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Paramagnetic particle detection for use with an immunoassay based biosensor (2007)
Journal Article
Kiely, J., Hawkins, P., Wraith, P., & Luxton, R. (2007). Paramagnetic particle detection for use with an immunoassay based biosensor. IET Science Measurement and Technology, 1(5), 270-275. https://doi.org/10.1049/iet-smt%3A20060103

A biosensor and detection system that can provide measurement of analyte concentration within a test sample in four minutes is presented. The biosensor uses an immunoassay with micrometre-sized paramagnetic particle (PMP) labels for quantification. A... Read More about Paramagnetic particle detection for use with an immunoassay based biosensor.

Assessment of the relative toxicity of Cu2+ by measuring structural changes of supercoiled DNA (2007)
Journal Article
Pan, G., Chang, G., Chen, H., & Giusti, L. (2007). Assessment of the relative toxicity of Cu2+ by measuring structural changes of supercoiled DNA. Environmental Pollution, 148(2), 477-482. https://doi.org/10.1016/j.envpol.2006.12.005

A method for the measurement of the relative toxicity of Cu2+ in aquatic environments is proposed. It is based on the quantitative measurement on the shape change of the supercoiled DNA after it is contacted with different levels of Cu2+ for various... Read More about Assessment of the relative toxicity of Cu2+ by measuring structural changes of supercoiled DNA.

Development of a novel electrochemical immuno-assay using a screen printed electrode for the determination of secretory immunoglobulin A in human sweat (2007)
Journal Article
Cowell, D. C., Crew, A. P., Alford, C., & Hart, J. P. (2007). Development of a novel electrochemical immuno-assay using a screen printed electrode for the determination of secretory immunoglobulin A in human sweat. Electrochimica Acta, 52(16), 5232-5237. https://doi.org/10.1016/j.electacta.2007.02.035

This paper reports on the steps involved in the development of a novel electrochemical immunoassay for secretory immunoglobulin A (sIgA) determinations in human sweat. This novel immunoassay involves an initial step whereby sweat sIgA is adsorbed ont... Read More about Development of a novel electrochemical immuno-assay using a screen printed electrode for the determination of secretory immunoglobulin A in human sweat.

A novel branched-chain amino acid metabolon: Protein-protein interactions in a supramolecular complex (2007)
Journal Article
Islam, M. M., Wallin, R., Wynn, R. M., Conway, M., Fujii, H., Mobley, J. A., …Hutson, S. M. (2007). A novel branched-chain amino acid metabolon: Protein-protein interactions in a supramolecular complex. Journal of Biological Chemistry, 282(16), 11893-11903. https://doi.org/10.1074/jbc.M700198200

The catabolic pathways of branched-chain amino acids have two common steps. The first step is deamination catalyzed by the vitamin B6-dependent branched-chain aminotransferase isozymes (BCATs) to produce branched-chain α-keto acids (BCKAs). The secon... Read More about A novel branched-chain amino acid metabolon: Protein-protein interactions in a supramolecular complex.

Voltammetric behaviour of DNA bases at a screen-printed carbon electrode and its application to a simple and rapid voltammetric method for the determination of oxidative damage in double stranded DNA (2007)
Journal Article
O'Donovan, M. R., Honeychurch, K. C., & Hart, J. P. (2007). Voltammetric behaviour of DNA bases at a screen-printed carbon electrode and its application to a simple and rapid voltammetric method for the determination of oxidative damage in double stranded DNA. Biosensors and Bioelectronics, 22(9-10), 2057-2064. https://doi.org/10.1016/j.bios.2006.09.019

Screen-printed carbon electrodes (SPCEs) have been investigated as possible sensors to identify γ-irradiation induced oxidative damage in double stranded (ds) DNA. Studies were undertaken to explore the possibility of using both cyclic voltammetry an... Read More about Voltammetric behaviour of DNA bases at a screen-printed carbon electrode and its application to a simple and rapid voltammetric method for the determination of oxidative damage in double stranded DNA.

Nitric oxide, stomatal closure and abiotic stress (2007)
Journal Article
Neill, S., Barros, R. S., Bright, J., Desikan, R., Hancock, J. T., Harrison, J., …Ribeiro, D. M. (2007). Nitric oxide, stomatal closure and abiotic stress. Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, 146(4), S257. https://doi.org/10.1016/j.cbpa.2007.01.648

Various data indicate that nitric oxide (NO) is an endogenous signal in plants that mediates responses to several stimuli. Experimental evidence in support of such signalling roles for NO has been obtained via the application of NO (usually in the fo... Read More about Nitric oxide, stomatal closure and abiotic stress.

Assessing the failure of a community-based human-wildlife conflict mitigation project in Budongo Forest Reserve, Uganda (2007)
Journal Article
Webber, A. D., Hill, C. M., & Reynolds, V. (2007). Assessing the failure of a community-based human-wildlife conflict mitigation project in Budongo Forest Reserve, Uganda. Oryx, 41(2), 177-184. https://doi.org/10.1017/s0030605307001792

Primate crop raiding is a major cause of human-wildlife conflict around the forests of western Uganda. In an attempt to ameliorate the situation a conflict mitigation strategy was established in villages around the Budongo Forest Reserve in 2001. Liv... Read More about Assessing the failure of a community-based human-wildlife conflict mitigation project in Budongo Forest Reserve, Uganda.

"From the heart of my bottom": Negotiating humor in focus group discussions (2007)
Journal Article
Knight, L. V., Rees, C. E., & Wilkinson, C. (2007). "From the heart of my bottom": Negotiating humor in focus group discussions. Qualitative Health Research, 17(3), 411-422. https://doi.org/10.1177/1049732306298375

Reporting and analyzing interactional data collected during focus groups can be a significant challenge for qualitative health researchers. In this article, the authors explore the use of humor among focus group participants as one area of interactio... Read More about "From the heart of my bottom": Negotiating humor in focus group discussions.

Breed-associated variations in the sequence of the pig 3β- hydroxysteroid dehydrogenase gene (2007)
Journal Article
Cue, R. A., Nicolau-Solano, S., McGivan, J. D., Wood, J. D., & Doran, O. (2007). Breed-associated variations in the sequence of the pig 3β- hydroxysteroid dehydrogenase gene. Journal of Animal Science, 85(3), 571-576. https://doi.org/10.2527/jas.2006-366

The entire sequence of the pig 3β-hydroxysteroid dehydrogenase (3β-HSD) gene has recently become known. This gene is deemed to be important in androstenone metabolism in pig liver, and its defective expression has been shown to be related to androste... Read More about Breed-associated variations in the sequence of the pig 3β- hydroxysteroid dehydrogenase gene.

A proteomic investigation of glomerular podocytes from a Denys-Drash Syndrome patient with a mutation in the Wilms tumour suppressor gene WT1 (2007)
Journal Article
Van Den Heuver, L. P., Viney, R. L., Morrison, A. A., Ni, L., Mathieson, P. W., Saleem, M. A., & Ladomery, M. (2007). A proteomic investigation of glomerular podocytes from a Denys-Drash Syndrome patient with a mutation in the Wilms tumour suppressor gene WT1. Proteomics, 7(5), 804-815. https://doi.org/10.1002/pmic.200600666

Glomerular podocytes are essential for blood filtration in the kidney underpinned by their unique cytoskeletal morphology. An increasing number of kidney diseases are being associated with key podocyte abnormalities. The Wilms tumour suppressor gene... Read More about A proteomic investigation of glomerular podocytes from a Denys-Drash Syndrome patient with a mutation in the Wilms tumour suppressor gene WT1.

Simple sequence repeats reveal uneven distribution of genetic diversity in chloroplast genomes of Brassica oleracea L. and (n = 9) wild relatives (2007)
Journal Article
Allender, C. J., Allainguillaume, J., Lynn, J., & King, G. J. (2007). Simple sequence repeats reveal uneven distribution of genetic diversity in chloroplast genomes of Brassica oleracea L. and (n = 9) wild relatives. TAG Theoretical and Applied Genetics, 114(4), 609-618. https://doi.org/10.1007/s00122-006-0461-5

Diversity in the chloroplast genome of 171 accessions representing the Brassica 'C' (n = 9) genome, including domesticated and wild B. oleracea and nine inter-fertile related wild species, was investigated using six chloroplast SSR (microsatellite) m... Read More about Simple sequence repeats reveal uneven distribution of genetic diversity in chloroplast genomes of Brassica oleracea L. and (n = 9) wild relatives.

A study of retention and overloading of basic compounds with mixed-mode reversed-phase/cation-exchange columns in high performance liquid chromatography (2007)
Journal Article
Davies, N. H., Euerby, M. R., & McCalley, D. V. (2007). A study of retention and overloading of basic compounds with mixed-mode reversed-phase/cation-exchange columns in high performance liquid chromatography. Journal of Chromatography A, 1138(1-2), 65-72. https://doi.org/10.1016/j.chroma.2006.10.002

The retention and overload of bases were studied on two new mixed-mode, silica based phases possessing ionic carboxylate functionalities of different acidity embedded within a hydrophobic ligand (SiELC Primesep™). At low pH, good peak shapes were obt... Read More about A study of retention and overloading of basic compounds with mixed-mode reversed-phase/cation-exchange columns in high performance liquid chromatography.

Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors (2007)
Journal Article
Huang, T. H. M., Baker, J. A., Hancock, A. L., Brown, K. W., Chilukamarri, L., Malik, S., …Malik, K. (2007). Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors. Neoplasia, 9(11), 970-978. https://doi.org/10.1593/neo.07661

Wilms tumors (WTs) have a complex etiology, displaying genetic and epigenetic changes, including loss of imprinting (LOI) and tumor suppressor gene silencing. To identify new regions of epigenetic perturbation in WTs, we screened kidney and tumor DNA... Read More about Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors.

Signaling on the stigma: Potential new roles for ROS and NO in plant cell signaling (2007)
Journal Article
Hiscock, S. J., Bright, J., McInnis, S. M., Desikan, R., & Hancock, J. T. (2007). Signaling on the stigma: Potential new roles for ROS and NO in plant cell signaling. Plant Signaling and Behavior, 2(1), 23-24

Reactive oxygen species (ROS) and reactive nitrogen species, particularly NO, are key components of diverse signaling networks in animals and plants. We have recently shown that epidermal cells of stigmas from a range of different angiosperms accumul... Read More about Signaling on the stigma: Potential new roles for ROS and NO in plant cell signaling.