All Outputs (9)

The clinical impact of serious respiratory disease in children under the age of two years during the 2021-2022 bronchiolitis season in England, Scotland and Ireland (2023)
Journal Article
Williams, T. C., Marlow, R., Hardelid, P., Lyttle, M. D., Lewis, K. M., Mpamhanga, C. D., …Roland, D. (in press). The clinical impact of serious respiratory disease in children under the age of two years during the 2021-2022 bronchiolitis season in England, Scotland and Ireland. Journal of Infectious Diseases, https://doi.org/10.1093/infdis/jiad551

Interventions introduced to reduce the spread of SARS-CoV-2 led to a widespread reduction in childhood infections. However, from spring 2021 onwards the United Kingdom and Ireland experienced an unusual out-of-season epidemic of respiratory disease.... Read More about The clinical impact of serious respiratory disease in children under the age of two years during the 2021-2022 bronchiolitis season in England, Scotland and Ireland.

Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: A qualitative study (2023)
Journal Article
Craig, S., Xu, Y., Robas, K., Iramain, R., Yock-Corrales, A., Soto-Martinez, M. E., …Babl, F. E. (2023). Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: A qualitative study. BMJ Open Respiratory Research, 10(1), Article e001723. https://doi.org/10.1136/bmjresp-2023-001723

Objective To identify the outcomes considered important, and factors influencing the patient experience, for parents and caregivers of children presenting to hospital with a severe acute exacerbation of asthma. This work contributes to the outcome-id... Read More about Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: A qualitative study.

Applying clinical decision aids for the assessment and management of febrile infants presenting to emergency care in the UK and Ireland: Febrile Infant Diagnostic Assessment and Outcome (FIDO) Study protocol (2023)
Journal Article
Umana, E., Mills, C., Norman-Bruce, H., Wilson, K., Mitchell, H., Mcfetridge, L., …Waterfield, T. (2023). Applying clinical decision aids for the assessment and management of febrile infants presenting to emergency care in the UK and Ireland: Febrile Infant Diagnostic Assessment and Outcome (FIDO) Study protocol. BMJ Open, 13(9), Article e075823. https://doi.org/10.1136/bmjopen-2023-075823

Introduction Febrile infants 90 days and younger are at risk of invasive bacterial infections (bacteraemia and meningitis) and urinary tract infections. Together this is previously termed serious bacterial infection with an incidence of approximately... Read More about Applying clinical decision aids for the assessment and management of febrile infants presenting to emergency care in the UK and Ireland: Febrile Infant Diagnostic Assessment and Outcome (FIDO) Study protocol.

Comparison of injury patterns and interventions between adolescent, adult and paediatric trauma cases: A cross-sectional review of TARN data (2023)
Journal Article
Mullen, S., Tolson, A., Bouamra, O., Watson, B., Lyttle, M. D., Roland, D., & James, D. (2023). Comparison of injury patterns and interventions between adolescent, adult and paediatric trauma cases: A cross-sectional review of TARN data. BMJ Open, 13(5), Article e064101. https://doi.org/10.1136/bmjopen-2022-064101

Objectives The aim is to compare adolescent (10-24.99 years) trauma patterns and interventions to adult (≥25) and paediatric cases (

A diagnostic accuracy study to evaluate standard rapid diagnostic test (RDT) alone to safely rule out imported malaria in children presenting to UK emergency departments (2023)
Journal Article
Bird, C., Hayward, G. N., Turner, P. J., Merrick, V., Lyttle, M. D., Mullen, N., & Fanshawe, T. R. (2023). A diagnostic accuracy study to evaluate standard rapid diagnostic test (RDT) alone to safely rule out imported malaria in children presenting to UK emergency departments. Journal of the Pediatric Infectious Diseases Society, 12(5), 290-297. https://doi.org/10.1093/jpids/piad024

BACKGROUND: Microscopy is the gold standard for malaria diagnosis but is dependent on trained personnel. Rapid diagnostic tests (RDTs) form the mainstay of diagnosis in endemic areas without access to high-quality microscopy. We aimed to evaluate whe... Read More about A diagnostic accuracy study to evaluate standard rapid diagnostic test (RDT) alone to safely rule out imported malaria in children presenting to UK emergency departments.

Factors related to adverse long-term outcomes after mild traumatic brain injury in children: A scoping review (2023)
Journal Article
Ijaz, S., Scott, L., Dawson, S., Wilson, R., Jackson, J., Birnie, K., …Mytton, J. (in press). Factors related to adverse long-term outcomes after mild traumatic brain injury in children: A scoping review. Archives of Disease in Childhood, 108(6), 492-497. https://doi.org/10.1136/archdischild-2022-325202

Objective: To identify demographic, premorbid and injury-related factors, or biomarkers associated with long-term (≥3 months) adverse outcomes in children after mild traumatic brain injury (mTBI). Design: Scoping review of literature. Patients: Child... Read More about Factors related to adverse long-term outcomes after mild traumatic brain injury in children: A scoping review.

International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: A qualitative interview study (2023)
Journal Article
Gray, C. S., Xu, Y., Babl, F. E., Dalziel, S., Powell, C. V., Chong, S., …Craig, S. (2023). International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: A qualitative interview study. BMJ Open Respiratory Research, 10(1), Article e001502. https://doi.org/10.1136/bmjresp-2022-001502

Background: Acute exacerbations of asthma are common in children, however, treatment decisions for severe exacerbations are challenging due to a lack of robust evidence. In order to create more robust research, a core set of outcome measures needs to... Read More about International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: A qualitative interview study.

Assessment and management of children with head injury: Practice and opinion (2023)
Journal Article
Proctor, A., Voss, S., Lyttle, M., & Benger, J. (2023). Assessment and management of children with head injury: Practice and opinion. Journal of Paramedic Practice, 15(2), 58-64. https://doi.org/10.12968/jpar.2023.15.2.58

Background: Head injury is common in children with approximately 700 000 attendances at emergency departments annually; one-third are conveyed by ambulance. However, 75% of them are discharged with no treatment. Most head-injured children could be ma... Read More about Assessment and management of children with head injury: Practice and opinion.

The journey back to normality: Support systems and posttrauma needs following exposure to single-incident trauma among children and adolescents (2023)
Journal Article
Haag, K., Hiller, R., McGuire, R., Lyttle, M., & Halligan, S. L. (2023). The journey back to normality: Support systems and posttrauma needs following exposure to single-incident trauma among children and adolescents. Journal of Traumatic Stress, 36(1), 218-229. https://doi.org/10.1002/jts.22902

Social support has been linked to posttrauma adjustment in children and adolescents, but the components of good support remain poorly defined. We conducted qualitative interviews with 30 youths aged 7–16 years after being admitted to a hospital follo... Read More about The journey back to normality: Support systems and posttrauma needs following exposure to single-incident trauma among children and adolescents.