Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells (2023)
Journal Article
Robson, J. L., Thorn, R. M. S., Williams, A. C., Collard, T. J., & Qualtrough, D. (2023). Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells. Scientific Reports, 13(1), Article 17291. https://doi.org/10.1038/s41598-023-44130-6

Colorectal cancer (CRC) is a significant global health burden with a rising incidence worldwide. Distinct bacterial populations are associated with CRC development and progression, and it is thought that the relationship between CRC and associated gu... Read More about Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells.

The control of pathogens in stored rainwater using direct electrochemical activation (2022)
Conference Proceeding
Clayton, G., Fox, B., Steer, M., Thorn, R., & Reynolds, D. (2022). The control of pathogens in stored rainwater using direct electrochemical activation. In IWRA Proceedings

Purpose of study or research hypothesis: The main study aim was to control waterborne pathogens using small-scale direct electrochemical activation. Key issue(s) or problem(s) addressed: Rainwater harvesting systems enable households o... Read More about The control of pathogens in stored rainwater using direct electrochemical activation.

Managing biofilms in ultrafiltration membranes within a point-of-use drinking water system (2022)
Presentation / Conference
Clayton, G., Thorn, R., & Reynolds, D. (2022, December). Managing biofilms in ultrafiltration membranes within a point-of-use drinking water system. Presented at IWA Biofilms Conference 2022, Phuket, Thailand

Clean water for all (2022)
Digital Artefact
Clayton, G., Steven, J., Thorn, R., & Reynolds, D. (2022). Clean water for all. [Website]

The World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF) estimated that, as of 2020, 2 billion people across the globe did not have access to safely managed drinking water. Ideally, safely managed drinking water should b... Read More about Clean water for all.

Managing potential pathogens in stored rainwater using small-scale in-situ electrochemical activation (2022)
Presentation / Conference
Clayton, G., Fox, B., Steer, M., Thorn, R., & Reynolds, D. (2022, September). Managing potential pathogens in stored rainwater using small-scale in-situ electrochemical activation. Presented at International Water Association World Water Congress and Exhibition, Copenhagen

Rainwater can be a lifeline for many people who do not have piped water supplies, experience dry seasons, or live-in fresh water scarce areas. The quality of stored rainwater can deteriorate over time, due to increasing concentrations of contaminants... Read More about Managing potential pathogens in stored rainwater using small-scale in-situ electrochemical activation.

A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India (2022)
Journal Article
Fox, B., Thorn, R., Dutta, T., Bowes, M., Read, D., & Reynolds, D. (2022). A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India. Science of the Total Environment, 842, 156848. https://doi.org/10.1016/j.scitotenv.2022.156848

The quality and health of many of our vital freshwater systems are poor. To tackle this with ever increasing pressures from anthropogenic and climatic changes, we must improve water quality monitoring and devise and implement more appropriate water q... Read More about A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India.

The in situ production of aquatic fluorescent organic matter in a simulated freshwater laboratory model (2022)
Journal Article
Perrin, E. M., Thorn, R. M., Sargeant, S. L., Attridge, J. W., & Reynolds, D. M. (2022). The in situ production of aquatic fluorescent organic matter in a simulated freshwater laboratory model. Frontiers in Microbiology, 13, Article 817976. https://doi.org/10.3389/fmicb.2022.817976

Dissolved organic matter (DOM) is ubiquitous throughout aquatic systems. Fluorescence techniques can be used to characterize the fluorescing proportion of DOM, aquatic fluorescent organic matter (AFOM). AFOM is conventionally named in association wit... Read More about The in situ production of aquatic fluorescent organic matter in a simulated freshwater laboratory model.

A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India (2021)
Presentation / Conference
Fox, B., Thorn, R., Dutta, T., & Reynolds, D. (2021, April). A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India. Presented at EGU General Assembly 2021

With increasing pressures on water resources due to population, industrialization, agriculture, urbanization and climatic changes, improved temporal and spatial understanding of water quality is required. The development of new monitoring parameters,... Read More about A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India.

Water quality across the River Ganga basin in India: Trends, dominant geochemical processes and impacts (2021)
Presentation / Conference
Richards, L. A., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Water quality across the River Ganga basin in India: Trends, dominant geochemical processes and impacts. Presented at EGU General Assembly 2021

In a basin-wide survey of the River Ganga and key tributaries, from the Himalayan source to the Bay of Bengal in India, we aim to improve the conceptual understanding of downstream water quality trends along > 2000 km. Here we explore the spatial di... Read More about Water quality across the River Ganga basin in India: Trends, dominant geochemical processes and impacts.

Using in-situ sensors to quantify spatial variability in nutrient concentrations across the Ganges river basin (2021)
Presentation / Conference
Khamis, K., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Using in-situ sensors to quantify spatial variability in nutrient concentrations across the Ganges river basin. Presented at EGU General Assembly 2021

There is increasing interest in monitoring spatial variability in biogeochemical processes using field deployable sensors. Despite this, rigorous assessments of accuracy and optimal sensor configurations remain limited for such applications. We under... Read More about Using in-situ sensors to quantify spatial variability in nutrient concentrations across the Ganges river basin.

Taking the pulse of Mother Ganga - Revealing the visible and invisible water pollution crisis along the Ganges River (2021)
Presentation / Conference
Krause, S., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Taking the pulse of Mother Ganga - Revealing the visible and invisible water pollution crisis along the Ganges River. Presented at EGU General Assembly 2021

It is probably hard to overestimate the significance of the River Ganges for its spiritual, cultural and religious importance. As the worlds’ most populated river basin and a major water resource for the 400 million people inhabiting its catchment, t... Read More about Taking the pulse of Mother Ganga - Revealing the visible and invisible water pollution crisis along the Ganges River.

Sediment and surface water microplastic contamination along the Ganges River, from the Himalayan foothills to the tidal reach downstream of Kolkata, India (2021)
Presentation / Conference
Nel, H., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Sediment and surface water microplastic contamination along the Ganges River, from the Himalayan foothills to the tidal reach downstream of Kolkata, India. Presented at EGU General Assembly 2021

Twenty rivers have been estimated previously to account for almost 70% of global plastic emissions to the marine environment. Of these, the Ganges River was second only to the Yangtze River. Yet, scale and complexity of the Ganges River network make... Read More about Sediment and surface water microplastic contamination along the Ganges River, from the Himalayan foothills to the tidal reach downstream of Kolkata, India.

Going off-grid – The decentralised production of point-of-use drinking water (2021)
Digital Artefact
Clayton, G. E., Dutta, T. K., Fox, B. G., Thorn, R. M. S., & Reynolds, D. M. Going off-grid – The decentralised production of point-of-use drinking water. [https://www.waterlinepublication.org.uk/articles/going-off-grid-the-decentralised-production-of-point-of-use-drinking-water/]

Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms (2020)
Conference Proceeding
Clayton, G., Thorn, R., & Reynolds, D. (in press). Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms

Summary of key findings Direct disinfection of established Pseudomonas aeruginosa biofilms by electrochemically activated solutions [ECAS] exhibited significantly greater anti-biofilm activity compared to NaOCl and HOCl at free chlorine concentratio... Read More about Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms.

Resistance to echinocandin antifungal agents in the United Kingdom in clinical isolates of Candida glabrata: Fifteen years of interpretation and assessment (2019)
Journal Article
Fraser, M., Borman, A. M., Thorn, R., & Lawrance, L. M. (2020). Resistance to echinocandin antifungal agents in the United Kingdom in clinical isolates of Candida glabrata: Fifteen years of interpretation and assessment. Medical Mycology, 58(2), 219-226. https://doi.org/10.1093/mmy/myz053

Candidaemia is widely reported as the fourth most common form of bloodstream infection worldwide. Reports of breakthrough cases of candidaemia are increasing, especially in the context of a move away from azole antifungals as prophylactic or first li... Read More about Resistance to echinocandin antifungal agents in the United Kingdom in clinical isolates of Candida glabrata: Fifteen years of interpretation and assessment.

Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment (2019)
Journal Article
Clayton, G. E., Thorn, R. M., & Reynolds, D. M. (2019). Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment. Frontiers in Environmental Science, 7, Article 35. https://doi.org/10.3389/fenvs.2019.00035

© 2019 Clayton, Thorn and Reynolds. Point-of-use (POU) drinking water treatment systems provide solutions for communities where centralized facilities are unavailable. Effective POU systems treat and reduce the number of pathogens in POU water suppl... Read More about Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment.

Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system (2018)
Journal Article
Fox, B. G., Thorn, R. M., Anesio, A. M., Cox, T., Attridge, J. W., & Reynolds, D. M. (2019). Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system. Water, 11(1), Article 10. https://doi.org/10.3390/w11010010

© 2018 by the authors. Organic matter (OM) has an essential biogeochemical influence along the hydrological continuum and within aquatic ecosystems. Organic matter derived via microbial processes was investigated within a range of model freshwater sa... Read More about Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system.

Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS) (2017)
Journal Article
May, J., Robinson, G., Thorn, R., & Reynolds, D. (2017). Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS). Mutagenesis, 32(6), 622-623. https://doi.org/10.1093/mutage/gex033

Electrochemically activated solutions (ECAS) are of interest as potential disinfectants due to high biocidal activity against many microorganisms. They are widely used clinically in some countries (decontamination of surgical instruments and wounds),... Read More about Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS).

Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes (2017)
Journal Article
Clayton, G., Thorn, R., & Reynolds, D. M. (2019). Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes. Journal of Water Process Engineering, 30, Article 100480. https://doi.org/10.1016/j.jwpe.2017.08.018

© 2017 Elsevier Ltd Approximately 800 million people live without clean drinking water. Diarrhoea is responsible for between 1.7 and 2 million deaths each year (primarily children) which are the result of poor drinking water quality and sanitation. T... Read More about Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes.

The in situ bacterial production of fluorescent organic matter; An investigation at a species level (2017)
Journal Article
Fox, B. G., Thorn, R. M. S., Anesio, A. M., & Reynolds, D. M. (2017). The in situ bacterial production of fluorescent organic matter; An investigation at a species level. Water Research, 125, 350-359. https://doi.org/10.1016/j.watres.2017.08.040

© 2017 The Authors Aquatic dissolved organic matter (DOM) plays an essential role in biogeochemical cycling and transport of organic matter throughout the hydrological continuum. To characterise microbially-derived organic matter (OM) from common env... Read More about The in situ bacterial production of fluorescent organic matter; An investigation at a species level.