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Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: A PERUKI service evaluation (2022)
Journal Article
Hartshorn, S., Durnin, S., Lyttle, M. D., & Barrett, M. (2022). Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: A PERUKI service evaluation. BMJ Paediatrics Open, 6(1), https://doi.org/10.1136/bmjpo-2021-001273

Background Management of acute pain should commence at the earliest opportunity, as it has many short-term and long-term consequences. A research priority of Paediatric Emergency Research in the UK and Ireland (PERUKI) was to examine paediatric pain... Read More about Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: A PERUKI service evaluation.

Validating clinical practice guidelines for the management of febrile infants presenting to the emergency department in the UK and Ireland (2022)
Journal Article
Waterfield, T., Lyttle, M. D., Munday, C., Foster, S., McNulty, M., Platt, R., …Roland, D. (2022). Validating clinical practice guidelines for the management of febrile infants presenting to the emergency department in the UK and Ireland. Archives of Disease in Childhood, 107(4), 329-334. https://doi.org/10.1136/archdischild-2021-322586

Objective To report the performance of clinical practice guidelines (CPG) in the diagnosis of serious/invasive bacterial infections (SBI/IBI) in infants presenting with a fever to emergency care in the UK and Ireland. Two CPGs were from the National... Read More about Validating clinical practice guidelines for the management of febrile infants presenting to the emergency department in the UK and Ireland.

Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop (2022)
Journal Article
McNamara, P. S., Fernandes, R. M., Rosala-Hallas, A., Jones, A. P., Williamson, P. R., Bedson, E., …McNamara, P. S. (2022). Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop. BMJ Open, 12(3), https://doi.org/10.1136/bmjopen-2021-052943

Objectives The objective of this study was to develop a core outcome set (COS) for use in future clinical trials in bronchiolitis. We wanted to find out which outcomes are important to healthcare professionals (HCPs) and to parents and which outcomes... Read More about Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop.

Periorbital and orbital cellulitis in children: a survey of emergency physicians and analysis of clinical practice guidelines across the PERUKI network (2022)
Journal Article
Tolhurst-Cleaver, M., Evans, J., Waterfield, T., Adamson, J., Marlow, R., Lyttle, M. D., & Roland, D. (in press). Periorbital and orbital cellulitis in children: a survey of emergency physicians and analysis of clinical practice guidelines across the PERUKI network. Emergency Medicine Journal, emermed-2021-211713. https://doi.org/10.1136/emermed-2021-211713

Background Due to limited evidence to guide management of periorbital cellulitis (POC), we surveyed current practice and assessed quality and consistency of local clinical practice guidelines (CPGs) to highlight future research priorities. Methods... Read More about Periorbital and orbital cellulitis in children: a survey of emergency physicians and analysis of clinical practice guidelines across the PERUKI network.

Point-of-care testing in paediatric settings in the UK and Ireland: A cross-sectional study (2022)
Journal Article
Pandey, M., Lyttle, M. D., Cathie, K., Munro, A., Waterfield, T., Roland, D., …On behalf of GAPRUKI, PERUKI, . (2022). Point-of-care testing in paediatric settings in the UK and Ireland: A cross-sectional study. BMC Emergency Medicine, 22(1), https://doi.org/10.1186/s12873-021-00556-7

Background: Point-of-care testing (POCT) is diagnostic testing performed at or near to the site of the patient. Understanding the current capacity, and scope, of POCT in this setting is essential in order to respond to new research evidence which may... Read More about Point-of-care testing in paediatric settings in the UK and Ireland: A cross-sectional study.

Amoxicillin duration and dose for community-acquired pneumonia in children: the CAP-IT factorial non-inferiority RCT (2021)
Journal Article
Barratt, S., Bielicki, J. A., Dunn, D., Faust, S. N., Finn, A., Harper, L., …Sharland, M. (2021). Amoxicillin duration and dose for community-acquired pneumonia in children: the CAP-IT factorial non-inferiority RCT. Health Technology Assessment, 25(60), 1-72. https://doi.org/10.3310/hta25600

Background: Data are limited regarding the optimal dose and duration of amoxicillin treatment for community-acquired pneumonia in children. Objectives: To determine the efficacy, safety and impact on antimicrobial resistance of shorter (3-day) and lo... Read More about Amoxicillin duration and dose for community-acquired pneumonia in children: the CAP-IT factorial non-inferiority RCT.

Effect of Amoxicillin dose and treatment duration on the need for antibiotic re-treatment in children with Community-Acquired Pneumonia: The CAP-IT randomized clinical trial (2021)
Journal Article
Bielicki, J. A., Stöhr, W., Barratt, S., Dunn, D., Naufal, N., Roland, D., …PERUKI, GAPRUKI, and the CAP-IT Trial Group, . (2021). Effect of Amoxicillin dose and treatment duration on the need for antibiotic re-treatment in children with Community-Acquired Pneumonia: The CAP-IT randomized clinical trial. Journal of the American Medical Association, 326(17), 1713-1724. https://doi.org/10.1001/jama.2021.17843

Importance: The optimal dose and duration of oral amoxicillin for children with community-acquired pneumonia (CAP) are unclear. Objective: To determine whether lower-dose amoxicillin is noninferior to higher dose and whether 3-day treatment is noninf... Read More about Effect of Amoxicillin dose and treatment duration on the need for antibiotic re-treatment in children with Community-Acquired Pneumonia: The CAP-IT randomized clinical trial.

A bibliometric analysis of global pediatric emergency medicine research networks (2021)
Journal Article
Barrett, M. J., Dalziel, S., Lyttle, M., & O'Sullivan, R. (2022). A bibliometric analysis of global pediatric emergency medicine research networks. Pediatric Emergency Care, 38(4), e1179-e1184. https://doi.org/10.1097/pec.0000000000002543

Objectives During the last 3 decades newly formed pediatric emergency medicine (PEM) research networks have been publishing research. A desire of these networks is to produce and disseminate research to improve patient health and outcomes. The aims... Read More about A bibliometric analysis of global pediatric emergency medicine research networks.

Comparative analysis of major incident triage tools in children: A UK population-based analysis (2021)
Journal Article
Vassallo, J., Chernbumroong, S., Malik, N., Xu, Y., Keene, D., Gkoutos, G., …Smith, J. (in press). Comparative analysis of major incident triage tools in children: A UK population-based analysis. Emergency Medicine Journal, https://doi.org/10.1136/emermed-2021-211706

Introduction Triage is a key principle in the effective management of major incidents. There is currently a paucity of evidence to guide the triage of children. The aim of this study was to perform a comparative analysis of nine adult and paediatric... Read More about Comparative analysis of major incident triage tools in children: A UK population-based analysis.

Structures of paediatric pain management: A PERUKI service evaluation study (2021)
Journal Article
Durnin, S., Barrett, M. J., Lyttle, M. D., & Hartshorn, S. (2021). Structures of paediatric pain management: A PERUKI service evaluation study. BMJ Paediatrics Open, 5(1), https://doi.org/10.1136/bmjpo-2021-001159

Background Pain is very common in childhood emergency department (ED) attendances, but is under-recognised and undertreated. Sequential national paediatric analgesia audits demonstrate suboptimal outcomes in several domains. The Donabedian framework... Read More about Structures of paediatric pain management: A PERUKI service evaluation study.

Retrospective observational study of neonatal attendances to a children's emergency department (2021)
Journal Article
Blakey, S. J., Lyttle, M. D., & Magnus, D. (2021). Retrospective observational study of neonatal attendances to a children's emergency department. Acta Paediatrica, 110(11), 2968-2975. https://doi.org/10.1111/apa.16039

Aim Attendances to emergency departments (EDs) in the UK are increasing, particularly for younger children. Community services are under increasing pressure and parents may preferentially bring their babies to the ED, even for non-urgent problems. T... Read More about Retrospective observational study of neonatal attendances to a children's emergency department.

Need for recovery and physician well-being in emergency departments: National survey findings (2021)
Journal Article
Cottey, L., Roberts, T., Graham, B., Horner, D., Latour, J. M., Enki, D., …Stevens, K. N. (2021). Need for recovery and physician well-being in emergency departments: National survey findings. European Journal of Emergency Medicine, 28(5), 386-393. https://doi.org/10.1097/mej.0000000000000850

Background and importance Need for recovery (NFR) describes an individual's need to physically and psychologically recuperate following a period of work. Physicians working in emergency departments (EDs) have higher NFR scores than other occupational... Read More about Need for recovery and physician well-being in emergency departments: National survey findings.

Psychological distress and trauma during the COVID-19 pandemic: survey of doctors practising anaesthesia, intensive care medicine, and emergency medicine in the United Kingdom and Republic of Ireland (2021)
Journal Article
Kane, L., Mackenzie, L., Sharma Hajela, S., Phizacklea, J., Malik, K., Mathai, N., …Carlton, E. (2021). Psychological distress and trauma during the COVID-19 pandemic: survey of doctors practising anaesthesia, intensive care medicine, and emergency medicine in the United Kingdom and Republic of Ireland. British Journal of Anaesthesia, 127(2), e78-e80. https://doi.org/10.1016/j.bja.2021.05.017

Psychological distress during the acceleration phase of the COVID-19 pandemic: A survey of doctors practising in emergency medicine, anaesthesia and intensive care medicine in the UK and Ireland (2021)
Journal Article
Roberts, T., Daniels, J., Hulme, W., Hirst, R., Horner, D., Lyttle, M. D., …Carlton, E. (2021). Psychological distress during the acceleration phase of the COVID-19 pandemic: A survey of doctors practising in emergency medicine, anaesthesia and intensive care medicine in the UK and Ireland. Emergency Medicine Journal, 38(6), 450-459. https://doi.org/10.1136/emermed-2020-210438

Objective: To quantify psychological distress experienced by emergency, anaesthetic and intensive care doctors during the acceleration phase of COVID-19 in the UK and Ireland. Methods: Initial cross-sectional electronic survey distributed during acce... Read More about Psychological distress during the acceleration phase of the COVID-19 pandemic: A survey of doctors practising in emergency medicine, anaesthesia and intensive care medicine in the UK and Ireland.

Mortality in adolescent trauma: A comparison of children's, mixed and adult major trauma centres (2021)
Journal Article
Evans, J., Murch, H., Begley, R., Roland, D., Lyttle, M. D., Bouamra, O., & Mullen, S. (2021). Mortality in adolescent trauma: A comparison of children's, mixed and adult major trauma centres. Emergency Medicine Journal, 38(7), 488-494. https://doi.org/10.1136/emermed-2020-210384

Objective: We aimed to compare adolescent mortality rates between different types of major trauma centre (MTC or level 1; adult, children's and mixed). Methods: Data were obtained from TARN (Trauma Audit Research Network) from English sites over a 6-... Read More about Mortality in adolescent trauma: A comparison of children's, mixed and adult major trauma centres.

A survey of mHealth use from a physician perspective in paediatric emergency care in the UK and Ireland (2021)
Journal Article
Jahn, H. K., Jahn, I. H. J., Behringer, W., Lyttle, M. D., & Roland, D. (2021). A survey of mHealth use from a physician perspective in paediatric emergency care in the UK and Ireland. European Journal of Pediatrics, 180, 2409–2418. https://doi.org/10.1007/s00431-021-04023-0

Abstract: There has been a drive towards increased digitalisation in healthcare. The aim was to provide a snapshot of current apps, instant messaging, and smartphone photography use in paediatric emergency care. A web-based self-report questionnaire... Read More about A survey of mHealth use from a physician perspective in paediatric emergency care in the UK and Ireland.

Ingestion of metallic foreign bodies: A Paediatric Emergency Research in the United Kingdom and Ireland survey of current practice and hand-held metal detector use (2021)
Journal Article
Lafferty, M., Lyttle, M. D., Mullen, N., & PERUKI, . (2021). Ingestion of metallic foreign bodies: A Paediatric Emergency Research in the United Kingdom and Ireland survey of current practice and hand-held metal detector use. Journal of Paediatrics and Child Health, 57(6), 867-871. https://doi.org/10.1111/jpc.15343

Aim: To describe variation in the initial management of children presenting to Emergency Departments (ED) with coins lodged in the oesophagus. To determine the usage of hand-held metal detectors (HHMDs) in EDs, including their role in clinical decisi... Read More about Ingestion of metallic foreign bodies: A Paediatric Emergency Research in the United Kingdom and Ireland survey of current practice and hand-held metal detector use.

Seroprevalence of SARS-CoV-2 antibodies in children of United Kingdom healthcare workers: A prospective multicentre cohort study protocol (2020)
Journal Article
Corr, M., Christie, S., Watson, C., Maney, J., Fairley, D., Ladhani, S. N., …Waterfield, T. (2020). Seroprevalence of SARS-CoV-2 antibodies in children of United Kingdom healthcare workers: A prospective multicentre cohort study protocol. BMJ Open, 10(11), https://doi.org/10.1136/bmjopen-2020-041661

Background: A novel coronavirus SARS-CoV-2 has been responsible for a worldwide pandemic. Children typically have very mild, or no, symptoms of infection. This makes estimations of seroprevalence in children difficult. Research is therefore required... Read More about Seroprevalence of SARS-CoV-2 antibodies in children of United Kingdom healthcare workers: A prospective multicentre cohort study protocol.

Seroprevalence of SARS-CoV-2 antibodies in children: A prospective multicentre cohort study (2020)
Journal Article
Waterfield, T., Watson, C., Moore, R., Ferris, K., Tonry, C., Watt, A., …Christie, S. (2021). Seroprevalence of SARS-CoV-2 antibodies in children: A prospective multicentre cohort study. Archives of Disease in Childhood, 106(7), 680-686. https://doi.org/10.1136/archdischild-2020-320558

Background: Studies based on molecular testing of oral/nasal swabs underestimate SARS-CoV-2 infection due to issues with test sensitivity, test timing and selection bias. The objective of this study was to report the presence of SARS-CoV-2 antibodies... Read More about Seroprevalence of SARS-CoV-2 antibodies in children: A prospective multicentre cohort study.