Outputs (33)

Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches (2019)
Journal Article

© 2019 H. P. Ellis et al. Glioblastoma is the most common primary adult brain tumour, and despite optimal treatment, the median survival is 12-15 months. Patients with matched recurrent glioblastomas were investigated to try to find actionable mutati... Read More about Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches.

Aluminium Induced DNA-damage and Oxidative Stress in Cultures of the Marine Sponge Hymeniacidon perlevis (2019)
Journal Article

Aluminium is the most abundant element in the earth crust, and has no known biological function. However, it is an established neurotoxicant in its trivalent oxidation state, with exposure resulting in neurodegenerative diseases like Parkinson’s dise... Read More about Aluminium Induced DNA-damage and Oxidative Stress in Cultures of the Marine Sponge Hymeniacidon perlevis.

Rapid bactericidal effect of cinnamon bark essential oil against Pseudomonas aeruginosa (2019)
Journal Article

AIMS:
This study aimed to identify the most effective antimicrobial from a selection of essential oils and investigate its bactericidal properties against Ps. aeruginosa.

METHODS AND RESULTS:
The disc diffusion assay and minimal inhibitory/bacte... Read More about Rapid bactericidal effect of cinnamon bark essential oil against Pseudomonas aeruginosa.

Cash water expenditures are associated with household water insecurity, food insecurity, and perceived stress in study sites across 20 low- and middle-income countries (2019)
Journal Article

Billions of people globally, living with various degrees of water insecurity, obtain their household and drinking water from diverse sources that can absorb a disproportionate amount of a household's income. In theory, there are income and expenditur... Read More about Cash water expenditures are associated with household water insecurity, food insecurity, and perceived stress in study sites across 20 low- and middle-income countries.

Les sciences cognitives: Un cadre pour unifier aujourd’hui la théorie et la pratique en psychothérapie? (2019)
Journal Article

This article discusses the proposition that cognitive science has now developed to the point where it can serve as an overarching meta-theory for field of psychotherapy. It will begin with an overview of the main strands of thinking which have emerge... Read More about Les sciences cognitives: Un cadre pour unifier aujourd’hui la théorie et la pratique en psychothérapie?.

Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML). (2019)
Presentation / Conference Contribution

Mesenchymal stromal cells (MSC) are known to protect leukemic cells from drug-induced toxicity within the bone marrow (BM) niche, however, less is known about leukemic impact on supportive MSC. The nucleoside-analogue, cytarabine (Ara-C), is a front-... Read More about Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML)..

A guide to architecture for the public health workforce (2019)
Journal Article

Background

Public health and environmental challenges facing the world in the 21st century, including the ageing population, increasing urbanisation, rise of non-communicable diseases and climate instability, require an interdisciplinary response.... Read More about A guide to architecture for the public health workforce.

Access to transport and life opportunities (2019)
Report

This report presents the findings from a study conducted by NatCen and the University of the West of England (UWE Bristol), commissioned by the Department for Transport (DfT) to investigate how access to transport affects the life opportunities and w... Read More about Access to transport and life opportunities.

How do they measure up? Differences in stakeholder perceptions of quality measures used in English community nursing (2019)
Journal Article

© The Author(s) 2019. Objectives: To establish how quality indicators used in English community nursing are selected and applied, and their perceived usefulness to service users, commissioners and service providers. Methods: A qualitative multi-site... Read More about How do they measure up? Differences in stakeholder perceptions of quality measures used in English community nursing.

Paramedic perceptions of bleeding in trauma and the use of tranexamic acid (TXA) (2019)
Presentation / Conference Contribution

Stakeholder requirements for an ethical framework to sustain multiple research projects in an emerging living lab involving older adults (2019)
Journal Article

© The Author(s) 2019. Living Lab (LL) research should follow clear ethical guidelines and principles. While these exist in specific disciplinary contexts, there is a lack of tailored and specific ethical guidelines for the design, development, and im... Read More about Stakeholder requirements for an ethical framework to sustain multiple research projects in an emerging living lab involving older adults.

Factors associated with quality of life in systemic sclerosis: a cross-sectional study (2019)
Journal Article

© 2019, The Author(s). Introduction: Systemic sclerosis (SSc) is a connective tissue disease characterized by progressive fibrosis of the skin and internal organs, leading to their failure and disturbances in the morphology and function of blood vess... Read More about Factors associated with quality of life in systemic sclerosis: a cross-sectional study.

TReatIng Urinary symptoms in Men in Primary Healthcare using non-pharmacological and non-surgical interventions (TRIUMPH) compared with usual care: Study protocol for a cluster randomised controlled trial (2019)
Journal Article

Background: Lower urinary tract symptoms (LUTS) can relate to urinary storage or voiding. In men, the prevalence and severity of LUTS increases with age, with a significant impact on quality of life. The majority of men presenting with LUTS are manag... Read More about TReatIng Urinary symptoms in Men in Primary Healthcare using non-pharmacological and non-surgical interventions (TRIUMPH) compared with usual care: Study protocol for a cluster randomised controlled trial.

Methods of identifying and recruiting older people at risk of social isolation and loneliness: A mixed methods review (2019)
Journal Article

Background
Loneliness and social isolation are major determinants of mental wellbeing, especially among older adults. The effectiveness of interventions to address loneliness and social isolation among older adults has been questioned due to the lac... Read More about Methods of identifying and recruiting older people at risk of social isolation and loneliness: A mixed methods review.

Action 3:30R: Process evaluation of a cluster randomised feasibility study of a revised teaching assistant-led extracurricular physical activity intervention for 8 to 10 year olds (2019)
Journal Article

Background: Numerous interventions to increase children's physical activity levels are published, yet, few studies report indicators of external validity. Process evaluations are critical for assessing intervention implementation, sustainability and... Read More about Action 3:30R: Process evaluation of a cluster randomised feasibility study of a revised teaching assistant-led extracurricular physical activity intervention for 8 to 10 year olds.

Contextualising the pervasive impact of macroeconomic austerity on prison health in England: A qualitative study among international policymakers (2019)
Journal Article

Background: Prisons offer the state the opportunity to gain access to a population that is at particularly high risk of ill-health. Despite the supportive legal and policy structures surrounding prison rehabilitation, the oppressive nature of the aus... Read More about Contextualising the pervasive impact of macroeconomic austerity on prison health in England: A qualitative study among international policymakers.

Complex regional pain syndrome: An international survey of clinical practice (2019)
Journal Article

Background: Published guidelines promote best practice in complex regional pain syndrome (CRPS) treatment and management; however, these recommendations are not always applied in clinical practice. Understanding existing care internationally will hel... Read More about Complex regional pain syndrome: An international survey of clinical practice.

Educational needs in people with ankylosing spondylitis and psoriatic arthritis: A cross-sectional study (2019)
Journal Article

Objective: To assess the educational needs of people with Ankylosing Spondylitis (AS) and Psoriatic Arthritis (PsA), test differences across patient subgroups and identify factors independently associated with their educational needs.

Methods: Thi... Read More about Educational needs in people with ankylosing spondylitis and psoriatic arthritis: A cross-sectional study.

Researching the Therapeutic Impact of Words (2019)
Presentation / Conference Contribution

This presentation outlines different projects researching therapeutic writing for disordered eating. It aims to disseminate these research findings as well as to describe some of the many obstacles to conducting and publishing research in this area.

Evaluation of antifungal activities and antihaemolytic effects of cinnamon essential oils from leaf and bark on Candida albicans and Candida auris (2019)
Presentation / Conference Contribution

Candida infections can be considered as a significant source of patient morbidity and mortality. Candida albicans is the most common pathogen causing Candida infections. Candida auris is a newly described pathogen that is associated with multi-drug r... Read More about Evaluation of antifungal activities and antihaemolytic effects of cinnamon essential oils from leaf and bark on Candida albicans and Candida auris.