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Outputs (77)

Exploring serendipitous dialogue (2014)
Journal Article
Weitkamp, E. (2014). Exploring serendipitous dialogue. JCOM: Journal of Science Communication, 13(04),

Over the past decades there has been an increasing recognition of the need to promote dialogue between science and society. Often this takes the form of formal processes, such as citizen’s juries, that are designed to allow the public to contribut... Read More about Exploring serendipitous dialogue.

The impact of pressure and frictional heating on retention, selectivity and efficiency in ultra-high-pressure liquid chromatography (2014)
Journal Article
McCalley, D. V. (2014). The impact of pressure and frictional heating on retention, selectivity and efficiency in ultra-high-pressure liquid chromatography. Trends in Analytical Chemistry, 63, 31-43. https://doi.org/10.1016/j.trac.2014.06.024

© 2014 Elsevier B.V. The effects of pressure and frictional heating deserve serious consideration in ultra-high-pressure liquid chromatography (UHPLC) separations, as the pressures used can be three times greater than those in conventional high-perfo... Read More about The impact of pressure and frictional heating on retention, selectivity and efficiency in ultra-high-pressure liquid chromatography.

Triple negative breast cancer: The role of metabolic pathways (2014)
Journal Article
Dean, S. J., & Rhodes, A. (2014). Triple negative breast cancer: The role of metabolic pathways. Malaysian Journal of Pathology, 36(3), 155-162

The incidence of breast cancer in Malaysia and other Asian countries is on the increase, reflecting lifestyle changes some of which are known risk factors for the development of breast cancer. Most breast cancers are amenable to adjuvant therapies th... Read More about Triple negative breast cancer: The role of metabolic pathways.

Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells (2014)
Journal Article
Malik, K., Deery, M. J., Brown, K. W., Heesom, K. J., Melegh, Z., Vieira, G. C., …Malik, K. T. (2015). Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells. Molecular Oncology, 9(3), 617-627. https://doi.org/10.1016/j.molonc.2014.10.015

© 2014 The Authors. Approximately half of poor prognosis neuroblastomas (NBs) are characterized by pathognomonic MYCN gene amplification and MYCN over-expression. Here we present data showing that short-interfering RNA mediated depletion of the prote... Read More about Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells.

Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer (2014)
Journal Article
Mavrou, A., Brakspear, K., Hamdollah-Zadeh, M., Damodaran, G., Babaei-Jadidi, R., Oxley, J., …Oltean, S. (2015). Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer. Oncogene, 34, 4311-4319. https://doi.org/10.1038/onc.2014.360

© 2015 Macmillan Publishers Limited. All rights reserved. Angiogenesis is required for tumour growth and is induced principally by vascular endothelial growth factor A (VEGF-A). VEGF-A pre-mRNA is alternatively spliced at the terminal exon to produce... Read More about Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer.

Assessing the value of imperfect biocontainment nationally: Rapeseed in the United Kingdom as an exemplar (2014)
Journal Article
Ford, C. S., Allainguillaume, J., Fu, T. R., Mitchley, J., & Wilkinson, M. J. (2015). Assessing the value of imperfect biocontainment nationally: Rapeseed in the United Kingdom as an exemplar. New Phytologist, 205(3), 1342-1349. https://doi.org/10.1111/nph.13131

© 2014 New Phytologist Trust. Paternal biocontainment methods (PBMs) act by preventing pollen-mediated transgene flow. They are compromised by transgene escape via the crop-maternal line. We therefore assess the efficacy of PBMs for transgenic rapese... Read More about Assessing the value of imperfect biocontainment nationally: Rapeseed in the United Kingdom as an exemplar.

City life makes females fussy: Sex differences in habitat use of temperate bats in urban areas (2014)
Journal Article
Park, K. J., Mayhew, R. J., Lintott, P., Bunnefeld, N., Fuentes-Montemayor, E., Minderman, J., & Olley, L. (2014). City life makes females fussy: Sex differences in habitat use of temperate bats in urban areas. Royal Society Open Science, 1(3), Article 140200. https://doi.org/10.1098/rsos.140200

© 2014 The Authors. Urbanization is a major driver of the global loss of biodiversity; to mitigate its adverse effects, it is essential to understand what drives species' patterns of habitat use within the urban matrix. While many animal species are... Read More about City life makes females fussy: Sex differences in habitat use of temperate bats in urban areas.

Topographical variation reduces phenological mismatch between a butterfly and its nectar source (2014)
Journal Article
Hindle, B. J., Kerr, C. L., Richards, S. A., & Willis, S. G. (2015). Topographical variation reduces phenological mismatch between a butterfly and its nectar source. Journal of Insect Conservation, 19(2), 227-236. https://doi.org/10.1007/s10841-014-9713-x

© 2014, Springer International Publishing Switzerland. The timing of many biological events, including butterfly imago emergence, has advanced under climate change, with the rate of these phenological changes often differing among taxonomic groups. S... Read More about Topographical variation reduces phenological mismatch between a butterfly and its nectar source.

Direct mixing of atomistic solutes and coarse-grained water (2014)
Journal Article
Orsi, M., Ding, W., & Palaiokostas, M. (2014). Direct mixing of atomistic solutes and coarse-grained water. Journal of Chemical Theory and Computation, 10(10), 4684-4693. https://doi.org/10.1021/ct500065k

© 2014 American Chemical Society. We present a new dual-resolution approach for coupling atomistic and coarse-grained models in molecular dynamics simulations of hydrated systems. In particular, a coarse-grained point dipolar water model is used to s... Read More about Direct mixing of atomistic solutes and coarse-grained water.