All Outputs (3)

Amino acid metabolism as a therapeutic target in cancer: A review (2021)
Journal Article
Endicott, M., Jones, M., & Hull, J. (2021). Amino acid metabolism as a therapeutic target in cancer: A review. Amino Acids, 53, 1169–1179. https://doi.org/10.1007/s00726-021-03052-1

Malignant cells often demonstrate a proliferative advantage when compared to non-malignant cells. However, the rapid growth and metabolism required for survival can also highlight vulnerabilities specific to these malignant cells. One such vulnerabil... Read More about Amino acid metabolism as a therapeutic target in cancer: A review.

The anti-cancer effect of Olea europaea L. products: A review (2021)
Journal Article
Antoniou, C., & Hull, J. (2021). The anti-cancer effect of Olea europaea L. products: A review. Current Nutrition Reports, 10, 99–124. https://doi.org/10.1007/s13668-021-00350-8

Purpose of Review: The olive tree (Olea europaea L.) has featured as a significant part of medicinal history, used to treat a variety of ailments within folk medicine. The Mediterranean diet, which is rich in olive products, is testament to Olea euro... Read More about The anti-cancer effect of Olea europaea L. products: A review.

New insights into the role of the branched-chain aminotransferase proteins in the human brain (2015)
Journal Article
Hull, J., Patel, V. B., Hutson, S. M., & Conway, M. E. (2015). New insights into the role of the branched-chain aminotransferase proteins in the human brain. Journal of Neuroscience Research, 93(7), 987-998. https://doi.org/10.1002/jnr.23558

© 2015 Wiley Periodicals, Inc. The human cytosolic branched-chain aminotransferase (hBCATc) enzyme is strategically located in glutamatergic neurons, where it is thought to provide approximately 30% of de novo nitrogen for brain glutamate synthesis.... Read More about New insights into the role of the branched-chain aminotransferase proteins in the human brain.