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All Outputs (91)

Oxygen is instrumental for biological signalling: An overview (2021)
Journal Article
Hancock, J. (2021). Oxygen is instrumental for biological signalling: An overview. Oxygen, 1(1), 3-15. https://doi.org/10.3390/oxygen1010002

Control of cellular function is extremely complex, being reliant on a wide range of components. Several of these are small oxygen-based molecules. Although reactive compounds containing oxygen are usually harmful to cells when accumulated to relative... Read More about Oxygen is instrumental for biological signalling: An overview.

Broken chocolate: Biomarkers as a method for delivering cocoa supply chain visibility (2021)
Journal Article
Lafargue, P., Rogerson, M., Parry, G. C., & Allainguillaume, J. (2022). Broken chocolate: Biomarkers as a method for delivering cocoa supply chain visibility. Supply Chain Management, 27(6), 728-741. https://doi.org/10.1108/SCM-11-2020-0583

Purpose: This paper examines the potential of “biomarkers” to provide immutable identification for food products (chocolate), providing traceability and visibility in the supply chain from retail product back to farm. Design/methodology/approach: Thi... Read More about Broken chocolate: Biomarkers as a method for delivering cocoa supply chain visibility.

Bioscience laboratory practicals, projects and placements in a Covid-19 world (2021)
Journal Article
Rolfe, V., & Adukwu, E. (2023). Bioscience laboratory practicals, projects and placements in a Covid-19 world. Journal of Biological Education, 57(3), 668-677. https://doi.org/10.1080/00219266.2021.1941187

The aim of this review is to discuss alternatives to the traditional practicals, undergraduate projects and student placements that are presently being disrupted by Covid-19. We focus on bioscience higher education (biology, biomedical sciences) with... Read More about Bioscience laboratory practicals, projects and placements in a Covid-19 world.

The effect of cold atmospheric plasma and linalool nanoemulsions against Escherichia coli O157:H7 and Salmonella on ready-to-eat chicken meat (2021)
Journal Article
González-González, C. R., Labo-Popoola, O., Delgado-Pando, G., Theodoridou, K., Doran, O., & Stratakos, A. C. (2021). The effect of cold atmospheric plasma and linalool nanoemulsions against Escherichia coli O157:H7 and Salmonella on ready-to-eat chicken meat. LWT - Food Science and Technology, 149, Article 111898. https://doi.org/10.1016/j.lwt.2021.111898

In this study, the antimicrobial efficiency of a novel low-voltage piezoelectric direct discharge generated cold plasma (CAP) and linalool-loaded nanoemulsion washing (LW) was assessed against Salmonella and Escherichia coli O157:H7 on ready-to-eat (... Read More about The effect of cold atmospheric plasma and linalool nanoemulsions against Escherichia coli O157:H7 and Salmonella on ready-to-eat chicken meat.

Prey availability and intraguild competition regulate the spatiotemporal dynamics of a modified large carnivore guild (2021)
Journal Article
Davis, R. S., Yarnell, R. W., Gentle, L. K., Uzal, A., Mgoola, W. O., & Stone, E. L. (2021). Prey availability and intraguild competition regulate the spatiotemporal dynamics of a modified large carnivore guild. Ecology and Evolution, 11(12), 7890-7904. https://doi.org/10.1002/ece3.7620

Effective conservation management requires an understanding of the spatiotemporal dynamics driving large carnivore density and resource partitioning. In African ecosystems, reduced prey populations and the loss of competing guild members, most notabl... Read More about Prey availability and intraguild competition regulate the spatiotemporal dynamics of a modified large carnivore guild.

Exploring the digital media ecology: Insights from a study of healthy diets and climate change communication on digital and social media (2021)
Journal Article
Weitkamp, E., Milani, E., Ridgway, A., & Wilkinson, C. (2021). Exploring the digital media ecology: Insights from a study of healthy diets and climate change communication on digital and social media. JCOM: Journal of Science Communication, 20(3), 1-22. https://doi.org/10.22323/2.20030202

This study explores the types of actors visible in the digital science communication landscape in the Netherlands, Serbia and the UK. Using the Koru model of science communication as a basis, we consider how science communicators craft their messages... Read More about Exploring the digital media ecology: Insights from a study of healthy diets and climate change communication on digital and social media.

Oxy-hydrogen gas: The rationale behind its use as a novel and sustainable treatment for COVID-19 and other respiratory diseases (2021)
Journal Article
Russell, G., Nenov, A., & Hancock, J. (2021). Oxy-hydrogen gas: The rationale behind its use as a novel and sustainable treatment for COVID-19 and other respiratory diseases. European Medical Journal, May 2021, https://doi.org/10.33590/emj/21-00027

Oxy-hydrogen gas (HHO) is a gaseous mixture of molecular hydrogen (H2) and molecular oxygen (O2) that is generated by the electrolysis of water and delivered in a 2:1 ratio (66% and 33%, respectively) through the use of non-invasive inhalation device... Read More about Oxy-hydrogen gas: The rationale behind its use as a novel and sustainable treatment for COVID-19 and other respiratory diseases.

Molecular hydrogen: Redox reactions and possible biological interactions (2021)
Journal Article
Hancock, J. T., LeBaron, T. W., & Russell, G. (2021). Molecular hydrogen: Redox reactions and possible biological interactions. Reactive Oxygen Species, 11, m17–m25. https://doi.org/10.20455/ros.2021.m.803

Molecular hydrogen (H2), either as a gas or as hydrogen-rich water (HRW), is suggested to be a useful treatment for a range of human diseases and also to improve agricultural output. It is often posited that H2 accomplishes its biological action, in... Read More about Molecular hydrogen: Redox reactions and possible biological interactions.

Mapping scrub vegetation cover from photogrammetric point clouds: A useful tool in reserve management (2021)
Journal Article
Vafidis, J., Lucksted, I., Gall, M., Maxfield, P., Meakin, K., & Steer, M. (2021). Mapping scrub vegetation cover from photogrammetric point clouds: A useful tool in reserve management. Ecology and Evolution, 11(11), 6789-6797. https://doi.org/10.1002/ece3.7527

Scrub vegetation is a valuable habitat and resource for wildlife, but if unmanaged can encroach and dominate adjacent habitats, reducing biodiversity value. A primary task in the management of terrestrial nature reserves in the UK is monitoring and c... Read More about Mapping scrub vegetation cover from photogrammetric point clouds: A useful tool in reserve management.

Use of machine learning-enabled scenario-based teaching in Haematology and Biomedical Science, as a replacement and supplement to traditional tools and in-person teaching during COVID-19 (2021)
Journal Article
May, J., Anderson, E., Clark, D., & Hull, J. (2021). Use of machine learning-enabled scenario-based teaching in Haematology and Biomedical Science, as a replacement and supplement to traditional tools and in-person teaching during COVID-19. British Journal of Haematology, 193(S1), 72

One of the biggest challenges during the COVID-19 pandemic has been maintaining student engagement and providing the best learning experience with limited face-to-face (FTF) contact, and social distancing requirements. Whilst multiple tools are avail... Read More about Use of machine learning-enabled scenario-based teaching in Haematology and Biomedical Science, as a replacement and supplement to traditional tools and in-person teaching during COVID-19.

Shedding smart light on the effectiveness of chemotherapy: using Raman spectroscopy and machine learning to differentiate the effects of Cytarabine toxicity and crosstalk of leukaemic and bone marrow stromal cells (2021)
Journal Article
Gynn, L., Lamb-Riddell, K., Cox, T., Hansen, M., Conway, M., & May, J. (2021). Shedding smart light on the effectiveness of chemotherapy: using Raman spectroscopy and machine learning to differentiate the effects of Cytarabine toxicity and crosstalk of leukaemic and bone marrow stromal cells. British Journal of Haematology, 193(S1), 46-47

Mesenchymal stromal cells (MSC) protect leukaemic cells from drug-induced toxicity within the bone marrow niche, with increasing evidence of leukaemic impact on supportive stroma. The nucleoside analogue, cytarabine (ara-C), is a front-line agent for... Read More about Shedding smart light on the effectiveness of chemotherapy: using Raman spectroscopy and machine learning to differentiate the effects of Cytarabine toxicity and crosstalk of leukaemic and bone marrow stromal cells.

Designing mini-games as micro-learning resources for professional development in multi-cultural organisations (2021)
Journal Article
Arnab, S., Walaszczyk, L., Lewis, M., Kernaghan-Andrews, S., Loizou, M., Masters, A., …Clarke, S. (2021). Designing mini-games as micro-learning resources for professional development in multi-cultural organisations. Electronic Journal of eLearning, 19(2), 44--58. https://doi.org/10.34190/ejel.19.2.2141

The need for self-directed learning for professional development drives an increase in the delivery of easy to use {\textquoteleft}just-in-time{\textquoteright} resources that respond to the often-dynamic workplace and work culture. This is especiall... Read More about Designing mini-games as micro-learning resources for professional development in multi-cultural organisations.

A literature survey of all volatiles from healthy human breath and bodily fluids: The human volatilome (2021)
Journal Article
Drabińska, N., Flynn, C., Ratcliffe, N., Belluomo, I., Myridakis, A., Gould, O., …Costello, B. D. L. (2021). A literature survey of all volatiles from healthy human breath and bodily fluids: The human volatilome. Journal of Breath Research, 15(3), 034001. https://doi.org/10.1088/1752-7163/abf1d0

This paper comprises an updated version of the 2014 review which reported 1846 volatile organic compounds (VOCs) identified from healthy humans. In total over 900 additional VOCs have been reported since the 2014 review and the VOCs from semen have b... Read More about A literature survey of all volatiles from healthy human breath and bodily fluids: The human volatilome.

Identification and distribution of novel badnaviral sequences integrated in the genome of cacao (Theobroma cacao) (2021)
Journal Article
Muller, E., Ullah, I., Dunwell, J. M., Daymond, A. J., Richardson, M., Allainguillaume, J., & Wetten, A. (2021). Identification and distribution of novel badnaviral sequences integrated in the genome of cacao (Theobroma cacao). Scientific Reports, 11(1), Article 8270. https://doi.org/10.1038/s41598-021-87690-1

Theobroma cacao is one of the most economically important tropical trees, being the source of chocolate. As part of an ongoing study to understand the diversity of the badnavirus complex, responsible for the cacao swollen shoot virus disease in West... Read More about Identification and distribution of novel badnaviral sequences integrated in the genome of cacao (Theobroma cacao).

Inactivation of Listeria monocytogenes and Salmonella on stainless steel by a piezoelectric cold atmospheric plasma generator (2021)
Journal Article
Gonzalez-Gonzalez, C. R., Hindle, B. J., Saad, S., & Stratakos, A. C. (2021). Inactivation of Listeria monocytogenes and Salmonella on stainless steel by a piezoelectric cold atmospheric plasma generator. Applied Sciences, 11(8), Article 3567. https://doi.org/10.3390/app11083567

Cold atmospheric pressure plasma (CAP) is a novel non‐thermal technology that is gain-ing increasing importance as a decontamination method. Stainless steel is a widespread food contact surface used in food‐processing environments. In this study, for... Read More about Inactivation of Listeria monocytogenes and Salmonella on stainless steel by a piezoelectric cold atmospheric plasma generator.

CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer (2021)
Journal Article
Uzor, S., Porazinski, S., Li, L., Clark, B., Ajiro, M., Iida, K., …Ladomery, M. (2021). CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer. Scientific Reports, 11(1), Article 7963. https://doi.org/10.1038/s41598-021-86908-6

Dysregulation of alternative splicing is a feature of cancer, both in aetiology and progression. It occurs because of mutations in splice sites or sites that regulate splicing, or because of the altered expression and activity of splice factors and o... Read More about CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer.

‘We tend to get pad happy’: A qualitative study of health practitioners’ perspectives on the quality of continence care for older people in hospital (2021)
Journal Article
Percival, J., Abbott, K., Allain, T., Bradley, R., Cramp, F., Donovan, J. L., …Cotterill, N. (2021). ‘We tend to get pad happy’: A qualitative study of health practitioners’ perspectives on the quality of continence care for older people in hospital. BMJ Open Quality, 10(2), Article e001380. https://doi.org/10.1136/bmjoq-2021-001380

Bladder and bowel control difficulties affect 20% and 10% of the UK population, respectively, touch all age groups and are particularly prevalent in the older (65+ years) population. However, the quality of continence care is often poor, compromising... Read More about ‘We tend to get pad happy’: A qualitative study of health practitioners’ perspectives on the quality of continence care for older people in hospital.

5-aminosalicylic acid inhibits stem cell function in human adenoma derived cells: Implications for chemoprophylaxis in colorectal tumorigenesis (2021)
Journal Article
Dixon, S. W., Collard, T. J., Mortensson, E. M. H., Legge, D. N., Chambers, A. C., Greenhough, A., …Williams, A. C. (2021). 5-aminosalicylic acid inhibits stem cell function in human adenoma derived cells: Implications for chemoprophylaxis in colorectal tumorigenesis. British Journal of Cancer, 124, 1959–1969. https://doi.org/10.1038/s41416-021-01354-5

Background: Most colorectal cancers (CRC) arise sporadically from precursor lesions: colonic polyps. Polyp resection prevents progression to CRC. Risk of future polyps is proportional to the number and size of polyps detected at screening, allowing i... Read More about 5-aminosalicylic acid inhibits stem cell function in human adenoma derived cells: Implications for chemoprophylaxis in colorectal tumorigenesis.

Developing a systematic method for extraction of microplastics in soils (2021)
Journal Article
Radford, F., Zapata-Restrepo, L. M., Horton, A. A., Hudson, M. D., Shaw, P. J., & Williams, I. D. (2021). Developing a systematic method for extraction of microplastics in soils. Analytical Methods, 13(14), 1695-1705. https://doi.org/10.1039/d0ay02086a

Microplastics are an environmental issue of global concern. Although they have been found in a range of environments worldwide, their contamination in the terrestrial environment is poorly understood. The lack of standardised methods for their detect... Read More about Developing a systematic method for extraction of microplastics in soils.