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Stable isotope switching (SIS): A new stable isotope probing (SIP) approach to determine carbon flow in the soil food web and dynamics in organic matter pools (2012)
Journal Article
Hornibrook, E. R., Maxfield, P. J., Dildar, N., Stott, A. W., & Evershed, R. P. (2012). Stable isotope switching (SIS): A new stable isotope probing (SIP) approach to determine carbon flow in the soil food web and dynamics in organic matter pools. Rapid Communications in Mass Spectrometry, 26(8), 997-1004. https://doi.org/10.1002/rcm.6172

RATIONALE Recent advances in stable isotope probing (SIP) have allowed direct linkage of microbial population structure and function. This paper details a new development of SIP, Stable Isotope Switching (SIS), which allows the simultaneous assessmen... Read More about Stable isotope switching (SIS): A new stable isotope probing (SIP) approach to determine carbon flow in the soil food web and dynamics in organic matter pools.

A comparison of overload behaviour for some sub 2μm totally porous and sub 3μm shell particle columns with ionised solutes (2012)
Journal Article
Buckenmaier, S. M. C., Fallas, M. M., & McCalley, D. V. (2012). A comparison of overload behaviour for some sub 2μm totally porous and sub 3μm shell particle columns with ionised solutes. Journal of Chromatography A, 1235, 49-59. https://doi.org/10.1016/j.chroma.2012.02.027

The overloading performance of some 2.7 μm shell and sub 2 μm totally porous columns, including one pair manufactured from similar materials with similar bonding chemistries, was compared using strongly acidic and basic probe compounds. In general, t... Read More about A comparison of overload behaviour for some sub 2μm totally porous and sub 3μm shell particle columns with ionised solutes.

Assessments and admissions during the first 6 years of a UK medium secure DSPD service (2012)
Journal Article
Freestone, M., Taylor, C., Milsom, S., Mikton, C., Ullrich, S., Phillips, O., & Coid, J. (2012). Assessments and admissions during the first 6 years of a UK medium secure DSPD service. Criminal Behaviour and Mental Health, 22(2), 91-107. https://doi.org/10.1002/cbm.1823

Background: Offenders with personality disorder represent a considerable burden on mental health and criminal justice services. Millfields Unit was one of the pilot medium secure units (MSUs) established by the UK Department of Health and Ministry of... Read More about Assessments and admissions during the first 6 years of a UK medium secure DSPD service.

Afghanistan's ethnic groups share a y-chromosomal heritage structured by historical events (2012)
Journal Article
Haber, M., Platt, D. E., Ashrafian Bonab, M., Youhanna, S. C., Soria-Hernanz, D. F., Martínez-Cruz, B., …The Genographic Consortium. (2012). Afghanistan's ethnic groups share a y-chromosomal heritage structured by historical events. PLoS ONE, 7(3), e34288. https://doi.org/10.1371/journal.pone.0034288

Afghanistan has held a strategic position throughout history. It has been inhabited since the Paleolithic and later became a crossroad for expanding civilizations and empires. Afghanistan's location, history, and diverse ethnic groups present a uniqu... Read More about Afghanistan's ethnic groups share a y-chromosomal heritage structured by historical events.

Screen-printed electrochemical sensors and biosensors for monitoring metal pollutants (2012)
Journal Article
Honeychurch, K. C. (2012). Screen-printed electrochemical sensors and biosensors for monitoring metal pollutants. https://doi.org/10.5640/insc.020101

The present review (with 231 references) focuses on developments made in the area of screen-printed biosensors and sensors for the determination of metal ions in industrial, environmental and biomedical applications. The year 2012 represents the twen... Read More about Screen-printed electrochemical sensors and biosensors for monitoring metal pollutants.

Muscle weakness, health status and frequency of exacerbations in chronic obstructive pulmonary disease (2012)
Journal Article
Ansari, K., Keaney, N., Taylor, I., Burns, G., & Farrow, M. (2012). Muscle weakness, health status and frequency of exacerbations in chronic obstructive pulmonary disease. Postgraduate Medical Journal, 88(1041), 372-376. https://doi.org/10.1136/postgradmedj-2011-130293

Background: Multiple factors contribute to muscle weakness and reduced muscle mass in chronic obstructive pulmonary disease (COPD) and this impacts patients' quality of life. One factor implicated in this process is systemic inflammation, an accompan... Read More about Muscle weakness, health status and frequency of exacerbations in chronic obstructive pulmonary disease.

N*-(carboxymethyl)lysine content of foods commonly consumed in a Western style diet (2012)
Journal Article
Cuskelly, G. J., Woodside, J. V., Hull, G. L. J., & Ames, J. (2012). N*-(carboxymethyl)lysine content of foods commonly consumed in a Western style diet. Food Chemistry, 131(1), 170-174. https://doi.org/10.1016/j.foodchem.2011.08.055

The potential adverse effects on health of diet-derived advanced glycation end-products (AGEs) is of current interest, due to their proposed involvement in the disease progression of diabetic and uraemic conditions. However, accurate information abou... Read More about N*-(carboxymethyl)lysine content of foods commonly consumed in a Western style diet.

Effect of mouth-rinse formulations on oral malodour processes in tongue-derived perfusion biofilm model (2012)
Journal Article
Saad, S., Hewett, K., & Greenman, J. (2012). Effect of mouth-rinse formulations on oral malodour processes in tongue-derived perfusion biofilm model. Journal of Breath Research, 6(1), https://doi.org/10.1088/1752-7155/6/1/016001

An in vitro matrix biofilm perfusion model of tongue-derived microcosms for studying volatile sulfur compound (VSC) biogenesis has been previously described. The model was modified in order to monitor H 2 S in situ by use of a specialized electrode a... Read More about Effect of mouth-rinse formulations on oral malodour processes in tongue-derived perfusion biofilm model.

A meckelin-filamin a interaction mediates ciliogenesis (2012)
Journal Article
Adams, M., Simms, R. J., Abdelhamed, Z., Dawe, H. R., Szymanska, K., Logan, C. V., …Johnson, C. A. (2012). A meckelin-filamin a interaction mediates ciliogenesis. Human Molecular Genetics, 21(6), 1272-1286. https://doi.org/10.1093/hmg/ddr557

MKS3, encoding the transmembrane receptor meckelin, is mutated in Meckel-Gruber syndrome (MKS), an autosomal-recessive ciliopathy. Meckelin localizes to the primary cilium, basal body and elsewhere within the cell. Here, we found that the cytoplasmic... Read More about A meckelin-filamin a interaction mediates ciliogenesis.

A Printed Electrocatalyst for Hydrogen Peroxide Reduction (2012)
Journal Article
Gonzalez-Macia, L., Smyth, M. R., & Killard, A. (2012). A Printed Electrocatalyst for Hydrogen Peroxide Reduction. Electroanalysis, 24(3), 609-614. https://doi.org/10.1002/elan.201100444

The modification of silver screen-printed electrodes with a dodecyl benzenesulfonic acid and KCl solution was performed by inkjet printing. Scanning Electron Microscopy was performed to characterize the electrode surfaces. Electrochemical reduction o... Read More about A Printed Electrocatalyst for Hydrogen Peroxide Reduction.

‘Younger People Have Like More of an Imagination, No Offence’: Participant Perspectives on Public Engagement (2012)
Journal Article
Wilkinson, C., Dawson, E., & Bultitude, K. (2012). ‘Younger People Have Like More of an Imagination, No Offence’: Participant Perspectives on Public Engagement. International Journal of Science Education, Part B: Communication and Public Engagement, 2(1), 43-61. https://doi.org/10.1080/21548455.2011.628503

© 2012, Copyright Taylor & Francis Group, LLC. A wide range of work has reported on the outcomes of public engagement activities and the views expressed by public participants towards specific areas of science and technology. Such work has rarely g... Read More about ‘Younger People Have Like More of an Imagination, No Offence’: Participant Perspectives on Public Engagement.

The critical scale of small-scale spatial variation in ecological patterns and processes in intertidal macrobenthic seagrass assemblages (2012)
Journal Article
Barnes, R. S., & Ellwood, M. D. F. (2012). The critical scale of small-scale spatial variation in ecological patterns and processes in intertidal macrobenthic seagrass assemblages. Estuarine, Coastal and Shelf Science, 98, 119-125. https://doi.org/10.1016/j.ecss.2011.12.014

Earlier work on benthic faunal assemblages in intertidal seagrass beds has shown maximal structural variation at spatial scales

An operative method to obtain sharp nonlinear stability for systems with spatially dependent coefficients (2012)
Journal Article
Hill, A. A., & Malashetty, M. S. (2012). An operative method to obtain sharp nonlinear stability for systems with spatially dependent coefficients. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 468(2138), 323-336. https://doi.org/10.1098/rspa.2011.0137

This paper explores an operative technique for deriving nonlinear stability by studying double-diffusive porous convection with a concentration-based internal heat source. Previous stability analyses on this problem have yielded regions of potential... Read More about An operative method to obtain sharp nonlinear stability for systems with spatially dependent coefficients.

Differential redox potential between the human cytosolic and mitochondrial branched-chain aminotransferase (2012)
Journal Article
Coles, S. J., Hancock, J. T., & Conway, M. E. (2012). Differential redox potential between the human cytosolic and mitochondrial branched-chain aminotransferase. Acta Biochimica et Biophysica Sinica, 44(2), 172-176. https://doi.org/10.1093/abbs/gmr103

The human branched-chain aminotransferase (hBCAT) isoenzymes are CXXC motif redox sensitive homodimers central to glutamate metabolism in the central nervous system. These proteins respond differently to oxidation by H 2O 2, NO, and S-glutathionylati... Read More about Differential redox potential between the human cytosolic and mitochondrial branched-chain aminotransferase.

Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways (2012)
Journal Article
Dallosso, A., Oster, B., Greenhough, A., Thorsen, K., Curry, T., Owen, C., …Malik, K. (2012). Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways. Oncogene, 31, 4409-4419

Loss of tumor suppressor gene function can occur as a result of epigenetic silencing of large chromosomal regions, referred to as long-range epigenetic silencing (LRES) and genome-wide analyses have revealed that LRES is present in many cancer types.... Read More about Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways.

Stability of double-diffusive convection induced by selective absorption of radiation in a fluid layer (2012)
Journal Article
Wicks, T. J., & Hill, A. A. (2012). Stability of double-diffusive convection induced by selective absorption of radiation in a fluid layer. Continuum Mechanics and Thermodynamics, 24(3), 229-237. https://doi.org/10.1007/s00161-012-0234-0

Linear and nonlinear stability analyses were performed on a fluid layer with a concentration-based internal heat source. Clear bimodal behaviour in the neutral curve (with stationary and oscillatory modes) is observed in the region of the onset of os... Read More about Stability of double-diffusive convection induced by selective absorption of radiation in a fluid layer.

MKS1 interacts with components of the ubiquitin-proteasome pathway to regulate ciliogenesis and multiple signalling pathways (2012)
Journal Article
Wheway, G., Abdelhamed, Z., Natarajan, S., & Johnson, C. A. (2012). MKS1 interacts with components of the ubiquitin-proteasome pathway to regulate ciliogenesis and multiple signalling pathways. Cilia, 1(S1), P108. https://doi.org/10.1186/2046-2530-1-S1-P108

MKS1, a ciliary protein containing a B9 domain of unknown function, plays an important role in ciliogenesis. Mutation of the MKS1 gene causes the neonatal lethal multi-organ developmental condition Meckel-Gruber syndrome, characterized by severe cili... Read More about MKS1 interacts with components of the ubiquitin-proteasome pathway to regulate ciliogenesis and multiple signalling pathways.

Engaging teenagers with genetics and genomics through a school-based competition: Pilot evaluation (2012)
Journal Article
Weitkamp, E., & Arnold, D. L. (2012). Engaging teenagers with genetics and genomics through a school-based competition: Pilot evaluation. International Journal of Science and Society, 4(1), 63-68

As part of a university outreach programme, the authors ran an interschool competition encouraging young people (year 10, age 14–15) to explore their ideas about the likely social impacts of whole genome screening. Schools participating in the comp... Read More about Engaging teenagers with genetics and genomics through a school-based competition: Pilot evaluation.

Comparison of cytotoxic changes in ECV304 cell through exposure to DMSO and sodium butyrate using impedance spectroscopy (2012)
Journal Article
Wang, Z., Kiely, J., Vargas, A. M., & Luxton, R. W. (2012). Comparison of cytotoxic changes in ECV304 cell through exposure to DMSO and sodium butyrate using impedance spectroscopy. Procedia Chemistry, 6, 89-99. https://doi.org/10.1016/j.proche.2012.10.134

This paper decides an impedance spectroscopy measurement system for real-time monitoring of cellular toxicity. The system is used to compare the impedance response of ECV304 cells to two toxicants, dimethyl sulphoxide (DMSO) and sodium butyrate. The... Read More about Comparison of cytotoxic changes in ECV304 cell through exposure to DMSO and sodium butyrate using impedance spectroscopy.