Differentiation of SH-SY5Y neuroblastoma cells using retinoic acid and BDNF: A model for neuronal and synaptic differentiation in neurodegeneration (2024)
Journal Article
Targett, I. L., Crompton, L. A., Conway, M. E., & Craig, T. J. (in press). Differentiation of SH-SY5Y neuroblastoma cells using retinoic acid and BDNF: A model for neuronal and synaptic differentiation in neurodegeneration. In Vitro Cellular and Developmental Biology - Animal,

There has been much interest in the use of cell culture models of neurones, to avoid the animal welfare and cost issues of using primary and human-induced pluripotent stem cell (hiPSC)-derived neurones respectively. The human neuroblastoma cell line,... Read More about Differentiation of SH-SY5Y neuroblastoma cells using retinoic acid and BDNF: A model for neuronal and synaptic differentiation in neurodegeneration.

Human stem cell-derived ventral midbrain astrocytes exhibit a region-specific secretory profile (2023)
Journal Article
Crompton, L., McComish, S. F., Steward, T., Whitcomb, D., Lane, J., & Caldwell, M. (2023). Human stem cell-derived ventral midbrain astrocytes exhibit a region-specific secretory profile. Brain Communications, 5(2), https://doi.org/10.1093/braincomms/fcad114

This scientific commentary refers to ‘Human stem cell-derived astrocytes exhibit region-specific heterogeneity in their secretory profiles’, by Clarke et al. (https://doi.org/10.1093/brain/awaa258) in Brain.