All Outputs (6)

Anticancer effects of the Novel Pyrazolyl-Urea GeGe-3 (2024)
Journal Article
Williams, A., Cooper, E., Clark, B., Perry, L., Ponassi, M., Iervasi, E., …Ladomery, M. (2024). Anticancer effects of the Novel Pyrazolyl-Urea GeGe-3. International Journal of Molecular Sciences, 25(10), Article 5380. https://doi.org/10.3390/ijms25105380

In a screen of over 200 novel pyrazole compounds, ethyl 1-(2-hydroxypentyl)-5-(3-(3- (trifluoromethyl) phenyl)ureido)-1H-pyrazole-4-carboxylate (named GeGe-3) has emerged as a potential anticancer compound. GeGe-3 displays potent anti-angiogenic pr... Read More about Anticancer effects of the Novel Pyrazolyl-Urea GeGe-3.

A multiple criteria decision analysis to establish the use cases and candidate point of care tests to enter into a platform trial of multiple in vitro diagnostic point of care tests in the prehospital environment (2024)
Journal Article
Kirby, K., Coggins, J., Gibson, A., Liddiard, C., Moore, T. H., Savović, J., …Body, R. (2024). A multiple criteria decision analysis to establish the use cases and candidate point of care tests to enter into a platform trial of multiple in vitro diagnostic point of care tests in the prehospital environment. NIHR Open Research, 4, Article 29. https://doi.org/10.3310/nihropenres.13580.1

Background There are increasing demands on Emergency Medical Services. More efficient treatment pathways are required to support conveyance decision making and patient referral in prehospital care. Point of Care testing is increasingly available and... Read More about A multiple criteria decision analysis to establish the use cases and candidate point of care tests to enter into a platform trial of multiple in vitro diagnostic point of care tests in the prehospital environment.

Two novel Raoultella species associated with bleeding cankers of broadleaf hosts, Raoultella scottia sp. nov. and Raoultella lignicola sp. nov. (2024)
Journal Article
Brady, C., Cramptom, B., Kaur, S., Maddock, D., Kile, H., Arnold, D., & Denman, S. (2024). Two novel Raoultella species associated with bleeding cankers of broadleaf hosts, Raoultella scottia sp. nov. and Raoultella lignicola sp. nov. Frontiers in Microbiology, 15, 11. https://doi.org/10.3389/fmicb.2024.1386923

Seventeen Gram-negative, facultatively anaerobic bacterial strains were isolated from bleeding cankers of various broadleaf hosts and oak rhizosphere soil in Great Britain. The strains were tentatively identified as belonging to the genus Raoultella... Read More about Two novel Raoultella species associated with bleeding cankers of broadleaf hosts, Raoultella scottia sp. nov. and Raoultella lignicola sp. nov..

More than my appearance: A pilot evaluation of the expand your horizon online functionality-based writing programme for adults with visible differences (2024)
Journal Article
Guest, E., Halliwell, E., Mathews, A., Alleva, J., & Harcourt, D. (in press). More than my appearance: A pilot evaluation of the expand your horizon online functionality-based writing programme for adults with visible differences. Health Psychology and Behavioral Medicine,

Adults with conditions that affect their appearance, known as visible differences, can experience appearance concerns, social anxiety, and depression. Interventions have been developed for this population to facilitate adjustment and coping skills; h... Read More about More than my appearance: A pilot evaluation of the expand your horizon online functionality-based writing programme for adults with visible differences.

Nanoparticle and nanotopography-induced activation of the Wnt pathway in bone regeneration (2024)
Journal Article
Jagannathan, C., Waddington, R. J., & Ayre, W. (2024). Nanoparticle and nanotopography-induced activation of the Wnt pathway in bone regeneration. Tissue Engineering Part B: Reviews, 30(2), https://doi.org/10.1089/ten.TEB.2023.0108

Background and Aims: Recent research has focused on developing nanoparticle and nanotopography-based technologies for bone regeneration. The Wingless-related integration site (Wnt) signaling pathway has been shown to play a vital role in this process... Read More about Nanoparticle and nanotopography-induced activation of the Wnt pathway in bone regeneration.

An exploration of the direct biological targets of molecular hydrogen (2024)
Book Chapter
Hancock, J., May, J. E., LeBaron, T. W., Punampalam, R., & Russell, G. (2024). An exploration of the direct biological targets of molecular hydrogen. In J. Slezak, & B. Kura (Eds.), Molecular Hydrogen in Health and Disease (21-38). Springer. https://doi.org/10.1007/978-3-031-47375-3

Molecular hydrogen (H2), supplied either as a gas or in a solution, has been gaining popularity as a treatment for a variety of conditions and diseases. For example, it has been suggested to be beneficial for neurodegenerative diseases, to ease the i... Read More about An exploration of the direct biological targets of molecular hydrogen.