All Outputs (3)

Maleidride biosynthesis - construction of dimeric anhydrides - more than just heads or tails (2022)
Journal Article
Williams, K., Szwalbe, A. J., de Mattos-Shipley, K. M. J., Bailey, A. M., Cox, R. J., & Willis, C. L. (2022). Maleidride biosynthesis - construction of dimeric anhydrides - more than just heads or tails. Natural Product Reports, 40(1), 128-157. https://doi.org/10.1039/d2np00041e

Covering: up to early 2022 Maleidrides are a family of polyketide-based dimeric natural products isolated from fungi. Many maleidrides possess significant bioactivities, making them attractive pharmaceutical or agrochemical lead compounds. Their unus... Read More about Maleidride biosynthesis - construction of dimeric anhydrides - more than just heads or tails.

Cloning and expression of Burkholderia polyyne biosynthetic gene clusters in Paraburkholderia hosts provides a strategy for biopesticide development (2022)
Journal Article
Petrova, Y. D., Zhao, J., Webster, G., Mullins, A. J., Williams, K., Alswat, A. S., …Mahenthiralingam, E. (2022). Cloning and expression of Burkholderia polyyne biosynthetic gene clusters in Paraburkholderia hosts provides a strategy for biopesticide development. Microbial Biotechnology, 15(10), 2547-2561. https://doi.org/10.1111/1751-7915.14106

Burkholderia have potential as biocontrol agents because they encode diverse biosynthetic gene clusters (BGCs) for a range of antimicrobial metabolites. Given the opportunistic pathogenicity associated with Burkholderia species, heterologous BGC expr... Read More about Cloning and expression of Burkholderia polyyne biosynthetic gene clusters in Paraburkholderia hosts provides a strategy for biopesticide development.

In silico analyses of maleidride biosynthetic gene clusters (2022)
Journal Article
Williams, K., de Mattos-Shipley, K. M., Willis, C. L., & Bailey, A. M. (2022). In silico analyses of maleidride biosynthetic gene clusters. Fungal Biology and Biotechnology, 9(1), Article 2. https://doi.org/10.1186/s40694-022-00132-z

Maleidrides are a family of structurally related fungal natural products, many of which possess diverse, potent bioactivities. Previous identification of several maleidride biosynthetic gene clusters, and subsequent experimental work, has determined... Read More about In silico analyses of maleidride biosynthetic gene clusters.