
Journal Article
Abdelhamed, Z. A., Natarajan, S., Wheway, G., Inglehearn, C. F., Toomes, C., Johnson, C. A., & Jagger, D. J. (2015). The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway. Disease Models and Mechanisms, 8(6), 527-541. https://doi.org/10.1242/dmm.019083

© 2015. Published by The Company of Biologists Ltd. Ciliopathies are a group of developmental disorders that manifest with multi-organ anomalies. Mutations in TMEM67 (MKS3) cause a range of human ciliopathies, including Meckel-Gruber and Joubert synd... Read More about The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway.

Performance of charged aerosol detection with hydrophilic interaction chromatography (2015)
Journal Article
Russell, J. J., Heaton, J. C., Underwood, T., Boughtflower, R., & McCalley, D. V. (2015). Performance of charged aerosol detection with hydrophilic interaction chromatography. Journal of Chromatography A, 1405, 72-84. https://doi.org/10.1016/j.chroma.2015.05.050

© 2015 The Authors. The performance of the charged aerosol detector (CAD) was investigated using a diverse set of 29 solutes, including acids, bases and neutrals, over a range of mobile phase compositions, particularly with regard to its suitability... Read More about Performance of charged aerosol detection with hydrophilic interaction chromatography.

Differential responses to woodland character and landscape context by cryptic bats in urban environments (2015)
Journal Article
Lintott, P. R., Bunnefeld, N., Minderman, J., Fuentes-Montemayor, E., Mayhew, R. J., Olley, L., & Park, K. J. (2015). Differential responses to woodland character and landscape context by cryptic bats in urban environments. PLoS ONE, 10(5), Article e0126850. https://doi.org/10.1371/journal.pone.0126850

© 2015 Lintott et al. Urbanisation is one of the most dramatic forms of land use change which relatively few species can adapt to. Determining how and why species respond differently to urban habitats is important in predicting future biodiversity lo... Read More about Differential responses to woodland character and landscape context by cryptic bats in urban environments.

The impacts of new street light technologies: Experimentally testing the effects on bats of changing from low-pressure sodium to white metal halide (2015)
Journal Article
Stone, E. L., Wakefield, A., Harris, S., & Jones, G. (2015). The impacts of new street light technologies: Experimentally testing the effects on bats of changing from low-pressure sodium to white metal halide. Philosophical Transactions B: Biological Sciences, 370(1667), https://doi.org/10.1098/rstb.2014.0127

© 2015 The Authors. All rights reserved. Artificial light at night is a major feature of anthropogenic global change and is increasingly recognized as affecting biodiversity, often negatively. On a global scale, newer technology white lights are repl... Read More about The impacts of new street light technologies: Experimentally testing the effects on bats of changing from low-pressure sodium to white metal halide.

Development of a novel reagentless, screen-printed amperometric biosensor based on glutamate dehydrogenase and NAD+, integrated with multi-walled carbon nanotubes for the determination of glutamate in food and clinical applications (2015)
Journal Article
Hughes, G., Pemberton, R. M., Fielden, P. R., & Hart, J. P. (2015). Development of a novel reagentless, screen-printed amperometric biosensor based on glutamate dehydrogenase and NAD+, integrated with multi-walled carbon nanotubes for the determination of glutamate in food and clinical applications. Sensors and Actuators B: Chemical, 216, 614-621. https://doi.org/10.1016/j.snb.2015.04.066

© 2015 Elsevier B.V. Abstract A screen printed carbon electrode (SPCE) containing the electrocatalyst Meldola's Blue (MB) has been investigated as the base transducer for a reagentless glutamate biosensor. The biopolymer chitosan (CHIT) and multiwall... Read More about Development of a novel reagentless, screen-printed amperometric biosensor based on glutamate dehydrogenase and NAD+, integrated with multi-walled carbon nanotubes for the determination of glutamate in food and clinical applications.

Making the most of what we have: Application of extrapolation approaches in radioecological wildlife transfer models (2015)
Journal Article
Beresford, N. A., Wood, M. D., Vives i Batlle, J., Yankovich, T. L., Bradshaw, C., & Willey, N. (2016). Making the most of what we have: Application of extrapolation approaches in radioecological wildlife transfer models. Journal of Environmental Radioactivity, 151(2), 373-386. https://doi.org/10.1016/j.jenvrad.2015.03.022

© 2015 The Authors. We will never have data to populate all of the potential radioecological modelling parameters required for wildlife assessments. Therefore, we need robust extrapolation approaches which allow us to make best use of our available k... Read More about Making the most of what we have: Application of extrapolation approaches in radioecological wildlife transfer models.

High-resolution melt and morphological analyses of mealybugs (Hemiptera: Pseudococcidae) from cacao: Tools for the control of Cacao swollen shoot virus spread (2015)
Journal Article
Wetten, A., Campbell, C., & Allainguillaume, J. (2016). High-resolution melt and morphological analyses of mealybugs (Hemiptera: Pseudococcidae) from cacao: Tools for the control of Cacao swollen shoot virus spread. Pest Management Science, 72(3), 527-533. https://doi.org/10.1002/ps.4017

© 2015 Society of Chemical Industry. BACKGROUND: Mealybugs (Hemiptera: Coccoidea: Pseudococcidae) are key vectors of badnaviruses, including Cacao swollen shoot virus (CSSV), the most damaging virus affecting cacao (Theobroma cacao L.). The effective... Read More about High-resolution melt and morphological analyses of mealybugs (Hemiptera: Pseudococcidae) from cacao: Tools for the control of Cacao swollen shoot virus spread.

Moving forward, looking back (2015)
Journal Article
Weitkamp, E., & Rodari, P. (2015). Moving forward, looking back. Journal of Science Communication, 14(1),

This issue sees the implementation of new designs for the JCOM website and articles and there are plans for further updates over the next year. In a recent survey, we have explored readers opinions of the journal with a view to introducing improvemen... Read More about Moving forward, looking back.

YAP is essential for tissue tension to ensure vertebrate 3D body shape (2015)
Journal Article
Krens, S. F., Porazinski, S., Wang, H., Asaoka, Y., Behrndt, M., Miyamoto, T., …Furutani-Seiki, M. (2015). YAP is essential for tissue tension to ensure vertebrate 3D body shape. Nature, 521(7551), 217-221. https://doi.org/10.1038/nature14215

© 2015 Macmillan Publishers Limited. All rights reserved. Vertebrates have a unique 3D body shape in which correct tissue and organ shape and alignment are essential for function. For example, vision requires the lens to be centred in the eye cup whi... Read More about YAP is essential for tissue tension to ensure vertebrate 3D body shape.

Amperometric determination of hydrogen peroxide at a silver electrode fabricated from a recycled compact disc (2015)
Journal Article
Maynard, C., & Honeychurch, K. C. (2015). Amperometric determination of hydrogen peroxide at a silver electrode fabricated from a recycled compact disc. Advances in Analytical Chemistry, 5(2), 25-30. https://doi.org/10.5923/j.aac.20150502.01

This present study investigates the utilisation of Ag electrodes fabricated from recycled recordable compact discs (CD-R) for the amperometric determination of hydrogen peroxide. The analytical curve was linear up to at least 30 mM hydrogen peroxide... Read More about Amperometric determination of hydrogen peroxide at a silver electrode fabricated from a recycled compact disc.

A systematic review of the socio-ethical aspects of Massive Online Open Courses (2015)
Journal Article
Rolfe, V. (2015). A systematic review of the socio-ethical aspects of Massive Online Open Courses

Massive open online courses (MOOCs) offer learners across the globe unprecedented access to education. Through sophisticated e-learning technologies and web approaches, MOOCs attract massive scale participation and global interest. Some commercial ve... Read More about A systematic review of the socio-ethical aspects of Massive Online Open Courses.

A proposed new bacteriophage subfamily: “Jerseyvirinae” (2015)
Journal Article
Anany, H., Switt, A. I. M., De Lappe, N., Ackermann, H., Reynolds, D. M., Kropinski, A. M., …Turner, D. (2015). A proposed new bacteriophage subfamily: “Jerseyvirinae”. Archives of Virology, 160(4), 1021-1033. https://doi.org/10.1007/s00705-015-2344-z

© 2015, Springer-Verlag Wien. Based on morphology and comparative nucleotide and protein sequence analysis, a new subfamily of the family Siphoviridae is proposed, named “Jerseyvirinae” and consisting of three genera, “Jerseylikevirus”, “Sp3unalikevi... Read More about A proposed new bacteriophage subfamily: “Jerseyvirinae”.

Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: Implications for targeting cancer stem cells (2015)
Journal Article
Williams, A. C., Paraskeva, C., Greenhough, A., Lane, J. D., Collard, T. J., Jones, R. F., …Williams, A. C. (2015). Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: Implications for targeting cancer stem cells. British Journal of Cancer, 112(4), 714-719. https://doi.org/10.1038/bjc.2015.4

© 2015 Cancer Research UK. Background:LGR5 is an important marker of intestinal stem cells and performs its vital functions at the cell membrane. Despite the importance of LGR5 to both normal and cancer stem cell biology, it is not known how microenv... Read More about Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: Implications for targeting cancer stem cells.

Metabolism of androstenone, 17β-estradiol and dihydrotestosterone in primary cultured pig hepatocytes and the role of 3β-hydroxysteroid dehydrogenase in this process (2015)
Journal Article
Chen, G., Bai, Y., Ren, L., Zhu, D., Li, Y., Fang, M., …Doran, O. (2015). Metabolism of androstenone, 17β-estradiol and dihydrotestosterone in primary cultured pig hepatocytes and the role of 3β-hydroxysteroid dehydrogenase in this process. PLoS ONE, 10(1), Article e113194. https://doi.org/10.1371/journal.pone.0113194

© 2015 Chen et al. Steroids metabolism plays an important role in mammals and contributes to quality of pig meat. The main objective of this study was to identify metabolites of androstenone, 17β-estradiol and dihydrotestosterone using primary cultur... Read More about Metabolism of androstenone, 17β-estradiol and dihydrotestosterone in primary cultured pig hepatocytes and the role of 3β-hydroxysteroid dehydrogenase in this process.

A strategic approach for the visualisation of the low abundance protein fatty acid binding protein 7 (2015)
Journal Article
Dean, S. J., Perks, C. C., Rhodes, A., Holly, J. M., & Jarrett, C. (2015). A strategic approach for the visualisation of the low abundance protein fatty acid binding protein 7. American journal of biomedical sciences, 7(1), 15-25. https://doi.org/10.5099/aj150100015

Fatty acid binding protein 7 (FABP7) is a 15kDa protein that plays a role in fatty acid transport, solubilisation and metabolism. It has been found to be overexpressed in triple negative/basal like breast cancer patients. The role of FABP7 in these... Read More about A strategic approach for the visualisation of the low abundance protein fatty acid binding protein 7.